2D36,1YOA,1EJE


Conserved Protein Domain Family
Flavin_Reduct

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pfam01613: Flavin_Reduct 
Flavin reductase like domain
This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. VlmR is a flavin reductase that functions in a two-component enzyme system to provide isobutylamine N-hydroxylase with reduced flavin and may be involved in the synthesis of valanimycin. SnaC is a flavin reductase that provides reduced flavin for the oxidation of pristinamycin IIB to pristinamycin IIA as catalyzed by SnaA, SnaB heterodimer. This flavin reductase region characterized by enzymes of the family is present in the C-terminus of potential FMN proteins from Synechocystis sp. suggesting it is a flavin reductase domain.
Statistics
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PSSM-Id: 460266
Aligned: 75 rows
Threshold Bit Score: 70.7705
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2D36_A        29 MRK--FPLGVAIVTTnwKGELVG----MTVNTFNSLSLNPPLVSFFAD-------RMKGNDIPYKEsKYFVVNF----T- 90  Sulfurisphaera ...
1EJE_A        20 AHRilTPRPTVMVTT--VDEE-GninaAPFSFTMPVSIDPPVVAFASA-------PDHHTARNIEStHEFVINI----Tp 85  Methanothermoba...
XP_001525904 121 ISAv-VPRPIGFVST--ISSD-GvrnlAPFSYFTLVNHDPPIFTIGFSgg---rgNPKDTRKNILDtEECTINI----Is 189
Q7RZX5        98 SAI--VPRPIALVST--RSADGTtenlAPFSYFQVISHDPPLFTLGFAspltpasRAKDSLRILHEtGECVINL----Ms 169 Neurospora crassa
WP_000949072  19 TGSi-IPRPVAFVTS--VTKD-GvlngAPYSYFNIVAANPPLISVSVQrk---agERKDTSRNAIEkGEFVVHI----Sd 87  Bacillus anthracis
WP_012083116  17 MSRsvIPRPIAWIVT--EG---KtlniAPFSYFMALSSNPATLVVSIGhkk--dgSPKDTLKNILEtKKCTICS----Va 85  Nitratiruptor s...
Q838S6        19 SGSi-IPRPIAWVTT--QDTATGvvnaAPFSFFNAAAAEIPLATLSILrp---deEPKDTARNILAtKELVIHF----Vn 88  Enterococcus fa...
Q9HI97        25 ILY--FGTPVVLIS---TIDREGkvnlAPISSAWALGYS-VVMGIGTE---------SKTMENLREtGECTLNFpegaLw 89  Thermoplasma ac...
Q6D751        11 Y----YGFPVFLVTT--TDNSNGdvniASISSSISLGDK-IIIGVSKG---------SKTYSNLLSgSDVVINIpdykLw 74  Pectobacterium ...
Q0VL91        23 LSG--FKSANLVGTC--SDG--GeenlAMVGSCFHLGADPALMGMIMRph----sVDRHSLEYLAAtGVYTLNQ----Vh 88  Alcanivorax bor...
2D36_A        91 -DNEELFNIFAL------------Kpvkerfre---ikykegiGGCpILYDSYAYIEAKLYD--T------IDV-GDHSI 145 Sulfurisphaera ...
1EJE_A        86 aDIIERMWVTARdipagenelea----------aglawtssrrVKPpRIVEAPGHLECELLRmfE------VGD---HNL 146 Methanothermoba...
XP_001525904 190 eWFVEAANYCAInspidvdewkl----------sgltplestkVKPqHVAESAFSVEGKLIAshEwksksdPTRaT-GTL 258
Q7RZX5       170 tPFLEAANSCSTnaplgvsewvi---------sgltpvydtqtVKAaRAKEAVFAVECKLVHvkEfesrskPGEtG-STL 239 Neurospora crassa
WP_000949072  88 eSYVAAINETAAnlpsneseiel----------akltpiesdvISVpGVKEANIRMECVLERaiPlggtedSPA---CDL 154 Bacillus anthracis
WP_012083116  86 pEQITKMHESSEmlpeeiseakt----------fdistqkilaDFPpIIEGAPSAFFCRLYQkiD------LKGsK-TIP 148 Nitratiruptor s...
Q838S6        89 eDVLTQMNQTSAslaaeiseidt----------fgietiasqtVAVpAIKAAPIRMEARLHQyvPianhegQII---TDL 155 Enterococcus fa...
Q9HI97        90 eSVERLAPLTGKypvpqd-kadkfRfesnkfgvagltpcdsevVKPpRVLECRLQMEACVKSvrRise-pdVQ----AGI 163 Thermoplasma ac...
Q6D751        75 eKVEELGKLTGSdtlsegqikwgvQvchdkfskvglhteastdITPpRVIECPIQAECKTVS---------TTDkGRFIL 145 Pectobacterium ...
Q0VL91        89 eDILKAAHQTSArypreisefta----------tgltpsylpaFQApFVEEARIKLGMVVIEtqT------LAV-NDTVL 151 Alcanivorax bor...
2D36_A       146 IVGEVIDGYQIRD--NFt----------pLVYMN-RKYYKLS 174 Sulfurisphaera tokodaii str. 7
1EJE_A       147 ITGSVVSASVRSGavKEg-----------LLDVE-SVKPVLH 176 Methanothermobacter thermautotrophicus
XP_001525904 259 CIIEGVNFHVREDviNKe-----------LNNIDiSKLKPVS 289
Q7RZX5       240 VVVEGTKFWIKE-----------------------GAVNEEL 258 Neurospora crassa
WP_000949072 155 LIGRVVRFHVAEHl-YEn-----------------GRIHAEG 178 Bacillus anthracis
WP_012083116 149 LILEIESYYVEDRyaNEnf---------------dIEFQTVA 175 Nitratiruptor sp. SB155-2
Q838S6       156 FIVEITDFYFDSAv-FDe-----------------EHQYILP 179 Enterococcus faecalis
Q9HI97       164 VEVKVVRVHARNDl-IIdgkyidpkqwkpLIYSF-RHYFTLG 203 Thermoplasma acidophilum
Q6D751       146 VELDIVNVWVDSEl-LGsndvidsskwkpLIYNF-REYDTTG 185 Pectobacterium atrosepticum
Q0VL91       152 VIGAIEHILLPDNa-VEn-----------------DGFVNIE 175 Alcanivorax borkumensis SK2
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