3ZZI,3U6U,1GS5,2AP9


Conserved Protein Domain Family
argB
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TIGR00761: argB 
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acetylglutamate kinase
This model describes N-acetylglutamate kinases (ArgB) of many prokaryotes and the N-acetylglutamate kinase domains of multifunctional proteins from yeasts. This enzyme is the second step in the "acetylated" ornithine biosynthesis pathway. A related group of enzymes representing the first step of the pathway contain a homologous domain and are excluded from this model. [Amino acid biosynthesis, Glutamate family]
Links
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Statistics
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PSSM-Id: 273256
Aligned: 15 rows
Threshold Bit Score: 232.172
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3ZZI_A        50 FAVIKVGGAIIS--Dn--LHELASCLAFLYHVGLY-P-IVLHGTGPQVNGRLEAQGIEPDYIDGI-----RITDEHTMAV 118 baker's yeast
P11445         4 PLIIKLGGVLLD--SeeaLERLFSALVNYRESHQRpL-VIVHGGGCVVDELMKGLNLPVKKKNGL-----RVTPADQIDI 75  Escherichia coli
Q92BB9         4 TIVIKLGGVASDn----lTDDFFQQIIKWQAEKKK-I-VLVHGGGHYITKMMKALDIPVETKKGL-----RVTNKQALEV 72  Listeria innocu...
O08320         4 LIVIKIGGQAISq----lSTTFFDQIAQWYQQHYQ-I-LIVHGGGPMINRLTTQLALPVHKVNGL-----RVTDAATLVL 72  Lactobacillus p...
P94989        30 VVVVKYGGNAMT--DdtlRRAFAADMAFLRNCGIH-P-VVVHGGGPQITAMLRRLGIEGDFKGGF-----RVTTPEVLDV 100 Mycobacterium t...
WP_000668895   3 FIVIKIGGSTLS--Dm--HPSIINNIKHLRSNNIY-P-IIVHGGGPFINEALSNQQIEPHFVNGL-----RVTDKATMTI 71  Staphylococcus ...
O50147         1 MIVVKVGGAEGI--N---YEAVAKDAASLWKEGVK-L-LLVHGGSAETNKVAEALGHPPRFLTHPggqvsRLTDRKTLEI 73  Thermus thermop...
3U6U_A         1 MIVVKVGGAEGI--N---YEAVAKDAASLWKEGVK-L-LLVHGGSAETNKVAEALGHPPRFLTHPggqvsRLTDRKTLEI 73  Thermus thermop...
1GS5_A         4 PLIIKLGGVLLDseEa--LERLFSALVNYRESHQR-PlVIVHGGGCVVDELMKGLNLPVKKKNGL-----RVTPADQIDI 75  Escherichia col...
2AP9_A        27 VVVVKYGGNAXT--DdtlRRAFAADXAFLRNCGIH-P-VVVHGGGPQITAXLRRLGIEGDFKGGF-----RVTTPEVLDV 97  Mycobacterium t...

3ZZI_A       119 VRKCFLEQ-NLKLVTALEQLGVRARPITSG---VFTA--D----YLD-----------KDk-------YKLVGNIKSVTK 170 baker's yeast
P11445        76 ITGALAGTaNKTLLAWAKKHQIAAVGLFLGdgdSVKV--T----QLD-----------EE--------LGHVGLAQPGSP 130 Escherichia coli
Q92BB9        73 TKMVLIGQvQPAITTAFQKRNISVIGLNAGdtgLLEA--D----QIN-----------DSd-------LGFVGKITKVKT 128 Listeria innocu...
O08320        73 TKLALLGDaQPALLAKLTQHHLPVLGLNAAdnqLLTG--E----LID-----------YRq-------LGYVGRLTAVNQ 128 Lactobacillus p...
P94989       101 ARMVLFGQvGRELVNLINAHGPYAVGITGEdaqLFTA--Vr--rSVT-----------VDgva---tdIGLVGDVDQVNT 162 Mycobacterium t...
WP_000668895  72 TKHTLIADvNTALVAQFNQHQCSAIGLCGLdaqLFEI--T----SFD------------Qq-------YGYVGVPTALNK 126 Staphylococcus ...
O50147        74 FEMVYCGLvNKRLVELLQKEGANAIGLSGLdgrLFVG--RrktaVKY-----------VEngkvkvhrGDYTGTVEEVNK 140 Thermus thermop...
3U6U_A        74 FEMVYCGLvNKRLVELLQKEGANAIGLSGLdgrLFVG--R----RKTavkyvengkvkVHr-------GDYTGTVEEVNK 140 Thermus thermop...
1GS5_A        76 ITGALAGTaNKTLLAWAKKHQIAAVGLFLGdgdSVKV--T----QLD-----------EE--------LGHVGLAQPGSP 130 Escherichia col...
2AP9_A        98 ARXVLFGQvGRELVNLINAHGPYAVGITGEdaqLFTAvrR----SVT-----------VDgva---tdIGLVGDVDQVNT 159 Mycobacterium t...

3ZZI_A       171 EPIEASIKAGALPILTSLAE-TASGQMLNVNADVAAGELARVFEPLkIVYLNEKGGIING--STGeKISMINLDeEYDDL 247 baker's yeast
P11445       131 KLINSLLENGYLPVVSSIGV-TDEGQLMNVNADQAATALAATLGAD-LILLSDVSGILDG--KGQ-RIAEMTAA-KAEQL 204 Escherichia coli
Q92BB9       129 ALIEQLLAENIITVIAPLGI-NSAHDWLNVNADTAACEVASALNAEaLYLLTDVPGVKNG---AK-IIDEIATD-EINKL 202 Listeria innocu...
O08320       129 VQLMQLLAHHIG-ILAPLAL-TETGQWLNVNADMAATVLAQQLHAEkLVLLTDVPGIIHH---GN-VMTSLSPQ-QAQQL 201 Lactobacillus p...
P94989       163 AAMLDLVAAGRIPVVSTLAP-DADGVVHNINADTAAAAVAEALGAEkLLMLTDIDGLYTRwpDRDsLVSEIDTG-TLAQL 240 Mycobacterium t...
WP_000668895 127 DALQYLCTK-FVPIINSIGFnNHDGEFYNINADTLAYFIASSLKAP-IYVLSNIAGVLIN--Dv--VIPQLPLV-DIHQY 199 Staphylococcus ...
O50147       141 ALLDLLLQAGYLPVLTPPAL-SYENEAINTDGDQIAALLATLYGAEaLVYLSNVPGLLARypDEAsLVREIPVE-RIEDP 218 Thermus thermop...
3U6U_A       141 ALLDLLLQAGYLPVLTPPAL-SYENEAINTDGDQIAALLATLYGAEaLVYLSNVPGLLARypDEAsLVREIPVE-RIEDP 218 Thermus thermop...
1GS5_A       131 KLINSLLENGYLPVVSSIGV-TDEGQLMNVNADQAATALAATLGAD-LILLSDVSGILDG--KGQ-RIAEMTAA-KAEQL 204 Escherichia col...
2AP9_A       160 AAXLDLVAAGRIPVVSTLAP-DADGVVHNINADTAAAAVAEALGAEkLLXLTDIDGLYTRwpDRDsLVSEIDTG-TLAQL 237 Mycobacterium t...

3ZZI_A       248 MKQSWVKYGTKLKIREIKELLDYLPRSSSV 277 baker's yeast
P11445       205 IEQGIITDGMIVKVNAALDAARTLGRPVDI 234 Escherichia coli
Q92BB9       203 QTTDIIKGGMIPKLASAAFAAENGVGQVII 232 Listeria innocua Clip11262
O08320       202 IRTAVITAGMQPKVQAAIAAIQTGVKQAII 231 Lactobacillus plantarum WCFS1
P94989       241 LPT--LESGMVPKVEACLRAVIGGVPSAHI 268 Mycobacterium tuberculosis
WP_000668895 200 IEHGDIYGGMIPKVLDAKNAIENGCPKVII 229 Staphylococcus aureus
O50147       219 EYLALAQGRMKRKVMGAVEAVRGGVKRVVF 248 Thermus thermophilus HB27
3U6U_A       219 EYLALAQGRMKRKVMGAVEAVKGGVKRVVF 248 Thermus thermophilus HB8
1GS5_A       205 IEQGIITDGMIVKVNAALDAARTLGRPVDI 234 Escherichia coli BL21(DE3)
2AP9_A       238 LPT--LELGXVPKVEACLRAVIGGVPSAHI 265 Mycobacterium tuberculosis CDC1551
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