Conserved Protein Domain Family
KOG3657

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KOG3657: KOG3657 
KOG3657, Mitochondrial DNA polymerase gamma, catalytic subunit [Replication, recombination and repair]
Statistics
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PSSM-Id: 231589
Aligned: 5 rows
Threshold Bit Score: -1
Created: 21-Jun-2003
Updated: 16-Jan-2013
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6324906     1 MDYE--RTVLKKRSRwglyvvvEQRGTSMTKLMVRSECMLRMVRRRPLRVQf--CARWFSTKKNTAEAPRINPVGIQYLG 76   baker's yeast
27923967    1 MQFHliRKYASKVSR-------EHYASSSVKIF------RRVKPPQKVNK-----PKKPENVENGPTEYAENLVKVQMIS 62   fruit fly
17537597    1 --------------------------------------MRPPKIMQIFHVS----RRQIATSKTSNFERKT----IETVC 34   Caenorhabditis el...
1706507     1 MSRLlwRKVAGATVGpgpvpapGRWVSSSVPASDPSDGQRRRQQQQQQQQQqqqQPQQPQVLSSEGGQLRHNPLDIQMLS 80   human
20141418    1 -----------------------MFYKACPSTLTCSKWIHSIIKTKKFLY----CRHYSSKSFIDNAPLRINPVGVQYLS 53   fission yeast
6324906    77 ESLQRQVFGScGGKDEVEQSDKLMELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCED 156  baker's yeast
27923967   63 RNLHAQLFPQ-APRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLP 141  fruit fly
17537597   35 PRVHNYLFPH-------VS------------------APSTSSAAEYTGVLPPLVADNVVDHFGVLAEQQTRKYKELLEK 89   Caenorhabditis el...
1706507    81 RGLHEQIFGQ-GGEMPGE--AA-VRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANL 156  human
20141418   54 PALQNQVFPQ----QNTQISQLHLDLAKFHLAKHQLLNKETIKLPSFNFRLPPLQGKTISEHFYNIGLEFAEPHLSKAIK 129  fission yeast
6324906   157 KFT----------EMVARPAEWLRKPGWVKYVPG--MAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCS 224  baker's yeast
27923967  142 LVQc--------eQLPKRPKRWAFHTGWTAYDPEd-GTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVS 212  fruit fly
17537597   90 ACEfdletaknvlEHIDKTDGWHYKTGWTRYPFStsEPPETIDFPRDSILFFDIELVVRDGTLPTLAIALGRDAWYGWCS 169  Caenorhabditis el...
1706507   157 LLQa---------QLPPKPPAWAWAEGWTRYGPE--GEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCS 225  human
20141418  130 FSKi---------DTPVQPKTWKRQPGWTKYAKD--GSISCVPYPDSDCMVFDVEVLYKVSPFAVVATAVSEDAWYCWLS 198  fission yeast
6324906   225 ---------------P--FICGGDDP-----AALIPLNTLNKEQVIIGHNVAYDRARVLEEYN-FRDSKAFFLDTQSLHI 281  baker's yeast
27923967  213 skltkhr-lsveklePldVDTDSERPhy-ttDELIPLG-TTGPGLVVGHNVSYDRARLKEQYL-TEDTGTRFVDTMSLHM 288  fruit fly
17537597  170 d----------------rLIYESEIPeiptkADLIPIGEIGMEKVIIGHNVGFDRARCREAYQsINGSKIRFMDTMSMSI 233  Caenorhabditis el...
1706507   226 qrlveeryswtsqlsPadLIP-LEVPt----GASSPTQRDWQEQLVVGHNVSFDRAHIREQYL-IQGSRMRFLDTMSMHM 299  human
20141418  199 ---------------Pw-LLGKSEND-----RQLIPSN--PKGALFVGHNVSFDRQRIREEYN-IKSSRNVFLDTMSLHV 254  fission yeast
6324906   282 ASFGLCSRQRPMFMKNNKKK--------E---AEVESEVHPeiSIEDYDD--PWLNVSALNSLKDVAKFHCKID------ 342  baker's yeast
27923967  289 CVSGVTSYQR----------------------AMLKSKKEP--AAEDLG----WLEQSSLNSLVEVHRLYCGGDt----- 335  fruit fly
17537597  234 PMYGMADHQQSLY-------------------EMYDVETND--SHSDWMN--AWKGRVSKNSLVAVHDHLYPDKainaeg 290  Caenorhabditis el...
1706507   300 AISGLSSFQRSLWIAAKQGKhkvqpptkQgqkSQRKARRGP--AISSWD----WLDISSVNSLAEVHRLYVGGPp----- 368  human
20141418  255 ATHGMCSRQKPTWFKARKAYir----sqStetSEDDDSSSFddDYQNYLKqePWLAHSSVNSLKDVAKFHCNIT------ 324  fission yeast
6324906   343 -LDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNdWNDYLN 421  baker's yeast
27923967  336 -LSKEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSN-WERYIR 413  fruit fly
17537597  291 fSKKTMRASFVKDPIEQIREDFQPLMSYCARDNILCAEIYFRLWPEFIKRFPHPATLSGMLNMGNVYLPINSY-WKMFYE 369  Caenorhabditis el...
1706507   369 -LEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQN-WERYLA 446  human
20141418  325 -LDKSKRDDFASLEKEPILQKLNELITYCAHDTYSTHQVFKKVFPQFLEVCPHPATFSAMLSLGSVFLPVNHS-WTRYIN 402  fission yeast
6324906   422 SSESLYQQSKVQIESKIVQIIKDIV-LLKDk---pDFYLKDPWLSQLDWTTKPLRLTK----K----------------- 476  baker's yeast
27923967  414 EAQLTYEDLSIEAKYHLGRRAEEACsLLLD-----DQYRQNLWLWDEDWSVQELKLKQppkrKplptv------------ 476  fruit fly
17537597  370 KNVQTCEQKKTAATRKIIESARLVAkRLDDegeeiGPEKNDVWMWHHDWTFNQKQSNF---------------------- 427  Caenorhabditis el...
1706507   447 EAQGTYEELQREMKKSLMDLANDACqLLSG-----ERYKEDPWLWDLEWDLQEFKQKKakkvKkepatasklpiegagap 521  human
20141418  403 GVEEQYQQMIQLVDqklsqyaekakdlintkdtvlkdpwlrqldwtpcnlyrklkkatqevpvvpkwykkaycktekrav 482  fission yeast
6324906   477 ---------G---------------------------VPAKCQKLPGFPEWYRQLF--PS-----------KDTVEP--- 504  baker's yeast
27923967  477 ----elkdsGntpeerrlqak------fqhlydqqalLPARRPLLPGYPLWYRKLCrkPPakradeileddEEPWSPgas 546  fruit fly
17537597  428 -------------------------------------EWFNKLFKARS---FVNLSl--------------DEVDSH--- 450  Caenorhabditis el...
1706507   522 gdpmdqedlGpcseeeefqqdvmaraclqklkgttelLPKRPQHLPGHPGWYRKLC--PRl---------dDPAWTPgps 590  human
20141418  483 itaksrlapillrlkwkkhplawsdtygwvfsvertskdeiemlldqglvpcsreedtkldynnyiffkvphkdgpearc 562  fission yeast
6324906   505 KITIKSRIIPILFKLSWENSPVIWSKESGWCFNVPHEQV-----------------------ETYK-------------- 547  baker's yeast
27923967  547 EISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVPFRSDsegvd--------------rlpmEQLLahcp--------vp 604  fruit fly
17537597  451 HIALKSHLIPAIFGFVFGPFPLFKTRSKGWGFLVPNWKPv----------------------EKALq------------- 495  Caenorhabditis el...
1706507   591 LLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDnlaklptgttlesagvvcpyraiESLYrkhcleqgkqqlmp 670  human
20141418  563 gsplsksyqryfeegilqsdyevakkalemsascsywssardrirsqmvvwdkdaelgvpssvdgfgiilpciipmgtvt 642  fission yeast
6324906   548 --A---KNYVLAD----------SVSQEEE-EIRTHNL---------------G---LQ-----CTGVL----------- 577  baker's yeast
27923967  605 efArlsASKAESDm--------aFDMLPGQvEQHLGKRehykk-----lsqkqQrleTQy---qGSGVWcnkvlddccff 668  fruit fly
17537597  496 -----dPNFHEIDa--------kIDFKPDSaVKKFPLRsfyet-----vqnnvYmlgELpispdRKGFEldeag--lvrf 555  Caenorhabditis el...
1706507   671 qeAglaEEFLLTDnsaiwqtveeLDYLEVEaEAKMENLraavpgqplaltargGpkdTQpsyhhGNGPYndvdi-pgcwf 749  human
20141418  643 rraventwltasnskknrlgselkamirapdgytfvgadvdseelwivalmgdsqfrlhgatalgmmtlegkksegtdlh 722  fission yeast
6324906   578 FKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSE---SELAHQALQINSSGSYWMSARERIQSQFVV--PSCKFPNEFQSl 652  baker's yeast
27923967  669 LKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGdpsCQAAARVIDIARMMSYWRNNRDRIMGQMVVwlDSQQLPNEFTG- 747  fruit fly
17537597  556 YQLDHPSGE-GNVGDPLTKHFAKDLKELVLRPTr-yEEYFDVVLDSIQTTQFWTSYSDRYCSEVAIwsPEATWRTAENL- 632  Caenorhabditis el...
1706507   750 FKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGp-gGASGPRALEINKMISFWRNAHKRISSQMVVwlPRSALPRAVIRh 828  human
20141418  723 sktaailgvsrdsakvfnygrlygaglkhttlllmqmnptlktaeakelakklyastkgvkskmskrlqemglpkltfws 802  fission yeast
6324906   653 saksslNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKA-NRIGSELKTQVKAPPGYCFVGADVDSEELWIASLV 731  baker's yeast
27923967  748 ------EKCQPIAYGAICPQVVACGTLTRRAMEPTWMTASNSRP-DRLGSELRSMVQAPPGYRLVGADVDSQELWIASVL 820  fruit fly
17537597  633 ----------EMIDGAIAAAVVPAGTISRRSVHKLWVTLTNQSTgHVIGTGIKAMVQAPAGYRLVGADVDSQEQWLAALY 702  Caenorhabditis el...
1706507   829 -----pDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARP-DRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVL 902  human
20141418  803 qgtesfvfnkleamaqlpsprtpvldagitqalssknlsknsfmtsrvnwaiqssavdylhlllvsmnhlikkyylearl 882  fission yeast
6324906   732 GDSIFN--------VHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTD 803  baker's yeast
27923967  821 GDAYACg-------EHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSA 893  fruit fly
17537597  703 GDASAEkrlplekrVAGKTAFSNMMLAGSKSDNTDLHSVVASQLKISRNHAKVLNYARLYGSGETHAGKHLMRVGG-LKQ 781  Caenorhabditis el...
1706507   903 GDAHFAg-------MHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQ 975  human
20141418  883 sltvhdevrylssdkdkyrvafalqvanlwtraffcqrlginelpqsvaffssvdidhvlrkdvkmdcvtpsnkvpippg 962  fission yeast
6324906   804 EETKKIANKLYENTKG-KTKRSK--------------------L------------------------------------ 826  baker's yeast
27923967  894 SEAKAKAMKMFSITKGkRVYRLReefhd-----------eledRayssyeasrla------------------------- 937  fruit fly
17537597  782 SEAESTASQLFKLTKGdVAKYMKvdvrmncvvdkyieemvensDvckiltidgiyympaytsqfasetvrfedwllshys 861  Caenorhabditis el...
1706507   976 QEAAEKAQQMYAATKGlRWYRLSdegew-----------lvreLnlpvdrteggwislqdlr------------------ 1026 human
20141418  963 eeltiesvlekleqsgqslepleqiqcfvdvkattsaeiteedkkniaylkaqafy------------------------ 1018 fission yeast
6324906   827 ----------------------FKKFWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKNLRAN-------SFLP 877  baker's yeast
27923967  938 -----------iqrnrtlaevfHRPNWQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQe-----qRFLP 1001 fruit fly
17537597  862 sllngssepdsliysiyenpdePRRLFVGGYESSTFNFLETSAAAHDLRTPILGCQIADSLGKLPEGTPdsayfdrKYKR 941  Caenorhabditis el...
1706507  1027 ----kvqretarksqwkkwevvAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEE--------FMT 1094 human
20141418      --------------------------------------------------------------------------------      fission yeast
6324906   878 SRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELP 957  baker's yeast
27923967 1002 TRINWVVQSGAVDFLHLMLVSMRWLMGS---HVRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLP 1078 fruit fly
17537597  942 SVMNWIVQSSAVDFLHLLLVSMQWLCDTYKIDARFVISIHDEVRYMCKEPDAPRLALALQLSNLLVRAYISQRVGICQLP 1021 Caenorhabditis el...
1706507  1095 SRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLP 1174 human
20141418      --------------------------------------------------------------------------------      fission yeast
6324906   958 QNCAFFSQVDIDSVIRKEVNMDCITPSNktaiPHGealdinqlldksnsklgkpnldidskvsqyaynyrepvfeeynks 1037 baker's yeast
27923967 1079 MSVAFFSSVEVDTVLRKECTMDCKTPSN----PHG--------------------------------------------- 1109 fruit fly
17537597 1022 NTVAFFSQVDCDTVLRKEVDTESINPDGsk-iADGva------------------------------------------- 1057 Caenorhabditis el...
1706507  1175 QSVAFFSAVDIDRCLRKEVTMDCKTPSN----PTG--------------------------------------------- 1205 human
20141418      --------------------------------------------------------------------------------      fission yeast
6324906  1038 ytpeflkyflamqvqsdkrdvnrLEDEYlrectskeyardGntaeyslldyikdVEKGKrtkvrimgSnfLDgtknakad 1117 baker's yeast
27923967 1110 -----------------------LRIGY------------G-------------IQPGQ--------S--LS-------- 1123 fruit fly
17537597 1058 ----------------------wTVDDLl------------------------kLTGGK-----------LD-------- 1072 Caenorhabditis el...
1706507  1206 -----------------------MERRY------------G-------------IPQGE--------A--LD-------- 1219 human
20141418      --------------------------------------------------------------------------------      fission yeast
6324906  1118 qrirlpvnmpdyptlhkIAndsaipekQLLENRRKkenridDENKKKLTRK 1168 baker's yeast
27923967 1124 -----------------VA--------EAIEKAGGn-----DVSQWDWIKK 1144 fruit fly
17537597      ---------------------------------------------------      Caenorhabditis elegans
1706507  1220 -----------------IY--------QIIELTKG------SLEKRSQPGP 1239 human
20141418      ---------------------------------------------------      fission yeast
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