Conserved Protein Domain Family
PRK05560

?
PRK05560: PRK05560 
DNA gyrase subunit A; Validated
Statistics
?
PSSM-Id: 235502
Aligned: 979 rows
Threshold Bit Score: 1159.79
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
285018500   4 SAKEIIQVNLEDEMRKSYLDYAMSVIVGRALPDARDGLKPVHRRVLFAMN-ELGAHSNKPYYKSARIVGDVIGKYHPHGD 82  
21228522   14 vrAGVTPILIDDEMKRSYINYAMSVIVGRALPDARDGLKPVHRRILFSMN-ESGITHDKPYKKSARIVGDVLGKYHPHGD 92  
124485240   7 ttHKTVSINIEDEMKNCFIDYAMSVIIGRAIPDVRDGLKPVHRRILYAMFhDEGNTSDKAYKKSAKAVAATMGNYHPHGD 86  
126179354   4 EGEGVVPINIEEEMKSCYIDYAMSVIIGRAIPDARDGLKPVHRRTLYAMW-EMGNTSDKPYKKSARIVGDVMGKYHPHGD 82  
154151175  12 ETHKTEPISIEQEMKTSFINYAMSVIIQRAIPDVRDGLKPVHRRSLYAMW-DMGNTSDKPTKKSARVVGDVMGKYHPHGD 90  
219851687  10 IIPKVIPVNIEDEMKSSYIDYAMSVIIGRAIPDIRDGLKPVHRRTLYAMW-EEGNTSDKAYKKSARAVAGTMGKYHPHGD 88  
294495526  20 EGGRVVPVLIQDEMKRSYIDYSMSVIVGRALPDARDGLKPVHRRILHSMN-EAGITHDKAYKKSARVVGDVLGKFHPHGD 98  
298675299  22 tgEDISPVLIEEEMKKSYIDYAMSVIVGRALPDARDGLKPVHRRILYSMK-EAGITYDKPYKKSARVVGDVLGKFHPHGD 100 
73670269   69 gqSGVTSILIENEMKRSYINYAMSVIVGRALPDARDGFKPVHRRVLFAMK-EAGITHDKPYKKSARVVGDVLGKYHPHGD 147 
91772466   26 tsERIVPILIQDEMKNSYIDYAMSVIVGRALPDARDGLKPVHRRILYAMK-EAGMTYDKAYKKSARVVGDVLGKYHPHGD 104 
285018500  83 QSVYDTLVRMAQPFSLRYMLVDGQGNFGSVDGDSAAAMRYTEARMSRLTHELIADIDKETVDFQPNYDEKEQEPSVMPTR 162 
21228522   93 SAVYDTIVRMVQDFSLRYPLIDGQGNFGSIDGDSAAAMRYTEVRMDRIAEEMLVDIEKETVPFIPNYDGSLKEPEVLPAR 172 
124485240  87 SAIYDTLVKMAQPFSYRYTLVDGQGNFGSIDGDSAAAMRYTEARLTKAAESLLEDIDKETVDFVPNFDESSQEPDVLPSR 166 
126179354  83 SAIYDTLVKMAQPFSYRCMLVDGQGNFGSIDGDSAAAMRYTEARLTKISEELLTDIDKKTVDFVPNFDESLQEPSVLPAR 162 
154151175  91 ASIYDTIVKMAQPFSYRHPLVQGQGNFGSVDGDAAAASRYTEVRLFPYAEALLEDLDKETVEFVPNYDESLKEPTVLPSK 170 
219851687  89 ASIYDTLVKMAQPFSYRIPLVDGQGNFGSIDGDSAAAMRYTEARLTRYAEELLADLDKKTVDFTPNFDSSTEEPTVLPSK 168 
294495526  99 TAVYDSLVRMVQDFSLRYPLIDGQGNFGSVDGDSAAAMRYTEVRMDKITTEMLEDIKKGTVDFKPNYDGSLEEPEVLPSK 178 
298675299 101 MAVYDSLVRMVQEFSMRYPLVDGQGNFGSIDGDSAAAMRYTEVRMEKISEEMLVDIDKETVPFQPNYDGALTEPTVLPAK 180 
73670269  148 TAVYDTIVRMVQDFSLRYPLIDGQGNFGSIDGDSAAAMRYTEVRMDRIAEEMLVDIDKETVPFMPNYDGSMEEPEVLPAK 227 
91772466  105 TAVYDSLVRMVQEFSLRYPLIDGQGNFGSIDGDSAAAMRYTESRMDRISNEMLADIDKETVLYRPNYDGSLKEPTVLPAR 184 
285018500 163 FPNLLVNGSAGIAVGMATNIPPHNLTESINACIALIDNPQIDVDGLMEYIPGPDFPTAGIVNGTAGIIAGYRTGRGRVRM 242 
21228522  173 LPNLLINGSTGIAVGMATNMPPHNISEVIDGILMLIENPETQISELMTVIKGPDFPTGAHILGTAGIRSAYMTGRGPIRM 252 
124485240 167 IPNLLVNGTTGIAVGMATNMMPHNLGEVCDLVDAYIDNPEMSLEEMMKILPAPDFPTGGKIMGTDGIVNAYQTGQGKVVL 246 
126179354 163 IPNLLVNGSSGIAVGMATNMPPHNLREVCEATCRVIDDAGTSTEELMQVMPGPDFPTGGIMMGTAGIRDAYLTGRGKCVV 242 
154151175 171 IPNLLVNGTDGIAVGMATKMPPHNLREVCAAVNRFLDEPSVPVEELLKIMPGPDFPTGGILMGVDGVKNIYATGQGRIVV 250 
219851687 169 VPNLLVNGTSGIAVGMATNMPPHNLREVCSAVEMTIKNPDCTVEDLMQVMPGPDFPTGGLITGTEGIVSAYHTGYGKLTV 248 
294495526 179 LPNLLLNGSTGIAVGMATNMAPHNLGEVVDATVKLIDDPETELAELRKIVKGPDFPTGGIIMGTSGIKSAYETGRSPIYL 258 
298675299 181 LPNLIVNGSTGIAVGMATNIPPHNLKEVADGLLMMIDNPDVSIPELRTAIKGPDFPTAGTILGTEGIKSAYETGRGRIKI 260 
73670269  228 LPNLLVNGSTGIAVGMATNMAPHNIGEVIDGILMLIENPDITIPELMTVIKGPDFPTGAHILGTAGIKSAYMTGRGALKI 307 
91772466  185 LPNLLINGSTGIAVGMATNMAPHNLGEVIDATLMLIEDPETPISSLMEIVKGPDFPTGGVILGHQGIKSAYETGRGPIKI 264 
285018500 243 RARAEIEiQd---nGREAIVVTEIPYQVNKARLIEKIAELVKEKKLEGISELRDESDKDGMRIYIEVKRGEAADVVLNNL 319 
21228522  253 RAVAEIQ-Elk--kDRQQIIVTELPYQVNKAKLIENIAQLVREKVINGISDLRDESDREGIRVVVELSRGVNPNVVLNQL 329 
124485240 247 RGIAEIE-Erk--kgFEQIVITEIPYQVNKAAMIEKIADLVKSKTIEGISDIRDESDKDGIRVIIELKQNTQANVVLNLL 323 
126179354 243 RGVAEIEeEg----rTPQIIITEIPFQVNKARLIEHIASLVRDKRIEGIGDIRDESDRDGMRIVVELKRGAAPQVILNFL 318 
154151175 251 RGVAEIE-EseggnrGDRIIVTELPYQVNKAQWITAIADMVKDKKLDGISDIRDESDKDGIRVVFELRKGTISAVILNNL 329 
219851687 249 RGVAEIE-Dve--tkTPKIIISEIPYQVNKARMVELIATLVKEKKIEGISDLRDESDRDGLRVVVDLKKGVIPTVVLNQL 325 
294495526 259 RAVTEIE-Emk--nDKYRIVVYELPYQVNKARLVESIANLVRDKKIEGISDLRDESGREGMRVVIELKKAANPKVLLNQL 335 
298675299 261 RSVADIE-Emk--nDKHRIVVSELPYQVNKANLIESIASLVRDKKIQGISDLRDESDREGIRIVIELARNTNPNVILNQL 337 
73670269  308 RAVAEIQ-Efk--kDRQRIIVTELPYQVNKARMIENIAQLVREKTIMGISDLRDESDREGIRVVIELSRGTNPKVVLNQL 384 
91772466  265 RAVTSIE-Emk--nDKKRIVVSELPYQVNKSRLIENIAALVREKKIVGISDLRDESDRDGIRVSIELTRNTNPEVILNQL 341 
285018500 320 YQQTQMESVFGINMVALVDGRPQLLNLKQMLEAFVRHRREVVTRRTIFELRKARARAHILEGLTVALANIDEMIELIKTS 399 
21228522  330 YKHTQMATTFGVINLALVDGKPKELNLKQLLEIYLEYRMEIIQKRTLYDLRKSEERAHILEGLRIALDNIDAVVALIKGS 409 
124485240 324 YKHTQLESSFGIINLAIVDKKPKILSLAELLRHFIAHRVDVVRRRSLFDLRKAEERMHILSGLLKALDMIDVVIATIRAS 403 
126179354 319 YKHTALESSFGIINLAIVDRQPRTLNLKEIIHEFLKHRVDVVRRRTEFDLTKNEERMHILRGLLVALDNIDAVIATIRGS 398 
154151175 330 YRFTALESGFSAYNLAIVDGTPKLLNLPALLGNFVHHRIEVIRRRSEFDLKKCQERVHILNGLLTALASIDKIIAAIRGS 409 
219851687 326 YKHTPLESTFGIINLAISDNQPKVLGLKAIISEFLHHRATVVRRRCEFDLKKAKDRLHILLGLLVALDRIDEVIATIRQS 405 
294495526 336 YKQTQLETTFGIINLALVDGVPRVLNLRELIQIYLKHRIDVISRRTVFDLRKAEERAHILQGLKVALDNIDEVIKLIRGS 415 
298675299 338 YKHTQLQVTYGIINLALVDGVPKVLNLYELLQIYLNHRMDVIQKRSQYQLRKAEERAHILDGLKICLGNLDEVISFIRNS 417 
73670269  385 YKHTQMETTFGVINLALVDGKPKELNLKELLEIYLEYRMEIIQKRTLYDLRKSEERAHILDGLKIALDNIDEVVALIKGS 464 
91772466  342 YKHTQMQTTFGIINLALVDNIPRELTLKELLQIYLEHRIDVILKRSMFDMRKADEKAHILKGLMIALDHIDEVIALIRGS 421 
285018500 400 ANPTEARERMLAKtwqpglvgallsaagaeasrpddlpsgvglgaggYQLTEVQATQILEMRLHRLTGLEQERLTEEYKQ 479 
21228522  410 ANADQAKQGLIDN----------------------------------FALDEVQAKAILEMRLQRLTGLETRKILDELEA 455 
124485240 404 PEVSVAQEALVSK----------------------------------LGFSEAQAEAILKMQLRRLAALEQQKILDETTS 449 
126179354 399 GTTDEAQKALVAK----------------------------------FALDEVQADAILKMQLRRLAALEHQKILDERDA 444 
154151175 410 DTVDNARIALISG----------------------------------FGLDELQANAILQMQLRRLAALEQQKIVDEKST 455 
219851687 406 ASSEAAQKALIAT----------------------------------FGLTEPQTVAILQMQLRRLAALEQAKIRDERDS 451 
294495526 416 STTEEAREGLISN----------------------------------FDLDEIQAKAILDMKLQRLTGLERQKIDEEYNG 461 
298675299 418 KTTPEAKEGLIEK----------------------------------FQLDEAQAKAILDMRLQNLTAIEQDKIESEYNE 463 
73670269  465 ANADEAKKGLMEN----------------------------------FALDEIQSKAILDMRLQRLTGLETKKVLEELEG 510 
91772466  422 NAVDEAKEGLMTR----------------------------------FGLDEVQAKAILDMRLQKLTGLERQKIEDEHGE 467 
285018500 480 LLEAISGLIRILENPDVLLEVIREELVSIREEYGDARRTEIRHSE-EDL-DILDLIAPEDVVVTLSHAGYAKRQPVSAYR 557 
21228522  456 LVKQIEELRKILASDELKYEIIRTELSELKDKYGDIRRTRIVHNT-ENV-TDEDLIPEEDVVVTITNSGYIKRIPLDTYT 533 
124485240 450 LQLVIDKLTWILSSEENILSVVKTETSEIRTAYADERRTQIDYTAnTDF-NVMDLIPDEQTLVMLTTQNYIKRVPLDLYR 528 
126179354 445 IAAEIERLSAILASEASILAEIKKELVDIGARFGDERRTRIAQA--AEAfDREDLIEDKPVLVSLTSSNYVKRIDLDTYR 522 
154151175 456 LEAEILKLETILASEENIKDEIRRETSEIALKFGDARRTEIT-LDaSDL-STEDLIEDKTVLVSITTANYIKRMDLDTYR 533 
219851687 452 LAHVIAELERILSCEANIYEEIRKEIVDVGERYGDDRRTEIT-CSqTIL-EREDLIEDKPVLISITTQNYIKRLPLETYR 529 
294495526 462 LIDTIADLKDILANDERKYAIIRDEVLELKDKYGDERRTLIQSSR-EEL-ADEDLIPEEEVVVTSTQSGYIKNIPLQTYN 539 
298675299 464 LVEKIADLKEIIASDSRKYNIIKDELTELKENYADERRTDIQSSD-EEL-SEEDLIPEEDVLITITNSGYIKRLPVTTYS 541 
73670269  511 LVKLIGELNKIIESDELKYEIIRNELLELKEKYGDARRTKIMQAA-SEV-REEDLIHEEEVVVTITNGGYIKRIPLKTYT 588 
91772466  468 LVKLIEDLKDIIESDERKYSIIKEELHAIRERFADKRRTEITGSH-VEF-EDEDLIPVEEVIVTITNSGYIKRMPVDTYS 545 
285018500 558 AQRRGGRGRSAAATKEEDFIDHLWLVNTHDTLLTFTSSGKVFWLPVYQLPEAGPNARGRPVINWIPLEQGERVQAVLPVr 637 
21228522  534 MQRRGGRGIIGMEMKEEDFVENLFISSTHNYILFFTNRGRLYWQKVYEIPEGSRQSRGKAIVNLLELQEGEMVNAMISVe 613 
124485240 529 QQKRGGRGVIGMTTKDEDSVDKVFLANTHDYLLCFTNKGRVYWLRVYEIPEGSRTSKGKAIVNLLNLT-DEEVSAVIPMr 607 
126179354 523 NQRRGGHGVIGMATKDNDGVEKVFVANMHDNLLCFTDRGRMYWLKIYDLPEGQRTGKGKALVNLLNLDGEERVTTVIPVr 602 
154151175 534 KQRRGGHGITGMTTKEDDVVSSVFAAGMKDYLLCFTNIGRVYWLKVYQIPESSRIAKGKPIVNLLNLK-DEVVTTVIPIr 612 
219851687 530 MQRRGGRGVIGMATKDEDSVEDIFVASMHDYLLCFTTDGRVYWLKVYNIPEASRTSKGKAIVNLLELQ-DELITAVIPIr 608 
294495526 540 MQHRGGRGVRGMETKEDDTVGSIFVASTHDYILFFTNRGKVYWQKVYDIPRGSRQSRGKAIVNLLELAEGESVNAMIPVh 619 
298675299 542 KQHRGGRGVAGINVKDDDFVEDVFVASTRDYLLLFTNKGRVNCKKVYEIPQGSKQSRGKALVNLFELENDEAVSSMITVk 621 
73670269  589 MQHRGGRGIIGMEMKEEDFVENLFISSTHNYILFFTNLGRLYWEKVYEIPEGSRQSRGKAIVNLLELKGGETINAMIPVk 668 
91772466  546 QQHRGGKGVIGMETKEQDVVEDIFISSTHDYLMFFTNRGKVHWKKVYGLPEGSRQSKGKAVVNLLDLAENESVTATITVk 625 
285018500 638 eyadGHYVFFATRKGMVKKTPLSEFAYQLKRGKVAINLDEGDALVDVALTDGERDVLLFASNGKTVRFserpkdEEvdev 717 
21228522  614 efaedKYLFMATRAGTVKKTPLSEFRNPRRAGIIAVSLDEGDELVKVLLTDGKQEIMMVSKKGKAIRF------SE---- 683 
124485240 608 dfdaeKNLLYATKKGRVGKFSQDLFSRPRTGGIIGITLLDGDELVDVVVTDGSTDVVLTTAFGQALRF------SE---- 677 
126179354 603 eyrpdHHLFFATRNGTVAKMALDEFSRPRQTGINAINLRDGDALVDVKATDGNQELILTTKFGQSLRF------HE---- 672 
154151175 613 efrkdRYLLFATQLGQVIKIPQDEFSFPRSTGTNAIRLRENDKLVDVITTDNTKEVVLSTRFGYGLRF------HE---- 682 
219851687 609 tfrhdRYLLFSTEQGQVVKVPQDQFSRPRSTGINAISLRENDSLVDVKLTDGTKELILSTRKGQSLRF------HE---- 678 
294495526 620 dfenDRYLFMGTRDGTVKRCSLSDFSNPRKAGIIAISLKEGDELVNVLQTDGNQDIMLASRHGKALRI------SE---- 689 
298675299 622 efsddWNLLMATKYGTVKKTPLSSFKTRKKSGLIAINLNENDELVNVILTDGQNDIILVSSTGKAIRF------AE---- 691 
73670269  669 efdknHYLLMATREGTIKKTPLSEFKNPRKAGIIAVTLDEDDELVRVLLTDGKKEVLIVSKKGKAIRF------SE---- 738 
91772466  626 efeedKFLFMATRMGTVKKTPLSDFSNVRKAGIIALKLDEGDELVNVALTDGSKEIMMVSRHGKAIRF------CE---- 695 
285018500 718 avdeaaaddalaaddeaagedgdetrgarrksrgG-VKPTGRSSRGVRGIRL--A-K--SEyVVSLIVAepaegqdedaD 791 
21228522  684 ----------------------------------EdVRPMGRTARGVRGMTLe-GpD--DE-VVSLDLV----------- 714 
124485240 678 ----------------------------------DeVRATGRGTQGVIGIRLk-FeG--DY-VCALTLV----------- 708 
126179354 673 ----------------------------------EaVRPVHRNAMGVRGIKLrhG----DA-LQAIAIV----------E 703 
154151175 683 ----------------------------------DtVRIVGRGASGVIGMRLr--gN--DT-IVALTLV----------- 712 
219851687 679 ----------------------------------QtVRTVGRNASGVRGIKLk--yG--DL-VQAATVV----------- 708 
294495526 690 ----------------------------------EdVRVMGRTARGVRGMKL----AgpDV-IVSLDVV----------D 720 
298675299 692 ----------------------------------TnVRPMGRAAQGVRGIRLn--pD--DR-IISMDTI----------S 722 
73670269  739 ----------------------------------KdVRPMGRTARGVRGMALd-GpE--DE-VVSLDIV----------- 769 
91772466  696 ----------------------------------RdVRPMGRTARGVRGMRLt-Gd---DI-VVSLDIV----------- 725 
285018500 792 DadlaqeaEadaqtrtaddadaYILTATENGYGKRTPLGEYPRKGRGTQGVIGIQTSERNGKLVGAVLLSVKDEVLLISD 871 
21228522  715 --------Det----------tTLLTVTDNGFGKRTEYSQYPVHRRGGKGVITIVTNLRNGFVSNVKSVAEDDELMFTSA 776 
124485240 709 Et-------------------qYLLMITDKGFGKRTEFEEFRGHGRGTQGVKSIVANFERGKVVSSLAVSDDDQVIITTA 769 
126179354 704 Dd--------------------HLLTITEQGYGKRTEFDEYRGHGRGTLGVRNIVVDARAGNVVGSMAVSDDDEIIVMSA 763 
154151175 713 Ek-------------------dHLLSITDAGFGKRTEFDDFRGHGRATMGVKNMQVERDV--VIHSRAVADTDEIFVMTA 771 
219851687 709 Ek-------------------dHLLTITELGYGKRTEFDEFRGHGRGTMGVRNILTAPQNG-VVATKAVSSDDEIVVMSA 768 
294495526 721 S-------Dg------------TLLTVTENGFGKRTPFDEYRTLRRGGQGVITIFTDMRNGPVVTVKTVEDDDEIILTSS 781 
298675299 723 D-------Den----------aKLLTITQNGYGKRTKFEEYRRMNRGGRGVTTIQMTPRNGPVVNVKTVRDDDDIVVTSY 785 
73670269  770 --------Det----------tTLLTVTENGFGKRTEYSQYPAHRRGGKGVITIITNERNGPVSRVRSVADDDELIFTSA 831 
91772466  726 --------Dls----------tKLLTITENGYGKRTTFDEYRGMKRGGQGVITIVTSLRNGPVINVKAVKEEDEVMVTSS 787 
285018500 872 GGTLVRTRASEISRVGRNTQGVTLIRLSKGEKLQAVERLDGSlveeE 918 
21228522  777 EGIIIRIPAKDISIQGRNTQGVRVMNIKSGDKVGGMARIKNG----K 819 
124485240 770 GGVVLRTSASDISIQGRGTKGVRVIRVDSGDKVTSVAIVPPDedepa 816 
126179354 764 SGIVIRTKVSEISIQKRGTRGVRVMKLDDGDRVIGFTILDSEe--pE 808 
154151175 772 SGVVIRTSVNSIRITGRGAKGVKIMRLDEKDKVIGVAIVTPEpgvea 818 
219851687 769 LGNVIRMKVSDISVQKRSARGVRIIRLDEDDRVVGLAVLQQE----I 811 
294495526 782 AGIVMRIPVTDIRVQGRNTKGVKIMNIREKDKLVSLARIKKEe---- 824 
298675299 786 QGLVIRIPVKDIRVQGRNTQGVKIMNMRENDKVIGVARIKKD----D 828 
73670269  832 DGIIIRIPAKDISIQGRNTQGVRIINLKSGDKVAGIARIQNG----K 874 
91772466  788 EGIFIRIPVKDIRAQGRNTQGVKIMNVRPGDKVVGVARIKNE----E 830 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap