2GOX,2NOJ


Conserved Protein Domain Family
efb-c

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pfam12199: efb-c 
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Extracellular fibrinogen binding protein C terminal
This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.
Statistics
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PSSM-Id: 289007
Aligned: 4 rows
Threshold Bit Score: 70.8495
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GOX_B   1 TDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR 65 
Q2FZC2  45 TNFKKQVNKKVVDAQKAVNFFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK 109 Staphylococcus aureus subsp. aureus ...
Q2FZB8 101 TDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK 165 Staphylococcus aureus subsp. aureus ...
2NOJ_B  16 TNFKKQVNKKVVDAQKAVELFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK 80 
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