Conserved Protein Domain Family
CD99L2

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pfam12301: CD99L2 
CD99 antigen like protein 2
This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.
Statistics
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PSSM-Id: 463526
Aligned: 11 rows
Threshold Bit Score: 131.479
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ELK18130      24 FDLRDAL----KETASVKQKW----------------------DYTTTTTKRPG--------------TTraP-AKPAG- 61 
1_pfamImport   1 FDLADAL----DEVNPTTPTPkpaapgg--------gkggatkAPSKVTPKAPV--------------TT--P-VKPKPk 51 
XP_003918459  30 FNLEDAV----KETSSIKQKW----------------------NQVTTTTKRPV--------------TTraP-ANTLG- 67 
Q8BIF0        30 FNLEDAL----KETSSVKQRW----------------------DHFSTTTRRPV--------------TTraP-ANPAEr 68  house mouse
XP_005991910  30 FNLEDAL----EDPTEKPKAPvtpr--------------ptkgLLTTTTTKAPKvtqpdfslldilstTTkkPkGTKAPp 91 
2_pfamImport   1 FDLADYF----DSPVEPTSKParpt--------------arpdVVRTTTTKRPK--------------TTqaP-RKQNPg 47 
XP_015217208  51 FNLGDVF----D--MPGPTKP----------------------------PVTPKpk---------------kPs------ 75 
4_pfamImport   1 FDLSDAL----DTD---DDKP----------------------------SLTPKpp--------------kkP-DTNDN- 29 
NP_001073449  54 FDLSDAFe--sD-----PKKP----------------------------AVVPPks----------vdDKkkPas----- 83 
XP_007248173  57 LDLADVFgdddDDYKPPTRKP----------------------------PVQPV--------------QPkdP-VKPKPk 93 
XP_015206936  25 FDLADAL----DD---KPTKPptvkpnpkvpggssdfdfdfdfpakKTTTKAPKvt----------ttTTkaP-PKPKPk 86  spotted gar
ELK18130      62 ------------------------SDFDLSDAW--------------------DNPND-RFDGHRKP------------- 83 
1_pfamImport  52 pa--------------------aaDDFDLSDAL--------------------DSNNDiGIKDKNKGqgdkik------- 84 
XP_003918459  68 ------------------------NDFDLADAL--------------------DDRND-RDDGRRKP------------- 89 
Q8BIF0        69 wdhvattttrrpgttrapsnpmelDGFDLEDAL--------------------DDRND--LDGPKKPs------------ 114 house mouse
XP_005991910  92 kkn------------------tdpLDFDLSDALv-------------------DNDDGiGSKGKDNR------------- 121
2_pfamImport  48 k---------------------npLDLDLADALgdrvalgqpahatatstcqvDPQHQ-KEYGCGVGt------------ 93 
XP_015217208  76 -----------------------gDEFDLGDALggpd-------------phpTKQPAvPPKNPGKG------------- 106
4_pfamImport  30 -------------------------DLDLSDALggedp----------------ftkapPVVKPNPG------------- 55 
NP_001073449  84 -----------------------gGELDLSDAFg------------------pDTETKkPMVPPKER------------- 109
XP_007248173  94 p----------------------daDFDLSDAL--------------------DPSNDiGGKGKDTGkgdkslggggrgd 131
XP_015206936  87 q---------------------asDDLNLADAL--------------------DENNDiGGKDQNKNg------------ 113 spotted gar
ELK18130      84 -------SA-----------------RGGGFSDKDLEDVL-GGD-YKPD---KGRGDGRYGNNDd-----------SEAG 123
1_pfamImport  85 --tdndpTF-----------------QSRGFSDNDLFDVSkDET-YHPD---KGKGGRPSGSKDqld------qydENSD 135
XP_003918459  90 -------IA-----------------GGGGFSDKDLEDIVgGGE-YKPD---KGKGDGRYGSDDd-----------PGSG 130
Q8BIF0       115 -------AG-----------------EAGGWSDKDLEDIVeGGG-YKPD---KNKGGGGYGSNDd-----------PGSG 155 house mouse
XP_005991910 122 ----------------------------GDFSDDDLKDVIaGG--YTPD---KNKD----GSNDpargggnvedpsKGYD 164
2_pfamImport  94 -------GS-----------------GGNTDSQGRAMGAArGAG-HN--------------------------------- 115
XP_015217208 107 ----------------------------GSFDNDDLGYVAgEGD-YNPD---KGKSGGRSGGRaeg-------dtqGGSD 147
4_pfamImport  56 -------GS-----------------GSSGNLDDSLFNIAeGGDgYKPDenkGGGGGGGGGGRGrkvspgdssdtnPGSN 111
NP_001073449 110 -------ET-----------------GGRSFDDNDLIDVSeRGG-YKPD---GGGSRGRGGAPssd-------dqsGGAE 154
XP_007248173 132 grpnirgGN-----------------GGGTFTDDDLFDVGnDNS-YKPD---KGKGGRGSASTDlds------ndnGDYD 184
XP_015206936 114 -------DKgvvpgsrgddgptggdkKGGTFTDEDLEDISkGGG-YSPD---KKPDRGRGSASSdd---------tNY-D 172 spotted gar
ELK18130     124 MSPE--TGTIAGVASALAMALIGAVSSYISYQQKKFCFRIQQGLNADYVKGENLEAVVCEEP 183
1_pfamImport 136 TTAE--VGTIAGIASAVAMALVGAVSSYISYQKKKLCFGLQQSLNADMVKTENPEAVVATEP 195
XP_003918459 131 TVAE--TGTIAGVVSALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP 190
Q8BIF0       156 ISTE--TGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP 215 house mouse
XP_005991910 165 NTAE--TGTIAGIVSALAMALVGAVTSYISYQQKKFCFSIQQSLNAEYVKGENMEAGIAEEP 224
2_pfamImport 116 -RVE--TGTIAGIASALAMALVGAVSSYISYQQKKFCFSIQQGLNAEYVKGENMEAVVSEEP 174
XP_015217208 148 QPQAegSGKIAGIVSAVGVALLGAASSYFAYQKKKLCFKISGG-DPES--GNKTQSGTQSEP 206
4_pfamImport 112 EGQS--SGSIAGIVGAVGMALLGAASSYFAYQKKKLCFRGSG--NQESVNMEA-QNKAHLEP 168
NP_001073449 155 QPQG---GALAAIISSVGVAVLGAASSYFAYQKKKLCFKVQGGEDPESGKSHG------TNS 207
XP_007248173 185 TMAE--TGTIAGIVSAVGMALVGAISGYISYQKKKLCFSIQQSLNTDMVKAENPEVVVAQEP 244
XP_015206936 173 STAE--TGTIAGIASALAMALIGAVSSYISYQQKKFCFSIQEGLNAEYVKGDTLEAVVAQEP 232 spotted gar
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