Conserved Protein Domain Family
TMEM_230_134

?
pfam05915: TMEM_230_134 
Transmembrane proteins 230/134
This family consists of the eukaryotic transmembrane proteins 230 and 134 (TMEM230 and 134). TMEM134 function is unknown, but it has been shown to interact with E virus ORF2. TMEM 230 is involved in trafficking and recycling of synaptic vesicles.
Statistics
?
PSSM-Id: 399128
Aligned: 9 rows
Threshold Bit Score: 95.9673
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_001378766  57 YQ---NLEN-DEDAARIPsdpdgvlkl-rdpgrsstqSSQ----------WSFSTISNGTQRSYrafcsWTQHPLIQKNR 121
XP_003313227  57 YQ---NLEN-DEDGAQASpepdggvgt-rdssrtsirSSQ----------WSFSTISSSTQRSYntccsWTQHPLIQKNR 121
Q7T382        68 YQ---NLENeDALGGTVNssfnnffki-sdpatlsycSSQ----------WSFSTLSSVTQLSAhc-cgWTSHPLVKKNR 132 zebrafish
Q7JNC1        44 HE---AISMeHDDAPYGN-------------------GGV----------YPGSSPPFTPSRPQenkstGLCSPQLKSNI 91  Caenorhabditis ...
XP_002877160   9 YA---QLPGdEDDEGYGN-------------------GVGgrrdfdprfdYTPKAFDRVP-------------------W 47 
XP_015617548  41 YA---PLPTeDRDDSNltddv------------------------dlrftYTPKSLRKIP-------------------W 74 
ETN66617      74 LKytdDTTSrDSDSLI----------------------------------QEYGHLSSSDTYTY-----CWRHPKVRENW 114
EFX88775      78 gimqddtaskDSDSLIHE-------------------SYQ----------YSPSYFDPDRI--------WWKHPRVKENW 120
XP_006013320  62 YQ---NLEN-DEGDFQSNgsslntvfrirdagrsstrSSL----------WSFSTLSNTTQLSYrecfsWTRHPLIQKNR 127 coelacanth
XP_001378766 122 RVVLASFLLLSLGLMLILVGVGLQVTP---SPGVSSAIF--FVPGFLLLIPGVYHVIFIYLGVKGHRGFQFFYLPYF 193
XP_003313227 122 RVVLASFLLLLLGLVLILVGVGLEATP---SPGVSSAIF--FVPGFLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYF 193
Q7T382       133 RVVLASFLLLITGVALIFTGIVIQLNP---HAGVSSAIF--FVPGFLLFIPGVYHVIYISCAVRGRRGFKFFYLPYF 204 zebrafish
Q7JNC1        92 KVIIGSIILTAVGAVLLVIGCWVAMNPdeaHSGMQHWVF--FFAGLVCFIPGFYHVYYVTCTLCGRPGYSFDKLPTF 166 Caenorhabditis ele...
XP_002877160  48 KSIALAVFLLLLGCLLLLLSFFIFIGH---MEGDSSQGYalLVLGILTFLPGFYETRIAYYSWRGAEGYRFAAIPSY 121
XP_015617548  75 KSIALALFLLLLGCSLLFLSYFIFTGH---MEGDNSQAYglLFLGILAFLPGFYETRVAYYSSRGAPGYTFASIPDY 148
ETN66617     115 RTVLAATALLIIGTGLIAMGAYALAEP---HNGSQAAVF--FVAGFICFVPGAYHVVYIWLAARGYRGFDFYHLPLF 186
EFX88775     121 KVVATAFALVIIGLGLLVTGITVLIIP---SGGVQGLVF--LIIGVICFIPGAYHIVYIYLAVKGRKGYNFYHLPLF 192
XP_006013320 128 KVVLASFLLLTVGLVLVFTGMALQVNP---TAGLSSAIF--FVPGFLLLIPGVYHVTFIYCAVRGKKGFRFFYLPYF 199 coelacanth
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap