Conserved Protein Domain Family
PRK04366

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PRK04366: PRK04366 
aminomethyl-transferring glycine dehydrogenase subunit GcvPB
Statistics
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PSSM-Id: 235292
Aligned: 303 rows
Threshold Bit Score: 640.622
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
148655660   1 MHNHEPPIFELSG-PGKIGVNLPQIDVPq--------SELPADLLRADDlAGLPELTEPEVIRHYTRISQRNFAIDTTM- 70 
111025248  11 PVWNEPIIMEMGY-PGRRGAVFSHAEDGiearvgaavDLIPTAVRRGDR-PALPEMSEPEVLYHYLRLSQQTLGM-MGV- 86 
271968916  26 ARWDEPIIFEQSR-PGRRGIAVPAAGVPa--------VELPESVRRAEP-PKLPEMAQLHVLRHYVRLSQENLGVDQAIa 95 
146304428   5 AYWDEPLITEYKG-KGRQGFLVPKEDLDv-------eIKLPEKIKRGKE-PELPEVSELEVVRHFVRLSQMSFGVDTGM- 74 
170290222  13 ARWEEPIIFELSN-EGERGILIPLDDKIvrev-gdvlSSIPEHMRRKDP-PKLPEVSQMRVLKHYLRLSQETLGADLNId 89 
170291056  12 DNVLEPSLFEIGRaEGGTVVAEPEEELVsllg--gieRIIPGNLIRKE--LKLPGLSEPEVARHFNHLAQMNYGVDSGP- 86 
226315350  26 AKWDEPVIFELSQ-PGERGVEVPPVEPQivetvgdgiSQLPDSLRRKKR-PNLPEVSQYRVIRHYSRISQEVLGSDFNVe 103
256391230  29 ARWDEPLIFELSS-PGERGVGVPVTDLPv--------PSLPAGLARAAA-PLLPEMSQPHVLRHYMRLSQETLGVDLNVd 98 
291300222  29 ARWDESLIFEQSK-PGQRGVLPPSVEPEiadavgdpaAALPDELKRATP-PALPELSQLEVLRHYLRLSQENLGVDFNId 106
70607137    5 AKWDEPLITEYKG-NGRVGTLITHDDSLrkei----tlnIPENLKRRNE-PNLPSISELEAVRHYIRLSQMSFGVDTGF- 77 
148655660  71 VSLGSCTMKYNSKLHEEAARLPGFAAAHPLQGDELSQGALQLMYELQAYLGEISGFDAVSLQPAAGAQGELTGILVFRAY 150
111025248  87 SLFGTCTMKYNPQVNEALAWRPEVTEVHPLQHEDTLQGTLEIVHGMDLILRELSGMDQFVFQAGGGAEAAFVNASVTRAY 166
271968916  96 VGQGTCTMKYSPKVNDRFVSDPKVAELHPLQPDDTVQGVLEVYWRMERMLAEISGMHRVSLQPASGSAAIYANIAMIRAY 175
146304428  75 MPLGSCTMKYNPKIEEETGVA---DRTHPLQDQDTVQGNLEVMYEMQRWLAEATGMDECSLQVPAGSAGELAGVLMIRKY 151
170290222  90 IGQGTCTMKYSPKVNERFVAM--VRELHPYQDEETVQGALEIMYKLDLFLREISGLDRFSFQPGGGSQAIFAMASIIRAY 167
170291056  87 YWLGSCTMKYTPKLVMRVADHQALRDMHPYSPEELTEGLLSILYELQEMLSKITGLPHYTLQPAAGAQGEFVGTLIIRKK 166
226315350 104 IGQGTCTMKYSPKINERFVRSPKMAELHPLQDESTVQGMLEMTYQLDLYLREISGMDKFSFQPGSGTQALFTQASIVRKY 183
256391230  99 IGQGTCTMKYSPKVNDSFVRDARIAELHPLQDEGTVQGVLEILYRLEGLLKEISGMDRVSLQPGSGSSAIYANVSMIRAY 178
291300222 107 IGQGTCTMKYSPKVNDQLVAGHKLAELHPLQDNGTVQGVLEIFSRMEEMLAEISGMDRVSLQPGAGSAAIWTNVAMVRAY 186
70607137   78 VPLGSCTMKYNPKVEEKISDV--VSGLHPLQDSETVQGILEIIYEMQLMLAEITGTDICSLQVPAGSAGELAGVLMIKKY 155
148655660 151 HRDRGDh-ERVEVLVPDSAHGTNPATAAMAGYRVVEVKSDAR-GNVDLEDLRRKLSPRTAALMLTNPNTLGLFEEHVVEV 228
111025248 167 HASRGEleQRNEVITTIQTHPCNAATAAAAGFKVITLMLDEN-GYPSLDALKAAVSNRTAALMVGNPDDMGVYNPEMKEW 245
271968916 176 HASRGEgrQRDQVITTMFSHPSNAACAKTAGYEVITLMPDEN-GYPDIEALRAAVGPRTAALMITNPEDTGIFNPRIEEF 254
146304428 152 HRDQNR--RREEMLVADSAHGTNPASAAMAGFSVIYIKSNQE-GLVDLNVLKGTISDNVAGFMLTNPNTLGLFEENIKEI 228
170290222 168 HKKRGE--ERDEIITTIFSHPSDAAAPAVKGFKVITIYPDPEtGIPDVEALKAAVSKRTAGMIVANPEDTGIFNPRIKEF 245
170291056 167 ISDLGE--RRDEMLIPETAHGSNFASAAMAGFRVVRIPPSEE-GTIDMSALKASISERTAGIMITNPNTLGIFEDRMVEI 243
226315350 184 HESRGEgeQRNEFITTHFSHPSQAATAAVKGFKIIYVPADEN-GYPDLEALKGLVSERTAAFAVANPEDTGIYNSRIKEF 262
256391230 179 HASRGEgeLRDEVITTQFSHPTNAAAPKTAGYRVITLMPDAD-GYPDIEALRAAVGPRTAALLITNPEDTGIFNPRIEEF 257
291300222 187 HASRGEs-HRDEIITTVFSHPSNAACAATAGYKVITLYPDAD-GYPDLDALKAAVGDRTAALLITNPEDTGIFNPRIEEF 264
70607137  156 HELKERf-SRDEMLVADTAHGTNPASAAMAGYKVIYIRSNKE-GLVDIDLLREVVGEKTAGFMLTNPNTLGLFEENIVEI 233
148655660 229 ARLVHQAGGLVYGDGANFNALLGIAKPGELGFDFMHYNLHKTFTTPHGG-GGPGSGAVGCTAALAPFLPAPRV-----RR 302
111025248 246 VEIVHEAGGLCFYDSANFNGTMSKIRPREIGFDACMFMLHKTFGAPKSGvGGPATGAYGCSAELAPFLPAPLV-----TF 320
271968916 255 VSLVHEAGGLACYDQANANGLLGITRAADAGFDLCHFNLHKTFSTPHMC-GGPAGGASCVSEALAPFLPGPVV-----EF 328
146304428 229 AELVHSVDGVLYYDGANLNGILGIVRPGDMGFDIVHLNLHKTFGVPHGG-GGPGAGAVCAKGKMTKYLPYPIV-----SK 302
170290222 246 CDIVHEAGGLCGYDQANANGIIGIVRAKECGFDMGFFNLHKTFSSPHGC-GGPAVGALGVRRELENFLPVPVVdydpeRK 324
170291056 244 SELIHANGGYVYYDGANLNAIMGWVKLSDIGVDVAHLNIHKTFSAPHGG-GGPGAGAVGVVDQLKDYLPVPII-----VR 317
226315350 263 TDVVHAAGGLCCYDQANANGLLGITRALEAGFDMCFFNLHKTFSVPHAC-GGPATGAIGVTAELAPFLPGPLV-----DF 336
256391230 258 VRLVHEAGGLCCYDQANANGILGITRARDAGFDLCHFNLHKTFSTPHMC-GGPAAGASAVTSALEPFLPRPTV-----EF 331
291300222 265 VAAVHEVGGLAVYDQANANGILGITRAREAGFDLCHFNLHKTFSTPHAC-GGPAAGACGVTSALEPFLPKPTV-----EH 338
70607137  234 AKLLHNVDAKLYYDGANMNGILGVVRPGDMGFDIVHLNLHKTFAVPHGG-GGPGAGAICAKGDMVDFLPYPIV-----EK 307
148655660 303 vphegeplpptergvslrpagapalpeGA---YELfa-peK-TIGRVKTFHGNFGMLVRAWTYIRSIGAVGLRRVSETAV 377
111025248 321 ---------------------------DGe-rYHLdhdrpD-SVGKIREFWGNVPVILKAYAWVRAMGAEGIAQASDISV 371
271968916 329 ---------------------------DGe-rYHLdadrpL-SVGKTRPFLGVTPNVVRAYAWVMALGAEGLREVAETAV 379
146304428 303 ge-----------------------------rYYLvk-peR-SIGKISVFNGNFGNLMRSYAYILGLGGKGVSMIGRMST 351
170290222 325 a-------------------------------YYLnydlpD-TIGKVREFYGVFPVVVRAYAWIMALGEEGLKEVARVAV 372
170291056 318 ---------------------------DGe-rYKLsydlpK-SIGKVRMFYGNVGVLIKAWAYLKMLGSEGVRESAAISV 368
226315350 337 ---------------------------DGeryFYNrd-lqN-SIGKVRSFYGVPPAVLRSYAWVRALGADGLKEVAEIAC 387
256391230 332 ---------------------------DGt-rYRLdddrpE-SIGKIRPFYGVVPNLVRAYAWIMALGGEGLRTVAETAA 382
291300222 339 ---------------------------DGt-rYWLdhdrpL-SIGKVRPFLGVAANVVRAYAWIMSLGAEGLREVAETAV 389
70607137  308 ---------------------------KNg-kYAIdy-ipKhTIGKIASFYGNIGNVVRSYVYILGLGAEGLSMIGKLST 358
148655660 378 LNANYV-QARLKHV--YPAAV-D--RT-CMHETVLQGKLA--AAPEVRTLDIAKRLIDYGFHPP-TVYFPLIVPEALMIE 447
111025248 372 LGNNYM-EKGLLAIrgVTRSHpE--STsPRLEMTRYSMQIlkEDTGVDVHDVQNRMTDFGIDAMwTSHEPWLIPEPFTPE 448
271968916 380 LNNNYL-MHRILQIpgASAHWgG-----GRLEQVRYSWQGlfEETGVHSEEIGVRAADFGVHYW-TSHHPYLVPEPFTLE 452
146304428 352 LATNYL-IAKLRGVrgLELMApH--RF-RKHEVVFSAKKLa-EETGVTAFDIAKALLDRGFYAP-TIYFPPNVEEALMIE 425
170290222 373 LNNNYVmHRILREVrgADISYpAn-KR-RIEQVRYSLKKLk-DETGVGAEDVIRRMADFGFHLW-TSHHPWIIPEPLTIE 448
170291056 369 LNANYV-RKKLMNSg-FEVPYgR--NRpCKHEFVISLAKIk-KETGVRALDFSKALIDEGLHPP-TMYFPQIVQECLMIE 442
226315350 388 LNNNYL-YHKILQIrgASAPYiQ--GR-RLEQVRYSWQQLk-EDTGVTTYDVQRRMVDFAHHYW-TSHHPYVVPEPFTLE 461
256391230 383 LNNNYL-ISKVLQIkgVSLPYaQgrR--RVEQARYSWQKLn-ADTGIHSEELGYRVADFGTHYW-TSHHPYLVPEPMTLE 457
291300222 390 LNNNYL-LAEMLKIdgVSAPYaEg-KH-RIEQVRYSWQKLh-EDTGVHSEDLGLRAADFGVHYW-TSHHPHLVAEPATLE 464
70607137  359 LATNYI-IFKLRNVkgLDLIApY--RP-RKHEVVFSAKELa-RDKGVTAFDIAKALLDRGFYAP-TIYFPPNIEESIMIE 432
148655660 448 PTETESKRTLDAFCDALLAIAEEAARDPEILKRAPTTTPVRRL-DE--VRAARQPIL----RY 503
111025248 449 AGEMYGKESLDQWIAVLAQISDEAYSNPDIVKSAPHNQAIHRL-KPgvTDDPSTRAM----TW 506
271968916 453 PTESYSQEDLDEYAAILAHVADEARRDPEYVRGAPYNQTVHKI-DQtsLDDPKQWSP----TW 510
146304428 426 PTETEPIEVLDQYANAIKDIVEKAYSNPSSITSAPQNTSVGRL-DQ--VKANHPSTMt--pTY 483
170290222 449 PTESYSKEELDEYVEALKEVVREAYEEPETVINAPHRSVIHKIeDNswFSDPKKWSI----TW 507
170291056 443 PTESDSIAELDRYVGAMIKIKEKAYERPEEIINAPKRAAITRI-DE--SFANKVLWL----SW 498
226315350 462 PTESYSMAELDEYVAALTHISQEAYENPEIVKTAPHNSTGHRV-LEsvLDDPNQWCI----TW 519
256391230 458 PTESYSQADLDEYAAILAEAAREAYEDPELVRSAPHNGPIHRM-RD--ASLEDPGTWavtwRA 517
291300222 465 PTESYSKADLDEYVAIMRQVAHEAYTEPETVRTAPHRSTIHRT-KHdtLEDPGTWAV----TW 522
70607137  433 PTETEPKEVLDSFAEALTEIAREAYNNPNNVISSPTNTAVGRI-DQ--VTANHPSTIt--pTY 490
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