Conserved Protein Domain Family
Ureide_permease

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pfam07168: Ureide_permease 
Ureide permease
Heterocyclic nitrogen compounds may serve as nitrogen sources or nitrogen transport compounds in plants that are not able to fix nitrogen. This family represents ureide permease, a transporter of a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine; it has 10 putative transmembrane domains with a large cytosolic central domain containing a 'Walker A' motif. Ureide permease is likely to transport other purine degradation products when nitrogen sources are low. Transport is dependent on glucose and a proton gradient. The family is found in bacteria, plants and yeast. These transporters are constituted of two sets of 5xTMs.
Statistics
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PSSM-Id: 462111
Aligned: 13 rows
Threshold Bit Score: 554.706
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EES17067      41 TFLDFSVTNFLAAVLVALTFGQIGPdtpETPNFLTQLAQvqNNWPSVLFAMAGGVTLSLGTLATQYGWAFVGLSVTEVMA 120
XP_003576090  41 AYLDYSVSNLLAAVLIALTFGQLGD---GRPNFFTQLRQaqDDWPSVLFALGGGAALSVGNLCTQYGWAYVGLSLTEVIV 117
Q2QQ90        41 TYLDYSITNFLAALLVAFTFGQIGAdtpETPNFLTQLTQmqDNWPSILFAMSGGIFNGLGTLATQYGWAFVGLSVTEVMA 120 Japanese rice
XP_014757277  41 TFLDFSLTNFLAAVLVGLTFGQIGPdspDTPNFLTQLARpqDTWPSILFAMAGGVVISLGTLATQYGWAYVGLSVTEVMA 120
EFJ25221      41 TYIDYAISTFAVAVIFALTLGQIGDsdpSAPNFIQQLSQ--DNLPCVLIAMAGGIALCLGNICMQYSLVFVGISITEVIS 118
EFJ12276      41 TYLDYCITNYIAAIVIALTLGQIGEsstQTPNFLEQLKQ--DNWPSVGFAMAGGIVLCLGNLSLQYALAYVGLSVAEVIS 118
XP_002311338  41 TYLDYSITNLLAAVIIALTFGEIGS---GRPNFTTQLSQ--DNWPSIMFAMAGGVVLSLGNLSTQYAWAFVGLSVTEVIT 115
XP_002875219  41 TYLDYTLTNLLAAVIIALTLGEIGp---SRPNFFTQLSQ--DNWQSVMFAMAGGIVLSLGNLATQYAWAYVGLSVTEVIA 115
EFH51470      41 TYLDYSITNLLAAIIIAFTFGQIGStkpDSPNFITQLAQ--DNWPSVMFAMAGGIVLSLGNLATQYAWALVGLSVTEVVT 118
KRH75038      68 TYLDYSITNFLSALLIAFTLGGIGKgthDQPNFLVQLAQ--DNWPSVLFAMGGGLFLSLGNLSSQYAFAFVGLSVTEVIT 145
EFH51469      41 TLLDFATANLLAAIVIAFSLGEIGKstfRKPDFTTQLPQ--DNWPSVLLAVAGGVLLSIGNLATQYAFAFVGLSVTEVIT 118
Q93Z75        49 TYLDYSITNFLAAIFIAFVFGGIGEsthEAPSFITQLTQiqDNWPSVLFAMAGGVGLSIGNLATQYSLAFVGLSVTEVTA 128 thale cress
XP_009392472  41 TYLDYSITNLLAAVIIALTLGQIGDstpEMPNFITQLGQ--DNWPSTLFAMAGGIVLSLGNLSTQYAWAYVGLSVTEVIS 118 wild Malaysian ...
EES17067     121 SSLKVVIGTTLNYFLDGRINKAEILFPGVGCFLIAAILGSLVHASNAADNQEKLANSLAKYSKNTRK---NTADDEDLTK 197
XP_003576090 118 SSLTVVVGTTLNYFLDNKINSAAILFPGVACFLAAATLACALHSSNKADDKKKLSASPNSYSFCTNG---GLTLGEQVSI 194
Q2QQ90       121 SSLKVVIGTTLNYFLDGRINKAEILFPGVGCFLIAACLGSLVHSSNAADNQEKLSSAMVNHSNTNGD---TENEELTKHL 197 Japanese rice
XP_014757277 121 SSLKVVIGTTLNYFLDGRINKAEILFPGVGCFLVAACLGSLVHSSNAADNQEKLSRSRHATTGNTAN---EELTKNLLDK 197
EFJ25221     119 ASLAVIFGTTANYYLDNCLNSARVLFPGVGCFVIAVLLGSFCHASNANDRTARLGPSNPRCEAEQDL---HTNLLKSSLV 195
EFJ12276     119 CSITVVAGTTMNYFLDDRINRAEILFPGVACFLIAVFLGSALHSSNTKDNRAKLAAAELLNSNDGSG---SSYKRLDVEM 195
XP_002311338 116 SSITVVIGTTLNYFLDDKINKAEILFPGVGCFLIAVCLGSAVHSSNAADNRAKLKGLTSDNKNVTETvgsSAYSNEASQN 195
XP_002875219 116 ASITVVIGTTLNYFLDDRINRAEVLFPGVACFLIAVCFGSAVHKSNAADNKSKFQDFKSLETASSF-------------- 181
EFH51470     119 SSITVVIGSTLNYFLDDKINKAEILFPGVACFLIAVCLGSAVHRSNADDNKAKLRDFEMAKQEASGP---STEIGTNSSK 195
KRH75038     146 ASITVVIGTTLNYFLDDKINKAEILFPGVGCFLIAVFLGSAVHSSNAADNKAKLSNFTGDYKDGDIS---SSKEGDIVKS 222
EFH51469     119 ASITVVIGTTLNYFLDDKINKAEILFPGVGCFLIAVFLGAAVHASNAADVKAKLKSLPSEYKAETKD---FYSSTKNVED 195
Q93Z75       129 ASITVVVGTTVNYFLDNGLNRADILFSGVGCFMVAVCLGSAVHSSNSADIKAKLGKLSGDCETVTPE---ECQRLFGV-- 203 thale cress
XP_009392472 119 SSITVVIGTTLNYFLDDRINRAEILFPGAACFLVAVCLGSAVHSSNAADNTKKLSGSSSNSTSQTCN---SRDQEVSK-- 193 wild Malaysian ...
EES17067     198 -HlLNkei--pkDPEAAKPdaadqaTEAPEKVEAGTAEFLVNLEEKRSIKVLGSHTLLGLGIVVFAGVFYALFAPALNLS 274
XP_003576090 195 -TePLr------DTENGDSp-----VTDATRAKPGSKEYLIELEQRRSIKVLESNKFIGIAIVLFAGFLMSLFSPAFNLA 262
Q2QQ90       198 -L--Eieq--pkDCEEQEPeva-paAQAVEKLEAGTADFLVDLEGKRSIKVLGSNTFLGLGIVTFAGVSYSLFSPAFNLA 271 Japanese rice
XP_014757277 198 eEkPK-------DCEEAKPd----ePKAVEKIEAGTADFLIHLEDKRSIKVLGSHTLVGLGIVTFAGICYSLFSPAFNLA 266
EFJ25221     196 ------------DLIATE----------------TSSSFM-DLEEQRAVKVRDSSVMFGLVLAFITGMCYGFFSPLFNIA 246
EFJ12276     196 -AaVEtkn--qpEEENGT--------TKTVKAQAGTAEFLDQLEHKRAIKNTTSNTILGLGIIFFAGACFSLFSPAFNVA 264
XP_002311338 196 -KgVK-------DMENGS--------STPERAKAGTADFLIELENRRSIKVFGRSTLIGLSITFFAGFCFSLFSPAFNLA 259
XP_002875219 182 ------------EMETVSAn----nGLAKGKAKEGTAAFLIELEKQRAIKVFGKSTIIGLAITFFAGICFSLFSPAFNLA 245
EFH51470     196 ------------DLETNVT------DETSTKPKEGTARFLIELENKRAIKVFGKRKIIGLAITFFAGLCFSLFSPAFNLA 257
KRH75038     223 -K----------DLESGS--------SSADNVEAGTAVFLVELEEKRAIKVFGKSTLIGLALTFFAGLCFSMFSPAFNIA 283
EFH51469     196 -NpEKek----nDVESQE--------KQAGKAKAGTAGFFVELENKRAIKVFGKSIMIGLFITLFAGTCLSLFSPAFNLA 262
Q93Z75       204 ---EE-------EEEEEK---------EMENVKEGSAAFLIALENKRAIKVLGKSMVVGLGITFFAGLSFSLFSPLFNLA 264 thale cress
XP_009392472 194 ---NLpdkdeprDLEDGGLvs--gsNINSEKAKVGTAEFLIQLENKRSIKVIGSNTFLGLSIVFFAGICFSLFSPAFNLA 268 wild Malaysian ...
EES17067     275 TNDQWHALPAGVPHLVVYTAYFYFSLACLAVSAALNVWLLYRPImAGVPASStVSAYLRDGGe-GRAPAMLAGMVCGLGN 353
XP_003576090 263 TNDQWHTLKDGVPHLMVYTAYFYFSISSFVIGVGINIWFLYCPI-ADVEKSS-FKAYLKDWK--GRQWALLAGLLCGFGN 338
Q2QQ90       272 TNDQWHTLGEGVPHMVVYTAFFYFSLACFAIGIALNIWFLYHPM-VGVPRSS-LTAYLKDWK--GRDLALVAGMVCGLGN 347 Japanese rice
XP_014757277 267 TNDQFHLLPGTAPHLGIYAAYFHFSLSCFAVGVGLNLWFLYRPM-AGVPQSS-LRAYIHDPDtgGRALALLAGMVCGLGN 344
EFJ25221     247 TNDQFHLLNPQVPHLVIYTSFFYFSTAFLVLGVLINVYLLYYPV-LGLPKSS-LSAYLSDWK--GRELAILAGLVCGFGN 322
EFJ12276     265 TNDQWHTLKPGVPRLVVYTAFFYFSTSFFVLALFLSLVLLYRPA-VGLPKSS-LTAYVADWN--GRPWALLAGLLCGFGN 340
XP_002311338 260 TNDQWHTLKKGVPKLVVYTAFFWFSVSCFVLAIILNVTFLYRPV-LNLPRSS-LKAYVNDWN--GRGWAFLAGLLCGFGN 335
XP_002875219 246 TNDQWHTLEHGVPKLNVYTAFFYFSISAFVVALILNIRFLYWPI-LGLPRSS-FKDYLNDWN--GRGWSFLAGFLCGFGN 321
EFH51470     258 TNDQWHRLKQGVPKLVLYTAFFYFSVSCFIIALILNIGFLYHPV-LGLPKSS-FKAYLNDWN--GRYWAFLAGFLCGFGN 333
KRH75038     284 TNDQWNTLKKGVPHLTVYTAFFYFSISCFVIAMILNITFLYHPV-LNLPKSS-FKAYLADSD--GRVWALLAGLLCGFGN 359
EFH51469     263 TNDQWSTLPKGVPKLVVYTAFFYFSIAGFLIALILNIIFLYRPM-VALARSS-LKKYIYDSK--GRGWAVFAGFLCGFGN 338
Q93Z75       265 TNDQWHTLKQGVPKLIVYTAFFYFSLSCFVIAVALNISFLYKPV-LDSPRSS-FREYLSDWN--GRGWALAAGLLCGFGN 340 thale cress
XP_009392472 269 TNDQWHTLNQGVPHLVVYTAFFYFSSSCFIVGIGLNIYFLYKPV-LGLPRSS-FTAYLKDWK--GRHWALLAGLLCGFGN 344 wild Malaysian ...
EES17067     354 AFTFMAGQAAGYAAADSVQALPLVSTFWGVVLFGEYRRSSRRTYTLLASMLLMFTVAMVLLMAS 417
XP_003576090 339 GLEFMGGQAAGYAAADAVEALPLVSTFWAILLLKEYWRASKKTYILLVSMLFTFAAAVALLMGS 402
Q2QQ90       348 AFQFMAGQAAGYAAADAVQALPLVSTVWGIVLFGEYRRSSRRTYTLLGSMLFMFVVAMVILMAS 411 Japanese rice
XP_014757277 345 AFTFMAGQAAGYAAADAVQALPLVSTFWGVVLFGEYRRSSRRTYVLLGSMLFMFVVAMVVLMAS 408
EFJ25221     323 GFQFMGGQAAGYAAADAVQALPLVGTLWGVLLFGEYRGSSHRTLALLVSMLVMFSVAVALLIAS 386
EFJ12276     341 GLQFMGGQAAGYAAADAVQAMPLVSTLWGVLFFGEYIRSSRRTYMLLAAMLTMFCIAVAVLMAS 404
XP_002311338 336 GLQFMGGQAAGYAAADAVQALPLVSTFWGILLFGEYRKSSRRTYILLVNMLFMFIAAVGILMAS 399
XP_002875219 322 GLQFMGGQAAGYAAADAVQALPLVSTFWGILLFGEYRRSSRKTYTFLISMLLMFIVAVAVLMAS 385
EFH51470     334 GLQFMGGQAAGYAAADSVQALPLVSTFWGVVLFGEYRRSSRKTYLLLFSMLFMFISAVAVLMAS 397
KRH75038     360 GLQFMGGQAAGYAAADAVQALPLVSTFWGVILFGEYRKSSRRTYILLGSMLFMFIVAVAVLMAS 423
EFH51469     339 GLQFMGGQAAGYAAADSVQALPLVSTFWGIVLLGEYRRSSKRTYALLVSMLAMFVAAVAILMAS 402
Q93Z75       341 GLQFMGGQAAGYAASDAVQALPLVSTFWGIYLFGEYRRSSTRTYALLVGMLVMFTVAVGLLMAS 404 thale cress
XP_009392472 345 GFQFMGGQAAGYAAADSVQALPLVSTFWGIVLFGEYRRSSRRTYVLLVSMLFMFVVAVGVLMAS 408 wild Malaysian banana
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