Conserved Protein Domain Family
alpha_CARP_receptor_like

?
cd03122: alpha_CARP_receptor_like 
Carbonic anhydrase alpha related protein, receptor_like subfamily. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases. Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism. CARPs have lost conserved histidines involved in zinc binding and consequently their catalytic activity. This sub-family of carbonic anhydrase-related domains found in tyrosine phosphatase receptors may play a role in cell adhesion.
Statistics
?
PSSM-Id: 239396
Aligned: 14 rows
Threshold Bit Score: 301.966
Created: 31-Oct-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
AAC50439   67 GPEHWvt----------ssVSCG---------GRHQSPIDILd--qHARVGe---eYQELQLDgfdnessnktWMKNTGK 122  human
CAG01079   20 NQNHWak----------kfPSCS---------NAKQSPINIEenlaQVQRQ-----HQELTFEgwdqpttsrtSIKNDGK 75   Tetraodon nigrovi...
BAA97445   45 NQENWak----------kyPACN---------GAKQSPINIDedltQLNTN-----LKKLHFEgwheessaytLIRNTGK 100  African clawed frog
AAH78205   47 NQKHWvk----------kyPVCG---------NARQSPIDISeeftQVRLQ-----YQNLQLEnweqpttdstTITNDGK 102  zebrafish
AAC39934   45 NQKNWgk----------kyPTCN---------SPKQSPINIDedltQVNVN-----LKKLKFQgwdktslentFIHNTGK 100  human
AAB53054   35 APKFMesafktg-lnkvklDSLGkvln-vpslGRTQSPIDIVp---VITAFge--hLQNAHFEvtyes-tgefKAVNDGN 106  nematode
AAF46630   41 NLYSGrtif------qdvvNAVGnrrl-emklAKQPSPITIPes-nMIKRQl----KMPLHWTyyedl-pmatVLENNGN 107  fruit fly
AAF46638   82 YNYDWdq-----------gPHTWdt------aCNNQSPINIDm--nCVEINy---fDTPLIWShynsi-plgiRLENNGH 138  fruit fly
AAF58761   90 GPHTWl-------------PKSRsssssveeaTFFQSPVNIDe--sQIQRMairelLSWNHYDdlp----asiTLENTGQ 150  fruit fly
AAT66640   48 NAKNGllnrvkldslgkvlHVSGl--------GRYPSPIDIVp---VITCFge--hLQNAEFRveyhn-tgdfRATNSGN 113  Ostertagia ostertagi
AAC50439  123 TVAILLKd------------------dYFVSGaglpgRFKAEKVEFHWGhsn-gsaGSEHSINGRRFPVEMQIFFYNpdd 183  human
CAG01079   76 TGTFLKDpvvhlterflssvavnvggdFYVSGgalrsKFKVGRITFHWGrcnastdGSEHSVDGARYPLEVGMQIYCyqp 155  Tetraodon nigrovi...
BAA97445  101 TVEINLTd------------------dYFLSGgaldsQYKASWITFHWGkcnatsdGSEHSLEGQKFPLEMQIFCFNhke 162  African clawed frog
AAH78205  103 TVVIGLNs------------------eYFISGgglrsRFKVGRITFHWGrcnatsdGSEHSLNGNRFPLEMQIYCFDdle 164  zebrafish
AAC39934  101 TVEINLTn------------------dYRVSGgvsemVFKASKITFHWGkcnmssdGSEHSLEGQKFPLEMQIYCFDadr 162  human
AAB53054  107 SIWLMREgns---------------seLAISFlp-eeQYHLDAVNFHWAtep--mnGSEHTIGGVGYAGEMHLIHRNtrf 168  nematode
AAF46630  108 TVIMRIYtan--------------nfmPQLSGaellgRYQFVEAIFKWGs-----lKSEHSIGKHNFCLELQALHRCaql 168  fruit fly
AAF46638  139 TLILRAAfpe---------------rtPSIDGgdllgRFDFREISFRWSwas--slGSEHTLDHHHSPLEMQCLHTDgdg 201  fruit fly
AAF58761  151 TLILRAQfhg---------------naPTISGadllaSYTFLELRFHWGwcn--seGSEHTINHRKFPLEMQVMHKTgsg 213  fruit fly
AAT66640  114 AVWLLREgnd---------------seLAVSFlp-eeQYHLDSITWHWGtep--mnGSEHTIGGVGYAGELHLIHRNtrf 175  Ostertagia ostertagi
AAC50439  184 fdsf--qtaisenRIIGAMAIFFQVsprDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPAsl--gSYYRYTGSLTTP 259  human
CAG01079  156 qssqsldesikagGRIAALAVLFEIsseDNSNYGAIVDGVRAVSRYGKSAQVSAFTLGGLLPNst--eKYFTYSGSLTTP 233  Tetraodon nigrovi...
BAA97445  163 feni--deaisanGKIKALSILFKVgqeDNVHYNTIIDGVNNVHRFGRKVALEPFILSDLLPDyt--dKYYTYNGSLTTP 238  African clawed frog
AAH78205  165 fesi--deamssgGKIAAVAVLFEAsieDNQDYAAIIEGVNNVSRFGKSSAVEEFSLLALLPEnt--eKYFMYNGSLTAP 240  zebrafish
AAC39934  163 fssf--eeavkgkGKLRALSILFEVgteENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNst--dKYYIYNGSLTSP 238  human
AAB53054  169 atma---dalkqpNGVIAIAVFLNEshdDNAVFSPLINLLPQVIYKGSECKLCSFDFQTFFPVaektkEFWMYEGSETTD 245  nematode
AAF46630  169 ----------nnnFEYLTLSYLFALshvKNEHLKQVTDHLKWISQPGSSIELPPFHLESLLQPfg--sGYFSYEGTYDNG 236  fruit fly
AAF46638  202 cd------gcsssQGVLMISYMFDLs-eHNPFLDVLIQHLAAVEQAGQVVEVPPFPLSYLMSPfy--dKFYSYNGSLTEP 272  fruit fly
AAF58761  214 ipr-----tctssYDLLMIGYVFELs-aHNPFLDPLVQNLRLVQKPGKRVQISPFPISYLMYQfr--sGFYSYGGSLTHP 285  fruit fly
AAT66640  176 ptme---lalkqpNGVLAIAIFLNEshdENPAITPFIELLPNITYKGNEVRVGQFNFGALFPSpektkEFWMYEGSETVE 252  Ostertagia ostertagi
AAC50439  260 PCSEIVEWIVFRRPVPISYHQLEAFYSiftteqqdhvksveylRNNFRPQQRLHDRVVSK 319  human
CAG01079  234 PCSETVEWIVFRNPAAISEEQVFAGGAan-------------pPGDSPEQVSSVSRTGLA 280  Tetraodon nigroviridis
BAA97445  239 PCSESVEWIVFKDTVTISESQLEMFCEiltmqqsgyvmvmdylQNNYRHQQYTFSGQVFS 298  African clawed frog
AAH78205  241 PCSENVEWIVFKNTVGISETQLEVFCEvmtiqqagyamltdylQNNYREQQQQFMGQVFS 300  zebrafish
AAC39934  239 PCTDTVDWIVFKDTVSISESQLAVFCEvltmqqsgyvmlmdylQNNFREQQYKFSRQVFS 298  human
AAB53054  246 PFRETVNWIVIRAALPISSHQLDKLREvragryde-efsdkvpMKPLRPIQNPSSRTIQS 304  nematode
AAF46630  237 DVVLPTTWLINRKISVVDSRQLSEFEAlygrn-------gnrnCKNGREKQPLGNRNVYF 289  fruit fly
AAF46638  273 PCHRGAEWLIYPESLAISERQLNEFRQlrdrr-------gsriARNARPVQPIGDRMVYL 325  fruit fly
AAF58761  286 PCYQGTEWFIFPESLAISDFQLRHFRLllgpd------gispiARNSRPVQHMGNRVVSL 339  fruit fly
AAT66640  253 PFRETVQWLVFRSAVPISSYQLDRLREvrsggyd---eeretpMEPIRPPQPPNSRSVVC 309  Ostertagia ostertagi
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap