1XNI


Conserved Protein Domain Family
53-BP1_Tudor

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pfam09038: 53-BP1_Tudor 
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Tumour suppressor p53-binding protein-1 Tudor
Members of this family consist of ten beta-strands and a carboxy-terminal alpha-helix. The amino-terminal five beta-strands and the C-terminal five beta-strands adopt folds that are identical to each other. This domain is essential for the recruitment of proteins to double stranded breaks in DNA, which is mediated by interaction with methylated Lys 79 of histone H3.
Statistics
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PSSM-Id: 430382
Aligned: 2 rows
Threshold Bit Score: 249.946
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XNI_B          1 SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKE 80   human
XP_011608125 1125 SFVGLRVVAKWSSNGYFYSGRIMKDAGEGRFRLRFDDGYECEVAGKDILLCDPIPLETEVTALLEDEYFSIGVVRGHKTE 1204
1XNI_B         81 SGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGL 118  human
XP_011608125 1205 GQELFYSVEKDGQRQWYNRKAVILSLEQGNKLREQHSL 1242
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