Conserved Protein Domain Family
GntP_permease

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pfam02447: GntP_permease 
GntP family permease
This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter and GntT, a high affinity transporter.
Statistics
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PSSM-Id: 308194
Aligned: 11 rows
Threshold Bit Score: 443.26
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q46892   4 ITLLCIALAgVIMLLLLVIKAKVQPFVALLLVSLLVALAAGIPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSG 83  Escherichia coli K-12
P0AC94   4 LNILWVVFG-IGLMLVLNLKFKINSMVALLVAALSVGMLAGMDLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSG 82  Escherichia coli K-12
P39357   1 MPLIIVVAG-IALLLLLTIKIKLNTFVSLIIVSIAVAIASGMDLSKVVTSVESGLGGTLGHIGLIFGFGVMLGRLLADAG 79  Escherichia coli K-12
Q65CW3   1 MPLLIVAIG-IVALLLLIMGLKLNTFVSLIIVSFGVALALGMPFDDIVKTIEQGLGGTLGHIALIFGLGAMLGKLIADSG 79  Bacillus licheniformi...
P39835   1 MPLVIVAIG-VILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLDKVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCG 79  Escherichia coli K-12
P39344   1 MPLIIIAAG-VALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTG 79  Escherichia coli K-12
P0AC96   4 LTLVLTAVGsVLLLLFLVMKARMHAFLALMVVSMGAGLFSGMPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETG 83  Escherichia coli K-12
P71364   6 IPIIGLLIA-VFVLVFLVLRTRVHAFIAMLIAASIAGLVGGMSADETLNSITKGFGGTLGSIGIVIGLGVMMGSVLEVSG 84  Haemophilus influenza...
P08555   6 WVVSTLLIS-IVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSG 84  Escherichia coli K-12
Q9ZIJ1   9 YLLLDALVT-IIGLIVLITRFKVHPFIALIIAAGFLGLTSGMPVEKIVKSFQDGFGGVLGFVGVILALGTMLGKLMADSG 87  Pseudomonas aeruginos...
Q9Z670   7 MLLLYALAS-IIILILMIAKWRLNPFVSLILVSIGMGAVTGMPLTKVLSAFQDGLGSGIGSTASVIALGTMLGKILAESG 85  Zymomonas mobilis sub...
Q46892  84 GAESLANYFSRKLGDKRTIAALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPPHPG 163 Escherichia coli K-12
P0AC94  83 AAHQIAHTLLARLGLRYVQLSVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQPG 162 Escherichia coli K-12
P39357  80 GAQRIALTMLNYFGKNKLDWAVVCSAFIVGIALFFEVGLILLVPILFAIAREAKISPMFMCVPMLSGLLVAHGFLPPHPG 159 Escherichia coli K-12
Q65CW3  80 GAQRIAMTLVNKFGEKNIQWAVVIASFIIGVALFFEVGLVLLIPIVFAISRELKISILYLGIPMTAALSVTHGFLPPHPG 159 Bacillus licheniformi...
P39835  80 GAQRIATTLIAKFGKKHIQWAVVLTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPG 159 Escherichia coli K-12
P39344  80 AAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPG 159 Escherichia coli K-12
P0AC96  84 AVDQIAVKMLKSFGHSRAHYAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVPGPA 163 Escherichia coli K-12
P71364  85 AAEKMAYSFIKMLGQKKEEWALAITGYVVSIPIFVDSAFVILYPVAKALAKNGKRSLLTLGVALAGGLAVTHHTVPPTPG 164 Haemophilus influenza...
P08555  85 AAERIGLTLQRCRWLS-VDVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPA 163 Escherichia coli K-12
Q9ZIJ1  88 GADQIARTLIRAFGKERVHWSMMLAAFLVGIPLFFEIGFILLIPLVFIVARRSGVSLIKIGIPLLAGLSAVHGLVPPHPG 167 Pseudomonas aeruginos...
Q9Z670  86 GAERIATTTIKIFGPKLIHWAMLVIAFIVGIPIFYQVGFILLIPLVFTLGRASGISLVKLTIPLCAGLATVHGLLPPHPG 165 Zymomonas mobilis sub...
Q46892 164 PVAAAGLLHADIGWLTIIGIAIS-IPVGVVgyfAAKIINKr-qYAMSVEVLEQMqlapASeEGATKLsDKINPPGVALVT 241 Escherichia coli K-12
P0AC94 163 PVALVNAYGADMGMVYIYGVLVT-IPSVIC---AGLILPK---FLGNLERPTPS----FL-KADQPV-DMNNLPSFGVSI 229 Escherichia coli K-12
P39357 160 PTVIAREYGADVGLVLIYGIIVG-IPTFIL---CGPVLNK---FCQRIIPDAFKkegnIAsLGATRRfSESEMPGFGISF 232 Escherichia coli K-12
Q65CW3 160 PTAIAGELGANIGEVLLYGIIVA-IPTVLL---AGPLFTK---LAKKIVPQSFEkmgsIAsLGEQKTfKLEETPAFGISV 232 Bacillus licheniformi...
P39835 160 PTAIATIFNADMGKTLLYGTILA-IPTVIL---AGPVYAR---VLKGIDKPIPEg------LYSAKTfSEEEMPSFGVSV 226 Escherichia coli K-12
P39344 160 PTAIATIFEANLGTTLLYGFIIT-IPTVIV---AGPLFSK---LLTRFEKAPPE-----G-LFNPHLfSEEEMPSFWNSI 226 Escherichia coli K-12
P0AC96 164 PMLLASQMNADFGWMILIGLCAA-IPGMII---AGPLWGN---FISRYVELHIPd------DISEPHlGEGKMPSFGFSL 230 Escherichia coli K-12
P71364 165 PLGVAGLFGVDIGAMLLTGMCMAfLPVVGIvlyAKWLDKKypnFNQEVFTEEELk---QKyDSYIESrEKKELPSLGLSL 241 Haemophilus influenza...
P08555 164 ALYVANKLGADIGSVIVYGLLVG-LMASLI---GGPLFLK---FLGQRLPFKPVp----TeFADLKVrDEKTLPSLGATL 232 Escherichia coli K-12
Q9ZIJ1 168 PLLAIGVFGADIGKTILYGLIVA-LPTAAI---AGPLFGA---LVSRYIPGTPSa--eLVeQIAHEP-ETQDLPSFGVTL 237 Pseudomonas aeruginos...
Q9Z670 166 SMQCVEMLHADVGKTILYGFIVG-FPAAIL---AGPLYGN---WITPRIQLPAHn--pFAeSLEGSSdQDKNLPGFWLTI 236 Zymomonas mobilis sub...
Q46892 242 SLIVIPIAIIMAGTVSATLMPPSHPLLG-----TLQLIGSPMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAV 316 Escherichia coli K-12
P0AC94 230 LVPLIPAIIMISTTIANIWLVKDTPAWE-----VVNFIGSSPIAMFIAMVVAFVLFGTARGHDMQWVMNAFESAVKSIAM 304 Escherichia coli K-12
P39357 233 LTAMLPVILMAVVTIIQMTHAKSAADSGlf-ynVILFLGNSTIAMLISLLFAIYTMGLGRGKTIPDLMDSCGKAIAGIAG 311 Escherichia coli K-12
Q65CW3 233 FTAMLPVIIMSISTIITLIQETMGLADNsf-laAIRLIGNASTSMVISLLFAIYTMGIARKIPIKQVMDSCSTAITQIGM 311 Bacillus licheniformi...
P39835 227 WTSLVPVVLMAMRAIAEMILPKGHAFLP-----VAEFLGDPVMATLIAVLIAMFTFGLNRGRSMDQINDTLVSSIKIIAM 301 Escherichia coli K-12
P39344 227 FAAVIPVILMAIAAVCEITLPKTNTVRL-----FFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAM 301 Escherichia coli K-12
P0AC96 231 SLILLPLVLVGLKTIAARFVPEGSTAYE-----WFEFIGHPFTAILVACLVAIYGLAMRQGMPKDKVMEICGHALQPAGI 305 Escherichia coli K-12
P71364 242 LPIVLPIVLIFIKAVVHLFVKDVPEALTsipyqIVSFLGHPVIVLALSVLISVYTLLPKADKNTTALH--LEEGVKTAGI 319 Haemophilus influenza...
P08555 233 FTILLPIALMLVKTIAELNMARESGLYI-----LVEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIAN 307 Escherichia coli K-12
Q9ZIJ1 238 ATVLLPVFLMLLKTFADVAFPDGHAFRA-----WMDMIGHPISALLLALLVALYTFGYARGFDSKKILRLLDQSLAPTAA 312 Pseudomonas aeruginos...
Q9Z670 237 FSILLPVLLMVFSSGANIFLPHGNNIRA-----FMNFMGDPVVSLLIALLVSMVTLGFWRGFSSADLLKFTNDCLGPTAG 311 Zymomonas mobilis sub...
Q46892 317 VILVTGAGGVFGKVLVESGVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLS-----EAVMGLN--P 389 Escherichia coli K-12
P0AC94 305 VILIIGAGGVLKQTIIDTGIGDTIGMLMSHGNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISaaildPATGQLV--G 382 Escherichia coli K-12
P39357 312 LLLIIGGGGAFKQVLIDSGVGQYISTLVSGMDINPILMAWGVAAFLRICLGSATVAAISTAGLVI-----PLLAVHP--N 384 Escherichia coli K-12
Q65CW3 312 MLLIIGGGGAFKQVLINGGVGDYVAELFKGTAMSPILLAWVIAAILRISLGSATVAALSTTGLVL-----PMLGQS---D 383 Bacillus licheniformi...
P39835 302 MLLIIGGGGAFKQVLVDSGVDKYIASMMHETNISPLLMAWSIAAVLRIALGSATVAAITAGGIAA-----PLIATT---G 373 Escherichia coli K-12
P39344 302 IVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVL-----PIINVT---H 373 Escherichia coli K-12
P0AC96 306 ILLVIGAGGVFKQVLVDSGVGPALGEALTGMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVM-----PVIEQLNysG 380 Escherichia coli K-12
P71364 320 ILLVTGAGGALGAVLRDSGAGKQLAEQIANLPISPILIPFIVSTLVRFIQGSGTVAMITAASISS-----PILAQIP--G 392 Haemophilus influenza...
P08555 308 ILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVA-----PMLPLYP--D 380 Escherichia coli K-12
Q9ZIJ1 313 IVMIIGAGGGFKQMLVASGVGDVIGHLAVNAQISPILLAWLVAAVIRIATGSATVATITGAGIVV-----PVIDLIPg-V 386 Pseudomonas aeruginos...
Q9Z670 312 ILLLIGAGGGFSEILYRAGVSNAMADLSHVMHLSPIMLGFIIAAVIRVATGSQTVAMSMSGGMLA-----PIIFSTPg-F 385 Zymomonas mobilis sub...
Q46892 390 IQCVLVTLAACFGGLGASHINDSGFWIVTKYLGLS-VADGLKTWTVLTTILGFTGFLITWcVWAVI 454 Escherichia coli K-12
P0AC94 383 VNPALLVLATAAGSNTLTHINDASFWLFKGYFDLS-VKDTLKTWGLLELVNSVVGLIIVL-IISMV 446 Escherichia coli K-12
P39357 385 TNLALITLATGAGSCICSHVNDASFWMIKDFFGLT-TKETLLSWTLMSTLLSISGLIFIL-LASLV 448 Escherichia coli K-12
Q65CW3 384 VNLALVVLATGAGSVIASHVNDAGFWMFKEYFGLS-MKETFATWTLLETIIAVAGLGFTL-LLSLf 447 Bacillus licheniformis DSM 13 = ATC...
P39835 374 VSPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLT-IGETIKSWSMLETIISVCGLVGCL-LLNMV 437 Escherichia coli K-12
P39344 374 ADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLT-VGETLRTWTVMETLISIMGLLGVL-AINAV 437 Escherichia coli K-12
P0AC96 381 AQMAALSICIAGGSIVVSHVNDAGFWLFGKFTGAT-EAETLKTWTMMETILGTVGAIVGMiAFQLL 445 Escherichia coli K-12
P71364 393 VNMLLAAQAATMGSLFFGYFNDSLFWVVNRMMGINdVKKQMVVWSVPTTIAWGIGGISVI-LANLI 457 Haemophilus influenzae Rd KW20
P08555 381 ISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGAT-LNETFKYYTTATFIASVVALAGTF-LLSFI 444 Escherichia coli K-12
Q9ZIJ1 387 NR-ELLVLATGAGSLILSHVNDAGFWLVKQYFNMS-VSETFKTWTAMETILSVVGLVFIL-LLSLV 449 Pseudomonas aeruginosa PAO1
Q9Z670 386 HSPELLVLSIGAGSSILSHVNDGAFWLLKEYLNMT-VSQTFKTWTVSVTIASIAALILTFgLQALG 450 Zymomonas mobilis subsp. mobilis ZM...
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