Conserved Protein Domain Family
Smoothelin

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pfam12510: Smoothelin 
Smoothelin cytoskeleton protein
This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.
Statistics
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PSSM-Id: 463614
Aligned: 15 rows
Threshold Bit Score: 45.3821
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_021332369        383 KTEAQSEKLTSEKLRDIEDEEILDKMLDECKDFEERKMIRTAMRELRKKK 432 
XP_004063366        655 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 704 
XP_016852562        562 KEKAPRGHLSAEELSKIEEEDVLDKMLDQTTDFEERRLIRAAMRELRQRK 611 
XP_016157632        489 REVEKRSKLNVEELSKIEDEDVLDKMLDRTTDFEERRLIRNAMRELRQRK 538 
XP_008182947       1531 QSISIQNADDEVEIEEIFDLHILETMLEKAVGYDRRRRIRAQIR-VVKRQ 1579
EDW00113           3189 LRTTSISEDFDIDIEAIFELATLEQLLETVSSYELRRRIRAQIRLIKKNM 3238
FlyBase:CG34417-PQ 2591 DEDS----DLELEIEEIFDLQRLEKLLETVASYEMRRRIRAQMRLIRKNM 2636
Q16M45               11 SSSSNAPKPSIENLEQIWDEAVLKQLLESSTNYEERRKIRARLRQIMAEK 60   yellow fever mosquito
PNI97960             46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQE 95   chimpanzee
XP_016157632         77 EEQQAALTALSEQLEAITSVEELTKLLRAAGEYEERKLIRAAIRKLRAEE 126 
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