NCBI CCDS banner
PubMed Entrez Gene BLAST OMIM
  

CCDS
Home
FTP
Process
Releases & Statistics

Collaborators
EBI
HGNC
MGI
NCBI

Contact Us
email CCDS

Genome Displays

Ensembl
NCBI
UCSC
VEGA

Related Resources
Gene
HomoloGene
MANE
RefSeq


Report for CCDS13471.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
13471.1 Public Homo sapiens 20 GNAS 24 110 108 CCDS HistoryNCBI Gene:2778Re-query CCDS DB by CCDS ID:13471.1Re-query CCDS DB by GeneID:2778See the combined annotation on chromosome 20 in Sequence Viewer

Public Note for CCDS 13471.1
This CCDS ID represents the protein described in PMIDs: 20443919 and 19412439. This transcript is supported by AF106697.1. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in in cow in PMIDs: 9111083 and 10729789. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
Nonsense-mediated decay (NMD) candidate

Sequence IDs included in CCDS 13471.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000313949.11 ENSP00000323571.7 Accepted alive Link to Ensembl Transcript Viewer:ENST00000313949.11Link to Ensembl Protein Viewer:ENSP00000323571.7Re-query CCDS DB by Nucleotide ID:ENST00000313949Re-query CCDS DB by Protein ID:ENSP00000323571
Original member Current member EBI ENST00000371075.7 ENSP00000360115.3 MANE Plus Clinical Accepted alive Link to Ensembl Transcript Viewer:ENST00000371075.7Link to Ensembl Protein Viewer:ENSP00000360115.3Re-query CCDS DB by Nucleotide ID:ENST00000371075Re-query CCDS DB by Protein ID:ENSP00000360115
Original member Current member EBI ENST00000371098.6 ENSP00000360139.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000371098.6Link to Ensembl Protein Viewer:ENSP00000360139.2Re-query CCDS DB by Nucleotide ID:ENST00000371098Re-query CCDS DB by Protein ID:ENSP00000360139
Original member Current member EBI ENST00000453292.7 ENSP00000392000.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000453292.7Link to Ensembl Protein Viewer:ENSP00000392000.2Re-query CCDS DB by Nucleotide ID:ENST00000453292Re-query CCDS DB by Protein ID:ENSP00000392000
Original member Current member EBI ENST00000419558.7 ENSP00000416234.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000419558.7Link to Ensembl Protein Viewer:ENSP00000416234.2Re-query CCDS DB by Nucleotide ID:ENST00000419558Re-query CCDS DB by Protein ID:ENSP00000416234
Original member Current member NCBI NM_016592.5 NP_057676.1 MANE Plus Clinical Accepted alive Link to Nucleotide Sequence:NM_016592.5Link to Protein Sequence:NP_057676.1Re-query CCDS DB by Nucleotide ID:NM_016592Re-query CCDS DB by Protein ID:NP_057676Link to BLAST:NP_057676.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_057676.1 245 O95467-1 245 100% 0 0

Chromosomal Locations for CCDS 13471.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 20 (NC_000020.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 20Link to Ensembl Genome Browser on chromosome 20See the combined annotation on chromosome 20 in Sequence Viewer

Chromosome Start Stop Links
20 58840107 58840844 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 20Link to Ensembl Genome Browser on chromosome 20

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (738 nt):
ATGGATCGGAGGTCCCGGGCTCAGCAGTGGCGCCGAGCTCGCCATAATTACAACGACCTGTGCCCGCCCA
TAGGCCGCCGGGCAGCCACCGCGCTCCTCTGGCTCTCCTGCTCCATCGCGCTCCTCCGCGCCCTTGCCAC
CTCCAACGCCCGTGCCCAGCAGCGCGCGGCTGCCCAACAGCGCCGGAGCTTCCTTAACGCCCACCACCGC
TCCGGCGCCCAGGTATTCCCTGAGTCCCCCGAATCGGAATCTGACCACGAGCACGAGGAGGCAGACCTTG
AGCTGTCCCTCCCCGAGTGCCTAGAGTACGAGGAAGAGTTCGACTACGAGACCGAGAGCGAGACCGAGTC
CGAAATCGAGTCCGAGACCGACTTCGAGACCGAGCCTGAGACCGCCCCCACCACTGAGCCCGAGACCGAG
CCTGAAGACGATCGCGGCCCGGTGGTGCCCAAGCACTCCACCTTCGGCCAGTCCCTCACCCAGCGTCTGC
ACGCTCTCAAGTTGCGAAGCCCCGACGCCTCCCCAAGTCGCGCGCCGCCCAGCACTCAGGAGCCCCAGAG
CCCCAGGGAAGGGGAGGAGCTCAAGCCCGAGGACAAAGATCCAAGGGACCCCGAAGAGTCGAAGGAGCCC
AAGGAGGAGAAGCAGCGGCGTCGCTGCAAGCCAAAGAAGCCCACCCGCCGTGACGCGTCCCCGGAGTCCC
CTTCCAAAAAGGGACCCATCCCCATCCGGCGTCACTAA

Translation (245 aa):
MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRAAAQQRRSFLNAHHR
SGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETE
PEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEP
KEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRRH


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

Disclaimer | Write to the Help Desk
NCBI | NLM | NIH