4GQU


Conserved Protein Domain Family
HisB2

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COG0131: HisB2 
Imidazoleglycerol phosphate dehydratase HisB [Amino acid transport and metabolism]
Imidazoleglycerol phosphate dehydratase HisB is part of the Pathway/BioSystem: Histidine biosynthesis
Statistics
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PSSM-Id: 439901
Aligned: 614 rows
Threshold Bit Score: 116.668
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4GQU_A        27 ESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALgDKRGIRRF 106
ABK78642      12 ETEVSVSVLLDGTGSTTVNTGQPFLDHLVSSLGKHAMFDIDLKASSRDGIV-HHLVEDVAITLGGAIDKALgDRSGIMRF 90 
ALI34998      18 EVSIVIKINLDGKGNSNVNTGIDFLNHIVVSFSKHSKIDIDLKAKSEDGIK-HHLIEDTGIVLGQAIDKALgKRENINRF 96 
CUR52680      14 ETEVIVEVNLDGTGKISVKTGLPFLDHLITSLSKHAMLDLKLNAKSMDGID-HHLIEDAAIALGNAMDQSLgNRVGIVRF 92 
WP_012800790  19 ETAIRLDLNIYGQQKLKINTGLPFFDHMLIQLALHAGWDLNLEANGDLEVDDHHLIEDVAICLGQALQQAWrEQESITRY 98 
WP_075055341  19 ETSVTVEVNIDGDGNTKVKTGLPFIDHLITSIGKHSMMDITLAGKSNDGIV-HHLAEDVAIALAQAIDKALgDRARIVRF 97 
WP_048106155  14 ETSVSITINLDGTGKTTINTGIKFLDHLIGSFGKHSMMDLVVKAKSRDGIE-HHLIEDTGITIGSAIDKALgNRSGITRF 92 
WP_048188617  14 ETSITVQVNLDGSGKTSTNTGIDFFDHLITSFGKHAMLDIVVKAKSNDGIT-HHLIEDTGIAIGNAIDKALgNRTGIVRF 92 
WP_086907056  14 ETTISVSVNLDGQGNTSIKTGINFVDHLITSFGKHGMMDLKVNAKSNDGIE-HHLIEDTAITIGQAIDKALgSRKGITRF 92 
WP_103287792  16 ETSVEVEVDLDGNGLYSVETGIRFLDHMIASISKHSLIDIRLKGVSKDGIR-HHLIEDVAITLASALDKALgSRDGIERF 94 
4GQU_A       107 GDAFIPMDETLAHAAVDLSGRPYCVHTgEPDhlqhTTIAGSsvpYHTVINRHVFESLAANARIALHVRVLYGRDPHHITE 186
ABK78642      91 GHASVPLDESLSEAVVDLVKRPYHRIEmKIK----RPEVEG---IAKEDLEHFFDSLLRNLDCCIHLTVKYGNNDHHRVE 163
ALI34998      97 GNATVPMDESASSVAVDLIKRQYSHIDmKLE----REKIEN---MSQEDIIHFFQSFIGNINCCMHIIVHYGTNDHHKVE 169
CUR52680      93 GHASVPMDESLAEASLDLIKRQYQRIDlSII----RNQIEE---ISKEDLEHFFRSLAQNLNICMHVSVKYGENDHHKIE 165
WP_012800790  99 GQRLLPMDASLIMVAVDVCGRGYGITDlPFT----REMIGN---IATEMWKHFFYTFAINAQISLHIKVEYFDNNHHLIE 171
WP_075055341  98 GSAMVPMDEALAYVAIDLVKRQYHRMDvKLE----RASIEG---IPREDLEHFCRSLLQGLNACTHMVVEYGDNDHHKVE 170
WP_048106155  93 SFSSVPMDEALAETSLDLVKRQYHKITlSTK----RTKIEG---ISKEDLEHFFFSLAQNLNCCIHVTVKYGDNDHHKVE 165
WP_048188617  93 NYSSVPMDESLAESSVDLVRRPYGKINlSIK----RAQIEG---MSKEDIEHFFASLVQNLNSCIHINVRYGENDHHKIE 165
WP_086907056  93 SYASVPMDESLAEASIDLVKRPFSKLTlSIK----RSKIEN---VSKEDLEHFFQSLLQNLNSCIHLTVKYGDNDHHKVE 165
WP_103287792  95 GYAMVPMDDALAFVALDLVRRAYHAIDlKLA-----NGVED---MVKEDIEHFFTSFALNLNACIHVVVQYGSNDHHKVE 166
4GQU_A       187 AQYKAVARALRQAVEPDPrvSGVPSTKGAL 216
ABK78642     164 SAIKSLAVALRMAVSADPrrEGPPSTKGSM 193
ALI34998     170 SAIKAAAVALRNAIGIDPnsEGGPTTKGMM 199
CUR52680     166 AAIKAFAVAWRTAAGYDGkqKGIPSTKGAM 195
WP_012800790 172 ASFKGLAFALREALIAKE---GANSSKGSL 198
WP_075055341 171 AALKAFALALRAAASIDGrrKGVPSTKGAM 200
WP_048106155 166 AAIKSMAVAIRNAASNDPkqKGIPSTKGAM 195
WP_048188617 166 AAIKSLAVALRMAASVDKkqKGIPSTKGSM 195
WP_086907056 166 SAIKSLAVAFRSASSYDKkqKGIPSTKGSM 195
WP_103287792 167 AACKALGVALRNAAVINPr-KGIASTKGTI 195
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