1XHX


Conserved Protein Domain Family
DNA_pol_B_2

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pfam03175: DNA_pol_B_2 
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DNA polymerase type B, organellar and viral
Like pfam00136, members of this family are also DNA polymerase type B proteins. Those included here are found in plant and fungal mitochondria, and in viruses.
Statistics
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PSSM-Id: 367375
Aligned: 35 rows
Threshold Bit Score: 245.331
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XHX_A     53 KVQADLYFHNL-K--FAGAFIINWLERn--------------gFKWSADGLPNT-------------------------- 89  
P22373    438 YRNVLFYAHNLgK--FDAVFLLKELLRfnltteglnnpyefpaPLTRNSDILKLtikrtvdgktr-------kvtimdsf 508  ergot fungus
Q01529    456 DDKKIKVKKKKpIsdVNKKSQNKDHYEi--------------sTILRDDRILKCvikvktpsgyn-------kitfidsy 514  Podospora anserina
O78938     73 YKNYKVYLHNFaK--FDGYFLVKYLSKlgf----------idnIIINKGRIITLkfiynkysi-----------tfkdsy 129  Agrocybe aegerita
P33538    407 YDGYKVYTHNFsY--FDGIFIIDILSRlge-----------vkPFMRNGKILKLtfnftlpnskrk-----ytlyfmdsl 468  Neurospora interm...
P22374    595 NHGKKFYVHNLaH--FDSVFILDTLSKlgk-----------idIIMRDDKIMKLkitfkipgknte-----ysisfldsl 656  Ascobolus immersus
Q9TEH5    311 NLPGYIYVHNLtK--FDAYFILKIIYDnfv-----------vkPLYKDRTILQLdmtlktfetntkkc-knkrmvlkdsy 376  Morchella conica
P33537    371 YDKHTVYCHNFsK--FDINFIIKILVQefv----------vekIISKDLDILSIkisykfepkkkggkaerhtitiadsc 438  Neurospora crassa
CBJ14035  150 PEIQTVYFHNFsR--FDGILILRHLVLhnde--------yeirPLMRNGRLYEVvvyfkkrml----------frfrdsl 209 
P10582    301 GSSMVVYFHNLsQ--FDGIMILSFLTKsykn--------chiePIMRNDCIYSIklykvskngdkr-----lvltfmdsy 365  Zea mays
1XHX_A     90 --YNTIISRMGQWYMIDI----CLGYKGKRKIHTVIYDSLKKLPFPVKKIAKDFKLTVLKgdidyhkerpvGYKITPEEY 163 
P22373    509 alLPRSLRDLCKDYNIDNpk-sYFPYLFSVDSHLFYTGATPNINYYLDIPKAEYLKLVKD-----------DWDFKDETL 576  ergot fungus
Q01529    515 niLPDKLDNLAKSFGTEIqk-gLFPYEFVKSNTLNYVGITPSIEYYKIN------NEVISqelyn-elivpQWDLRKQTL 586  Podospora anserina
O78938    130 llLPSSLRKLCKSFNTQTqk-dIFPYLLDD---INYIGEVPDYKYFCNLEMEEYNNYKSNf---------kVWNFREEAI 196  Agrocybe aegerita
P33538    469 liLPDSLDKLSNFFNNKVkk-lFFPHSFLDDNTIPINYVGKCPDYKYFPKAYTEDFTIEQyqeyankfknnNWDLKKELI 547  Neurospora interm...
P22374    657 lmLPNSLDNLSKAFNIENkk-sVFPLKFTNGAVTPFNYIGAVPGYEYFYNTPNKKFTKDDykkyc-kdfnnNWDFNKELK 734  Ascobolus immersus
Q9TEH5    377 llLPESLKRLGTNFNTNIqk-gYFPYDFVNENRLEY-----IGEIPNYQYFKNQLTQTEYdeikn-spdssKRDLKKETI 449  Morchella conica
P33537    439 rlLPGSLDKLAKDHNI-ItkkgKFPYKFVNKDNLEYVGLLPDYEYYIDPKKGEMITLFEWaam-----ytnKWSMRKETI 512  Neurospora crassa
CBJ14035  210 nlLPGSLDYLSSNLCPELgnkgSFDHSSMNlen-----------------------------------vkkKRDVVIE-- 252 
P10582    366 llLKVKLADLADSFCPELggkgSFDHQNVT-----------VDKLP---------------------------SIREDSL 407  Zea mays
1XHX_A    164 AYIKNDIQIIAEaLLIQFKQGLD---------RMTAGSDSLKGFKDIiT---T-----------------KKFKK----- 209 
P22373    577 EYLNLDLISLHQ-VLVKVNKAINflfdieftsCATVSSLANKIFLSK-F---Y-----------------DDKNKa---- 630  ergot fungus
Q01529    587 HYLERDLLSLLE-IINTYNHYVYkrynvqlteSLTIARLALNIYLKR-Y---------------------LGDNL----- 638  Podospora anserina
O78938    197 KYCNLDCISLYE-ILYKFNTLVFnkfelninkYPTLPSLSFALFKTK-Y---------------------LKENE----- 248  Agrocybe aegerita
P33538    548 KYCEIDTIALYQ-VLVSFQRKIYekfmidctkYPTIPSLAFAIFRKK-Y---------------------LVEDM----- 599  Neurospora interm...
P22374    735 NYCEIDCLALHD-ILTLFAKMIHnefsvditrYVSLSSITFAIFRTN-F---------------------LPENK----- 786  Ascobolus immersus
Q9TEH5    450 KYLEQDIKTLCE-VLIKFSDEIWeere-nitkCSSLSGLAYLIFKTN-Y---------------------IKDSK----- 500  Morchella conica
P33537    513 IYLEKDIKALYQ-LMMEMSNNTYstfrinitrVKTASALAFLVYRTI-FlpnEveeenetnspnnilslfDKKEEkkltp 590  Neurospora crassa
CBJ14035  253 -YMKQDIRLLGG-VMQKAQDIYWnlfevdlvdWITVASQALGIFRMN-F---F-----------------NDMDF----- 304 
P10582    408 TYLKQDILITAA-VMQRAKAIIWeeygidilkVLTISALALKIFRRV-Y---Y-----------------KDDDDn---- 461  Zea mays
1XHX_A    210 --VFPTLSLGLDKEVRYAYRGGFTw-lNDRFKEKEIGEGMVFDVNSLYPAQMYSrLLPYGEPIVFEGKYVWDEDYPLh-- 284 
P22373    631 --IPLVKDIDLFNDIHEAYYGGRVevfNPIIMADSTKSYYYYDVNSLYPFASIN-DIPGLKCTFYEVVKANVNIHEL--- 704  ergot fungus
Q01529    639 --IPVVLNNSLFTSIKAAYYGGVAevyRPY-----GKNLRYYDVNSLYPFVAKN-TMPGHECKYIESKKGLKLSEl---- 706  Podospora anserina
O78938    249 ---VHMLSGSIATNIRKSYTGGSVdmyIPLIEK--DSKIFIYDINSLYPFSMKSfKFPIGNPTFFKGDITRINKDa---- 319  Agrocybe aegerita
P33538    600 ---IPNIKSKLHNIIKLSYFGGICelyKPF-----GVNIKSYDVNSLYPFAMKYfKMPSGIPKYVKGTLQNIVRFTDsic 671  Neurospora interm...
P22374    787 --IPNITCTKLHYILKQAYTGGYCdvfKPE-----GKNIHSYDINSLYPSAMAKfDMPTGTPLHILG---DPYKFTKd-- 854  Ascobolus immersus
Q9TEH5    501 ----LSMVKGVAHEIWEAYYGGRCevsYPC------IKTKSYDCNSIYPYCMLK-DMPVEN-LFEVTIIILIi------- 561  Morchella conica
P33537    591 kyFLPKLKGRLERAVRAAYFGGRNeifIPI-----INNIFSFDFNSLYPTAMMM-PMPVGIP-------VHTFCKNLne- 656  Neurospora crassa
CBJ14035  305 --HIHIPNRNEDTFIRRGYYGGHAdayIPK-----GTNLYYYDVNSLYPFIMKEyPMPSGKPVWASNLGGMDLDSl---- 373 
P10582    462 --WIYIPDDNEAQFIREGYYGGHTdvyKPY-----GENLYYYDVNSLYPSSMLD-DMPIGKTRWVSDLGSKKSKIVLnd- 532  Zea mays
1XHX_A    285 ---IQHIRCEFEL---KEG--YIPTIQIKrsrfykGNEYLKSSGGEIADlWLSNVdlELMKEHYDL-YN-VEYISGLKFK 354 
P22373    705 ---FGFFYCKIKSp--DNL--YLGLLPKR------TETSLIFPGGAWEG-WYFSE--ELKFAVAHG-YE-VEIIKGYNFD 766  ergot fungus
Q01529    707 ---FGFFYCKVTT---NNQ--YLGLLPVH-------NQGLIMPNGQWYG-WYFSE--ELKFAEVNG-YN-IEVIKGYQFN 766  Podospora anserina
O78938    320 ---FGFFYCKIITpeyLEH----PILQTHlk--tsDGIRTLAPLGSWEDmLFSE---EMYNAMKYG-YK-FEILWGYTFE 385  Agrocybe aegerita
P33538    672 evpFGFYNVKVKTplnLDK----PFLPTRln--tpAGTRTAFPLGQWEG-WYFSE--EILNAMKHG-YE-FEFIEGYLFE 740  Neurospora interm...
P22374    855 --pFGFVFAEVTAp---DL--KVPIIQTRvq--tsGGVRTVAPIGTFKG-WYLLD--ELINAKKYG-YT-FKISEAYLFE 920  Ascobolus immersus
Q9TEH5    562 ---FRYVYAKIK----TIGntKYPFIPFR------SETGLLFPLGSWED-WYFSE--ELKYAVKSGlYQ-VEVIHSYKYE 624  Morchella conica
P33537    657 --iFGFVRAKIITpa-----iNIPVLPCRvk--vnGVQKLIFPIGEWTG-WYFSE--ELKLAVEYG-YK-IEVLESYVFE 722  Neurospora crassa
CBJ14035  374 ---YGFIEAYVECpesIVR----PFLPYHk----vKDPTLLFPTGEWIGvYYTE---ELKYAKSLG-YTvIPIK-GYLFQ 437 
P10582    533 --mFGFIRAFIICpkhIKK----PLLPYKk-----DDGTIIFPTGRFLG-VYFSE--ELKYAVSLG-YK-VYPICGYIFD 596  Zea mays
1XHX_A    355 ATTGLFKDFIDKWTYIKTTSEG----AIKQLAKLMLNSLYGKFASNPDvTGKVPYLKENGAlg--fRLGEEETKDPVYTP 428 
P22373    767 RVSNVFNEFVQEVYKVKCNPNNv---TEKNIAKLILNSLIGRFGMNIN-KIKTSLVPSEKHn---eLLTTRVVKSTTDLG 839  ergot fungus
Q01529    767 KIDNLFSSYVDDLYKIKANSEGs----EKLITKFLLNSLLGRFGMSIF-KLKTDIVSVEKAk---kLAVTNYINSVKAIS 838  Podospora anserina
O78938    386 S-KNIFSEIISDLYKMRLEYQKs--dPMNYIAKILMNSLYGRFGMDDN-FTFSDIMDKDDYfnfekLDRNNSILDVTELN 461  Agrocybe aegerita
P33538    741 E-SSMFDEYIDLLYNIKKNSPKe--sPWYYISKLLMNSLYGRFGLNPE-GEEIFITSEEEGd---aIIATKEYVTITPLS 813  Neurospora interm...
P22374    921 R-LNIFKEYIHRLYTIKSSYTPd--dPMYFIAKLLMNSLYGRFGMDPI-TIKYSVLTPEESe---eKLKNSSCIEATTLP 993  Ascobolus immersus
Q9TEH5    625 AGVDIFKDYVEKYYGLNPVLEQv--lWEEPTAKLLLNGLYGRFGMNPH-TTQATIVASADLp---tFILDNDVIDYFTIF 698  Morchella conica
P33537    723 KRDDPFKEYIEHFASIKDNTKGs----KKQMAKLLLNTLYGRTGMNDS-AAEIKMLTTNELdn--iQLTNNVIHEFEVDD 795  Neurospora crassa
CBJ14035  438 KRESPFKDYVGSLFERRLQAKEdgneAMSLLYKLVMNSLYGRFGIHPK-STKTDIGGIKEYq---yRMRQESWLDGDYLG 513 
P10582    597 RKESPFKRFVYDIYSKRLDAKAkgekALDFIYKITMNSLYGRFGISPE-STTTQIVSTEESrk-laLYNDGFVQSYELSS 674  Zea mays
1XHX_A    429 MGVFITAWARYTTITAAQACY-----------------DRIIYCDTDSIHLTGTEIPDVIKDI 474 
P22373    840 SGMFMDIYVPGIDKNICEDFN-----------------LDYIEVLNSTNTDEKGTMPDNNVSI 885  ergot fungus
Q01529    839 DTDVLISYNKEISRKLVEEHGl---------------nYIEILNSNSKLDLEKNNSFKDVAVS 886  Podospora anserina
O78938    462 NNNFLVTTKNPKVELDTILDNgse------------khDINIAIASAITAYSRIQMSKFKNNp 512  Agrocybe aegerita
P33538    814 SGNVLISAKLPEEAFGDMNIS--------------------VPISSAIAAYSRIHMSHFLTKY 856  Neurospora intermedia
P22374    994 SGNVLFKENKPLGEFSNLNTS--------------------VPISAAIAAYSRMIMSEYLIKY 1036 Ascobolus immersus
Q9TEH5    699 VGYEWVTYTPKKFASDNIVRKensplt-----nfhaelEQSVQISIRITAYARICMAETIKHV 756  Morchella conica
P33537    796 DKHYVRYDKKPCPVLCAQSEKnyellsyldgekddgfiINSTSIAAATASWSRILMYKHIINS 858  Neurospora crassa
CBJ14035  514 NDKYVLSYHTNMDNTIDRWDPp---------------kNSAIQLAAAITACARIYMYKYTSRE 561 
P10582    675 DKCLVTCKNVRSLDLLKLSSDrp--------------tYAAVQISAAVTGYARIRMHPFISRD 723  Zea mays
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