Conserved Protein Domain Family
Flavi_NS4B

?
pfam01349: Flavi_NS4B 
Flavivirus non-structural protein NS4B
Flaviviruses encode a single polyprotein. This is cleaved into three structural and seven non-structural proteins. The NS4B protein is small and poorly conserved among the Flaviviruses. NS4B contains multiple hydrophobic potential membrane spanning regions. NS4B may form membrane components of the viral replication complex and could be involved in membrane localization of NS3 and pfam00972.
Statistics
?
PSSM-Id: 279665
Aligned: 2 rows
Threshold Bit Score: 425.595
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
P03314 2257 NELGMLEKTKEDLfGKKNLIPSSASPWSWPDLDLKPGAAWTVYVGIVTMLSPMLHHWIKVEYGNLSLSGIAQSASVLSFM 2336 Yellow fever virus 17D
P17763 2245 NEMGLLETTKKDL-GIGHAAAENHHHAAMLDVDLHPASAWTLYAVATTIITPMMRHTIENTTANISLTAIANQAAILMGL 2323 Dengue virus 1 Naur...
P03314 2337 DKGIPFMKMNISVIMLLVSGWNSITVMPLLCGIGCAMLHWSLILPGIKAQQSKLAQRRVFHGVAENPVVDGNPTVDIEea 2416 Yellow fever virus 17D
P17763 2324 DKGWPISKMDIGVPLLALGCYSQVNPLTLTAAVFMLVAHYAIIGPGLQAKATREAQKRTAAGIMKNPTVDGIVAIDLD-- 2401 Dengue virus 1 Naur...
P03314 2417 pemPALY----EKKLALYLLLALSLASVAMCRTPFSLAEGIVLASAALGPLIEGNTSLLWNGPMAVSMTGVMRGNHYAFV 2492 Yellow fever virus 17D
P17763 2402 ---PVVYdakfEKQLGQIMLLILCTSQILLMRTTWALCESITLATGPLTTLWEGSPGKFWNTTIAVSMANIFRGSYLAGA 2478 Dengue virus 1 Naur...
P03314 2493 GVMYNLWK 2500 Yellow fever virus 17D
P17763 2479 GLAFSLMK 2486 Dengue virus 1 Nauru/West Pac/1974
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap