Conserved Protein Domain Family
COG3537

?
COG3537: COG3537 
Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]
Statistics
?
PSSM-Id: 442758
Aligned: 311 rows
Threshold Bit Score: 579.068
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_005506137    1 M--------Kikr-----------------saiSLAILfa--iAGCqsddnpffqggldntlptvpdnskpvcppitdgd 53  
AHX12834        1 MafhpgyvfKrgt-----------------aacALALLcfslpIAT---------------------------------- 29  
WP_011684974    1 M--------Hkl--------------------lVCFLL-----VGS---------------------------------- 13  
WP_011686853    1 Mtfp--gpmRc---------------------vALALLi----AGPa--------------------------------- 20  
WP_012866459  121 lsvdqwnrrvvdlgpwvgqqvtavtvavgatddATTVHvg---------------------------------------- 160 
WP_013376422    1 Ms------qRslrqahrr-------fphglkaaSLALLwp---------------------------------------- 27  
WP_013572760    1 M--------Rks--------------------lLLFVI-----AAS---------------------------------- 13  
WP_014785059    1 M--------Krl-------------------fcLMLLTlgarnVVA---------------------------------- 19  
WP_052359718  172 saigdkvagKtvdriligydqplntgtfrgyfdDIAIS------------------------------------------ 209 
WP_058234607  135 eidlsalsgRrisgaelvv-----ertssgfvdGVMISs----------------------------------------- 168 
WP_005506137   54 csdkpNPekpsvdmgvhkpVEFADMDL---TRYVNPFIGTGN-----LGNTYPGATTPHGMVQLSPNNGANG--WeYISG 123 
AHX12834       30 -------------------ARATTPTP---IDWVNPYIGTAGtg-seYGGTMPLVTTPFGMTNWTAQTRQNHv---SVSP 83  
WP_011684974   14 -------------------LAAAERDP---LASVNPLIGTQKsk-igYGGTMPFVSPPFAMTNWTAQTRQNKi---SITS 67  
WP_011686853   21 ------------------aGADPARSR---ADLPDPLVGTWSmyelsHGNTYPGVFVPFGMLGWTAQMT-EGngW----P 74  
WP_012866459  161 ----dVT------------VRPAPPRPdvlLGWVDTRRGTHSsdrfsRGNTAPVVSVPHGGLFGLPMTDASAgnW----P 220 
WP_013376422   28 ---lwTP------------QALAATPP---SDYVNALRGSNSggaysRGNTFPAAAVPFGFNFWTPMTDANSksW----I 85  
WP_013572760   14 -------------------PMFAQRDA---VSYVNPLIGTEKsa-lgYGGTMPFVTPPFGMTNWTPQTRQNKi---SVTS 67  
WP_014785059   20 -------------------AAAPPRDA---VSYVNPLVGTQKss-igYGGTMPFVTAPFGMTSWVAQTRQNKi---SITS 73  
WP_052359718  210 -------------------AAAPADRL---SDLVDTRRGSNSepgysRGNTFPGATVPNGFNFWTPVTNGNSdgW----L 263 
WP_058234607  169 ----vTS------------RRPRPTRP---VEWVDTRRGTHSsdrfsRGNTFPAAAVPHGFTFVTPMTDAQSsrW----L 225 
WP_005506137  124 YYYH-------DPRLSGFSHTHLSGAGAGDLNDILVMPIN----SRSNYMInegsatLHLEASRFQHKDEQATAGYYKVD 192 
AHX12834       84 YNYA-------DTHIEGFIGTHQPAIWMGDYGYVTLMPEL----DDAKYTP-------QTRRLPFSRKDEAASPAYYAVT 145 
WP_011684974   68 YEYD-------DKTISGFTGTHQPAIWMGDYGYVTLMPQV----GALRTTP-------EGRQLAFSHSDETAKPDYYAVG 129 
WP_011686853   75 YQYF-------RESLIGFMATHQPSAWMSNYGAFSLMPVT----GTLQVQP-------GERASHFSHANEQATPYRYSVL 136 
WP_012866459  221 YRYQmg-----sSSLQAFATSHIPSPWIGDRGVFQLMPSAq---ADPPLd-------RQARALGFDRASEHAGADRYEVE 285 
WP_013376422   86 YDYT-------RSAIQAFTISHMPSPWMSDRQTFQVMPQS----GAVTVDR-------AARGAAFSHANETAKAHHYSVK 147 
WP_013572760   68 YNYD-------DATVSGFIGTHQPAIWMGDYGYVTVVPQV----GPLRIAA-------NERAMPMRHENEKAQPDRYSVI 129 
WP_014785059   74 YNYD-------DKIISGFIGTHQPAIWMGDYGYVTIVPQS----GALRTKP-------EDRAVAFRHEDETARPDYYAVT 135 
WP_052359718  264 YQYN-------ATTVQGFSVSHEPSPWIGDYGQLQVMPMT----GAVKTTP-------DARKSTFSHNNEVAKAHYYKTQ 325 
WP_058234607  226 YSWAehdiapgVTPLGAIALNHQPSPWMGDRTALQFLPVPvlgdEVPVSd-------PGHRNLVFSHGDELARPDRYEVL 298 
WP_005506137  193 LL---D-YGIKAELTASDRVGVHRYTFP-------------------------------RD-----------RKSEIIVN 226 
AHX12834      146 MQagsG-RSIRTEFTATDHCGYLRFLFP-------------------------------KA-----------SRAGVLIE 182 
WP_011684974  130 LRs-aDgARIGAEMTATERCALLRFRFP-------------------------------SS-----------GVARVLVE 166 
WP_011686853  137 LD---A-YKVKVEMTASARGGAFRFTFP-------------------------------KT-----------EEASVLID 170 
WP_012866459  286 L----D--GVSVVMTAAQHAIGLRFRSH-------------------------------TD-----------V-LSVVLD 316 
WP_013376422  148 F----N-SGLQTEIAPTDHGASWQFTFP-------------------------------GT-----------A-SYLLFD 179 
WP_013572760  130 LSagdH-GNLRAELTATTRCAMFRFTFP-------------------------------SD-----------ITARVLVE 166 
WP_014785059  136 LA---D--GLRAEMTGSDRAALMRYRFP-------------------------------KT-----------GDARILVE 168 
WP_052359718  326 L----DtYGITAEMTPTDHAGVMRFKYP-------------------------------AT-----------SESVIVFD 359 
WP_058234607  299 T----H-EGVHIAVAPTDHGALLVAELKgleatphsgadgvtrsdgphgadatagsqrlGDastgestepkpG-LALVCD 372 
WP_005506137  227 TGFKInwdytSDSYLKWd----KKNNR--IEGHRFSd-----G------WAPSQKEFFVMEFDQPIKNVRFayYDKDQkr 289 
AHX12834      183 ATRPG-----IRGYVEVd----QAHRE--VRGYNPDrqdnqlGp----lALPNFKGYFVVRFKQPIKAARV--YKEAA-- 243 
WP_011684974  167 MSRPG-----VPGFAAVd----QKSGE--ITGFNPHrmdahlGp----hKLPNFKGYFVVQFRQAPQDAGT--Y--G--- 224 
WP_011686853  171 AGHGG-------GAVVVh----PEDNS--ITGKNSSg----aG------NSPNFAQYFVAVFDHPITRHGV--WEIPEnr 225 
WP_012866459  317 HLGEA-------VEVRWd----VDGGTlhLDVLLRDt-------------gDGPDHHVHAVFPHVESHT-----LTP--- 364 
WP_013376422  180 TADGIg------GSISId----RTNGV--VSGYTDHs----tG------WGPAPRMFFYAKFSKAITDSLN--VTGQ--- 232 
WP_013572760  167 ASRPG-----VAGGAFLs----PRAGE--ISGYNADrmdshlGp----mKLPNFKGYFVVQFETAPLKTET--Y--G--- 224 
WP_014785059  169 ASRPG-----INGFANVd----LKRRE--ITGYNPHrmdahlGpdkgaaALPSFKGYFVVQFRELPRAGNT--Y--G--- 230 
WP_052359718  360 TIDKVp------GSITVn----NAART--ITGYLDHk---------------gPRIYFSATVDKAIAASGN--V------ 404 
WP_058234607  373 QIGDQ-------GLLRIeplpdGSGAL--LSGYVEGn----pDa-----LERVPRKFFVAVLDTPIRDHGL--DSAG--- 429 
WP_005506137  290 ymd----vpegITeiGN-ETRGkyQYARAYVEFDTaEKGLTVEAKLALSNVEIgkngqSGASLNM-TEVA-GMDFDAVRE 362 
AHX12834      244 -----------PLq-DHnDVEG--DNVGAYVSFDT-GSGEPIEAQVGTSFISM-----AQAQANLdAELP-AWDFDARRQ 302 
WP_011684974  225 -----------Le----kEDAS--TSRGAFAEF---RPGELVEVRVGTSFLSI-----DQARANLrQEIP-EWNFDGVRA 278 
WP_011686853  226 qgrplpnqpavIAa-NSnLRDG--SHVGAYAGFAT-RAGETVTVRIGVSLISV-----EQARRNLeQDMP-QSDFDGIVG 295 
WP_012866459  365 --------------------AD--GVLRGAVTFDA----AAADVLIGVSTIDA-----AQARDNVsR----AGGVDDMLR 409 
WP_013376422  233 ------------------------RAVTSWIRFNT-FAGEKVTMSIATSFISV-----AQAQSNLaQEIG-TKSFDTVKQ 281 
WP_013572760  225 -----------M------EQTGdqASRGAYAEF---APGSSLLMRVGTSFLSV-----DQARENIrREIP-GWDFETAAQ 278 
WP_014785059  231 -----------M------NDAN--AYRGAYVEF---TPGADVEMRVGTSFLSI-----DQARENLqHEIP-TWDFTAAQR 282 
WP_052359718  405 --------------------SG--QGATSWIRFAT-TANEQVTLKMATSYISV-----AQATANLsQEVG-AKSFDTVRE 455 
WP_058234607  430 --------------------R-------GWVRVEG----TRLSMRCAVSFISL-----DQAKHTLeLELPhGISYDEVAH 473 
WP_005506137  363 AATKKWEAELGKIRV---TG--------DEEYKQTFYSALYHAYLGQTIHSDLDGRYRQVhqgr-----------naypD 420 
AHX12834      303 SLKDTWNTKLGLFDI---DGa-------TTDQRQIFYTALYHSLLYPRLFSEHGRYYSAF-------------------D 353 
WP_011684974  279 KLHSAWAAQLGRLEW---EGa-------SDRERTRLYTALYHSLLYPRVFSEYGHYYSAF-------------------D 329 
WP_011686853  296 RAKSAWERQLGKIDV---QGg-------TEAQRRTFYTALYHAVQFPHMLQETDAAGKMVhws--------------pyD 351 
WP_012866459  410 TAADAWRRVLSTVEIhdtDQv-------SADVLRSVGGSLGRIFAYPNTYDEPGPAGpryrspv---------------- 466 
WP_013376422  282 EAQSAWDSVLGKIEV---EGa-------TEDQKTILYSNLYRAFLYPNSAWENVGGTPSYasp--------------yaS 337 
WP_013572760  279 RLRAAWNEKLSAIQV---EGa-------TDAEKSRLYTALYHALLYPRTFSEYGRYYSAF-------------------D 329 
WP_014785059  283 KLRAQWNDKLQRLQV---SA--------SNSEKAKLYTALYHAMLYPREFSEYGRYYSAF-------------------D 332 
WP_052359718  456 ESAALWDTTLGRVRI---EGa-------STDRLTTFYSNMYRAFMYPNNMSEMVGGVRKYfs---------------pyD 510 
WP_058234607  474 AAADAWDELLGRVRIg--EGptadfgprTADRFMTHYGNLYRLFLYPNRASENAGTAQNPawvytspfdelerepdaerT 551 
WP_005506137  421 GntpwgdKIdtlKEsiriadankdGkadfTRYDTFSLWDTYRAVQPLSSILEPDRLADVVLSMLSYAEEewvddkgnlrK 500 
AHX12834      354 D------QV---HD----------G----ESYIDYSIWDTFRAEHSLLTLLAPERIDGMIQALLQNYRE----------G 400 
WP_011684974  330 D------QV---HP----------G----ESYTAYSIWDTFRAENSLLTLVAPERIDGMITALLQDFRE----------G 376 
WP_011686853  352 G------KV---HA----------G----EMFADNGFWDTFRAQFPLLTVLEPRQDGAIIRAMLNAYDE----------G 398 
WP_012866459  467 ------------------dgavrlG----KYSSNNGFWDTYRTAWPLLGLLTPTTAAERADGFVQHATD----------S 514 
WP_013376422  338 Gh-----PV---KT----------G----KVYVNNGFWDTYRTTWPLYTLLIPNKTGEMLDGFVNGYKD----------G 385 
WP_013572760  330 D------QI---HT----------G----ESYTAFSIWDTFRAENSLLTLLVPERIDGMITALLQDFRE----------G 376 
WP_014785059  333 D------TM---HT----------G----ESYTAYSIWDTFRAENSLITLMAPERVDGMITALLQNFKE----------G 379 
WP_052359718  511 N------AV---HD----------G----QMYVNNGFWDTARAVWPLYSLLTPTRTGEMLDGFVNAYKN----------G 557 
WP_058234607  552 Gh-----VV---AS----------G----QVMVNNGFWDTFRTCWPAYFLFTPDYAGELVDGFIEHFRQ----------G 599 
WP_005506137  501 GRLPEWTFKGNeTGMMMGMHATSVIHDVLSKGsLdkrmiDlGFteeernDVKArLIDAMVTDARAATSqg---------- 570 
AHX12834      401 GWMPKWPNPSY-TNIMIGTHADSLVAEAIVKG-F-----R-GF------DWQL-AYDAVRKDAMTPPDgdttrqwrdrep 465 
WP_011684974  377 GWMPKWPNPSY-TNIMIGTHADSLVAEAIRKG-F-----H-GF------DREL-VWKAVYQDAMVPPGgdtsrrwldree 441 
WP_011686853  399 GFIPKWPNPGE-TNVMIGTHGDSVIADAYQKG-I-----R-DY------DVPK-AYAALRKDGTVKGTgvfq-------- 455 
WP_012866459  515 GWVARWSAPGP-VDCMTGTTSDTVFAGLTAQG-V-----P--L------RLDG-AYQSALHHATVPAAdari-------- 570 
WP_013376422  386 GWVTRWSAPGY-ANIMVGTNSDVIFADAYLKG-V-----R-NF------DVPA-AYDSMLRNAATYSSdpar-------- 442 
WP_013572760  377 GWMPKWPNPSY-TNIMIATHADSLVAEAFRKG-F-----H-GF------DREL-AWNAVYKDAMTPPDgdtarrwldree 441 
WP_014785059  380 GWMPKWPNPGY-TNIMIGTHADSLVAEAIRKG-F-----H-GF------DREL-AWKAVYKDAMSPPDgdttrrwldree 444 
WP_052359718  558 GWTPRWSGPGY-IDIMVGTNQDLAFADAYAKG-V-----R-NF------DYRA-AYASMVKNASVYSGsgsk-------- 614 
WP_058234607  600 GWMSRWSSPGY-ADCMVGTSSDIVIADALTHG-V-----T-SF------DVTA-GYDSALRNATSPSPvret-------- 656 
WP_005506137  571 ------vaWIKEYEEQGYVPAqlhDtppdpygahspfKDSWTASYSLEYSMNDWAIAQSIKEVFG------------EDD 632 
AHX12834      466 htpyearaGLTYALKLGYLPS---Dk------------VAESASSTLEESYDDYAVARVAQATGH------------EDD 518 
WP_011684974  442 gtpyearaGLTYYKQLGYIPT---Dk------------IDEAASRTLEDSYDDWCVAQVAKALGR-------------DD 493 
WP_011686853  456 -----arsGIEDYIKLGYVPY---Dh-----------GVRESVACTLEYAYDDFAVAQLAKALGK------------DDD 504 
WP_012866459  571 -----grkGLRPAIFRGYVDT----------------DVHEGMSWTLDNAINDASAARLALALREqttdaa-hrdrlDAE 628 
WP_013376422  443 -----grkGMNRSVFLGYTPQ---Dv------------VGESTSWSLEGYLNDFGIAQLAQALGK------------TED 490 
WP_013572760  442 htpyearaGLTYYKQLGFIPT---Dt------------TDESASNTLEDSYDDWCVAQVARLTGR------------EED 494 
WP_014785059  445 htpyearaGLTYYKSLGYIPT---Dk------------TDEAASRTLEDSYDDWCVAQVAQALGR------------TDD 497 
WP_052359718  615 -----grkGIEVSTFKRYVPT---Dv------------RGEAASWTLEDANNNFGIAQLGRALGF------------TED 662 
WP_058234607  657 -----grkGLHEALFLGWVPT----------------TIHEGMSWSLENALNDYGIAVMSALLAAsccaddprreeyEAN 715 
WP_005506137  633 prYDEFANRSNNWQAQFDFGgsqyQGWFKARDYNGEFI---DaNWvDPVtgrAVgkdwrpdmfNWAFSESNGWQYSFSVQ 709 
AHX12834      519 --YAYFMQRSSNYRLLFNPK----RGFMQARRADGSWA---S-PS-D------------------GWTEGDEWAYLFAAL 569 
WP_011684974  494 --YRFFLHRSLNDRNLFNPA----LGLMNGKTSDGKWA-----PIgGSQ---DTqen----rsVAGWTEGDAWAYTWSPL 555 
WP_011686853  505 --YKIFTARSRNYRNLYDPR----VGFMRGRKSDRSWI---E-PF-DPL---AW---------GGVYTEGNAWQWLWSVQ 561 
WP_012866459  629 --AEYLGRRALGYRSVFHRG----LGFFLGRHPDSTWRvseE-DF-DPA---EW---------GHDYTETNAWGTAFTAP 688 
WP_013376422  491 --AQYYLNRSLNYVNLFSPS----VGFFRGKNANGTWRtsdA-DF-KAN---RW---------GCEYTEGNAWHYSVLAP 550 
WP_013572760  495 --YQFFLHRSLNNRSLYNPA----IGLMNGRKSDGTWA-----PLgSSE---DTlen----rsRAGWTEGDAWAYTWSAL 556 
WP_014785059  498 --YKFFLHRSLNGRNLFNSK----LSLMNGRTSDGKWA-----PIgGTD---DTnen----raVSGWTEGDAWVYTYSMF 559 
WP_052359718  663 --AEYFQNRALDYANLHSPS----VGMFRGKQSSGAWRtadS-AF-KPN---EW---------GYEFTEGAPWHYATPAP 722 
WP_058234607  716 --TEWFGSRAANYVHLFDKR----ISFFQGRDRQGNFRtapE-VF-DPA---RW---------GGDYTETNAWGMAFTAV 775 
WP_005506137  710 HDIHGLIDLMTrfdqtqdpeAKrgELFTERLDEYWSTYPDRna--------gdNQFPvfntGNVGQHVQGNEPDIHVPYL 781 
AHX12834      570 HDIPGTIELLG---------GP--AAAEAKLDAHFR---------------------------DGHNHHDNEPSHHYGYL 611 
WP_011684974  556 HDQTGLIQLMG---------GR--EQYAAKLDAHIS---------------------------GGHNVHSNEPSHHYAYL 597 
WP_011686853  562 QDIPGLMQLMG---------GT--EAFTKKLDELFTTTTTFkvggy---gqviHEMTeakmQDMGQYAHVNEPVHHVAYL 627 
WP_012866459  689 HDGAGLAELHG---------GE--AALGAALDAFFATPETAdptlvgsygfviHEMSeardVRMGMLGLSNQPAHHIPLT 757 
WP_013376422  551 QDGLGLANLYS---------GK--SGLANKIDALFAAPRDYdvgcy---ggviHEMKegydVNMGQYAHSNQPVHHTLYM 616 
WP_013572760  557 HDQAGLLALMG---------GA--AAYDSKLDQHFS---------------------------GGHNVHRNEPSHHYGYL 598 
WP_014785059  560 HDQAGLMQLIG---------GA--DKYAAQLDKHFA---------------------------EGHNVHKNEPSHHYGYL 601 
WP_052359718  723 QDPQGMANLYG---------GR--AQLSSKIDSVFAASRDylpgs---yggviHEMReaydTNMGQYAHPNEPIHHMLYM 788 
WP_058234607  776 HDIAGLASLYG---------GA--DGLEAQLDAFFATPETAradvrgsydtviHEMTeardIREGMLGLSNQPAHHIPFL 844 
WP_005506137  782 YNYVGQPWKGQAAIAAATNVCY-DNTA----DGICGNDDFGTLSAWFVFRALGFFPVNASSGIYEMGTPLFETTSIDVGN 856 
AHX12834      612 YDFMGVPWKTQARVREIAATAY-ANTP----VGILGNEDCGQMSAWYVFTAMGFYPLNPASGEYMIGSPLFTRLALRLGN 686 
WP_011684974  598 YDFAGQPWKTQAKVREIAAAEY-GYDA----GGLDGDDDCGQMSAWLLFSAMGFYPVNPASGEYMIGSPMFRGVSIRLQN 672 
WP_011686853  628 YNYAGQPWKTQRLVRMIEDRMY-RPGP----AGWLGDEDTGQMSSWYIFSALGFYPVNPGQPVYALGSPLFDRATVHLDN 702 
WP_012866459  758 YCFAGRHDDAHRVVVEARDRLF-VGSEi--gQGYPGDEDNGEMSAWYLFAVLGLYPLVPGTGEMVLTPPLLPRVTL-HPQ 833 
WP_013376422  617 YSYAGTPWRIQERVRNILNTQY-QSGLinggYGYLGDEDNGELSAWYLFSAMGFYPVSMGRPEYAIGAPFFTKMTVHLEN 695 
WP_013572760  599 YDFGGQPWKTQAMVRSIAAKEY-AAGP----GGLDGDDDCGQMSAWLLFTALGFYPVNPASGDYMIGSPLYARITLRLAN 673 
WP_014785059  602 YDFAGQPWKTQARVREIAAKEY-GSGP----GGLDGDDDCGQMSAWLLFTSFGFYPVNPASGEYMIGSPIYPRMSLKLAN 676 
WP_052359718  789 YNYAGTPSKTQNRVRDVLTKLYgSGAGn--gGGYLGDEDNGQMSAWYVFSALGFYPARMGSTDYTIGAPLHPKATVNLEN 866 
WP_058234607  845 YLFTGSPHKTHRLVRSLADRLF-TGSDl--gMGYPGDEDNGEMSTWHTFAALGLYPLTPASGTFVLTTPLYEHAEVHLPG 921 
WP_005506137  857 GQTFTIKAKNISRDNIFIQSARFNGKDFNRTYLTHDEIMYGGQLEFVMGDRPNPRWGSLESDLPPS 922 
AHX12834      687 GKSFVVTAKNNAADNVYIQSAKLNGKPLDAPVIRYDQIMDGGTLEFVMGPRPS-DWAKSWRGQATA 751 
WP_011684974  673 GKTFRVIAENVSERNLYVQSATLDGKALNDPVITWEQIQSGATLKFRMGPKAS-RWGGEWRPAPie 737 
WP_011686853  703 GKTFTVEGARKAASDIYVQSATLNGKPLERAWISHAEIVNGGLLRFNLGPRPNQKWGTAg--mP-S 765 
WP_012866459  834 GRDHPLEITAVNPGARYVREVRVDGEVWERVAVPADVLATARHIAFVLSDEPT-GWARDSR--PTS 896 
WP_013376422  696 GANLVINAPNVSDTNRYIQSVTLNGQPYTRNYLPHSALANGATLQFTMGPSAT-NWGSASSDLPPS 760 
WP_013572760  674 GKQLQVEAENNSATNVYIQSATLNAKPLTVPLITWEQIQAGASLHFVMGPRPS-TWASAWRAAPiv 738 
WP_014785059  677 GKTFTVTAQNNSKTNVYIQSASLNEKPLDKPVLTWEQIQAGGTLRFVMGAHPS-QWGSSYRPTAve 741 
WP_052359718  867 GRSFTVEAPGVSDTNRYIQSATLNGVAYTKNYVTHADLLAGGTLSFTMGSAPS-SWGSGANDMPPS 931 
WP_058234607  922 GQRIVIDATGVSEHNTYIRGIRLDGELWDRSWVPTSRLHSGVHIEFDLTDQPT-EFGAAEDLRPPS 986 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap