5QST


Conserved Protein Domain Family
STAG
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pfam08514: STAG 
STAG domain
STAG domain proteins are subunits of cohesin complex - a protein complex required for sister chromatid cohesion in eukaryotes. The STAG domain is present in Schizosaccharomyces pombe mitotic cohesin Psc3, and the meiosis specific cohesin Rec11. Many organizms express a meiosis-specific STAG protein, for example, mice and humans have a meiosis specific variant called STAG3, although budding yeast does not have a meiosis specific version.
Links
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Statistics
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PSSM-Id: 462502
Aligned: 102 rows
Threshold Bit Score: 76.8271
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5QST_A         79 GDYPLTMPGPQWKKFRSNFCEFIGVLIRQC-QYSIIY--DEYMMDTVISLLTGLS-----DSQVRAFRHTSTLAAMKLMT 150 
KJE90216      350 GEYPLAASGTEFRRFKSGFPDFLHRIFSRC-TGDLLH--DQALIDVAITWLSALS-----TAHIRAFRHTATAACLEICS 421 
Q54QR0        107 QHYPLGNKRS--KILIENFNQFWSELVEKC-KKSIIF--DNYLLDMVALWLHELS-----FAAKRGIRHVATQAAIQITS 176  Dictyostelium...
EGG21177      259 STFPIGGKKA--KGLHNLFIEFFRAIYAKC-QTSIFFehEAYLLNMVIPWTNKLG-----MFKVRGVRYASTLAAIQLAN 330 
XP_001415613  151 GDDPLAKRSRDFKGFRENFLDFIDKCIRDAsEGGELY--DGTLFATLAEIVSTCA-----GSKARPLRMAATMMGLQMIS 223 
Q01FV9        149 GEDPLAKRSQDFKGFRENFMEFTDKLIKDTaEGEELF--DGRLYASVAEIVTTCA-----QCKARPMRAAATMMGLQIIT 221  Ostreococcus ...
XP_002978204   72 VEDFVTSKQKDLRGFKDNLTLFWDTFVLEC-QNGPLF--DEQLMEMCINFVTALSwqvkkNTPPRHFRHVSTLIGLQLAT 148 
XP_009408240  158 VEDHVNSKQKELKSFKENLASFWDNLVLEC-QNGPLF--DKVLFEKCMDFVIALS-----CTPPRVYRQVASLVGLQLVT 229 
Q60D95        140 VEDNYNTKQKDLKNFKENLVSFWDTLVHEC-QNGPLF--DGSLFQKIKDYVVALS-----CTPPRVYRQVASLVGLQLVT 211  Japanese rice
XP_003521521  150 VEDYQNSKKKEIKNFKENLESFWDNLVREC-QHGPLF--DQVLFDKCMDYIIALS-----CTPPRVYRQVASLMGLSLVT 221 

5QST_A        151 ALVNVALNLSIHQDNTQRQYEAERNKmiGK-RAN----ERLELLLQK 192 
KJE90216      422 ALVTAVKTVHAALDNSQRQLETERSK--RG--ANsssaAQLERRIEN 464 
Q54QR0        177 SLISICNDLRKDLNVTTRQLAGETK-------NS----SRQKQLKDN 212  Dictyostelium discoideum AX4
EGG21177      331 TLIKLWAQIKQDLTLTRQRLAKENK-------ES----ESFEQYKKN 366 
XP_001415613  224 SLITVVNNLQKARDLKQNQVDIELKK--KK-SGG----EVVKSLKRQ 263 
Q01FV9        222 SLISVVNSLQSTRDLKQNQLDNETKK--KNgVDA----EIVKSLKRS 262  Ostreococcus tauri
XP_002978204  149 SFVTVAKTLSQSRETKQRQLIAEEKK--KR-KDA----ARIESLNKV 188 
XP_009408240  230 SFINIAKILSGQRETTQRQLNAEKKK---Q-NEG----PRLESLNKR 268 
Q60D95        212 SLISVAKTLSGQRETTQRQLNAEKKK---Q-TDG----PIVESLNKK 250  Japanese rice
XP_003521521  222 SYITIANMLRAQRETTQRQLEAEKKK---R-TEG----PRVDSLKKR 260
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