Conserved Protein Domain Family
SBF_like

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pfam13593: SBF_like 
SBF-like CPA transporter family (DUF4137)
These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.
Statistics
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PSSM-Id: 433336
Aligned: 39 rows
Threshold Bit Score: 196.644
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001484275  24 QWFLVLLGVFVALAHSYPEFAKqggtIKAQYSIQYGaVAVIFLISGLSMGTKDLMVNMSHWRAHFTVLSMSFLVTLAIIY 103
Q0V4P5        88 QWFLLAMAAVILLASQVQVPASrqhtKR--TVVTYLsVSVIFFINGCTLETSILLENSMRWKLHAFVQLQCYLVCSAATF 165 Parastagonospor...
XP_002145158  44 QWLIIGMGIACLLAYLFPNVAKhggiIKSQGSILYGaVGLVFLISGLSIPRSKLYTHMFNWRLHALVQVTSFLFVPAVVL 123
Q59UQ7        25 QWFFIFLGVFIALAHSYPEFAKqggtIRAEYSIGYGaVAVIFLISGLSMSTKQLLVNVANWRAHFTVLSMSFLVTSAIIY 104 Candida albican...
Q6BPS9        26 QWFFLFLGAFVAIAHSYPEFAKqggtIRAEYSIQYGaVAVIFLISGLSMSTALLRVNLLNWRAHFTVLSTSFLITSSIIY 105 Debaryomyces ha...
Q05131        23 QWFFICLAILIVIARFAPNFARdgglIKGQYSIGYGcVAWIFLQSGLGMKSRSLMANMLNWRAHATILVLSFLITSSIVY 102 Saccharomyces c...
Q6FU65        32 QWFFYVLAIFIVIARFAPNFARdgglIKGEYSIGYGaVAWIFLQSGLSMKTSRLMANMTNWRAHLTILVLSFLVTSSIVY 111 [Candida] glabrata
CAR28312      23 KWFFYILAIFILLAHFFPNFAGddgiIRGQYSIGYGaVACIFLNSGLNNKTKRLIAEISNWRAHITVILLSFFITSSIVF 102
Q6CIF6        49 QWFFIGLAIFIVLARFFPNFARsgglIRGQYSIGYGaVIVIFLQSGLSMSTKKLLVNMGNWRAHLVVLVISFLVTSSIMY 128 Kluyveromyces l...
CAR22649      27 QWFFITLAVFIVLAHFFPNFARhggtIRAEYTIGYGaVAAIFLQSGLSMKTQKLCYNLGNWRAHLSVLTISFLVTSSIMF 106
XP_001484275 104 GFACAIR-LSHDga-idEW----LLVGMIVTHACPTTVLSNVVMTKQAHGNDILTLCEVFIGNLLGAFITPALVQMYL-- 175
Q0V4P5       166 AIVSLCA-TNPNfm--dPW----LLIGFLFVGSAPTTMNSNVVMTRQAHGNTALTVVQSVIGQFLCPFLTPIILQMYL-- 236 Parastagonospor...
XP_002145158 124 AVVHLII-ATDPgrlidPA----VLAGFILTSAIPTTIASNVVMTRSAGGDDAAALVEVLIANFLGPFLTAGWTVTLMpk 198
Q59UQ7       105 GIASGIK-ASHNgq-idDW----LLIGLIVTHACPTTVSSNVVMTKQAHGNDILTLCEVFIGNVLGAFITPALLQMYM-- 176 Candida albican...
Q6BPS9       106 GIACGIK-AAND-----PSmdewLLAGMIVTHACPTTVSSNVVMTKQAHGNDVLTLLEVSVGNILGAFVTPALVQMYL-- 177 Debaryomyces ha...
Q05131       103 GFCCAVK-AAND-----PKiddwVLIGLILTATCPTTVASNVIMTTNAGGNSLLCVCEVFIGNLLGAFITPALVQMFTnr 176 Saccharomyces c...
Q6FU65       112 GICCGIK-AAND-----KNiddwVLIGLLMTAACPTTVASNVLMTTEAGGNDLLCVCEVFIGNLLGAFITPALSQLYTdr 185 [Candida] glabrata
CAR28312     103 AFCCAIKkAHDK-----NMdd-wVLIGFLLMAASPTTVASNVMMTSQAGGNDLLCTCEVFIGNILGAFVTPGIIQLFT-- 174
Q6CIF6       129 GLCCAIK-AAND-----DKiddwVLIGIIVTATCPTTVSSNVVMTTKADGNALLCLCEVFIGNVLGAFITPALVQMYT-- 200 Kluyveromyces l...
CAR22649     107 GLCSGIK-KAND-----PAiddwVLMGLIVTATCPTTVASNVVMTKKAGGNDLLCLCEVFIGNVLGAFVTPALVQMFTss 180
XP_001484275 176 ---------RGTwafgnpthqgsglseTIQQL---------YAEVMkqLGLSVFVPLFGGQVVQNIFPKQtkwt-lltFr 236
Q0V4P5       237 ---------SSGaw-----------ysKV--LihgdgyaeiYKRVFmqLGLSLFLPMFVGQVVQKLFPKQtkkvffdyN- 293 Parastagonospor...
XP_002145158 199 taefelwrsGSS---------------DMSQM---------YRDVFkqLGLSALLPLVIGQLIRWTWEKQtvyilqkfY- 253
Q59UQ7       177 ---------RGTweignps-hqtqgdsTVQEL---------YAHTMkqLGLSVFVPLFVGQVVQNIFPKQtkwc-lttFk 236 Candida albican...
Q6BPS9       178 ---------VGTwefanpt-hqssgdtTIQDL---------YREAMkqLGLSLFVPLFVGQVIQNVFPKQtkwt-lttFk 237 Debaryomyces ha...
Q05131       177 apfaygnpaTGN---------------GIGAL---------YGRVMkqVGLSVFVPLFVGQVIQNCFPKGtay--ylgF- 229 Saccharomyces c...
Q6FU65       186 apfeygnpaNGN---------------SIGSL---------YGRVMkqVGLSVFVPLTVGQIAQNMLPKPtki--yldF- 238 [Candida] glabrata
CAR28312     175 ---------DSAlfkfgn----panhsSVKDV---------YRRVLfqVGLSVFVPLATGQIIQNVLPKPtqi--ysnF- 229
Q6CIF6       201 ---------SSGpmvfgn----patdtSVQQL---------YANVMkqIGLSVFIPLFVGQVLQNVFPKQvtwf-lttFr 257 Kluyveromyces l...
CAR22649     181 slfafgnpaSGS---------------SVSHL---------YADVMkqIGLSVFVPLFVGQVLQNIFPEQvswc-lstFk 235
XP_001484275 237 LSKV----GSFMLLLIMFQSFSTAFAQKAF--ESVSHasIIFIVFFNIGIYLFFTLLCFL-WSRPYFIKvlfseeptpqh 309
Q0V4P5       294 IIKL----SSIALLTLVWQTFDQAFQSGAF--KTVKP--SNIAFIVFITMALYMIWLAIC--FSASIMW----------- 352 Parastagonospor...
XP_002145158 254 VAKF----STGCMILLVWTTFSSAFATDSLetLTTQT--VIFTVLFNVALYLFLTVVCFTlARPPQALRkttwgk----- 322
Q59UQ7       237 LNKV----GSFMLLLIMFQSFSTAFAQHAF--TSVSHasIIFLVFFNIGIYLFFTVLT---FFYSRPFWilrvfkeepne 307 Candida albican...
Q6BPS9       238 LAKV----GSFMLLLIMFQSFSTAFAQDAF--TSVSHesIIFLVFFNIGIYLFFTVMT---YFYSRPLFilryfneepne 308 Debaryomyces ha...
Q05131       230 LKKYhikiGSYMLLLIMFSSFSTAFYQDAF--TSVSHvcIIFLCFFNLGIYIFFTGL--S-YLCARPWFilklfphepie 304 Saccharomyces c...
Q6FU65       239 LKKYklkiGSYMLLLIMFSSFSTAFYQRSF--TSVPHatIIFVCFFNLGIYLFFTL--IS-YAMARPFFipilfnevpde 313 [Candida] glabrata
CAR28312     230 LKKYhlkiGAYMLLLIMFNSFSTAFKQKAF--TEVSHacIIFVCFFDLGLYLFFTGICFL-CARPYLLLllfkkkpvkge 306
Q6CIF6       258 MNKV----GSFCLLLIMFSSFSTAFYQHAF--TSVSHacIIFLCFFNVGIYLFFTLVCFV-C--ARPWFiikifdhepte 328 Kluyveromyces l...
CAR22649     236 LGKV----GSFCLLLIMWSSFSTAFHQRAF--ESVSHacIIFVVFFNIAIYLFFTG--IC-YLWARPWF----------- 295
XP_001484275 310 sr---syrfgyklltpfyYSR----------------------------RDTVSVMLCGPAKTAALGVSL--VSSQYG-S 355
Q0V4P5       353 ------------------LPK----------------------------KDVIACCYCCPAKALAMVVPL--SSVMYI-N 383 Parastagonospor...
XP_002145158 323 -------------rvfrpMPP----------------------------EEAIAVCFCGPAKTTALGIPLlyAMYDSM-D 360
Q59UQ7       308 sss-klyrysyaffrpfyYNR----------------------------KDTVAVMLCGPAKTAALGVSL--VSSQYG-S 355 Candida albican...
Q6BPS9       309 shs-kaykygykllrpfyYNR----------------------------RDTVAIMLCGPAKTAALGVSI--ISSQYG-S 356 Debaryomyces ha...
Q05131       305 gkstrlyrysynifrpfyYSK----------------------------EDAICIMFCGPAKTAALGVSL--ITSQYG-D 353 Saccharomyces c...
Q6FU65       314 sss-kfyttmykifrpfyYNK----------------------------RDTVCILFCGPAKTAALGVSL--ITSQYG-D 361 [Candida] glabrata
CAR28312     307 ssk--lyyysyglfrpfyYNK----------------------------RDTVCLLYCGPAKTAALGVSL--VTSQYG-D 353
Q6CIF6       329 hss-ktyticykifrpfyYSK----------------------------RDAIAVMLCGAAKTAALGVSL--ISSQYGdD 377 Kluyveromyces l...
CAR22649     296 ------------------LPLlfpteptqdsskayktfykilspfyctkKNAIAVMFCGAAKTAALGVSL--VTSQYG-S 354
XP_001484275 356 HSq-YLGKLLVPLVLYQAEQVMTAQILVNFMKK 387
Q0V4P5       384 TSpiEQSKLQIPAIIFQAFQVAIGGIMTIGFRR 416 Parastagonospora nodorum SN15
XP_002145158 361 LY--TKSKTSIPVLLYTTEQIFVAHFMVYVLRW 391
Q59UQ7       356 HNp-KLGIILVPLVLYQAEQVMTANVLVSFMRK 387 Candida albicans SC5314
Q6BPS9       357 KNe-NLGKLLVPLVLYQAEQVITAQVLVNFMRK 388 Debaryomyces hansenii
Q05131       354 KKe-HLGKLLVPLVLYQVEQVMTANFFVSLFKR 385 Saccharomyces cerevisiae S288C
Q6FU65       362 NKs-HLGKLLLPLVLYQSIQVLTASLLVLPLRK 393 [Candida] glabrata
CAR28312     354 EKs-NLGKMLLPLVLYQAIQVLSASFLVPLFKW 385
Q6CIF6       378 NP--KLGTLLVPLVLYQSEQVITANFMVPFMKK 408 Kluyveromyces lactis
CAR22649     355 DSp-HLGKLLVPLVLYQSEQVITANFLVSFFKK 386
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