Conserved Protein Domain Family
PP28

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pfam10252: PP28 
Casein kinase substrate phosphoprotein PP28
This domain is a region of 70 residues conserved in proteins from plants to humans and contains a serine/arginine rich motif. In rats the full protein is a casein kinase substrate, and this region contains phosphorylation sites for both cAMP-dependent protein kinase and casein kinase II.
Statistics
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PSSM-Id: 463025
Aligned: 87 rows
Threshold Bit Score: 42.9569
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDW03834      86 NPNRVyKKITENLAQiKidddvatsggdddavagaegggyfkANARKpEMCRKrvnfELLKQKKKKSVERYEKLQPAENT 165
Q5KJ14       125 APVPKgKAKVAKKAEpV-------------------------------QMSRK----EREAAEKKAAEQRYQNLHAQGKT 169 Cryptococcus ne...
CCA66442      92 NPNRL-PVKNLKISD-V--------------------------GAPR-ELSRR----EREAKEAAEAKERYWKLHQAGKT 138
CCG82558      99 NPNRA-AQKSMKASD-L--------------------------KSDTyEPSRK----EREAAEKKAAQEKYWKLHQAGKT 146
XP_003323286 121 NSNRV-VKKSVKINE-I-------------------------SNLDTgTLNRK----EREAAEKKAAQERYWKLHQAGKT 169
XP_007411344 115 NSNRT-QKKVVKVTE-I-------------------------EKVASgPMNRK----EREAAEKKAAQERYWKLHQAGKT 163
ESK93334     121 NPNHV--KKKMNIKD-L--------------------------NAPR-ELSRR----EREAKEKQEAKERYWKLHQQGKT 166
CEL57122     122 NPNRV-PMKNLSISD-V--------------------------GAPR-ELSRR----EREAKEKKEAEDRYWKLHVQGKT 168
EKM75418     114 NPNHV--QKKLTISD-L--------------------------NEPR-QLTRR----EREQKEKKEADERYWKLHVQGKT 159
EMD35147     112 NPNIT-VGKKMNIAD-L--------------------------GAPR-ELTRR----EREEKEKKDAKERYWKLHEQGKT 158
EDW03834     166 IKEKSDLARLALIRQQREEAAAKREAVKR 194
Q5KJ14       170 MEAKTDLARLQEVRARREAAAAQRKAEAE 198 Cryptococcus neoformans
CCA66442     139 DQAKADMARLRKIREEREAAAAARKAEAE 167
CCG82558     147 DQAKADLARLKVIREKREAAAKAREAEKA 175
XP_003323286 170 DEAKVDLARLAKIRQEREQAAAFRKAEAE 198
XP_007411344 164 DEAKVDLARLAKIREQREHAAAVRKAEAE 192
ESK93334     167 EQAKSDLARLAKIRAEREAAQAKRKAESE 195
CEL57122     169 DKAKSDLARLAKIRAEREVAAARRKQEAE 197
EKM75418     160 DQAKSDLGRLAKIRAEREAAAAKRQAEAE 188
EMD35147     159 DEAKADLARLAKIRAEREAAQARRKAETE 187
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