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Report for CCDS31258.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
31258.2 Public Homo sapiens 10 TCTN3 24 110 108 CCDS HistoryNCBI Gene:26123Re-query CCDS DB by CCDS ID:31258.2Re-query CCDS DB by GeneID:26123See the combined annotation on chromosome 10 in Sequence Viewer

Public Note for CCDS 31258.1
The coding region has been updated to represent an alternative splice pattern that is more supported by the available transcript and protein data. The update results in an extended protein N-terminus and in the presence of an additional internal segment. A downstream AUG translation start codon is selected for the update based on better conservation support, and on a higher probability of an N-terminal signal peptide being present in the resulting protein. Data in PMID:16357211 suggest that the protein is secreted. The use of an alternative upstream AUG start codon would result in a protein that is 18 aa longer at the N-terminus. Translation from the annotated downstream start codon is likely to occur via leaky scanning.

Public since: CCDS release 3, NCBI annotation release 36.2, Ensembl annotation release 41

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 31258.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000371217.10 ENSP00000360261.5 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000371217.10Link to Ensembl Protein Viewer:ENSP00000360261.5Re-query CCDS DB by Nucleotide ID:ENST00000371217Re-query CCDS DB by Protein ID:ENSP00000360261
Original member Current member NCBI NM_015631.6 NP_056446.4 MANE Select Accepted alive Link to Nucleotide Sequence:NM_015631.6Link to Protein Sequence:NP_056446.4Re-query CCDS DB by Nucleotide ID:NM_015631Re-query CCDS DB by Protein ID:NP_056446Link to BLAST:NP_056446.4

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_056446.4 607 Q6NUS6-1 607 100% 0 0

Chromosomal Locations for CCDS 31258.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 10 (NC_000010.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10See the combined annotation on chromosome 10 in Sequence Viewer

Chromosome Start Stop Links
10 95664067 95664300 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95680472 95680609 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95682651 95682804 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95683101 95683195 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95683522 95683629 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95684499 95684624 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95685556 95685636 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95686495 95686530 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95687044 95687159 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95687247 95687355 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95687592 95687719 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95692920 95693038 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95693353 95693476 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10
10 95693644 95693899 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 10Link to Ensembl Genome Browser on chromosome 10

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1824 nt):
ATGCGCACCCCACAGCTCGCGCTCCTGCAAGTGTTCTTTCTGGTGTTCCCCGATGGCGTCCGGCCTCAGC
CCTCTTCCTCCCCATCAGGGGCAGTGCCCACGTCTTTGGAGCTGCAGCGAGGGACGGATGGCGGAACCCT
CCAGTCCCCTTCAGAGGCGACTGCAACTCGCCCGGCCGTGCCTGGACTCCCTACAGTGGTCCCTACTCTC
GTGACTCCCTCGGCCCCTGGGAATAGGACTGTGGACCTCTTCCCAGTCTTACCGATCTGTGTCTGTGACT
TGACTCCTGGAGCCTGCGATATAAATTGCTGCTGCGACAGGGACTGCTATCTTCTCCATCCGAGGACAGT
TTTCTCCTTCTGCCTTCCAGGCAGCGTAAGGTCTTCAAGCTGGGTTTGTGTAGACAACTCTGTTATCTTC
AGGAGTAATTCCCCGTTTCCTTCAAGAGTTTTCATGGATTCTAATGGAATCAGGCAGTTTTGTGTCCATG
TGAACAACTCAAACTTAAACTATTTCCAGAAGCTTCAAAAGGTCAATGCAACCAACTTCCAGGCCCTGGC
TGCAGAGTTTGGAGGCGAATCATTCACTTCAACATTCCAAACTCAATCACCACCATCTTTTTACAGGGCT
GGGGACCCCATTCTTACTTACTTCCCCAAGTGGTCTGTAATAAGCTTGCTGAGACAACCTGCAGGAGTTG
GAGCTGGGGGACTCTGTGCTGAAAGCAATCCTGCAGGTTTCCTAGAGAGTAAAAGTACAACTTGCACTCG
TTTTTTCAAGAACCTGGCTAGTAGCTGTACCTTGGATTCAGCCCTCAATGCTGCCTCTTACTATAACTTC
ACAGTCTTAAAGGTTCCAAGAAGCATGACTGATCCACAGAATATGGAGTTCCAGGTTCCTGTAATACTTA
CCTCACAGGCTAATGCTCCTCTGTTGGCTGGAAACACTTGTCAGAATGTAGTTTCTCAGGTCACCTATGA
GATAGAGACCAATGGGACTTTTGGAATCCAGAAAGTTTCTGTCAGTTTGGGACAAACCAACCTGACTGTT
GAGCCAGGCGCTTCCTTACAGCAACACTTCATCCTTCGCTTCAGGGCTTTTCAACAGAGCACAGCTGCTT
CTCTCACCAGTCCTAGAAGTGGGAATCCTGGCTATATAGTTGGGAAGCCACTCTTGGCTCTGACTGATGA
TATAAGTTACTCAATGACCCTCTTACAGAGCCAGGGTAATGGAAGTTGCTCTGTTAAAAGACATGAAGTG
CAGTTTGGAGTGAATGCAATATCTGGATGCAAGCTCAGGTTGAAGAAGGCAGACTGCAGCCACTTGCAGC
AGGAGATTTATCAGACTCTTCATGGAAGGCCCAGACCAGAGTATGTTGCCATCTTTGGTAATGCTGACCC
AGCCCAGAAAGGAGGGTGGACCAGGATCCTCAACAGGCACTGCAGCATTTCAGCTATAAACTGTACTTCC
TGCTGTCTCATACCAGTTTCCCTGGAGATCCAGGTATTGTGGGCATATGTAGGTCTCCTGTCCAACCCGC
AAGCTCATGTATCAGGAGTTCGATTCCTATACCAGTGCCAGTCTATACAGGATTCTCAGCAAGTTACAGA
AGTATCTTTGACAACTCTTGTGAACTTTGTGGACATTACCCAGAAGCCACAGCCTCCAAGGGGCCAACCC
AAAATGGACTGGAAATGGCCATTCGACTTCTTTCCCTTCAAAGTGGCATTCAGCAGAGGAGTATTCTCTC
AAAAATGCTCAGTCTCTCCCATCCTTATCCTGTGCCTCTTACTACTTGGAGTTCTCAACCTAGAGACTAT
GTGA

Translation (607 aa):
MRTPQLALLQVFFLVFPDGVRPQPSSSPSGAVPTSLELQRGTDGGTLQSPSEATATRPAVPGLPTVVPTL
VTPSAPGNRTVDLFPVLPICVCDLTPGACDINCCCDRDCYLLHPRTVFSFCLPGSVRSSSWVCVDNSVIF
RSNSPFPSRVFMDSNGIRQFCVHVNNSNLNYFQKLQKVNATNFQALAAEFGGESFTSTFQTQSPPSFYRA
GDPILTYFPKWSVISLLRQPAGVGAGGLCAESNPAGFLESKSTTCTRFFKNLASSCTLDSALNAASYYNF
TVLKVPRSMTDPQNMEFQVPVILTSQANAPLLAGNTCQNVVSQVTYEIETNGTFGIQKVSVSLGQTNLTV
EPGASLQQHFILRFRAFQQSTAASLTSPRSGNPGYIVGKPLLALTDDISYSMTLLQSQGNGSCSVKRHEV
QFGVNAISGCKLRLKKADCSHLQQEIYQTLHGRPRPEYVAIFGNADPAQKGGWTRILNRHCSISAINCTS
CCLIPVSLEIQVLWAYVGLLSNPQAHVSGVRFLYQCQSIQDSQQVTEVSLTTLVNFVDITQKPQPPRGQP
KMDWKWPFDFFPFKVAFSRGVFSQKCSVSPILILCLLLLGVLNLETM


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
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 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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