Conserved Protein Domain Family
HAUS4

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pfam14735: HAUS4 
HAUS augmin-like complex subunit 4
This family includes HAUS augmin-like complex subunit 4. The HAUS augmin-like complex contributes to mitotic spindle assembly, maintenance of chromosome integrity and completion of cytokinesis.
Statistics
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PSSM-Id: 464287
Aligned: 21 rows
Threshold Bit Score: 239.47
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002111568 116 VNLGTTKDGTKLALLGVSCEHLSQLNPCKRSVQQylssVQQVLIPEIETRLRKKCENLAEYYNPNSQDDGEPMTFANITE 195
XP_003229370 120 LEVDPSLQSTQSSLLGLEPSHMLELLPPKQEMEQ----IQKRLPTELEKHLKSKCLALLSYYRPESDSANETVRVAMSGT 195
EFX86383     101 VKGDKPNTEDALRVFGV---NFKQEKVDDDVTLW--------TQAQLKNQLIEKGIVLLNEMGHDVQGNNQELLKAKLNQ 169
KJE95351     155 FGAKSARHSAGETLLGLSSADLAQDASDELAA------LNGTLVRQIEAQIQDKCSALLAFYTPVSSASGAQNSTTMAAR 228
XP_001637987 120 YLSFTPEGSDEITLLGLKQEDLVQNDSHKIKIQQs---FQQNIIPELESRLRAKCELLVNFHEPSKDYESEGLSFAKAGQ 196
EFJ08850     158 DVSEVGVSGVVNRFLGITPAWLRQTHLSKAPFAEdstgYLMLLIPEIESRLKAKCEKISSSFQ---ESDGFGSHGTKSYR 234
EDQ66480     186 ETVEPGVGGVVNRFLGITPAWLRQTHLIRVPFADdntgYQMTLIPEIEARLKAKCDRLVSAF--ETDETGVADSAGPTLR 263
ERN19654     187 DSNEAGIGGVPSRFLGVTPGFLRQTQLNQIPFNEdiseYQMSVAREIEARLKAKCEKVSDAFVME-EKDSSAISQFQSAR 265
XP_009420825 186 DIVEPGVGGVPNRFLGVTPGFLWQVQQQHPVMAMdpseYQRSLVWEIESRLKAKCEILADMFAMD-DNDSSSITQISSAR 264
EES06170     176 DAVEPGVGGVPDRFLGITSDYLYQVQQEQPAMSVdmvdYQRTLAREIEARLEAKCDALADLFAMD-ERDSSSISQISSAR 254
XP_002111568 196 LPELIERDKRR--VDDEKANLTKVAVLRRRKFWQYYQEIQKCIEILDEIIRKYRLKYQADHDTITCNWFAAKCDAMCNKL 273
XP_003229370 196 LAERLAEEKQR--LQEAKDRHQELVGLLEQQKAAYPQVLLRCVAMLKRLAREYRLGTQSELDRLNTHYLEIKCSAVFLKI 273
EFX86383     170 LPSLISSKLKA--AENLKKTMEENDQALKEQYTKYTTTLLESLQIMENLLQKHMIEIQNEQNVSQSESLEVQCDALYLKI 247
KJE95351     229 MSAFVDGVQRDqaLLQQKQDSSTNDSRPNVQMEAYFTALLQTLRTMHEMVSKHLLGSQAQFDAATSKWAAAKCEAMGLKL 308
XP_001637987 197 LPAILQKEKSL--LQEERKRLGQDRLMRDRQFRQYYQTLLQSLESLEKLITKHRLQSQVRYDKVTTDWLAAKCEAMCLKI 274
EFJ08850     235 LAERVKAAVES--NESEEAALLSDLYSADRKFSEYYNVLEQILGVLIKLVKDYKLQHQHEYDEMRKAWLCKRCETMNAKL 312
EDQ66480     264 LPERVKIAVED--IEAEEAALLEDLYAADRKFSEYYNVLEQILAVLLRLVKEFKLQHQHDYDGMRKQWLCKRCQTMNAKL 341
ERN19654     266 LPERVKLIVDK--IEREEAALREDLCSADRKFAEYYNVLEQILAVLIKLVKDLKLQHQHQYDELRKTWLCKRCETMNAKL 343
XP_009420825 265 LPERVKLIIEE--VEKEEAVLLEDLYSMDRKFAEHYNVLEQILGVLIKFVKDLKLQHQHQYDELRKTWLCKRCQTMNAKL 342
EES06170     255 LPERVKLIIEE--IEKEEAHLLEDLASMDRKFAEHYNVLEQILAVLIQFVKDKKLEHQHQFDDLKKTWLIKRCRTMNAKL 332
XP_002111568 274 SVLANHLLKDSYTNETVSALNQIKHHLVTAQAEVENELTTISESLRSYEAIGMGFDKIVLQYAEIAKSIDEKRWALSQIN 353
XP_003229370 274 RLEELSILLETYTPEKLDVHRMIRDNLRATLSREEQNLATTRKILFDYETLDSAFEELVKEYARLQGIIHNRQWMLKEFN 353
EFX86383     248 KSLHLEILCETYTKETVPALKKISKELEAKSEQTENEIRASRLRLNRYESVGHDFNCIVNEYGKLRETIKQKKWTLEKLQ 327
KJE95351     309 SVLAMQLEHDTYTPATLPALALLRDYVSTAFVESRTERDASNRMLVAYQSIGSKFTELVREYGSVLEEIENRRWALEELR 388
XP_001637987 275 RVLQNQLIRDTYTPETVAALKKIRGLLEVAKEEEERELQRAREALQAYESVGMGFEALVREYSALMIEIDNKKWALSELR 354
EFJ08850     313 RVLEHLVLRDTYTEESIAALHKIRNYLLEADDEATAGYNRAVTRLREYQGVDQYFDDIARRYHDVVKKLEGIQWTIRQVE 392
EDQ66480     342 RVLEHLLLRDTYTQESIPALHKIRQHLVEANEEATAAYNRAVTRLREYQGVDQDFDEIARRYHDLVTKLVGIQWTIREVE 421
ERN19654     344 RVLEHLLLRDTYTQDSIPALHKIRKYLMEATEEASIAYNKAVTRLREYQGVDPHFDTIARQYHDILQKLEEMQWTIRQVE 423
XP_009420825 343 SVLEHLLLRDTYTKDSVPALRKIRNYLIEATEEASIAYNKAVTRLREYQGVDPHFDTIARQYHDIVKKLEGMQWTIHQVE 422
EES06170     333 SYLEHHLLRDTYTKDTVPALHRIRKYLVEATKEASNSYNEAVSRLREYQGVDPHFDVIARQYHEIVKKLEGMQWTIHQVE 412
XP_002111568 354 E 354
XP_003229370 354 K 354
EFX86383     328 S 328
KJE95351     389 R 389
XP_001637987 355 Q 355
EFJ08850     393 M 393
EDQ66480     422 K 422
ERN19654     424 M 424
XP_009420825 423 M 423
EES06170     413 M 413
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