2WKN


Conserved Protein Domain Family
FmdA_AmdA

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pfam03069: FmdA_AmdA 
Acetamidase/Formamidase family
This family includes amidohydrolases of formamide EC:3.5.1.49 and acetamide. Swiss:Q50228 forms a homotrimer suggesting all the members of this family also do.
Statistics
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PSSM-Id: 397271
Aligned: 71 rows
Threshold Bit Score: 188.933
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2WKN_A                62 RDVDLSTVHFLSGPVGVKGAEPGDLLVVDLLDIGAR------------------------------------------DD 99 
BAK18187              69 ITPTIRGGHEVTKPVYVEGAEVGDAIVIQIKSIQVTsiatssgtdeaqnerfigdpfvkvkcpgcgklhpptivqgigQE 148
jgi:Bsel_1905         46 itpclKGGHEVTKPVFVEGAEVGDAVAIRIKSIRVTsiatasgndapvdgrflgdpfvavkcpecgemnpqtvikgigQD 125
Q5L060                46 ITPCIRGGHEVTKPVFVEGAEVGDAIAIKIKSIRVTsiatssgndkpmegrfvgdpfvavkcpqcgtmypetkiegigPE 125 Geobaci...
WP_013076505          49 ITPAIRGGHEVTRPVFVAGAEVGDAIAIRIQSIRVTsiatasgndrtvegsflgdpfcaakcpvcgtmypetriegigPH 128 Kyrpidi...
goetting:Curi_c07590  45 ITPALRGGHEVTRPVFVENAEIGDAVAIYIKSITVTssvassgnevaveknfvgdpfvagrcpncgtlypetklegigSA 124
BAM01204              63 ITPAIRGGHEVTRPVAVAGAEVGDAIVIRIKDITVTslatssgndrimsgrflgdpyvagkcpqcgtlypktvlrgigQT 142
jgi:Cwoe_3284         54 ITPAIRGGHEVAQPVAVEGARVGDAIAIRIKDISVTslatssgndqamdgrfngdpycaavcpgcgdewpattldgigPT 133
jgi:Sthe_1570         51 ITPAIRGGHEVTQPVAVEGAEVGDAIAIRIKDIVVTsiatasgndqvmagrflgdpyvagrcpecgtlypetriegigPT 130
jgi:Dshi_4177         52 iTPRLRGGHEVTTPVHVQGAEVGDGVAIRIRDITVTslatasghdsspegfclgdpyvaarcpvcdtvwpethvegigQD 131
2WKN_A               100 S---------------LWGFNGFFSKQNGGGFL--DEHFPLAQKSIWDFHGMFTKSRH----------IPGVNFAGLIHP 152
BAK18187             149 SvkcmtcgtdttpfkiSNGYTMTFNSKGNVGLTvgKEAARRIAQDSKNYMRTPENSVQnpitsfapsdLIGVLARMRPFV 228
jgi:Bsel_1905        126 AircencdadvtpfrfTNAYTMTFNDQKTVGITldKQGAEQVAHDGKSYMSTPENSVQnpivtfaphdLVGAIARVRPFL 205
Q5L060               126 AircancgadvtpfvfTNGYTMTFDPNRQIGVTvhKEAAEHIARQGRYYMATPDNSVQnpivtfaphdLVGTVARLRPFL 205 Geobaci...
WP_013076505         129 SirctncgadaspfqfTNGYTIAFDENYELGVTlpRDAAERIAADGRQFMATPEHSIQnpivtfaphdIVGAVARVRPFL 208 Kyrpidi...
goetting:Curi_c07590 125 SvhcakcdeeiaafqfTNGYTIALNENKTIGVTltKEASEEAAKKAKSYMAVPDNSIQnpvvtfaphdIVGNISRLKPFI 204
BAM01204             143 AvrcancgadaspftfTNGYTIVFDANRSVGITlhKEAAEAIAWEAKRYAALPDNSIQnpiltfaphdLVGLVARLRPFM 222
jgi:Cwoe_3284        134 AvrcarcgadatpftfTNGYTIAFDEQHAVGVTvgREAAERFAREAARAAALPDGSVQnpiltfaphdVVALATRLRPFM 213
jgi:Sthe_1570        131 AvrcvncgadatpfifTNGYTIAFDENRQVGVTlhQQAAESIAREAERYAALPENSIQnpiltfaphdLVGVVARMRPFL 210
jgi:Dshi_4177        132 AvkcdscgnavtpfeiVHGYTVTFDETRSVGLTlpQEAAETLARDADHYAALPDASRQhsiltyapsdMPGTLVRMRPFM 211
2WKN_A               153 GLIGCLPDPKMLASWNE----------------RETGLiATdpdripglanppnattahmgqmqgeardkaaaegartvp 216
BAK18187             229 GQLGTTPSKAMPDSHNAgdfgtfligapheftmTEDELnIH--------------------------------------- 269
jgi:Bsel_1905        206 GQLGTTPSRPIPDSHNAgdfgqfligaphdyglTEDEL-ED--------------------------------------- 245
Q5L060               206 GQLGTTPARPLPDSHNAgdfgqflinapheygiTKEQL-ED--------------------------------------- 245 Geobaci...
WP_013076505         209 GQLGTTPSRPMPDSHNAgdfgsfllgaphqyalTQEELdEA--------------------------------------- 249 Kyrpidi...
goetting:Curi_c07590 205 GQLGTTPSIPMPDSHNAgdfgsfllgapheyalTEEELlKH--------------------------------------- 245
BAM01204             223 GQLGTTPSIPFPDSHNAgdfgsfligapheyglSAEQL-AH--------------------------------------- 262
jgi:Cwoe_3284        214 GQLGTTPSTTIPDSHNAgdfgsflvgaphryalTAQELqQH--------------------------------------- 254
jgi:Sthe_1570        211 GQLGTTPAIDMPDSHNAgdfgsflvgapheygiTVDQL-AH--------------------------------------- 250
jgi:Dshi_4177        212 GQLGTCPSMAMPDSHNAgdfgaflvgaphdyaiTAEQLaEH--------------------------------------- 252
2WKN_A               217 prEHGGNCDIKDLSRGSRVFFPVYVDGAGLSVGDLHFSQGDGEItfCG-AIEMAGWVHMKVSLIKGGmakyGIKNPIFKP 295
BAK18187             270 --RTDGHMDINRVREGAVVICPVKVPGGGVYVGDMHAMQGDGEI--AGhTTDVSGIVQLQVSVLKKV----NLDGPILLP 341
jgi:Bsel_1905        246 --RTDGHMDINRAREGAIVIAPVKVEGGGVYLGDMHAMQGDGEI--AGhTTDVSGIVTLQVNVIKGL----KLEGPVILP 317
Q5L060               246 --RTDGHMDINRVREGAVLICPVKVRGGGVYLGDMHAMQGDGEI--AGhTTDVSGIVTLQVKVIKGL----TIDGPILLP 317 Geobaci...
WP_013076505         250 --RTDGHMDIARVREGAILVCPVKVPGGGVYLGDMHALQGDGEI--AGhTCDVSGVVTLQVHVIKGA----NLEGPILIP 321 Kyrpidi...
goetting:Curi_c07590 246 --KTDGHMDINRAREGAIVICPVKVKGGGVYVGDVHAMQGDGEI--AGhTCDVSSVVTLKVKVIKNL----NIDGPIILP 317
BAM01204             263 --RTDGHMDIDAVRAGAILICPVKTPGGGVYLGDMHALQGDGEI--AGhTCDVSGTVTLQVHVLKNL----PIDGPILLP 334
jgi:Cwoe_3284        255 --KTDGHLDVDAVRAGAILICPVKVDGGGVYMGDMHALQGDGEI--AGhTADVSGTVTLQVEVVKGL----GIDGPILLP 326
jgi:Sthe_1570        251 --RTDGHLDVDAVRAGAILICPVKAPGGGVYMGDMHALQGDGEI--AGhTCDVSGVVTLQVHVIKGL----NIDGPILLP 322
jgi:Dshi_4177        253 --KTDGHMDIDAVRAGAIIVCPVKVPGAGVYMGDMHAGQGDGEI--AGhTMDVSGSVTLQVEVVKNY----PIDGPVLFP 324
2WKN_A               296 ---------------------------------SPMTPnykdyLIFEGisvdeKGKqhylDVTVAYRQACLNAIEYLKkf 342
BAK18187             342 nvedlpytakpftkee-kriarelaeefgvkqvEESFP-----LSVVG-----TGA----NLNVATENALERAAKLFE-- 404
jgi:Bsel_1905        318 veedlpylakpitkaereeakrlhagwsmqqplESSLP-----LSFVG-----TGA----TLNDATTNGLERAAMVLG-- 381
Q5L060               318 vaedlpylakpltkke-keialdlaqswgvnklEESLP-----ISFVG-----TGA----NLNEATENGLQRAAKTLG-- 380 Geobaci...
WP_013076505         322 needlpylarpltese-kalakaqatkwgfdaiEETAP-----VSVVG-----SGA----TLNAATDNALERAARLFG-- 384 Kyrpidi...
goetting:Curi_c07590 318 veedlpylakplnvee-kkramelasewgieslENTAP-----ISFVG-----TGS----NLNEAIDNGLTRAAELFN-- 380
BAM01204             335 vaedlpflakplsaee-karalaiarqwglealEESAP-----ISVIG-----TGP----DLNAATDNGLERAARLLE-- 397
jgi:Cwoe_3284        327 vaedlpflakpltase-raraaalgarygvaelEESLP-----ISVIG-----TGP----DLNSATDNGLARAAELLG-- 389
jgi:Sthe_1570        323 vaedlpflakpltaee-raraealaqawgvpalEESAP-----ISVIG-----TGP----DLNSATDNGLQRAADLLE-- 385
jgi:Dshi_4177        325 leedlpplarpfteae-kakgdrlaakwgvkeiEPLAP-----ISVIG-----TAA----NLNDAIENGLARAATLLD-- 387
2WKN_A               343 gysgaqayslLGTAPVQGH--ISGVVDV---PNACA 373
BAK18187             405 ----------LTVEEVRNRatITGGIEIgrhPGVVT 430
jgi:Bsel_1905        382 ----------TSVPEVMNRatVTGAIEIgrnPGVVT 407
Q5L060               381 ----------ISVPEVMNRatITGAIEIgrhPGVIT 406 Geobacillus kaustophilus
WP_013076505         385 ----------MSVPEVKNRatITGSIEIgrhPGVVT 410 Kyrpidia tusciae
goetting:Curi_c07590 381 ----------ISVPEVKNRttINGAVEIgryPGTat 406
BAM01204             398 ----------MSVPEVKNRatITGAIEIgrhPGVVQ 423
jgi:Cwoe_3284        390 ----------MSVPEVMNRatIAGAIEIgrhPGVVQ 415
jgi:Sthe_1570        386 ----------MTVPEVKNRatITGAIEIgrhPGVVQ 411
jgi:Dshi_4177        388 ----------MTVAEVRNRatINGAIEIgraPGVIQ 413
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