Conserved Protein Domain Family
DUF4587

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pfam15248: DUF4587 
Domain of unknown function (DUF4587)
This protein family is a domain of unknown function. The precise function of this protein domain remains to be elucidated. This domain family is found in eukaryotes, and is typically between 64 and 79 amino acids in length. There are two conserved sequence motifs: QNAQ and HHH. In humans, it is found in the position, chromosome 21 open reading frame 58.
Statistics
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PSSM-Id: 464588
Aligned: 23 rows
Threshold Bit Score: 70.5221
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006636780  149 KSGSIKEDMVELMLMQNAQMHQIIMHNMMLKAIPPMAFsptgggrhpgpapnQQFsqpNQDSYLGSPIILKSE---KPRG 225 
XP_005639096  277 GPGGIKEDMVEMMLMQNAQLHQILMHSLMLRALPSSVFsp-------------------lgASQAAPLHPGLQ---RPRA 334 
EEN59041      900 R-----NDMVDMMMMQNAQMHQIVMQQMMFQHLPMKQPglqq------pqqvSMPvqvMQEPP--APVVVQAPgggGKRP 966 
XP_015217363   52 QPGHVKEDLVELMMIQNAQMHQVIMNNMTMSALNAFGYsq----------------stPQPPPEPPRYPIIVE---EEYP 112 
XP_005257862   39 QPGRVKEDLLELMMLQNAQMHQLLLSRLVAGALQPRPAsp----------cpQVYlevPQEEPEE----EEEEmdvREKG 104 
ELK12465       35 QPSRVKEDLLELMMLQTAQMHQLLLSRLVAAALNLQPAsp----------lpQVCpegQQEERG-----EEEEleaPEEG 99  
EHB07343       39 QPGRVKEDLLELMSLQNAQMHQLLLSRLVARALNPETDsp----------gvQVYlegQQEEP-------EEEvhiQEEV 101 
XP_011229722   41 RPGRVKEDLLELMLLQNAQMHQLLLSGLAAGALNPSLGsc----------hpQVYlegQQEEEEEEEVGEEEEmqaQEEG 110 
6_pfamImport    1 RKEQIREDLMELMMIQNAQMYQVIMNNIAISAVEHFGPnp----------vqDISlklPQKSPMEMQIEDNEE---SDPA 67  
XP_027830146   39 QPGRVKEDLLELMMLQNVQMNQLFLSGQVAAVLNQGLSwt-----------------nsQVSLE---IQQQEEkepQEEG 98   sheep
XP_006636780  226 SSVHHHHHY 234 
XP_005639096  335 PSVHHHHHY 343 
EEN59041      967 PSVHHHHHY 975 
XP_015217363  113 EPVYHHHYE 121 
XP_005257862  105 PLVFHHH-Y 112 
ELK12465      100 PLVLHHH-Y 107 
EHB07343      102 PLVFHHH-Y 109 
XP_011229722  111 PLVFHHH-Y 118 
6_pfamImport   68 PRIFHHH-Y 75  
XP_027830146   99 PLVFHHH-Y 106  sheep
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