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History Report on CCDS ID 6037  | Interpretation | Date | Source | Comment | Data |
|---|
| CCDS: Made public |
03/02/2005 |
NCBI |
|
CCDS Release: 1 |
| CCDS: Retained |
02/26/2007 |
NCBI |
|
CCDS Release: 3 |
| CCDS: Retained |
04/30/2008 |
NCBI |
|
CCDS Release: 5 |
| CCDS: Retained |
07/28/2009 |
NCBI |
|
CCDS Release: 6 |
| CCDS: Public note |
07/29/2010 |
NCBI |
This CCDS representation uses a downstream AUG start codon. This start codon has a strong Kozak signal and is restricted to human. An upstream start codon, which has a weak Kozak signal and is conserved in some other primates, is also present. The use of the upstream start codon would result in a protein that is 40 aa longer at the N-terminus. However, this would eliminate a signal peptide that is predicted for the shorter but not the longer N-terminus. PMID:9242611 shows experimental evidence for cleavage of a signal peptide following aa 25 from the downstream start, and this is also confirmed in PMID:15340161. Therefore, the downstream start codon is represented for this CCDS. |
CCDS version: 6037.1 |
| CCDS: Retained |
03/30/2011 |
NCBI |
|
CCDS Release: 8 |
| CCDS: Retained |
08/11/2011 |
NCBI |
|
CCDS Release: 9 |
| CCDS: Retained |
09/19/2012 |
NCBI |
|
CCDS Release: 11 |
| CCDS: Retained |
03/21/2013 |
NCBI |
|
CCDS Release: 12 |
| CCDS: Retained |
08/30/2013 |
NCBI |
|
CCDS Release: 14 |
| CCDS: Retained |
11/21/2013 |
NCBI |
|
CCDS Release: 15 |
| CCDS: Retained |
06/20/2014 |
NCBI |
|
CCDS Release: 17 |
| CCDS: Retained |
04/03/2015 |
NCBI |
|
CCDS Release: 18 |
| CCDS: Retained |
08/11/2016 |
NCBI |
|
CCDS Release: 20 |
| CCDS: Review status |
10/03/2016 |
NCBI |
|
by RefSeq, Havana and CCDS collaboration |
| CCDS: Retained |
05/16/2018 |
NCBI |
|
CCDS Release: 22 |
| CCDS: Retained |
08/10/2022 |
NCBI |
|
CCDS Release: 24 |
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