Conserved Protein Domain Family
YjcC

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COG4943: YjcC 
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms]
Statistics
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PSSM-Id: 443970
Aligned: 88 rows
Threshold Bit Score: 417.395
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_014748476  21 GMRRRVLAVTLTLATLIGALPVAGSLWIAWENARRVETDLLIRATREMLTRSERLQEDATRA--LAAMAAVpVGDACTPA 98 
WP_005969766   3 FRRNSLISPVFLVLLLMLILGAVAGQLVGKGLRILEEERHMDIYMTALRDYSSRLLASARNT--LEAANNS-PFEICSPQ 79 
WP_014700212   1 -MHFSGFKKITRTIFMMI-FVSFSFLFLLNELLVSHQENKLMLRSEKLRFQAEMLAKQALSA--LNDINAI-DDDMCSPN 75 
WP_017456662   1 --mIKMLKKGVSIYIAALLLSFAFFYIVAQVAYYAFIQEKVEDYAESILARSDNIILQVREInaLREEFSV--YTPCSDP 76 
WP_083891039  18 MRYSRQLDPSNKKFFLYGMTLSLVIFYLIHILVFFNSRSRLNKYADDIFFQTEQLDFQIKRG--LSRAKLV-ASEICSEN 94 
WP_015583886   1 ----mkfihkTKWLLTGGGVAVLLSVLLTNAVMLNNQRAQLDMLSHELLAHAEDVTTQIISS--IDHAQKR-HLDGCNKQ 73 
WP_032975697   2 FNRVSLGLNKTSGMVGIIIASLLSVLAVAQIIYWRTEANRIENYTQAVLERSVTLLQQANSLa-AREMKMA-HYPPCSEA 79 
WP_018065621   3 AGRRSI----WIICLVWVFLGGICSLVIAEFIRNHSADEYVDYYGSDVFQNAVSVAETSLTV--LRTLDRS-DNAPCSAE 75 
WP_099997761   5 FDRRWFL---AIMTIVLVAAGALCGTWISRLVVISSDRGQMQIFADQLLNRAVEVFAEADKM--LAVVNAS-PHPFCSDK 78 
WP_125124556   3 LQILRTLHHRIGIYALSIVLTFGALYGAGLGVYYIYAHEKLEDYAESILARSNSLISQVKLIdgLRQEFAV--YEPCSAQ 80 
WP_014748476  99 GLARLRTAAFASRGVREVGVVeEGRVVCTGA-GRLDSPMPLPLPD--MSVGDMRIWYDRlppglDDSARAASRTTVIARG 175
WP_005969766  80 DLAYQRKLVFAAYHIKDIGRLrDDQLICSTLlSDIKTQPRRSVANd-NLKDGTYIYAD------DALITPGSHGPIIGRG 152
WP_014700212  76 YIEKLRVIRWRHPNIEDVTSLkGNDIYCSSFwGEINPPLPITVKSe-TGNNKPELI-GV-----KNNNKTLYNNIGLYQG 148
WP_017456662  77 YLHALRKRLWPYPLIKDIGYVeDGRIICSALwGKYAAPLSLNVFKn-KVSRGSYTWVF------DALIENNITADVVYNN 149
WP_083891039  95 DLDILRKILNQYYYLGDIGRVkNNQIICTVKkGLLKEPINLEDKPy-KSSSDILYWNNQ-----NDLFIDEKEAAIFTQG 168
WP_015583886  74 AIAALREVIWKYASVEDIGIVeNGKLACTANwGRLDKPLPLPAEKy-VVPNGYRIYPGV-----KNYLPYGVVLDMTQQG 147
WP_032975697  80 DLNSLRTMLWEYQMIKDVGRTgARGIICSALwGHLPVPQPLTATQn-IVSRDGARWLL------NLPLTDTINVSAWWRN 152
WP_018065621  76 DLEAMRGVVFAAPYLTDVGRLrDGYLVCTGIwGELATPVKMPPRSqvVGVNAATLWKGA-----RGIAPAGLAVDMSSFG 150
WP_099997761  79 EIMFLRDMLFGTKYLKDMGRVrDGFFHCSAVfGNGKKPMPLIKHDl-ETPDGKLIYANS------RLAISKSTAPIIGIG 151
WP_125124556  81 YQQALRKRLWPYPLIKDIAYVeDEKIVCSALwGKLNAPLSLNMFRn-KVNRGSYTWVF------DAQIEENITADVFYTS 153
WP_014748476 176 PYAVFLDTEQIYDLVLAEPR--VVL-----SMVALGTGQ---VLGVRTRPERAILsd---mvDRFRNQTEPeAIRLG--- 239
WP_005969766 153 NANVVLSSVAFDLLHTPRYA--FSI-----FATDEEKKHfalLYNYSGNAEPGPEpssgdwaQKFVEAPDG--------- 216
WP_014700212 149 HAAVFIARETYESILSTVVD--GYF-----VMTSADKSH---KYFESDPKGYTASg------NSFLrk------------ 200
WP_017456662 150 NFSVTVSPFAFTRFREDSTRwgFNA-----VVGDYNHKQ---HFFRVGNNTSLLE-------NIEHGKVHE-FF------ 207
WP_083891039 169 NTAAFLSTSFLAEVHId-----IQTrngsgGYLYLKDNEy--ILKVFDKIIVADHi------SQTLKKEAS-LYDRLllp 234
WP_015583886 148 NIISFTSSFAFSTFSRQHHG--FNF-----SLTSLNGEH---VFLNNMKSAIGAR------------------------- 192
WP_032975697 153 DLLVIFSPFVFTRFENDAKTthYSA-----MITNSQRDR---RWFTLGPTQALLS-------ATDTSSHYA-WY------ 210
WP_018065621 151 NSVVMTAPTAFARYEDPAER--LAA-----LVLTSDASY---SYQSFGDTEGL---------APLLGSNSD-WYRIA--- 207
WP_099997761 152 NANVVLDPAAFETLKNPAYT--FGV-----MYNPQGVSS---TVGMFGTLDIGKT-------GMELPAGAGri------- 207
WP_125124556 154 NFAITVSPFAFQRFWEEANKmdFDA-----IIGDFKHEN---HFFMIGKNTHLLE-------SIEHNKAHS-WL------ 211
WP_014748476 240 -DRLVVAATARDGTAMALASEPVSVVIETWREQALLMGLPGLASGGLIFWLIVTLVRRGDTMGARIRRGLARGEFRVVYQ 318
WP_005969766 217 -KVLRENSCDPDTGVCISLSATIDRTSTAARLKNLLAICLGALAGGSVGLGWLYYRNRDHSLLYRLNKALAAGEPHLLYQ 295
WP_014700212 201 mFTANASLCSPQWQFCVIAQNAHSGLLLLTTGLLTFVMAAALMLGGFLTFFFFNIFDKRKSLKFRLKKSINKGDMFLEYQ 280
WP_017456662 208 --FITEKSCDAQHDICVVAGVRHSFVFNNNGYILLFLFCVASLVGLFVGALISKNQHENQSLLTRLENAIINKELHFVYQ 285
WP_083891039 235 gSLIHTKHCEENSDICLMTIIKGGGVFQLSYFYIVLISLLSIILGMSVTYVLVVLQGGLTAFLKKFRKAIYAGKIYPVYQ 314
WP_015583886 193 -SSISVSLCSSKFDICTHLTERKQGFLSLSPLLIVLMVGAAFILGAAIVYSILSYLSERRSLEFRLKKAIINQRIYMEYQ 271
WP_032975697 211 --FITKERCNAQYDICVIAGTHPYGLLQARWYTLVLLIALGLALGLLLCTCLALYRKKQTSLTVRLENALKNGDLRVAYQ 288
WP_018065621 208 -QRRVYSRCNDKIDVCVVATYDAPALLKTAPLDFLLVLAGGVSAGACLGLWHAHLYREGRSWRQKLERALNDDRLTVHYQ 286
WP_099997761 208 gDTVYRNVC--RNTACVTVHAEVGRLESSAEPITSIITTFGAALGGAAAVILILLQRNNLSLKARLQHALSQNRLTVEYQ 285
WP_125124556 212 --YFTEHACNNTNDICVIAGTSLPLFFKNNLYILISLFSASLIIGLLIGALYVNNVSHKESLLSRLKHAIENRELHFVYQ 289
WP_014748476 319 PIVRLADGACLGGEALVRWQQRDGSMISPDRFIPVAEAEGLIERLTDEIIEHVFADLGKFLAARPSVWIAINLSASDVES 398
WP_005969766 296 PVVDMADGKVLGFEALIRWEIRKGDFVPPDVFVARAEEAGTATKITIYVLERLIEDMGDTLRQRRDLRININITASDLQS 375
WP_014700212 281 PMVNAIDGEIAGLEALVRWRDDIHGYVSPENFIKISEKIGFYSKISDFVIKTSMREMSVVLKKNKKLTLSINITDHEISD 360
WP_017456662 286 PLYRVKDKSIIGVEVLLRWNDKQMGNIGPDIFIPLAEENGLINKISLYVVEHAIKECGAAL-REKDITLSINVSCSDICS 364
WP_083891039 315 PKVNLCTHETIGVEVLARWNDPILGSVRPDIFIITAEQFQLIRPLTEQLIKQVFRDLNSILESNHNFSVSINVTASLIID 394
WP_015583886 272 PLVCAKNERIVGVEALVRWHDPRYGHISPELFISMAEQLNVYHDLSQLVMEKATSELKTILLADACFTLAINIGKYEIND 351
WP_032975697 289 HIYEIETGRMKGMEALLRWHDSNGDAVSPDVFIPLAEKEGMMSKVTEFVTTQAIAETVELL-EPYDLTLSINISLNDLFS 367
WP_018065621 287 PIVRLSDNRICGAEALARLVDFDGTLIPPDHFIPAAETCGFIGQITRSVVRRAFTDMAAHFAADPDFYVSINVASEDILS 366
WP_099997761 286 PIVDVATGRPVAAEALVRWRE-NGEWIPPDVFIPVAEKAGLINRLTICVIDHVLSDMAASLDANPDFHISINISAADLFD 364
WP_125124556 290 PIYRLKDRQVTGVEVLLRWTDPQIGRIGPDIFIPLAEKNGLINKISLYVVEHSIRECAPIL-LNSDITLSINVSCADICS 368
WP_014748476 399 DRVRGRLDRLRKTHGVAAAQIVLEATERTLIDARRAQSSMRSFRDAGYRLTIDDFGTGYSSLAYLATLPVDGLKLDKTFV 478
WP_005969766 376 PAFMSRMERRLAAADIEPQQVGLELTERTAVDFSKATDGIRRLREQGHRIYIDDFGTGYSSLAYLGELHVDAIKIDKAFT 455
WP_014700212 361 PEFISRLIRVCALYDVEPCQIKLEISERCQLAQKEIQLFAENVAKVNIGLAIDDFGVANSNLAWLTGFRFDEVKFDGSLM 440
WP_017456662 365 KTFYQRLIDTLQQEGVAGKHIMLEITERQSGRIEDIMQSICLYKEHGVLFALDDFGTGYSNLKWLSMLDVDEIKIDKSIT 444
WP_083891039 395 DDFISFLKDEVSQYKFNNKQLVLEITERTTSNREAMARASKIIKKDGYRISLDDFGTGFSNLSWLTTFEPNEIKIDKFFT 474
WP_015583886 352 PLYLDNLLRVLQHKGIRPQQIKIEITERSGEYYKKIAAFSLQAMNRGLRIALDDFGTGSSNLQWLTEVFYDEIKLDKFFV 431
WP_032975697 368 RHYLNFLTQLTHNTGLASNRIMLEITERENATLAHMEAAISLFKQHGFLIALDDFGTGYSTISWLSRLPIDEVKVDKSIT 447
WP_018065621 367 LEFLDFLETETRSHGLSAGQVALELTERSTASQDSLTQAMAAFSRRGYRILIDDFGTGYSNLAYIARMPIAGIKIDRMFT 446
WP_099997761 365 RHFGALLALRLKEANVANNQIALEITERSTANAADAKEAIERLRSRGHKIYIDDFGTGYSSLAYLGELNVDGIKIDKSFT 444
WP_125124556 369 EEFREKLLSTLKDENVAGESIILEITERQSSGTEDIKRSMDLFKGTGIMFALDDFGTGYSNLNWLSLLDVGEIKIDKSIT 448
WP_014748476 479 DGIGSGSAADDVMGHILSLAATLGLDVAAEGVEHQAQADYLIARGVT-YGQGWLYARAMDGNAFCGYVDGHL----PAAP 553
WP_005969766 456 RTVGNDYATVSIIPQIISMAKEHGLDIVVEGVETEAQVLYFRKLGTPlAAQGWFFGKPLCVSDAQALVATVK----KKQS 531
WP_014700212 441 KNLD-NENKEKILYAICSLIKDMGKDIVFEGVEDAEQLKIAREIDAScLIQGWFFYRSLPAKNIENLLINQE----KMA- 514
WP_017456662 445 DSIGTQSINRHILPGLIAMFKDMPRTIVFEGVENEAQHLFLQGNLPEsCAQGWYFSKALAFSEIENLLAQVK----QIDE 520
WP_083891039 475 NSIDTETINSITLDGIISMLNRLDVDVVFEGIEKENELNFIKLNMPNaIGQGRLFGMPQPIDELVAYLSN---------- 544
WP_015583886 432 NGLK-NEYKRAILTSLLDVVCRLNKQIVFEGVESKADFEFVKSFDENaLIQGWYFYRSMPIEKLTALLLPVS----PSHP 506
WP_032975697 448 DAIGTPTLNKTLLVNLIEMLKAMPQQVVFEGLEQRLQVDYLQDNFPGcYGQGWWFSRPIDNQALRLLLTMQAk------- 520
WP_018065621 447 QALDQQAIGAVIVSKVCELAAVLEVTLICEGVETKGQADHLVAIYPDiCIQGFLIGRPMPARQFSRAFPANH----HAWT 522
WP_099997761 445 QTIGTSSVSVSIVPQIIDMARAHGLAIVVEGIETTAQRDYFAALKPKvDGQGWLFGRPASAITIKKALEPVA-------- 516
WP_125124556 449 DSIGTESTNKDILPGLIEMFKNIPKIVVFEGVETDIQYQFLKDNVPGgCAQGWYFAKAVPLSELRSVLTDPCgslpA--- 525
WP_014748476 554 LAN 556
WP_005969766 532 RVK 534
WP_014700212     ---    
WP_017456662 521 GDD 523
WP_083891039     ---    
WP_015583886 507 AAN 509
WP_032975697     ---    
WP_018065621 523 PSP 525
WP_099997761     ---    
WP_125124556     ---    
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