Conserved Protein Domain Family
bHLH_AtBPE_like

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cd18919: bHLH_AtBPE_like 
basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BIG PETAL (BPE) and similar proteins
The family includes several bHLH transcription factors from Arabidopsis thaliana, such as BPE, HBI1 and BEE proteins (BEE1-3). BPE, also termed AtbHLH31, or EN 88, is involved in the control of Arabidopsis petal size, by interfering with postmitotic cell expansion to limit final petal cell size. HBI1, also termed AtbHLH64, or homolog of bee2 interacting with IBH1, or EN 79, is an atypical bHLH transcription factor that acts as positive regulator of cell elongation downstream of multiple external and endogenous signals by direct binding to the promoters and activation of the two expansin genes EXPA1 and EXPA8, encoding cell wall loosening enzymes. BEEs, also termed protein Brassinosteroid enhanced expression, are positive regulators of brassinosteroid signaling.
Statistics
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PSSM-Id: 381489
Aligned: 20 rows
Threshold Bit Score: 162.226
Created: 16-Apr-2018
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative DNAputative dimer
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Comment:Based on the structure evidence that Arabidopsis thaliana MYC2 (5GNJ) binds DNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                    ##  ## ##   #                 ##                                 
Q0JXE7    132 DYIHVRARRGQATDSHSLAERARREKISERMKILQDLVPGCNKVIGKALVLDEIINYIQSLQRQVEFLSMKLEAVNSRMN 211 thale cress
Q9LK48    187 DYIHVRARRGQATDSHSLAERARREKISERMTLLQDLVPGCNRITGKAVMLDEIINYVQSLQRQVEFLSMKLATVNPRME 266 thale cress
Q6NKN9    202 NYIHMRARRGQATNSHSLAERVRREKISERMRLLQELVPGCNKITGKAVMLDEIINYVQSLQQQVEFLSMKLATVNPEIN 281 thale cress
Q8GY61    168 DYIHVRARRGQATDSHSIAERVRREKISERMKFLQDLVPGCDKITGKAGMLDEIINYVQSLQRQIEFLSMKLAIVNPRPD 247 thale cress
Q93VJ4    137 DYIHVRARRGEATDRHSLAERARREKISKKMKCLQDIVPGCNKVTGKAGMLDEIINYVQSLQQQVEFLSMKLSVINPELE 216 thale cress
Q9ZPW3    181 DYIHVRARRGQATDRHSLAERARREKISKKMKYLQDIVPGCNKVTGKAGMLDEIINYVQCLQRQVEFLSMKLAVLNPELE 260 thale cress
Q8GWK7    143 EVVHVRARRGQATDSHSIAERVRRGKINERLKCLQDIVPGCYKTMGMATMLDEIINYVQSLQNQVEFLSMKLTAASSYYD 222 thale cress
Q8GZ13    141 EVVHVRARRGQATDSHSLAERVRRGKINERLRCLQDMVPGCYKAMGMATMLDEIINYVQSLQNQVEFLSMKLTAASSFYD 220 thale cress
Q9LV17    149 DYIHVRARRGQATDRHSLAERARREKISEKMTALQDIIPGCNKIIGKALVLDEIINYIQSLQRQVEFLSMKLEVVNSGAS 228 thale cress
A4D998    100 DVVHVRAKRGQATDSHSLAERVRREKINERLKCLQDLVPGCYKAMGMAVMLDVIIDYVRSLQNQIEFLSMKLSAASACYD 179 thale cress
Feature 1           
Q0JXE7    212 PGIEVF 217 thale cress
Q9LK48    267 FNANAS 272 thale cress
Q6NKN9    282 IDIDRI 287 thale cress
Q8GY61    248 FDMDDI 253 thale cress
Q93VJ4    217 CHIDDL 222 thale cress
Q9ZPW3    261 LAVEDV 266 thale cress
Q8GWK7    223 FNSETD 228 thale cress
Q8GZ13    221 FNSETD 226 thale cress
Q9LV17    229 TGPTIG 234 thale cress
A4D998    180 LNSLDI 185 thale cress

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