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Report for CCDS44300.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
44300.1 Public Homo sapiens 1 CDK18 24 110 108 CCDS HistoryNCBI Gene:5129Re-query CCDS DB by CCDS ID:44300.1Re-query CCDS DB by GeneID:5129See the combined annotation on chromosome 1 in Sequence Viewer

Public Note for CCDS 44300.1
This CCDS representation uses the 5'-most in-frame start codon found in the transcript. It should be noted that this start codon has a weak Kozak signal, and its conservation is restricted to primate species, squirrel, rock hyrax and armadillo. Two better conserved potential start codons with stronger Kozak signals are located two and five codons downstream, respectively. It is possible that leaky scanning by ribosomes would allow one of the downstream start codons to be used some of the time. There is no experimental evidence indicating which start codon is preferentially used in vivo.

Public since: CCDS release 6, NCBI annotation release 37.1, Ensembl annotation release 55

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 44300.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000360066.6 ENSP00000353176.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000360066.6Link to Ensembl Protein Viewer:ENSP00000353176.2Re-query CCDS DB by Nucleotide ID:ENST00000360066Re-query CCDS DB by Protein ID:ENSP00000353176
Original member Current member EBI ENST00000429964.7 ENSP00000399082.2 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000429964.7Link to Ensembl Protein Viewer:ENSP00000399082.2Re-query CCDS DB by Nucleotide ID:ENST00000429964Re-query CCDS DB by Protein ID:ENSP00000399082
Original member Current member NCBI NM_002596.4 NP_002587.2 Accepted alive Link to Nucleotide Sequence:NM_002596.4Link to Protein Sequence:NP_002587.2Re-query CCDS DB by Nucleotide ID:NM_002596Re-query CCDS DB by Protein ID:NP_002587Link to BLAST:NP_002587.2
Original member Current member NCBI NM_212502.3 NP_997667.1 MANE Select Accepted alive Link to Nucleotide Sequence:NM_212502.3Link to Protein Sequence:NP_997667.1Re-query CCDS DB by Nucleotide ID:NM_212502Re-query CCDS DB by Protein ID:NP_997667Link to BLAST:NP_997667.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_002587.2 474 Q07002-2 474 100% 0 0
NP_997667.1 474 Q07002-2 474 100% 0 0

Chromosomal Locations for CCDS 44300.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 1 (NC_000001.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1See the combined annotation on chromosome 1 in Sequence Viewer

Chromosome Start Stop Links
1 205523168 205523297 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205523483 205523625 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205524232 205524357 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205525139 205525195 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205526065 205526179 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205526367 205526461 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205526775 205526837 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205527794 205527917 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205528048 205528168 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205528999 205529096 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205529324 205529429 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205529521 205529563 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205530259 205530349 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205530628 205530705 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1
1 205531344 205531378 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 1Link to Ensembl Genome Browser on chromosome 1

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1425 nt):
ATGATCATGAACAAGATGAAGAACTTTAAGCGCCGTTTCTCCCTGTCAGTGCCCCGCACTGAGACCATTG
AAGAATCCTTGGCTGAATTCACGGAGCAATTCAACCAGCTCCACAACCGGCGGAATGAGAACTTGCAGCT
CGGTCCTCTTGGCAGAGACCCCCCGCAGGAGTGCAGCACCTTCTCCCCAACAGACAGCGGGGAGGAGCCG
GGGCAGCTCTCCCCTGGCGTGCAGTTCCAGCGGCGGCAGAACCAGCGCCGCTTCTCCATGGAGGACGTCA
GCAAGAGGCTCTCTCTGCCCATGGATATCCGCCTGCCCCAGGAATTCCTACAGAAGCTACAGATGGAGAG
CCCAGATCTGCCCAAGCCGCTCAGCCGCATGTCCCGCCGGGCCTCCCTGTCAGACATTGGCTTTGGGAAA
CTGGAAACATACGTGAAACTGGACAAACTGGGAGAGGGCACCTATGCCACAGTCTTCAAAGGGCGCAGCA
AACTGACGGAGAACCTTGTGGCCCTGAAAGAGATCCGGCTGGAGCACGAGGAGGGAGCGCCCTGCACTGC
CATCCGAGAGGTGTCTCTGCTGAAGAACCTGAAGCACGCCAATATTGTGACCCTGCATGACCTCATCCAC
ACAGATCGGTCCCTCACCCTGGTGTTTGAGTACCTGGACAGTGACCTGAAGCAGTATCTGGACCACTGTG
GGAACCTCATGAGCATGCACAACGTCAAGATTTTCATGTTCCAGCTGCTCCGGGGCCTCGCCTACTGTCA
CCACCGCAAGATCCTGCACCGGGACCTGAAGCCCCAGAACCTGCTCATCAACGAGAGGGGGGAGCTGAAG
CTGGCCGACTTTGGACTGGCCAGGGCCAAGTCAGTGCCCACAAAGACTTACTCCAATGAGGTGGTGACCC
TGTGGTACAGGCCCCCCGATGTGCTGCTGGGATCCACAGAGTACTCCACCCCCATTGATATGTGGGGCGT
GGGCTGCATCCACTACGAGATGGCCACAGGGAGGCCCCTCTTCCCGGGCTCCACAGTCAAGGAGGAGCTG
CACCTCATCTTTCGCCTCCTCGGGACCCCCACAGAAGAGACGTGGCCCGGCGTGACCGCCTTCTCTGAGT
TCCGCACCTACAGCTTCCCCTGCTACCTCCCGCAGCCGCTCATCAACCACGCGCCCAGGTTGGATACGGA
TGGCATCCACCTCCTGAGCAGCCTGCTCCTGTATGAATCCAAGAGTCGCATGTCAGCAGAGGCTGCCCTG
AGTCACTCCTACTTCCGGTCTCTGGGAGAGCGTGTGCACCAGCTTGAAGACACTGCCTCCATCTTCTCCC
TGAAGGAGATCCAGCTCCAGAAGGACCCAGGCTACCGAGGCTTGGCCTTCCAGCAGCCAGGACGAGGGAA
GAACAGGCGGCAGAGCATCTTCTGA

Translation (474 aa):
MIMNKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPPQECSTFSPTDSGEEP
GQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLSRMSRRASLSDIGFGK
LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIH
TDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELK
LADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEEL
HLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAAL
SHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF


Links Key
 Links to:   History report
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  Nucleotide report
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 Re-query CCDS DB by:   CCDS ID
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 Genome Browser Links:   Ensembl Genome Browser
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