Conserved Protein Domain Family
myo_inos_iolG

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TIGR04380: myo_inos_iolG 
inositol 2-dehydrogenase
All members of the seed alignment for this model are known or predicted inositol 2-dehydrogenase sequences co-clustered with other enzymes for catabolism of myo-inositol or closely related compounds. Inositol 2-dehydrogenase catalyzes the first step in inositol catabolism. Members of this family may vary somewhat in their ranges of acceptable substrates and some may act on analogs to myo-inositol rather than myo-inositol per se. [Energy metabolism, Sugars]
Statistics
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PSSM-Id: 275173
Aligned: 26 rows
Threshold Bit Score: 393.123
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_03636697    1 MLKIGIIGFGRIGKVHARSIQTRvENACVL-RICDPFMnPAMEAEAQKLGIqRWGTDAGELIHDPEIDAVLICSSTHTHA 79  Holdemania fili...
WP_012771004   1 MFNIALLGAGRIGQVHAVNIAEH-RETCLY-SVVDPNP-ANAQALSDKYQA--RLQTIDEAMADPAVHAVLIASATDTHA 75  Dickeya zeae
WP_011925300   3 IMRFGLLGAGRIGRIHGLNVSSR-GDARLV-AVADASN-EAALSLAQATGAe--VADADAIIADAKIDAILICTPTDTHA 77  Bradyrhizobium ...
WP_010919173   1 MHDIAILGAGRIGRIHAKNVASQ-PGLRLK-YVVDPVA-AAADGLAGETGAs--VADLETALNDPAVAGVIVASSTDTHL 75  Caulobacter vib...
WP_012875466   3 KLRVALLGAGRIGSFHARTIAYSvPNARLA-FIADVAG-SLAESLAKELEVeRWSDDPLEAIERPDIDAVVIATPGNTHA 80  Thermobaculum t...
WP_013481020   1 MFEVAVIGAGRIGRIHARNVAAH-PALHLK-AIVDPVG-DSAAELAKALGSe--VSTFEAVLADPKVKGVIIASPTDQHL 75  Asticcacaulis e...
WP_012875463  15 PIGVGIIGLGRIGALHADHLMNAiRGARLVrAAVDP-A-HKKKLEAEGYPI-PLTDDPGALINDPEVEAVVIASPSTFHY 91  Thermobaculum t...
WP_013255551   3 KIKIGSVGLGRLGLRHAENLASKiMGAQLI-ALCDVDD-RKLNDTADRLGVaHRFSDFEAMLKLPELDAVLIASPSALHT 80  Spirochaeta sma...
WP_005690025   5 EVKIGIVGLGRLGKIHATNLATKiPHAKLQ-AATSVVP-EELAWARQELGVeETYEDFDDMVQHADIDAVFIVSPSGFHL 82  Lactobacillus r...
WP_013177724   2 TLGFGVIGAGRIGALHARHLAGAvDGARLV-AVMDAN--PEAAGRSAFSGAaAVTS-VEALLRHPGVEAVVIASPTDLHA 77  Truepera radiov...
ZP_03636697   80 ALSIEAAQAGKHIFCEKPVDPDPKRITEVIAAVEKA-GVHFQVGFNRRFDHNFKALRQAVEQGKVGDPHFITVLSRDPEA 158 Holdemania fili...
WP_012771004  76 DLIELAARHGKAIFCEKPVHLDIARVRDCLKVVEQQ-QVPLFVGFNRRYDPQFRRVKTLAGEGRIGKPESLMIISRDPSP 154 Dickeya zeae
WP_011925300  78 DLIEAAVSAGKAVFCEKPVDLDSDRICRCLATVEKA-GKPLMIGFNRRFDPNFAALEKRLRNGEAGEIEIVSIISRDPAP 156 Bradyrhizobium ...
WP_010919173  76 DYSLKAIAAGKAVFCEKPIDQDLARARSASGELGGK-GVKLFLGFNRRFDPNFQGLKARLSAGVVGALETVHITSHDPAP 154 Caulobacter vib...
WP_012875466  81 ALIQAAASAGKHIFCEKPIALELPEIDNALEVVERH-GVKLQIGFQRRFDSGFLKARDMIRKGEIGKLYMLRSVTRDPQL 159 Thermobaculum t...
WP_013481020  76 TQTLQCIAAGKAVLCEKPLDQDLETARGAAAQLGG--DKPLLLGFNRRFDRHFGALKQQLEAGRIGALESLLIVSHDPAP 153 Asticcacaulis e...
WP_012875463  92 EHIVLVTEARKPLFCEKPLADNVPDAMKAADKIRTS-GIPFQIGFQRRFDPGYRRARQLIEQGCIGVPELFKGVTCD-RI 169 Thermobaculum t...
WP_013255551  81 GQISSALAAGKHVFTEKPLGVTVEECKAAEKAVEKYpDRVFMIGFMRRFDDSYMYAHEKVISGQIGRPILFRSYSQDPEK 160 Spirochaeta sma...
WP_005690025  83 PQIESAMQAGKHVFSEKPIGLDLDAIKHTQAVIADHpELKFQLGFMRRFDDSYVYAKQLVDAGKIGDITLIRSYSIDPAA 162 Lactobacillus r...
WP_013177724  78 EQIRLAAAAGKAIFCEKPVALGLRETQEALRAVSAA-GVPFQIGFNRRFDPGYAEVARAVHALELGRPEMFRSQSSDPAP 156 Truepera radiov...
ZP_03636697  159 ---PSLDYVK-----VSGGMFMDMTIHDFDMVRYLSGSEVSEVYAVGDALVNPQIKELgDIDSAQITLRFENGAIGCISN 230 Holdemania fili...
WP_012771004 155 ---PPAEYVR-----VSGGMFRDMTIHDFDMVRFIMGEEPVSVFAQGSNLVDPAIGAAgDIDTAFVVFKFASGAMATIVN 226 Dickeya zeae
WP_011925300 157 ---PPVDYVK-----RSGGLFRDMMIHDFDMARFLLAEEPVEVFALGSALVDKAIGEAgDVDTAAVLMKTASGRIAQISN 228 Bradyrhizobium ...
WP_010919173 155 ---PPVSYVK-----VSGGLFKDMTIHDFDMARWLLDEPVSEVFAAASCLVDPAIGEAgDVDTAKILLRTASGKICMISN 226 Caulobacter vib...
WP_012875466 160 ---PDENYMK-----TCGGLFRDTMVHDFDIIRFLSGLEVEEIYASGSALVDPMVERYqDVDNAVVVMKLQGGVIATIEN 231 Thermobaculum t...
WP_013481020 154 ---PPVSYVK-----VSGGLFKDMAIHDFDMARFILGEEIVEVYAAAACLVDPAIGEAgDVDTAKTTLKTASGRLCVISN 225 Asticcacaulis e...
WP_012875463 170 ---PSVDYLK-----TSGGLFWDLGVHDFDAARFLTGLEIESVYAHGAVLVDKQLEEIdDVDYGLVILRFSSGAMGVVHN 241 Thermobaculum t...
WP_013255551 161 fidGAIAFAP-----HSGGEFLDMAVHDIDLARWFLQDEPESVYAIGGCYAHPEFAQYkDGDNVSCLMKFRNEAMAFLFA 235 Spirochaeta sma...
WP_005690025 163 ---GMESFVKfatsaNSGGLFLDMSIHDIDVIRWLTGKEIDKVWAIGLNRAYPVLDQAgELETGAALMQLEDKTMAILVA 239 Lactobacillus r...
WP_013177724 157 ---PPRAYAA-----VSGGLYLDSAIHDLDTARFIMG-EVTRVTALGRVLVADYLGDYgDVDTSIVTLEFASGALGVVQN 227 Truepera radiov...
ZP_03636697  231 SRRAAYGYDQRAEVFGSRGSAATQNDTPST-LI-LSDEQGVQQEKPLYfFLERYMQSFADEIASFTEAIVENKPTAVNGR 308 Holdemania fili...
WP_012771004 227 SRRSGYGYDQRLELHGELGVLSAGNIRENQ-VE-HWGDAGCLAAKPEHfFLQRYRDAYAAEWRHFVEVLHGRTRPECSGV 304 Dickeya zeae
WP_011925300 229 SRRASYGYDQRVEVHGAKGMLRAGNVHETT-VE-IATGQGFRADPVQNfFLERYSAAYRAELSAFIDVCAGKAAPSPSGR 306 Bradyrhizobium ...
WP_010919173 227 SRRSGYGYDQRIEAFGSKGLVRADNVMEST-VS-IWGENGAASDAFQNfFLDRYAEAYRREMAHFAEIIRGEALPSVGYV 304 Caulobacter vib...
WP_012875466 232 SRQAVYGYDVRAEVLGSEGAIRIEHSHETP-VT-HYSRTGV-CEDHVYwFIERFASAYRAEILSFIRSVIEDTEPAVTGI 308 Thermobaculum t...
WP_013481020 226 SRRSGYGYDQRLEAYGQKGLLKADNVLEST-VA-HWGAEGPVLDAFQNfFLDRYAEAYRSEIAHFADIVAGKAKPMVGYD 303 Asticcacaulis e...
WP_012875463 242 AWRAPWGYEIRAEVYGSKGKVVTELDEKFP-TR-LYDQRGIVIDR-HTlFTERFRDAYRDEIQAFVDAILAGKIPSPGVD 318 Thermobaculum t...
WP_013255551 236 GRTAPHGYNVETEIIGTKGTLRIASVPQKNlVE-VLDSHGVRRECSEN-FLERFSASYVNEVQEFVDSIRYRRKPAVTVY 313 Spirochaeta sma...
WP_005690025 240 GRNAAHGYHVETEIIGTKGMLRVAQVPEKN-LVtVMNEEGIIRPTSQN-FPERFAQAFLSEEQAFVDSILTGETVGITAE 317 Lactobacillus r...
WP_013177724 228 SRRTVHGYDLRVEVHGERGKLVTEVERATP-VW-RYGESGVRGD-YIHyFLERFRDAYRLELQAFVDAVREGRAPTPGAE 304 Truepera radiov...
ZP_03636697  309 DGLIPVLMAKAALKSMREHRPVT 331 Holdemania filiformis DSM 12042
WP_012771004 305 DGERALYLADKALESLATGRAVS 327 Dickeya zeae
WP_011925300 307 DGLRAQMLADAATLSARGGRPVA 329 Bradyrhizobium sp. ORS 278
WP_010919173 305 DGVEALALAEAAGLSAKTGQVVK 327 Caulobacter vibrioides
WP_012875466 309 DGRKATVLGLAADRSLRTGKPVR 331 Thermobaculum terrenum
WP_013481020 304 DAVRALELAEAAAYSVATGQVVR 326 Asticcacaulis excentricus
WP_012875463 319 DAVKALLVADAATRSRKSRDWVQ 341 Thermobaculum terrenum
WP_013255551 314 DGTKVSEIAYRCKEAFERGTMLR 336 Spirochaeta smaragdinae
WP_005690025 318 DGLQGTKAALALQRAYEKNDIVK 340 Lactobacillus rhamnosus
WP_013177724 305 DAVAALKLALAATLSLREGRPVe 327 Truepera radiovictrix
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