Conserved Protein Domain Family
UraA

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COG2233: UraA 
Xanthine/uracil permease [Nucleotide transport and metabolism]
Xanthine/uracil permease is part of the Pathway/BioSystem: Pyrimidine degradation
Statistics
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PSSM-Id: 441834
Aligned: 746 rows
Threshold Bit Score: 182.247
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004043715   1 MVvtddSSPSSFVQYGIDDKPPLPTALLLGAQHYLTMVGANIAVPLILAGALGMPADVIPRFVGTFFVVSGIATLMQTTF 80 
WP_013257511   1 MSa---TDQSRALRQTLDRWPSPAALLIFSLQWLVVAVPGVLVVGDLVAVAWGLDGAGRLAFQQRLFLLMGLTQAAQVVF 77 
WP_013330614   1 M----------KFLYGPDERPPLSVALPAGIQWAVISVAYILSFAMLIENIQGGNGAVTVAFIQKVLLITAAALVLQIFA 70 
WP_013840405   1 MN-------KINFKYGLDDIPPLTELLLFGLQWLAIIVPIIIIIGKAIVGLHFSDPLDQVVYLQKLFFVSAVSLLAQVLW 73 
WP_006520950   1 MQ-------KLKLKYALDEVPPYAELLLFSLQWLAITIPIIIIIGQVVAVLHFENTGDQIIYVQKLFFITGLVMLVQLLW 73 
WP_084212066  74 LF--------LTLRYSLDEKLSPLPLALFGLQWLAVALPSLIIIGQVVATVHFAEFSEQILYLRKLSFVVGVTMLVQIVW 145
WP_089610060   1 MT-------QMKFKYGLEDKPPIFQLIAFGLQWLAITVPIIIIVGKIVAGISGGSSEEQILYLQRLFFVVGVSQLVQILF 73 
WP_126306380   1 MN-------QLHLKYNVEDKPPLGRSLLFGLQWMAIIMPMVIFSGKAVAGMQFSDPAQQIVYIQKIFFIIGISILIQVLC 73 
WP_106624011   1 ------------MKYELNDKPGILPMLMYGLQWWIVSLPCVVIMGIIVSQLHYTDVSEQTFYLQKLFGVIGIAMIVQVLW 68 
WP_074175233   1 ----------MRFTYGIDDRPEPASLLIFGLQWLAVSVPAILIIGKVVAGLY---GGPAIPYLQKLFFLTALVLLVQLYL 67 
WP_004043715  81 GNRYPIVQGAPFSMLAPALAviGvaTAadqSGvawqsaLLQLQGAIIVAAVVEVFVGyfGLLGRLRKFISPVVIAPTIAL 160
WP_013257511  78 GHRLPGLVGPASVLLVGVLG--S--VS---SG------PGAVYGAMAIGGLVMALLGptGWASRLGRLYTPPVLASTLML 144
WP_013330614  71 GHRLPLVFGPSAALLIGISS--S--TG---FT------GGVIYGSMAVAAAAGVLIAstGLLAYISRLFTYRVITVVLLL 137
WP_013840405  74 GHRLPLIIGPAAVLLVGIAA--S--QG---SS------TSTIYSSILISGMILLLLSatGLFAKVKKLFTPQVIATILIL 140
WP_006520950  74 GHRLPLIMGPAAVLLIGVLA--G--QG---SS------MQTVYSSIFIGGIILAILSisGLFAQLKILFTTRVVAVILLL 140
WP_084212066 146 GHRLPLVMGPAAVLLVGVLA--S--SG---SS------LSAIYTSVMVGGAALALVSalGMFRALQQLFTARVVAVVLLL 212
WP_089610060  74 GHRMPLIVGPATVLLVAIGA--S--QG---FG------QSVIDTSIVISGLILALLAatGLFARLRQLFTPRVVATILIL 140
WP_126306380  74 GHKLPLVIGPAAVLLVGITA--S--QG---SS------ISSVYTSILVGGLLLAILSssGLLKYVQKLFTPRVVATILIL 140
WP_106624011  69 GHRLPLIIGPASVLLIGILS--T--VS---SG------ISAVYTGIMVGGLILTILAysGLLGRLQFVFTPRIVTVILIL 135
WP_074175233  68 GHKLPLVIGPATVLLIGVLA--S--LD---AG------FGAINASLIVGGLLLAGIAaaGLFEYLKHLFTPRVIAVVLML 134
WP_004043715 161 IGLSLFNAPQVAS--------AT-NNWWLLGLTLALIVLFSQYldtaHPAFKLFPVLLGVIVSYVVAAGL-Svagviapg 230
WP_013257511 145 IAISLVPAMGRMVfdpaaagrAwgASFLFAMALACLILWAQSRl---RGLAGASMLMAGMVVGSAVYYLA-G-------- 212
WP_013330614 138 ISFTLIPVITPMFissg-vssGSlYTLIFGLAVLAGMYLAQRFg---GRIIRATLFLWVLIPGTLIYSLIfA-------- 205
WP_013840405 141 IALTLTPMIINLIfas--qqvAPvQNLCFVFIFVLGMFWANQRl---TGLWKTTLIIWAVIIGTALYMLLfP-------- 207
WP_006520950 141 IAFTLTPTIMNMIlpaagskvSAlLNILFALGMVLLMFVANRFl---TGMWKSTLIIWAMIIGSLAYSVVsP-------- 209
WP_084212066 213 IAFTLAPAIRDLIldtt-rpgSPfGRLVFALVLVLVLFGLQQKl---TPLWRSTLVVGGLVVGSLIYPLFfQ-------- 280
WP_089610060 141 IAFTLTPMILNLItstf-gtiSPfENLVFSLLLLLGIFAANKLl--aPGFWKSTLLLWVIILGSIIYLLIfG-------- 209
WP_126306380 141 ISFTLIPMILQLIfaa--aqiSPlANLLFALVFLLLLFLANKSl---KGIWRSTLIAWSMVVGSIVYVVLfP-------- 207
WP_106624011 136 IAFTLTSVILKLVlgd---avRAlFNMFFTLVMVLALVIGNKLl---RGIWKSTTVLWGIVGGVLVYYGVfG-------- 201
WP_074175233 135 IAFTLAPVILNLItdgg-gtvPAtHAFLFALAFALILFIANGFl---KGIWKSTLALWAIILGTLAYVVLfG-------- 202
WP_004043715 231 aagYVNl--Q-TVIEAPALMP-I----Y---PLQWgfaggagtttvslpvvgsvafGIP---Q-FTTSFIIGMLAGVAAS 295
WP_013257511 213 ---M-----------GPWPGL-PpasgQgltLATF---------------------AGPs-lS-FDLPVVLAFIICSLAL 254
WP_013330614 206 ----YNp--T-EITYYGLSGI-T----T----------------------------GFPtgfT-VEPGVLISFLICYLAV 244
WP_013840405 208 ----QYtgiSyH-QNFSPISSfF----R-----HV---------------------SLDf--S-LDPSVLISFLICFLAL 249
WP_006520950 210 ----SSvviD-A-GNYKWLASfI----N-----DI---------------------SFEl--S-LEPGVLISFLVCFLAL 250
WP_084212066 281 ----HAglsE-Q-PSLPFAAGfW----Q-----NL---------------------TWPp--S-FEPGLILAFLVCYLAL 321
WP_089610060 210 ----EHfyiG---EDTKIIAGfF----H-----SL---------------------SFDf--S-VNPGVLLSFLICFLAL 249
WP_126306380 208 ----QAvpvM-N-STGKIFSGfF----Q-----DF---------------------NTAf--S-LDFGTLTAFIICFLAL 248
WP_106624011 202 ----LPmlpS---TGVEIILEqA----T-----VL---------------------NFPl--N-FEAGTILAFLFCYIAL 241
WP_074175233 203 ----AVplpP---EGTALLAF-P----G-----DL---------------------LAPl--AvPDVGVLAAFLICFLAL 242
WP_004043715 296 MVESFGDYHAVARLSGVgAPSERRINHGIGMEGAMNVFSAVMGGSGSTSYSENIGAIGLTGVASRYVVQVGAVVMLVMGF 375
WP_013257511 255 VANELGTLESLGRMMDL-PDMEKRVGRSVAVGGLGCLAAGLLGVLGPVTYSVSPGVVLATDNASRWSLLPVALALVLLAF 333
WP_013330614 245 IVNDIGSIRSIAEVIEE-RSMQGRYKRGIIATGIANIASGLFGVIGGVNYSISAGMILETRCASKWTLVPAAIIMAAIAF 323
WP_013840405 250 SINDLGSIQSIGEIIRP-DNMEKRITRGVSFTGLGNILSGLFGVIGPVNFSLSPGVIASTGVASRFTLIPTAFGLLLLSF 328
WP_006520950 251 SINDLGSIQSVGELLKP-ANMPQRITRGITLTGLANMLSGFLGVVGPVNFSLSPGVIASTGVASRFTLIPTALGLLVLSF 329
WP_084212066 322 AVNDLGSIQSLDGMLRP-GDMAGRLRKGMTITGLSGCAAGLLGVLGPVNFSLSPGVIAASGCAARRALWPAAVVMIGLAF 400
WP_089610060 250 SVNDLGSIQSVGAMLHT-DHMEKRVTRGITLTGLLNVGAGLFGVVGTVNFSLSPGVIASTGVASRFTLVPTALGLMILAF 328
WP_126306380 249 AINDLGSIQSIGDMLYA-GDMPKRITKGITLTGVFNIFAGFLGVIGPVNYSLSPGVIASTGVASRFTLLPAGIGLILTAF 327
WP_106624011 242 IVNELGSIQAVGHMLQA-DHMDRRTTRGVGIVGVVNMLSGLFGVIGPVDYSMSPGVISATGCASRYTLLPAGVGLILCAF 320
WP_074175233 243 AINDLGSIQSVGGLLAA-DKMGERVNRGVTVTGLGNALAGLTGVIGPVNFSLSPGVIAATGCASRFALVPAGVALALMAA 321
WP_004043715 376 VGYFGQLIATIPDPIVGGLYVAMFGQIVAVGLSNLK-Y-VD--LDsSRNVFIVGVTMFAGL---AVPA-YMgnvgsaaaf 447
WP_013257511 334 WPQGMGFFQLVPQPVAGAVLFCLMALTTYAALAVLEgGaCA--AD-RRSGLVVGASLVAGAiisFLPEdAR--------- 401
WP_013330614 324 LPDLVALMTLVPSVIIGAVLIYVLAAQFSAALYVFFkEtAGreFE-YESGIIVGLPVIIGTmisFIPSeIA--------- 393
WP_013840405 329 LPSTIAFIGSIPSAVTGSVLIYIMCAQISSGLLVAFnTtGG--FK-FENGLIMGLPLMLSIiisFLPPnIA--------- 396
WP_006520950 330 LPVAIAFMDSIPSVIIGTVLFYVMCSQVAAGLMMAFsS-RE--FN-FDSGLVIGLPVMLGVviaFLPAeVL--------- 396
WP_084212066 401 LPGTLSVVRAVPPTVVGAILLFILSAQVAAGLMSLYsQkET--VE-FEHGLVVGLPVLAGTiisFMPSsVT--------- 468
WP_089610060 329 LPKAIAFMGSIPSVIIGTTMIYIMCSQIAAGLMTAFhAqEG--FA-FEDGLVMGLSLMLSIlisFLPQdVL--------- 396
WP_126306380 328 LPPVINVIGIIPSAVIGSTFIYTMCSQLAAGLLLAFhSmKN--FR-LEDGLILGLPLMLGVlisFLPTdAL--------- 395
WP_106624011 321 FPSVVGMLVTIPGVVMGAILLYLMATQLAAGLQMLVrEkAI--TD-FDSGVVVGLPLMVALllsFAPEkVL--------- 388
WP_074175233 322 SPLAIGYLGSIPGPVIGVVLAYVMAAQIAAGLMLGQeSsAV--RT-FDEGLIIGVPLLLGTvvaFLPAaVA--------- 389
WP_004043715 448 regmrqvalvgpvlgtQLVADTVFVIGSTGMAVGGLIAFFFDNTIAgTRAErgleeweD 506
WP_013257511 402 ----------------QAMHPYLRPVLGNGFVTGLLLAMILDRLLPrPSAA-------K 437
WP_013330614 394 ----------------EAFPPLVRPVIANGFVMGVIVVMLLEHVIfrKKKE-------P 429
WP_013840405 397 ----------------NSFPSSLRPIMGNGFVIGVLSVLILENVIyrRRNS-------E 432
WP_006520950 397 ----------------NTMPASLRPIIGNGFVAGVFTVMFLEHIVyrSK---------- 429
WP_084212066 469 ----------------ETLPGLTRPIAGNGFVAGVLLALWLEHVVfrRKAA-------Q 504
WP_089610060 397 ----------------ITFPLFLRPVLGNGFVVGVISVLIMDHIIfrKK---------- 429
WP_126306380 396 ----------------ASFPLWLKPVLGNGFVVGVIAVLIMEHIVyrPLKN-------K 431
WP_106624011 389 ----------------NLIPYLFKPIVGNGFVMGVITVLIMEHLIfkKK---------- 421
WP_074175233 390 ----------------AGFPATLRPLIANGFVVGIVAVLVLEHLVyrRRSE-------N 425
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