4BHM,5A4O


Conserved Protein Domain Family
PC4
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pfam02229: PC4 
Transcriptional Coactivator p15 (PC4)
p15 has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain. The DNA-binding activity of the carboxy-terminal is disguised by the amino-terminal p15 domain. Activity is controlled by protein kinases that target the regulatory domain.
Links
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Statistics
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PSSM-Id: 460501
Aligned: 156 rows
Threshold Bit Score: 37.8388
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4BHM_E                12 WEISDKRRVGISQFKKM-DFINIREYYEagGEMKpGKKGIGLTVDQYTAFLKA 63  Pyricularia oryzae
EdlabUofT:DCF50_p1407 18 SAKGWTKELSLVSWNDKeAKYDIREWSP--EHDK-MGKGVTLSNEELKKLKEL 67 
WP_013237283          18 SPKGWKKELNLVSWNDRtAKYDIRDWSQ--EHDK-MGKGVTLTVDELRELKNI 67  Clostridium
AEB15231              22 SKSGWNLELNFVSWGDRpAKYDIRSWDS--EHQK-MGKGVTFTKDELCALKNL 71 
WP_022230188          18 SSKGWTKELNIVSWNGAnPKFDLRDWAP--EHEK-MGKGLTFTNEELKNLRDI 67  Firmicutes
WP_014355807          17 LPSGWQKELNLVSWNERdPKYDLRDWNA--DHEK-MRKGITLTTDELAQLRDI 66  Acetobacterium woodii
CDA73243              18 SARGWTKELNMVSWNERePKYDLREWNP--DHTR-MGKGITLTEEEVETLKKL 67 
Q8Y9F0                18 NARGWRKELNKVSWNGRpPKYDIRDWSE--DHEK-MGKGITLTDEEAEVLKKL 67  Listeria monocytogenes
EQC78894              18 NPKGWRKELNLVSWNGRpPKFDLRDWSP--GHEK-MGKGLTLSNEEFTELKKA 67 
WP_010049570          19 NAKGWKKELNLVSWNGNqPKFDLRDWDA--THEK-MGKGLTLSNDEVKALKIA 68  Carnobacterium maltaromaticum
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