6OAX,1QVR,6EM9


Conserved Protein Domain Family
ClpA

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COG0542: ClpA 
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440308
Aligned: 635 rows
Threshold Bit Score: 811.234
Created: 9-Feb-2022
Updated: 24-Feb-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6OAX_A         1 Mr-------LDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPq 73 
AEI51511       1 Mi-------STQLNDELIRAIQIAQAIAKEHQQGVYAPAHLLKGLLHNDVG-LGALLVGWEIDINYLRDWADYRIEKLPk 72 
WP_085413822   1 Ml------pSFLLSEAVQTALHVSQSLAREYRNERYSAAHLLRALVHNDSA-GATLLTSLHKDVPYLREWAEVRMEESTr 73 
WP_015813027   1 -----------MQTEALRYAITVAQSLAREYRQERFGPAHLLMGLLHNDVG-LASELVMAGKDVPYLRDWAEVRLEESPk 68 
WP_128151527   1 Mmq-----kEAVFHEELYLALEIAKKYAIENKNVEYGAAHLLKAILHRDLS-LLKELEAMKKDVFFIEEWAEVRIDDAPk 74 
WP_013668058   1 Mn-------IVNISDTLQMAIRMAQSLAREYQQEAYTPAHLLRGLMHEEIG-VQQFIASLGKEVDYVIEWAEVRMEGLGk 72 
WP_076380021   1 Mn-------ILFANDTVKEVLHIAQAIARENYHATYGAPHLLRALMHKETG-LHDFLHSLEKDPAYFIEWAEVRMEDFPs 72 
WP_012792476   1 Mn-------ISNSNESVKIAIRIAQSLAKEYHNGEITPAHLLKALMHKEVS-LYSFLTAINKDAAYIAEWAEVRIEALEk 72 
WP_040199606   1 MdnrqlrslLERLNNHCVNALEGAAAFAATRGHGEVTIEHLCVKLLEQGGGDFDRALHRFGVDLDAFWQALLAALARRS- 79 
WP_013870865   1 Ma-------DYALSSKLKEALHIAQAIAKEYSNKQYSSAHVLKALMHKSIG-MIKYLESIDQDGYYVEEWAEVRLESLPk 72 
6OAX_A        74 vEGTGGDVQPSQDLVRVLNLCDNVAQ-KRGDNFISSELFVLAAL-ESRGTVADI---LKAagATTANITQAIEQ-MRG-- 145
AEI51511      73 sARGTLDMRPDPKTVAALEVADIIRL-KLGDSSLSPLAVLIAITrPEVAYTKDQ---LKSfpITETELLTFALQnI-Qae 147
WP_085413822  74 vAIPPDEPSGDTSVERVMEEADVVRV-RLGLDKVEPICVLTALTkPGLGFPSEQ---LRSlpLQERDLLGLYLNeM-Kpl 148
WP_015813027  69 sMKVPEVPPADNLASAALELAELIAL-QLNID-TDPLCTFAALLkPGVGFSSDQ---LKSlpITQKEVLGLHQApM-Sgd 142
WP_128151527  75 aGRAT-QPEPDESIDKVTAEADEIRD-ILGREEVDLYCVIVALAtPGVGFSFDQ---MKSfpVVRDELLTEVETaLpse- 148
WP_013668058  73 vGRLPDIISPTDESVRVLEEADVIRI-KLGLPLITPICVLAAICkPTVGFTPDE---LRSfpIKEAEIFDFYLGqT-Sla 147
WP_076380021  73 tMSLPETIEQAPEIEDILEEADDIRV-KLGLDEVTALCVLTALVkPHVVFTPAQ---LKSlpLREGEIIASLKGtS-Enn 147
WP_012792476  73 tAQVTDEVKGSAAIASVFEEADHIRL-KIGADLINPVCVLAALCkPTVGFTVEQ---LKSfpLKEREVLDGFMRdE-Eir 147
WP_040199606  80 -AGPAGKPLFGASLQQWLERAWLAASlHYHTDRIHSAALLDALVtLAPALPEETfalLDN--VSPEILRKEFGR-PGD-- 153
WP_013870865  73 tNKVPENPSADDSVEAVLYEADNIKL-KLGLEEVTEHCVLIALCtPGVGFSFEQ---LKSfsLTPNEIIDNIg--V-Ked 145
6OAX_A       146 G--------E--------------SVNDQGAE--DQRQALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNN 201
AEI51511     148 Tt------lSpas---------dePSRAGGGN--ASFQALLKYCVDKTALARQGKLDPIIGRDKETRTMVEILGRRSKPN 210
WP_085413822 149 TpgdgaktvTpgg---------taTPVTAAEG--ATAGVLQKYCTDKTALARGGHFDPIVGRERELRMMVEILGRRSKPN 217
WP_015813027 143 Na------iQat----------nhQSTTPTAP--VAAGFLEKYTSDKTQRAASGKTDDIIGRDREIRQMAEILGRRSKPN 204
WP_128151527 149 ----------------------ndSDKDGKPP--VSVKYLYKYCKDKLVQARKNPKN-IVAREQEIKEIVEIICRFSKPN 203
WP_013668058 148 Qs------vTa--------------TGENAQA--TSGASLAKYCIDRLNKAQDGTTDPVIGREMETRMIVEILCRRTKPN 205
WP_076380021 148 --------aTpln---------gvNGKSEQHY--GSDSALHKYCVNKTALAQSKTIDPIIGREKETRMLIEVLGRRNKPN 208
WP_012792476 148 Qv------vApa-----------tQQGEKAVI--NTTGALYKYCIDRLTPAREGKTDPIIGRDRELRMMMEILCRRTKPN 208
WP_040199606 154 D--------SaeeqggqdsattmaSLQTKTSPggEASSFLARFTVDITARAAAGDIDPVLGRSREIRMMLDILARRRKNN 225
WP_013870865 146 g------tvSapa---------gtTSKKQNKA--VGTGTLSQYCIDKTSGASNNELDQISGRESEIKMIGEILGRRSKPN 208
6OAX_A       202 PVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKqEGNVILFIDELH 281
AEI51511     211 VIIVGEPGVGKTALVEGLARLIIAGQVPAHLQKAALFQLDMGALIAGASYKGEIEDRLKNIIAEVKRh-ERALLFIDEIH 289
WP_085413822 218 VMLTGDPGVGKSALIDGLAQLLITGLVPGWLKGATLLELDPGALLAGASYKGEVEDRLKNVIREVKAf-EKCILFIDEIH 296
WP_015813027 205 VILTGEPGVGKSALVEGFAKLIAEKKVPQLLQNARLLELDTGALVAGAAYKGEIEERLKGILNEMKGf-DKAILFIDEIH 283
WP_128151527 204 VLLQGYPGVGKSVLIDGFVNLIVKKQVPDKIQKTRVYELDLGTLIAGASYKGEIEDRLKKILQELKTy-PQAILVIDGIH 282
WP_013668058 206 VILMGEAGVGKTALVDGLAQDILQKRVPSSLEQAQLFELDLGALIAGASYKGEVEDRLKNILKEIRAf-SKAILFIDEIH 284
WP_076380021 209 VIITGEPGVGKTALVDGLAYEIIAGNVPLHIQHAVLLELDMGTLMAGASYKGEVEDRLKKIITELKKl-DKAILFIDEIH 287
WP_012792476 209 VIITGDAGVGKTALVDGFATDIVAGEVPEQLKRTQLFELDLGALIAGASYKGETEDRLKNILKEIRQf-DKAVLFIDEIH 287
WP_040199606 226 PIVVGEPGVGKTAVVEGLALRIAAGSVPDSLRKVRLLALDLGLLQAGAGVKGEFEKRLKNVIEEVKAsPEPIILFIDEAH 305
WP_013870865 209 VLILGDPGVGKTVLFNGLAYASVNNNVPEHLKSARIYELDFINLVSGAGYKGEIEDRFKKVIEEIKQf-PKAILLIDEIN 287
6OAX_A       282 TMVGAGKADGAMDAGNMLKPALA-RGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELH 360
AEI51511     290 VLMDPQS--GAMGLVNLLKPELA-RGELTVIGATTLDEFRKFMEPDEAFSRRFELVRVDEPDETTASRMVGRVVPLFEEH 366
WP_085413822 297 VLLDPKGGAG-GGAANLLKPELA-RGELTLIGATTRDEFRKLIEPDQALSRRFELLNVDEPPVNVAERMIRGLVGLYEKH 374
WP_015813027 284 MLLDPKGSIG-AGVAQLLKPELA-RGELTLIGATTPEEYRKYIEKDEAFSRRFEILHVEEPDELTATRMIEHMLPVYEAH 361
WP_128151527 283 VLLDKNSD--NAGISSILKSELSgNGGLTLIVTTTVDEYTKKIEKDEGLSGMFEVLKVEEPDEEQAFRIIKSALVSYLAH 360
WP_013668058 285 TLLDAKGPFG-NGLGNLLKPALA-RGEITVIGATTRQEYRKFLEPDAAFIRRFERVVVEEPDSYVATEMVKQASGRYTEY 362
WP_076380021 288 QLLDSKGALGS-GTANLLKPELA-RGAITVIGATTSEEHRKIIEPDQAFSRRFEVLAIYEPDADTCYKMIEFLIPRYEAH 365
WP_012792476 288 TLLDSKGPLG-AGIGNLLKPELA-RGEITVIGATTLEEYRKYIEPEQAFNRRFEVLQIGEPTEAAAIRMLEKLSERYATH 365
WP_040199606 306 TLIGAGGEAGLGDAANLFKPALA-RGELRTIAATTWGEYKKYFERDAALARRFQPVKVEEPSQEDAIAMLGGLRDLYQQH 384
WP_013870865 288 NLTDKN-Q-GNQGLANLLKSELV-KGELTVIGTATNDAFRKYIEVDEGLARQFETVRLIEPSEDEAYRMIKNTISYYTDH 364
6OAX_A       361 HHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDea---s 437
AEI51511     367 HQIKVGQGTVVETVRLARRYIKDRRLPDAAIDLIDRTMAAMKLMTETTQQEIDLLRTELTELR-------EE-Hag---g 435
WP_085413822 375 HQLTVDSDVVPECVRLAKRYVKDRRLPDAALDLLDRTMAAIRTVTELAGSDLSQFDKALTEIN-------ES-Els---p 443
WP_015813027 362 HGLKVSVGTAAEAVKLAKRYIKDRRLPDVALDLLDRTMAAMRLMGEVSETEIGVLQTDLDTLMA------ID-D------ 428
WP_128151527 361 HEIKVTDDSITESIRLAKRYLKEKSLPESALNLLDRTMSVIKTAGVSFLKEKEGLESKLDHIK-------EK-E------ 426
WP_013668058 363 HGISIRADVPAECVRLAKRYLRDRRLPDAALDLLDRTLAAIKLMNDSSIAVLDDIEERLRRLE-------NL-Qvn---e 431
WP_076380021 366 HHIKIAPDAIAECVRLSKRYLKEKCLPDAALDLLDRTMSAIRMLDETSAKELQQWKDKYEALKA------ES-Neg---e 435
WP_012792476 366 HQLQIRPAALADCVHLAKRYMKDRRLPDAAFDLLDRTLAAIKLMNDTSAKVLVELQQALQALQ-------TT-Et----- 432
WP_040199606 385 HGILITDEAVTAAVHLSARYICGRQLPDKAIDLIDTAAARLCMAQSVVPAEIDADRERAAFLQGRLSALIAEKAqgvsfd 464
WP_013870865 365 HKLTIDSETINEAIRLAKRYNKERSLPDSAIDLIDRTMSAAKYMIETSVDEIETIKQHLEALK-------EDTEft---e 434
6OAX_A       438 KKRL--DMLNEELSDKERQYSELEEEWKAEKaslsgtqtikceleqakiaieqarrvgdlarmselqygkipelekqlea 515
AEI51511     436 DPILynQELRWFERQLRHRLSPILLgqLEEDtqlaqmelpeav---------------------------aelltellir 488
WP_085413822 444 EERL--DDYRWFDQQLQQQISPVLMgqWEDPvdptelvtpdty---------------------------lpyltakltr 494
WP_015813027 429 AERL--HELKWFARQLPNRLSPLLTgqLNENeatdletsegi----------------------------hnqltsklsa 478
WP_128151527 427 GDHK--QDLKWYYEDLKRKSQYLLIqeKESQveienlsqedl----------------------------fmylkstlek 476
WP_013668058 432 VERE--EAYVWLGRQIQNQISPILLaqLSEipqevngtdal-----------------------------vdrlksqias 480
WP_076380021 436 QASL--RDYKWHYQLLQNMVSPILWgsLQEQpdisaiesvael---------------------------qqltektfae 486
WP_012792476 433 PPSL--SDYQWLYTQLQDKVSPVLLgqLQDEtavagfetnaqy---------------------------qeyldrtlta 483
WP_040199606 465 DTLL--KKVGDELEEVQRRLWMAEKKWAAEGelirqvrgqreelpada----------------gdccgkvvalrraagq 526
WP_013870865 435 EELL--KEQTWQYALMKNRLSYLLFdeLGDDnhfedvktskag---------------------------fkamesmlnq 485
6OAX_A       516 aTQlegk---tmrlLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIRRSRAGLA 592
AEI51511     489 lQTlg-------gqRKETVETHDVAAVVAHKTGIPLGKLQSTEREKLLQLNEHLKKRVVGQDHATKVIADAILENRSGLS 561
WP_085413822 495 lHEla-------daRQAHVTKTDLAAVVAYKTGIPMGKVQEREKEKLLAMEDHLRQRVVGQDHALKALSDAILESRSGLQ 567
WP_015813027 479 lREla-------trRSDTIGKNDVAAIISHKTGIPLGKLQSSERDRLLGINEVLKKRVVGQDQAVKALSEAILESRSGLI 551
WP_128151527 477 lNEaa-------lsKKEHIEPIDLAAVVAQKTGIPLGKLHSEEKDKLQNMEEILKKRVVGQDYAIQVITEAVLESRSGLS 549
WP_013668058 481 lRTha-------sqRPDELTKENIAAMVSYKTGIPIGKIRAGEQERLMHMQDFLRARVVGQDHALDAVADAILESRSGLN 553
WP_076380021 487 lDTlk-------eiKRDTVGKQELAAVMAAKTNIPIGKIQAKEKEKLLNMETALQRRVVGQDHALKVLSDAIVQSRSGIH 559
WP_012792476 484 lQQra-------tiPVQEVSGQEIAAIVSYKTGIPLGKIQAQEREKLLNMVPFLKNRVVGQDHALRVVADAILESRSGLN 556
WP_040199606 527 tRAqlkeaqgenpmLQAEVNGEAIAAVVSEWTGVPVGRMLRDELEALLKFEEALAQRVIGQDDALAVIGETIRSAKASLR 606
WP_013870865 486 lHEva-------sqEKTSINKNDVASTIANKTGIPTGKLQADEKERLLNMETVLQRRVIGQDHAISVITSAVLESRSGLS 558
6OAX_A       593 DPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYS 672
AEI51511     562 RPGQPIGSFFFSGPTGTGKTELAKTMADFLFNDEKALIRFDMSEFKEEHSAAVLYGAPPGYVGYEEGGLLVTKIRQQPFA 641
WP_085413822 568 KAGQPIGTFFLLGPTGTGKTELSKSLADFLFNDEHAMIRFDMSEFKEEHAAALLYGAPPGYVGYEEGGLLVNRIRQQPYA 647
WP_015813027 552 KAGQPIGSFFLLGPTGTGKTEIAKALADFLFNDESFLIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGLLVNKIRQKPYS 631
WP_128151527 550 KAGQPIGSFFFLGPTGTGKTELAKSLADFLFQDEHAIIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGLLVNKIRQKPYS 629
WP_013668058 554 KKGQPVGSFFLLGPTGTGKTELAKSIAAFLFNDEKAMIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGLLVNKIRQHPYT 633
WP_076380021 560 KPGQPIGSFFLLGPTGTGKTELAKSIAELLFNDEKAMIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGMLVNKIRRQPYS 639
WP_012792476 557 KKGQPIGSFFLLGPTGTGKTELAKSIAEFLFNDEKAMIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGLLVNKIRQQPYT 636
WP_040199606 607 NPAAPLGVFLLAGPSGVGKTETARALAQQLFGGERFLVTINMSEYQESHTVSQLKGSPPGYVGYGEGGILTEAVRQRPYA 686
WP_013870865 559 KPGLPVGSFFFSGPTGTGKTELAKSLAEFLFQDENAIIRFDMSEFKEEHSAALLYGAPPGYVGYEEGGLLVNKIRQKPYS 638
6OAX_A       673 VILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQE-RFGE----------LDYA--HMKE 739
AEI51511     642 IVLFDEIEKAHPSVFDLFLQILDEGTLHDRLGREGDFSNAIILFTSNIGSEWIAG-QFGQg------------Qi-PASN 707
WP_085413822 648 VVLFDEIEKAHSSIFDVFLQIMDEGRLHDKLGKEGDFSNALLIFTSNIGSEWISQ-EFQQg------------Rl-PSSQ 713
WP_015813027 632 VVLFDEIEKAHPSVFDLFLQILDEGKLHDRLGKEGDFSNAVILFTSNIGQEHIIR-EFNKg------------Gv-PQSS 697
WP_128151527 630 IVLFDEIEKAHSSVFDVFLQIMDEGKLHDRLGKEGDFSNALVLFTSNIGSQFIVK-SVNEg------------NglPTSN 696
WP_013668058 634 VLLFDEIEKAHPSVFDTFLQILDEGHMHDRLGREGDFTNALILFTSNISSDWISS-RFSMg------------Ei-PEKA 699
WP_076380021 640 VVLFDEIEKAHPSVFDVFLQIMDEGKVTDKLGKEGDFSNALILFTSNIGSQFIVE-KFEQq------------Vi-PTSR 705
WP_012792476 637 VLLFDEIEKAHPSVFDTFLQILDEGHMHDRLGKEGDFSNSLILFTSNIGSEQISA-QMNRg------------Ei-PASQ 702
WP_040199606 687 VILLDEVEKAHPDVMNLFYQVFDRGFMRDGEGREIDFKNTVILMTSNLGAEEINAlYSSLdeegdesqtaPTLS--QLGD 764
WP_013870865 639 IVLFDEIEKAHPSVFDIFLQILDEGKLSDRLGKVGDFSNAVILFTSNIGSQHIVD-SFDQg------------Ii-PKSN 704
6OAX_A       740 LVLGVVSHNFRPEFINRIdEVVVFHPLGEQHIASIAQIQLKR-LYKRLEER-GYEIHISDEALKLLSENGYDPVYGARPL 817
AEI51511     708 DILDLMTKHFRPEFLGRLtEIIPFSPITESAVLNIFNIQLKP-LIVLLEKQ-GITLNIDDEARKALALEGFTPKYGARPI 785
WP_085413822 714 QLMERMSGKFRPEFLARItEIVPFSPITEQHVLHIFDIQLRQ-LTDSLHRQ-GIRLELDAAARQQLAFSGYTPQYGARPL 791
WP_015813027 698 DLMEIMAGYFRPEFLARLtEIVPFAPISEENVVKIFDIHVRS-LTDLLDKQ-GISLKLTPEARKSIAMQGFTPRYGVRPL 775
WP_128151527 697 QLLEIMSNNFRPEFLGRLtEIVPFGPISKDNAMGIFEIHLKKeLLDLVKGI-NINLTISESAKSFLVDNGFNATYGARPL 775
WP_013668058 700 ELLDRMTAYFRPEFLARLsEIVPFAPIQGAHLVRIFEIQLES-LRTALEQQ-GIGMQISKEAIEMLATQGFNPKYGARQL 777
WP_076380021 706 ELMDIMARNFRPEFLARItEILPFAPVNEAMAVNIFNIQLTS-LLNPLHRL-GIALNITDDARKQLALSGFSPQYGARQI 783
WP_012792476 703 QLLEIMSPYFRPEFLARLsEIVPFAPISEQNVVRIFEMQLNS-LTQALHQQ-GIRLQVEAEAARMLALGGFNPKYGARQL 780
WP_040199606 765 VIRPALTRHFAPALVARM-QVVPFRPLSAEALHNIVALKLDE-AAQRLHAAhGIELRCAPEVLEFLAERCRQPQTGARFI 842
WP_013870865 705 DLLEIMGSYFRPEFLGRLtEIIPFSPITKENVVKIFKIQLQG-LLKALGKQ-DISLEISNDAMEHLAIKGFTPKYGARPL 782
6OAX_A       818 KRAIQQQIENPLAQQILSGELVPGKV--IRLEV-NEDR--IV 854
AEI51511     786 RGVIRNRIRRPLSRMIVAGEIGKGST--VTLKL-GKDGe-FD 823
WP_085413822 792 AGVIRNRLRRPISRMIIAGQIHAGEW--LRVTA-RPDGe-LS 829
WP_015813027 776 KGVIRNLLRRPVSRMIISGEAGKGSV--IEIST-GESGe-VV 813
WP_128151527 776 KGIIRSELRRPMAKKIISNEIKEGDT--VQVDL-DDNN--LK 812
WP_013668058 778 ATVIRNELKRPISKLIVSGALRKGLS--VHIAK-HVEQtdLL 816
WP_076380021 784 SGVIRSQLSRPISRMIVNEEVQKGHT--IVVSL-DAEGq-LQ 821
WP_012792476 781 SGVIRNELRRPISRFIIAGDVKKGQE--ISVGR-HTDEekLE 819
WP_040199606 843 NALLEQRLLPGIARNLLGYMAEDDMPdiLTLEMdERGE--VA 882
WP_013870865 783 RGVIRTDLRSPLSRMIISGDITKGAK--VSLKL-NKEKe-LE 820
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