Conserved Protein Domain Family
Pap_E4

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pfam02711: Pap_E4 
E4 protein
This is is a family of Papillomavirus proteins, E4, coded for by ORF4. A splice variant, E1--E4, exists but neither the function of E4 or E1--E4 is known.
Statistics
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PSSM-Id: 367150
Aligned: 40 rows
Threshold Bit Score: 38.0549
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P27225     3 DDTAPHPptQRYPLLDLLSWyn-kcAPqthctPQRPLTTTTqtVQTEQHttcpsKPH-RHENDTDSvdsrHHSTCSTQTP 80  human papillomaviru...
AAA79191  46 LYLVPKRh-CQYPLLALLNT------------PDQPIPHHV--PTTPQKq---sRAR-RRLENELE----STAQTSNHTA 102
CRF31104  21 LYLALY---EKYPLLNLLHT------P-----PHRPPPLQC--PPAPRKt---aCRR-RLESEHVD---------RPLT- 70 
AAA79482  46 LYLVLC---KTYPLLGLLHTpppppPP-----PLHRPHLHC--PPAPPRn---aWTR-RHVNDPED------PPQTPTTP 105
Q8B5W6    40 LYLVLC---KTYPLLGLLHTp---pPP-----PLHRPPQQC--PLPPPRi---tWTR-RPVKDPEDvpptPTPPTTPTTP 102 Human papillomaviru...
Q2I2S0    21 LYLVLY---KKYPLLGLLHTp----PP-----PPHRPPPQC--PAAPRKn---vCKR-RLVNDNEDl---HVPLETPRTH 79  Human papillomaviru...
O37388    21 LYLVLC---KKYPMLGLLHT-----PP-----PLHRPPTQC--RPVFQKn---vCKR-RLLNDNEDl---HNLQEKPNTP 78  Common chimpanzee p...
P26549     3 DPEV-----IKYPLLKLLTQr-----------PPRPPTTKV-----------------HRGQSDDD----SIYQTPETTP 45  human papillomaviru...
Q9IR55     1 MYLVPTA--PRHPLLQLLNSy----RT-----PPRPIPIPP--PRAPQK------PRhHNNENDSD----LLSPTPPQSP 57  Human papillomaviru...
Q6LCS0    81 LCLVPVD--TTYPLLRLLTNttt-------tgPPPPPPP----LWAPKT------PR-YPTDQENDpeqvNQNLTPPESP 140 Human papillomaviru...
P27225    81 ASPAS--PAHPWTLDCVGSEL--TVKTVTSDGTTVEVRLRL 117 human papillomavirus 42
AAA79191 103 -------PQTPWAVTTTGTSV--TITTRTKDGTQVVVTLHL 134
CRF31104  71 -TPCVwpTLDPWTVQSTTSSL--TITTSTKEGTTVTVQLRL 108
AAA79482 106 GTPSVsdTATPWTVQTTTSTL--TVTTVTKDGTTIFVQLRL 144
Q8B5W6   103 EAPCVsqTETPWTVQTTTSSL--TITTITKDGTTVTVELRL 141 Human papillomavirus type 74
Q2I2S0    80 KALCVsqTTTPWTVQTTTSTL--TITTITKDGTTVTVQLRL 118 Human papillomavirus type 13
O37388    79 ATLCVtqTVQPLTVQTTTSTI--TVTAVTTDGTTVTVLVHL 117 Common chimpanzee papillomavirus 1
P26549    46 STPQSi-QTAPWTVDHEEEDYtvQLTVHTKGGTCVVLKFHL 85  human papillomavirus 58
Q9IR55    58 --------RCPWTPATTKYTV--ELQAQTPEGTSVQLKLRL 88  Human papillomavirus type 82
Q6LCS0   141 THTVS--QQTQTSVTTPTVEV--HVSTHK---ATVVIKLRL 174 Human papillomavirus type 66
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