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Report for CCDS50756.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
50756.1 Public Mus musculus 2 Hck 23 108 98 CCDS HistoryNCBI Gene:15162Re-query CCDS DB by CCDS ID:50756.1Re-query CCDS DB by GeneID:15162See the combined annotation on chromosome 2 in Sequence Viewer

Public Note for CCDS 50756.1
This CCDS ID represents the shorter mouse Hck isoform, known as p56Hck, as described in PMID:1875927. This isoform initiates translation from a downstream AUG start codon. Alternative translation initiation from an upstream non-AUG (CUG) start codon, which is well-conserved and present in a strong Kozak signal context, produces an isoform that is 21 aa longer at the N-terminus. The longer isoform, which is known as p59Hck, is represented by CCDS 38284.1. These isoforms exhibit distinct subcellular localization, as indicated in PMID:1875927.

Public since: CCDS release 7, NCBI annotation release 37.2, Ensembl annotation release 61

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
CDS uses downstream AUG

Sequence IDs included in CCDS 50756.1

Original Current Source Nucleotide ID Protein ID Status in CCDS Seq. Status Links
Original member Current member EBI ENSMUST00000109799.7 ENSMUSP00000105423.1 Accepted alive Link to Ensembl Transcript Viewer:ENSMUST00000109799.7Link to Ensembl Protein Viewer:ENSMUSP00000105423.1Re-query CCDS DB by Nucleotide ID:ENSMUST00000109799Re-query CCDS DB by Protein ID:ENSMUSP00000105423
Original member Current member EBI ENSMUST00000189688.1 ENSMUSP00000141030.1 Accepted alive Link to Ensembl Transcript Viewer:ENSMUST00000189688.1Link to Ensembl Protein Viewer:ENSMUSP00000141030.1Re-query CCDS DB by Nucleotide ID:ENSMUST00000189688Re-query CCDS DB by Protein ID:ENSMUSP00000141030
Original member Current member NCBI NM_001172117.1 NP_001165588.1 Accepted alive Link to Nucleotide Sequence:NM_001172117.1Link to Protein Sequence:NP_001165588.1Re-query CCDS DB by Nucleotide ID:NM_001172117Re-query CCDS DB by Protein ID:NP_001165588Link to BLAST:NP_001165588.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001165588.1 503 P08103-2 503 100% 0 0

Chromosomal Locations for CCDS 50756.1

Assembly GRCm38.p6 (GCF_000001635.26)

On '+' strand of Chromosome 2 (NC_000068.7)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2See the combined annotation on chromosome 2 in Sequence Viewer

Chromosome Start Stop Links
2 153124171 153124287 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153128263 153128305 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153129043 153129142 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153129844 153129942 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153131221 153131324 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153134069 153134218 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153134624 153134776 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153136698 153136877 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153138262 153138338 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153144419 153144572 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153148947 153149078 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 153150947 153151149 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1512 nt):
ATGGGATGCGTGAAGTCCAGGTTCCTCCGAGATGGAAGCAAGGCCTCAAAAACAGAGCCAAGTGCCAATC
AGAAGGGCCCTGTGTATGTGCCGGATCCCACGTCCTCCAGCAAGCTGGGACCAAACAACAGCAACAGCAT
GCCCCCAGGGTTTGTGGAGGGCTCTGAGGATACCATTGTGGTCGCACTGTACGACTATGAGGCTATTCAC
CGTGAAGACCTCAGCTTCCAGAAGGGAGACCAGATGGTGGTTCTGGAGGAGGCTGGGGAGTGGTGGAAGG
CACGGTCCCTGGCTACCAAGAAGGAAGGCTACATCCCAAGCAACTATGTGGCTCGAGTTAACTCTTTGGA
GACAGAAGAGTGGTTCTTCAAGGGGATCAGCCGGAAGGATGCAGAGCGCCACCTCCTGGCTCCAGGCAAC
ATGCTGGGCTCCTTCATGATCCGGGACAGTGAGACCACCAAAGGGAGCTACTCGTTGTCTGTTCGAGACT
TTGACCCCCAGCACGGAGACACCGTGAAGCACTATAAGATCCGGACGCTGGACAGTGGAGGCTTCTACAT
CTCTCCAAGGAGCACCTTCAGCAGCCTGCAGGAACTCGTGCTCCACTACAAGAAGGGGAAGGATGGGCTC
TGCCAGAAGCTGTCAGTGCCCTGTGTGTCTCCCAAACCCCAGAAGCCATGGGAGAAAGATGCTTGGGAGA
TTCCTCGAGAATCCCTCCAGATGGAGAAGAAACTTGGAGCTGGGCAGTTTGGAGAAGTGTGGATGGCCAC
CTACAACAAGCACACCAAAGTGGCGGTGAAGACAATGAAGCCAGGGAGCATGTCCGTGGAGGCCTTCCTG
GCTGAGGCCAACCTGATGAAGTCGCTGCAGCATGACAAACTGGTGAAGCTACACGCTGTGGTCTCTCAGG
AGCCCATCTTTATTGTCACGGAGTTCATGGCCAAAGGAAGCCTGCTGGACTTTCTCAAGAGTGAAGAAGG
CAGCAAGCAGCCACTGCCAAAACTCATTGACTTCTCAGCCCAGATCTCAGAAGGCATGGCCTTCATTGAG
CAGAGGAACTACATCCACCGAGACCTGAGGGCTGCCAACATCTTAGTCTCTGCATCACTGGTGTGTAAGA
TTGCTGACTTTGGACTGGCACGAATCATCGAGGACAATGAGTACACAGCTCGGGAAGGAGCCAAGTTCCC
CATCAAGTGGACAGCTCCTGAAGCCATCAACTTTGGTTCCTTCACCATCAAGTCAGATGTCTGGTCCTTT
GGTATCCTGCTGATGGAAATTGTCACCTATGGCCGGATCCCTTACCCAGGTATGTCAAACCCAGAGGTGA
TTCGGGCACTAGAGCATGGGTACCGTATGCCTCGACCAGATAACTGTCCAGAAGAGCTCTACAATATCAT
GATCCGCTGCTGGAAGAACCGCCCCGAGGAACGGCCCACCTTTGAATACATCCAGAGTGTGCTGGATGAC
TTCTACACGGCCACTGAGAGCCAGTATCAGCAGCAGCCTTGA

Translation (503 aa):
MGCVKSRFLRDGSKASKTEPSANQKGPVYVPDPTSSSKLGPNNSNSMPPGFVEGSEDTIVVALYDYEAIH
REDLSFQKGDQMVVLEEAGEWWKARSLATKKEGYIPSNYVARVNSLETEEWFFKGISRKDAERHLLAPGN
MLGSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVLHYKKGKDGL
CQKLSVPCVSPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFL
AEANLMKSLQHDKLVKLHAVVSQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIE
QRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSF
GILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDD
FYTATESQYQQQP


Links Key
 Links to:   History report
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 Re-query CCDS DB by:   CCDS ID
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 Genome Browser Links:   Ensembl Genome Browser
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