5CL4,3ZBO


Conserved Protein Domain Family
DNA_alkylation

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pfam08713: DNA_alkylation 
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DNA alkylation repair enzyme
Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.
Statistics
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PSSM-Id: 378033
Aligned: 89 rows
Threshold Bit Score: 86.9152
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5CL4_A         12 LQEHFTAHQNPEKAEPMARYMK-NHFLFLGIQTPERRQLLKDiIQIHTLPdq--kdFqiiIRELWDLPEREFQAAALDIM 88 
EAQ05680       22 ALAALGS--DPAKAAEMARHHK-VDRAYLGVTPPAIEAVAKGwREALDLEar--laL---AAALWASDVHEGQIAAAKLL 93 
jgi:Pden_2256   3 ELDELKALGDAGKAAEMAAYHK-APREYLGVVVPVIDDLARGwRAELDVPgr--vdL---AARLWDSDVHEARIAAAKLL 76 
Q5Y0L2         32 LQELLKSYVDRDATKNYQRIIP-DTGKFFGVPLPILRVVAAEiGKFIREEpteaklL---LETIWNEGSFEARQIAGKCM 107 uncultured arc...
EDM80263        8 VMAKLEAEGNLHARNTYGRHGA--TGPMFGVRTSKLSRMARDyGPDq--------eL---ADALWATGNVDARLLAAKVA 74 
Q8FTG7         57 TLRTLEALADPKILAVNERHGDd-----HAVNLTKLRAVAKDlKKNq--------eL---ALRLWDSGDTAGRLVSLLIC 120 Corynebacteriu...
Q6HGG6         22 VMQELEALGKERTKKIYISNGA--HEPVFGVATGAMKPIAKKiKVNq--------eL---AEELYATGNYDAMYFAGIIA 88  [Bacillus thur...
WP_014091737    7 LDAELSALQNPNTIKIFRNHGCpETLELYGLKIGDLKKIIRReKLNKNHE------L---ALQLIESNNSDLIYLGLLAV 77  Listeria ivanovii
A0AF07          7 LNTELQSLENQNTIKIFRNHGCpESLELYGLKIGDLKKIIRReKLNKNHK------L---AVELIESNNSDLIYLGLLAI 77  Listeria welsh...
jgi:Sfum_2664   6 IMEHLGRMGNPEDLDGMERFGI-PRAGNLGVRVPELRRLARRiGIDs--------gL---AEALWNLGYRETRLLASMVQ 73 
5CL4_A         89 QKYK--KHINETHIPFLEELIVTKSWWDSVDSIVPTFLGDIFLKHp-----eLIsAYIPKWIASDNIWLQRAAILFQLKY 161
EAQ05680       94 TQARirPDDSAA-WDMITAWVPACDGAAIADQVAIAGQKRLVADp------aRF-DVLADWVASDHLWTKAAVLGFTLPW 165
jgi:Pden_2256  77 TQARirPDEA-A-WRLIAGWVPQFDTWAIADHAMKAGERRLLAQp------aRL-DEVELWLEHPSLWVRRAALVGTLPW 147
Q5Y0L2        108 EKFG--PKNSETCLNFVSSVLPDLDNWSVCDNLAMFGVEPIVYSNpe----lVL-PLSEKWIKSENKWTRRFGVVTLRGY 180 uncultured arc...
EDM80263       75 ------DHEAIT-AARLEAWVEDCDWYMLVDGFVADCAARTr---------hVR-ALAEQWRGSEAEYRGRAGWSLVAHL 137
Q8FTG7        121 ------RPKEFS-TDQLDSMIREARTPKVTDWLINYVVKKHp---------dWD-ELRRHWLADPDDAVRAAGWSLNTFA 183 Corynebacteriu...
Q6HGG6         89 DP----KAMSES----------DFNRW--IDGAYFYMLSDYVVAVtlsesniAQ-DVADKWIASGDELKMSAGWSCYCWL 151 [Bacillus thur...
WP_014091737   78 NP----KKVAVS----------QIEKWNIAFRDAWTMLTFGLASVvsk-rddAL-TFARKWIKSDADLTKSMGWQIFTEH 141 Listeria ivanovii
A0AF07         78 DP----NKVTSE----------QIKKWNIAFRETWTMLTSGLSSLvsk-redAL-LFAKEWIKSDYDLTKSMGWQIFSEH 141 Listeria welsh...
jgi:Sfum_2664  74 ------DPKTLE-EGRLEAWLKDFDSWEITDGTILNCFWKHp---------aAH-RKALEWSRREREFEKRAGFVMMAIL 136
5CL4_A        162 KQK--------MDEELLFWIIGQLHSSKEFFIQKAIGWVLREYAKTNPDVVWEYVQN--------N--E-LAPLSKREAI 222
EAQ05680      166 TKQthpkpadlALRDRALDWAGTLAGDPHKVIQTALVSWLASLAKHDPASASGFVDR--------HgaA-MKSYALKSAR 236
jgi:Pden_2256 148 THIrnpkpqdlERRERVLSWLVRLADDREWFVQKAIGWWLRELSKHDPQRVRDWLAA--------DgaR-LKPFARREAG 218
Q5Y0L2        181 KRI--------QTTNEVFEILDLVMEDEEKDIKKAVSWVLREITKKNPDDVAEFLTRwa----kaNpdK-DARWIIKEGM 247 uncultured arc...
EDM80263      138 ARQgev---ggALFETCLDEIAAGIHAAANRKREAMNAALIAIGGHRAGLRERAVAVaeav-gavEvdHgETGMVTPDAR 213
Q8FTG7        184 ITAap----sqIDPDSLLKSIESDMADASPRLQWNMNETLANIGIEHPDLRQRAIDIgerlgvlrDypT-PPNCTSPFAP 258 Corynebacteriu...
Q6HGG6        152 LGNrkdnefseSKISDMLEMVKDTIHHSPERTKSAMNNFLNTVAISYVPLHEKAVETakev-givEvkRnNKKSSLLHAT 230 [Bacillus thur...
WP_014091737  142 IATl-------PEAEELLELAKESLQSETNRTRYSMNSYIIACGIYKEELYTKALEAaesi-gkvYvdLgKTACKVPDAI 213 Listeria ivanovii
A0AF07        142 IPDl-------DQAEDLLLLIKETLQSETNRTRYSMNGFIIACGIYKDDLYDNAVEVaksv-gkvHvnLgKTACKVPDAV 213 Listeria welsh...
jgi:Sfum_2664 137 AVKdkg--lpdFEFNPFLVAVAREAGDERNFVKKAISWALRQIGKRNALLNKAAIGVgee--lkkSenR-AARWIASDAL 211
5CL4_A        223 KHI 225
EAQ05680      237 HRL 239
jgi:Pden_2256 219 RWL 221
Q5Y0L2        248 TKL 250 uncultured archaeon GZfos12E1
EDM80263      214 AYL 216
Q8FTG7        259 IWI 261 Corynebacterium efficiens
Q6HGG6        231 ESI 233 [Bacillus thuringiensis] serovar konkukian
WP_014091737  214 TYI 216 Listeria ivanovii
A0AF07        214 SYI 216 Listeria welshimeri serovar 6b str. SLCC5334
jgi:Sfum_2664 212 REL 214
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