Conserved Protein Domain Family
2a57

?
TIGR00939: 2a57 
Equilibrative Nucleoside Transporter (ENT)
[Transport and binding proteins, Nucleosides, purines and pyrimidines]
Statistics
?
PSSM-Id: 273352
Aligned: 11 rows
Threshold Bit Score: 360.958
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
AAC32597  33 AFMCGVSMMMPVNAVFSAPAYIMTYYRYAMQDPEAVPLYTNFWNN-----------------VMTYYNLIGIVTSLIMEP 95  Leishmania donovani
AAC39526  18 FFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTGPEda-------------fnFNNWVTLLSQLPLLLFTL 84  human
AAC39526   1 -margdaprdsyhlvgisffilglgtllpwnffitaipyfqarlagagnstarilstnhtgpedafnfnnwvtllsqlpl 79  human
Q61672     1 --margnaprdsyhlvgisffilglgtllpwnffitaipyfqgrlagtnssaetmgtnhtsptdtfnfnnwvtllsqlpl 78  house mouse
AAB88050  18 FFILGLGTLLPWNFFITAIPYFQGRLAGT-NSSAETPSTNHTSPTdt-------------fnFNNWVTLLSQLPLLLFTL 83  Norway rat
AAB88049  18 FFVLGLGTLLPWNFFITATQYFTSRLNTSQNISLVTNQSCESTEAladpsvslparsslsaiFNNVMTLCAMLPLLIFTC 97  Norway rat
AAC51103  18 FFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQAsaapaaplpernslsaiFNNVMTLCAMLPLLLFTY 97  human
AAC18807  46 YFTLGVGFLLPWNAFITAVDYFSYLYPST--AVDRIFAVIY-----------------------MLVALVCLFVIVVFYA 100 thale cress
AAA98003  29 VILVGFGVLLPWNMFITIAPEYYVNYWFKPDGVETWYSKEFMG----------------------SLTIASQLPNASINV 86  Caenorhabditis elegans
P31381    81 FFAIGIGLLWPWNCILSASQYFKHDIFKDTSIWAKIFTSSMMS--------------------------FSTISSMLFNI 134 Saccharomyces cerev...
AAD45279  16 FLFFGMSVVVVTNSIFSMPFFFIEYYKYAQGKPDAKPEDPKFWKH-----------------MFTYYSIAAFVVELVLAS 78  Trypanosoma brucei
AAC32597  96 LTLLSWFRrIPMKVRLLG----GLVILIVEIIVLMVVPARGTSEAGAVATICCTGFIGGFGKSIFESTTYGMFGAFPSSF 171 Leishmania donovani
AAC39526  85 LNSFLYQC-VPETVRILG----SLLAILLLFALTAALVKVDMSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTY 159 human
AAC39526  80 llftllnsflyqcvpetvrilgsllailllfaltaalvkvdmspgpffsitMASVCFINSFSAVLQGSLFGQLGTMPSTY 159 human
Q61672    79 llftllnsflyqcipesvrilgsllailllfaltaalvkvdlspglffsvtMASVWFINSFCAVLQGSLFGQLGTMPSTY 158 house mouse
AAB88050  84 LNSFLYQC-IPESVRILG----SLLAILLLFALTAALVKVDLSPGLFFSITMASVWFINSFCAVLQGSLFGQLGTMPSTY 158 Norway rat
AAB88049  98 LNSFLHQK-VSQSLRILG----SLLAILLVFLVTATLVKVQMDALSFFIITMIKIVLINSFGAILQASLFGLAGVLPANY 172 Norway rat
AAC51103  98 LNSFLHQR-IPQSVRILG----SLVAILLVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASY 172 human
AAC18807 101 HKSLASFR-IN--LGLLL----FVIALLVVPVLDLVYVKGQVGLYAGFDVTSAAVALSGLGDALMQGGLIGVAGEMPERY 173 thale cress
AAA98003  87 FNLFLIIA-GPLIYRVFApvcfNIVNLTIILILVIVLEPTEDSMSWFFWVTLGMATSINFSNGLYENSVYGVFADFPHTY 165 Caenorhabditis elegans
P31381   135 YLAKRQYK-YSR--RVINg--lVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEY 209 Saccharomyces cerev...
AAD45279  79 LMLTPIGRrISVTVRLGVg----LVIPIVLVFSVMMVTIVTTTETGAKVTIMLIAIANGVAMTLCDAGNAALIAPFPTKF 154 Trypanosoma brucei
AAC32597 172 TSTMMGGVGMSGVLTSLLQIIVKAALPDsyegVKKQSKIYYGLDVGIQGMTFVALILLRFNSFAQNYFgdlgavkskvda 251 Leishmania donovani
AAC39526 160 STLFLSGQGLAGIFAALAMLLSMASGVD----AETSALGYFITPYVGILMSIVCYLSLPHLKFARYYL------------ 223 human
AAC39526 160 STLFLSGQGLAGIFAALAMLLSMASGVD----AETSALGYFITPYVGILMSIVCYLSLPHLKFARYYL------------ 223 human
Q61672   159 STLFLSGQGLAGIFAALAMLMSLASGVD----AQTSALGYFITPCVGILLSIVCYLSLPHLKFARYYL------------ 222 house mouse
AAB88050 159 STLFLSGQGLAGIFAALAMLTSLASGVD----PQTSALGYFITPCVGILLSIICYLSLPHLKFARYYL------------ 222 Norway rat
AAB88049 173 TAPIMSGQGLAGFFTSVAMICAVASGSK----LSESAFGYFITACAVVILAILCYLALPWMEFYRHYL------------ 236 Norway rat
AAC51103 173 TAPIMSGQGLAGFFASVAMICAIASGSE----LSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQ------------ 236 human
AAC18807 174 MQAVVAGTAGSGVLVSLLRILTKAVYPQdpdgLRKSANLYFAVGIVVMVICAVFYNVAHKLPVIKFHE------------ 241 thale cress
AAA98003 166 IGALLIGNNICGLLITVVKIGVTYFLNDe---PKLVAIVYFGISLVILLVCAIALFFITKQDFYHYHH------------ 230 Caenorhabditis elegans
P31381   210 SQGVMVGQAVAGVLPSLVLFALAFIENSsv-sTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENW------------ 276 Saccharomyces cerev...
AAD45279 155 YSSVVWGIAVCGVVTSFFSIVIKTSMEGgyhnMLIQSRIYFGLVMFMQVISCALLVLLRKNPYAQKYAaefr-------- 226 Trypanosoma brucei
AAC32597 252 gklsaealchtdEHPTHdKEGRNSSSGKEVPALGEvQTAAAKSEGPDAVEESSWPHEVEG-PTSNEIL--------VATA 322 Leishmania donovani
AAC39526 224 ------------ANKSSqAQAQELETKAELLQSDE-NGIPSSPQKVALTLDLDLEKEPESePDEPQKP--------GKPS 282 human
AAC39526 224 ------------ANKSSqAQAQELETKAELLQSDE-NGIPSSPQKVALTLDLDLEKEPESePDEPQKP--------GKPS 282 human
Q61672   223 ------------TEKLSqAPTQELETKAELLQADEkNGVPISPQQASPTLDLDPEKEPEP--EEPQKP--------GKPS 280 house mouse
AAB88050 223 ------------TKKPq-APVQELETKAELLGADEkNGIPVSPQQAGPTLDLDPEKELELgLEEPQKP--------GKPS 281 Norway rat
AAB88049 237 ------------QLNL--AGPAEQETKLDLISEGE---EPRGGREESGVPGPNSLPANRN------------------QS 281 Norway rat
AAC51103 237 ------------QLKL--EGPGEQETKLDLISKGE---EPRAGKEESGVSVSNSQPTNES------------------HS 281 human
AAC18807 242 ------------ERKN-----------EELIREKS-------EEKGSLT-GLAWR-----------------------TT 267 thale cress
AAA98003 231 ------------QKG------------MEIREKAE-------TDRPSPS------------------------------I 249 Caenorhabditis elegans
P31381   277 ------------NVEDG---HITDVLLGSLRSNEEeIRIVGRIDQMEDEDHRRTNGTRDDnDEGEELQ--------LKVP 333 Saccharomyces cerev...
AAD45279 227 ---------yaaRKGIDdKGAGGDEGNGAAKGPADqDDDPHGGDDTDKGNVMTATVDPDTmKDMDQVEsittsqqmLMAR 297 Trypanosoma brucei
AAC32597 323 IFSTLRRVKWMFVACAFNFLITLFLFPGIAVGMFPD-----SK--------WFSTIAVFIFNVFDVLGRFsPSLKLMWPR 389 Leishmania donovani
AAC39526 283 VFTVFQKIWLTALCLVLVFTVTLSVFPAITAMVTSSts-pgKWsq-----fFNPICCFLLFNIMDWLGRS-LTSYFLWPD 355 human
AAC39526 283 VFTVFQKIWLTALCLVLVFTVTLSVFPAITAMVTSSts-pgKWsq-----fFNPICCFLLFNIMDWLGRS-LTSYFLWPD 355 human
Q61672   281 VFVVFRKIWLTALCLVLVFTVTLSVFPAITAMVTTSsnspgKWgl-----fFNPICCFLLFNVMDWLGRS-LTSYFLWPD 354 house mouse
AAB88050 282 VFVVFRKIWLTALCLVLVFTVTLSVFPAITAMVTTSsnspgKWsq-----fFNPICCFLLFNVMDWLGRS-LTSYFLWPD 355 Norway rat
AAB88049 282 IKAILKSIWVLALSVCFIFTVTIGLFPAVTAEVESSiagtsPWkn----cyFIPVACFLNFNVFDWLGRS-LTAICMWPG 356 Norway rat
AAC51103 282 IKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSiagssTWer-----yFIPVSCFLTFNIFDWLGRS-LTAVFMWPG 355 human
AAC18807 268 LWDIVTKVKSHGFGIVLLYMVTLSIFPGYITEDVHSel-ltDw---------YPILLIAAYNVFDLVGKC-LTAVFMLED 336 thale cress
AAA98003 250 LWTTFTNCYGQLFNVWFCFAVTLTIFPVMMTVTTRGdsgflNKimsendeiYTLLTSFLVFNLFAAIGSI-VASKIHWPT 328 Caenorhabditis elegans
P31381   334 FEVLFAKLKYLVLSIFTTFVVTL-VFPVFASATYVTglplsNa--------QYIPLIFTLWNLGDLYGRV-IADWPMFRD 403 Saccharomyces cerev...
AAD45279 298 VWNVFWRVWPMLFACFMVFFTTFLVYPAVYFAIKADtg-----------dgWYLTIAAALFNLGDFLSRLcLQFKALHVS 366 Trypanosoma brucei
AAC32597 390 SYKQrwIIVAASFARVIFVPLLLLHSYH------------YIPGEAYGYVMEVIFGFSNGYVGSMALVLGPQSkgIDNdG 457 Leishmania donovani
AAC39526 356 EDSR--LLPLLVCLRFLFVPLFMLCHVPqrsr-----lpiLFPQDAYFITFMLLFAVSNGYLVSLTMCLAPRQ--VLP-H 425 human
AAC39526 356 EDSR--LLPLLVCLRFLFVPLFMLCHVPqrsr-----lpiLFPQDAYFITFMLLFAVSNGYLVSLTMCLAPRQ--VLP-H 425 human
Q61672   355 EDSQq-LLPLLVCLRFLFVPLFMLCHVPqhar-----lpiIFRQDAYFITFMLLFAVSNGYLVSLTMCLAPRQ--VLP-H 425 house mouse
AAB88050 356 EDSQ--LLPLLVCLRFLFVPLFMLCHVPqrar-----lpiIFWQDAYFITFMLLFAISNGYFVSLTMCLAPRQ--VLP-H 425 Norway rat
AAB88049 357 QDSR--WLPVLVACRVVFIPLLMLCNVKqhhy-----lpsLFKHDVWFITFMAAFAFSNGYLASLCMCFGPKK--VKP-A 426 Norway rat
AAC51103 356 KDSR--WLPSLVLARLVFVPLLLLCNIKprry-----ltvVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKK--VKP-A 425 human
AAC18807 337 EK----IAVGGSIARLLFYPLFWGCLHGp----------mFLRTEIPVTILTCLLGLTNGYLTSVLMILAPKS--VPL-R 399 thale cress
AAA98003 329 PR----YLKFAIILRALFIPFFFFCNYRvqtr----aypvFFESTDIFVIGGIAMSFSHGYLSALAMGYTPNV--VPS-H 397 Caenorhabditis elegans
P31381   404 QKFTprKTFIYSLLRVAAIPLFLMFTAItssssgdeehngSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQ--LDNdD 481 Saccharomyces cerev...
AAD45279 367 PR----WVLIGTFARMLPIIPLVLCVRS------------IITGPWLPYILVHAWGFTYGYYGGISQIYAPRTgsLTTaG 430 Trypanosoma brucei
AAC32597 458 KRFVAGTLMGISILVGGTIGTVLSIMTQTIR 488 Leishmania donovani
AAC39526 426 EREVAGALMTFFLALGLSCGASLSFLFKALL 456 human
AAC39526 426 EREVAGALMTFFLALGLSCGASLSFLFKALL 456 human
Q61672   426 EREVAGALMTFFLALGLSCGASLSFLFKALL 456 house mouse
AAB88050 426 EREVAGALMTFFLALGLSCGASLSFLFKALL 456 Norway rat
AAB88049 427 EAETAGNIMSFFLCLGLALGAVLSFLLRALV 457 Norway rat
AAC51103 426 EAETAGAIMAFFLCLGLALGAVFSFLFRAIV 456 human
AAC18807 400 HSETAGIVTVMFLVVGLASGSVIAWFWVI-- 428 thale cress
AAA98003 398 YSRFAAQLSVCTLMVGLLTGGLWAVVIEHFV 428 Caenorhabditis elegans
P31381   482 EKEAAGGFTNIFVSTGLALGSIISYVFVFII 512 Saccharomyces cerevisiae S288c
AAD45279 431 ERSLAANWTIISLLGGIFVGAMFALAVNEGL 461 Trypanosoma brucei
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap