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Report for CCDS2342.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
2342.1 Public Homo sapiens 2 CASP8 24 110 108 CCDS HistoryNCBI Gene:841Re-query CCDS DB by CCDS ID:2342.1Re-query CCDS DB by GeneID:841See the combined annotation on chromosome 2 in Sequence Viewer

Public Note for CCDS 2342.1
This CCDS representation is based on AF422928.1 and U58143.1, and on data in PMID:11917123. This 479 aa isoform is also supported by homologous proteins, including pig NP_001026949.1, cow NP_001039435.1, mouse NP_033942.1, rat NP_071613.1 and chicken NP_989923.1. In addition, macaque AB172864.1 supports the full-length splice pattern.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 2342.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000440732.6 ENSP00000396869.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000440732.6Link to Ensembl Protein Viewer:ENSP00000396869.2Re-query CCDS DB by Nucleotide ID:ENST00000440732Re-query CCDS DB by Protein ID:ENSP00000396869
Original member Current member EBI ENST00000413726.6 ENSP00000397528.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000413726.6Link to Ensembl Protein Viewer:ENSP00000397528.2Re-query CCDS DB by Nucleotide ID:ENST00000413726Re-query CCDS DB by Protein ID:ENSP00000397528
Original member Current member EBI ENST00000432109.6 ENSP00000412523.2 Accepted alive Link to Ensembl Transcript Viewer:ENST00000432109.6Link to Ensembl Protein Viewer:ENSP00000412523.2Re-query CCDS DB by Nucleotide ID:ENST00000432109Re-query CCDS DB by Protein ID:ENSP00000412523
Original member Current member EBI ENST00000673742.1 ENSP00000501268.1 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000673742.1Link to Ensembl Protein Viewer:ENSP00000501268.1Re-query CCDS DB by Nucleotide ID:ENST00000673742Re-query CCDS DB by Protein ID:ENSP00000501268
Original member Current member EBI ENST00000696067.1 ENSP00000512369.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000696067.1Link to Ensembl Protein Viewer:ENSP00000512369.1Re-query CCDS DB by Nucleotide ID:ENST00000696067Re-query CCDS DB by Protein ID:ENSP00000512369
Original member Current member NCBI NM_001372051.1 NP_001358980.1 MANE Select Accepted alive Link to Nucleotide Sequence:NM_001372051.1Link to Protein Sequence:NP_001358980.1Re-query CCDS DB by Nucleotide ID:NM_001372051Re-query CCDS DB by Protein ID:NP_001358980Link to BLAST:NP_001358980.1
Original member Current member NCBI NM_001400648.1 NP_001387577.1 Accepted alive Link to Nucleotide Sequence:NM_001400648.1Link to Protein Sequence:NP_001387577.1Re-query CCDS DB by Nucleotide ID:NM_001400648Re-query CCDS DB by Protein ID:NP_001387577Link to BLAST:NP_001387577.1
Original member Current member NCBI NM_001400651.1 NP_001387580.1 Accepted alive Link to Nucleotide Sequence:NM_001400651.1Link to Protein Sequence:NP_001387580.1Re-query CCDS DB by Nucleotide ID:NM_001400651Re-query CCDS DB by Protein ID:NP_001387580Link to BLAST:NP_001387580.1
Original member Current member NCBI NM_001400653.1 NP_001387582.1 Accepted alive Link to Nucleotide Sequence:NM_001400653.1Link to Protein Sequence:NP_001387582.1Re-query CCDS DB by Nucleotide ID:NM_001400653Re-query CCDS DB by Protein ID:NP_001387582Link to BLAST:NP_001387582.1
Original member Current member NCBI NM_001400654.1 NP_001387583.1 Accepted alive Link to Nucleotide Sequence:NM_001400654.1Link to Protein Sequence:NP_001387583.1Re-query CCDS DB by Nucleotide ID:NM_001400654Re-query CCDS DB by Protein ID:NP_001387583Link to BLAST:NP_001387583.1
Original member Current member NCBI NM_001400655.1 NP_001387584.1 Accepted alive Link to Nucleotide Sequence:NM_001400655.1Link to Protein Sequence:NP_001387584.1Re-query CCDS DB by Nucleotide ID:NM_001400655Re-query CCDS DB by Protein ID:NP_001387584Link to BLAST:NP_001387584.1
Original member Current member NCBI NM_001400656.1 NP_001387585.1 Accepted alive Link to Nucleotide Sequence:NM_001400656.1Link to Protein Sequence:NP_001387585.1Re-query CCDS DB by Nucleotide ID:NM_001400656Re-query CCDS DB by Protein ID:NP_001387585Link to BLAST:NP_001387585.1
Original member Current member NCBI NM_001400657.1 NP_001387586.1 Accepted alive Link to Nucleotide Sequence:NM_001400657.1Link to Protein Sequence:NP_001387586.1Re-query CCDS DB by Nucleotide ID:NM_001400657Re-query CCDS DB by Protein ID:NP_001387586Link to BLAST:NP_001387586.1
Original member NCBI NM_033355.3 NP_203519.1 Updated not alive Link to Nucleotide Sequence:NM_033355.3Link to Protein Sequence:NP_203519.1Re-query CCDS DB by Nucleotide ID:NM_033355Re-query CCDS DB by Protein ID:NP_203519
Current member NCBI NM_033355.4 NP_203519.1 Accepted alive Link to Nucleotide Sequence:NM_033355.4Link to Protein Sequence:NP_203519.1Re-query CCDS DB by Nucleotide ID:NM_033355Re-query CCDS DB by Protein ID:NP_203519Link to BLAST:NP_203519.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001358980.1 479 Q14790-1 479 100% 0 0
NP_001387577.1 479 Q14790-1 479 100% 0 0
NP_001387580.1 479 Q14790-1 479 100% 0 0
NP_001387582.1 479 Q14790-1 479 100% 0 0
NP_001387583.1 479 Q14790-1 479 100% 0 0
NP_001387584.1 479 Q14790-1 479 100% 0 0
NP_001387585.1 479 Q14790-1 479 100% 0 0
NP_001387586.1 479 Q14790-1 479 100% 0 0
NP_203519.1 479 Q14790-1 479 100% 0 0

Chromosomal Locations for CCDS 2342.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 2 (NC_000002.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2See the combined annotation on chromosome 2 in Sequence Viewer

Chromosome Start Stop Links
2 201266487 201266791 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201271516 201271621 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201272638 201272776 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201272898 201272942 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201274889 201274953 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201276827 201276968 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201284816 201285317 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2
2 201286459 201286594 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 2Link to Ensembl Genome Browser on chromosome 2

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1440 nt):
ATGGACTTCAGCAGAAATCTTTATGATATTGGGGAACAACTGGACAGTGAAGATCTGGCCTCCCTCAAGT
TCCTGAGCCTGGACTACATTCCGCAAAGGAAGCAAGAACCCATCAAGGATGCCTTGATGTTATTCCAGAG
ACTCCAGGAAAAGAGAATGTTGGAGGAAAGCAATCTGTCCTTCCTGAAGGAGCTGCTCTTCCGAATTAAT
AGACTGGATTTGCTGATTACCTACCTAAACACTAGAAAGGAGGAGATGGAAAGGGAACTTCAGACACCAG
GCAGGGCTCAAATTTCTGCCTACAGGGTCATGCTCTATCAGATTTCAGAAGAAGTGAGCAGATCAGAATT
GAGGTCTTTTAAGTTTCTTTTGCAAGAGGAAATCTCCAAATGCAAACTGGATGATGACATGAACCTGCTG
GATATTTTCATAGAGATGGAGAAGAGGGTCATCCTGGGAGAAGGAAAGTTGGACATCCTGAAAAGAGTCT
GTGCCCAAATCAACAAGAGCCTGCTGAAGATAATCAACGACTATGAAGAATTCAGCAAAGAGAGAAGCAG
CAGCCTTGAAGGAAGTCCTGATGAATTTTCAAATGGGGAGGAGTTGTGTGGGGTAATGACAATCTCGGAC
TCTCCAAGAGAACAGGATAGTGAATCACAGACTTTGGACAAAGTTTACCAAATGAAAAGCAAACCTCGGG
GATACTGTCTGATCATCAACAATCACAATTTTGCAAAAGCACGGGAGAAAGTGCCCAAACTTCACAGCAT
TAGGGACAGGAATGGAACACACTTGGATGCAGGGGCTTTGACCACGACCTTTGAAGAGCTTCATTTTGAG
ATCAAGCCCCACGATGACTGCACAGTAGAGCAAATCTATGAGATTTTGAAAATCTACCAACTCATGGACC
ACAGTAACATGGACTGCTTCATCTGCTGTATCCTCTCCCATGGAGACAAGGGCATCATCTATGGCACTGA
TGGACAGGAGGCCCCCATCTATGAGCTGACATCTCAGTTCACTGGTTTGAAGTGCCCTTCCCTTGCTGGA
AAACCCAAAGTGTTTTTTATTCAGGCTTGTCAGGGGGATAACTACCAGAAAGGTATACCTGTTGAGACTG
ATTCAGAGGAGCAACCCTATTTAGAAATGGATTTATCATCACCTCAAACGAGATATATCCCGGATGAGGC
TGACTTTCTGCTGGGGATGGCCACTGTGAATAACTGTGTTTCCTACCGAAACCCTGCAGAGGGAACCTGG
TACATCCAGTCACTTTGCCAGAGCCTGAGAGAGCGATGTCCTCGAGGCGATGATATTCTCACCATCCTGA
CTGAAGTGAACTATGAAGTAAGCAACAAGGATGACAAGAAAAACATGGGGAAACAGATGCCTCAGCCTAC
TTTCACACTAAGAAAAAAACTTGTCTTCCCTTCTGATTGA

Translation (479 aa):
MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRIN
RLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLL
DIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE
IKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAG
KPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTW
YIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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