Conserved Protein Domain Family
BCL9
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pfam11502: BCL9 
B-cell lymphoma 9 protein
The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. BCL9 associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes.
Links
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Statistics
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PSSM-Id: 431912
Aligned: 11 rows
Threshold Bit Score: 37.7617
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EFA11241      298 NLTPQQRQHREEQLATIRKMQQMLFPENQAMDGQPPP 334 
XP_003240876  569 NLTPQQRQHREEQQATLRKLQLVLFPENSNSGGGPSQ 605 
XP_002072634  551 NLTPQQRQHREEQLAKLKKMNQFLFPEHDSGVGGQMI 587 
EDX15203      446 NLTPQQRQHREEQLAKIKKMNQFLFPENENSVGANVS 482 
EFN68427      313 NLTPRQRQHREVQLATLRKMQLMLFKDEQSGNALADT 349 
EDO63471      472 NLTPQQRQHREQQLATLRQMQKMFFPE-QRGMGMDPH 507 
XP_005171041  502 GLSQEQLEHRERSLQTLRDIQRMLFPDDKDMAAMGQG 538 
XP_003212777  385 GLSKEQLEHRERSLQTLRDIERLLLRSGEAEPFMKSS 421 
XP_023817397  350 GLSKEQLEHRERSLQTLRDIERLFLRSGTAGGPGDAG 386 
XP_005159295  373 GLSKEQLEHRERSLQTLRDIERLLLRSGTGVAQEDPR 409 
XP_017278149  468 GLSQEQLEHRQRSLQTLRDIQRMLFPDDRDAPPPGPP 504
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