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Report for CCDS3579.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
3579.2 Public Homo sapiens 4 SHROOM3 24 110 108 CCDS HistoryNCBI Gene:57619Re-query CCDS DB by CCDS ID:3579.2Re-query CCDS DB by GeneID:57619See the combined annotation on chromosome 4 in Sequence Viewer

Public Note for CCDS 3579.1
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript data. Two possible start codons are present in this update, with the downstream AUG codon have a stronger Kozak signal. The upstream AUG codon, as represented in this update, is conserved in several mammalian species, but not in mouse or dog, whereas the downstream AUG is more widely conserved. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 1 aa shorter at the N-terminus.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 3579.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000296043.7 ENSP00000296043.6 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000296043.7Link to Ensembl Protein Viewer:ENSP00000296043.6Re-query CCDS DB by Nucleotide ID:ENST00000296043Re-query CCDS DB by Protein ID:ENSP00000296043
Original member Current member NCBI NM_020859.4 NP_065910.3 MANE Select Accepted alive Link to Nucleotide Sequence:NM_020859.4Link to Protein Sequence:NP_065910.3Re-query CCDS DB by Nucleotide ID:NM_020859Re-query CCDS DB by Protein ID:NP_065910Link to BLAST:NP_065910.3

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_065910.3 1996 Q8TF72-1 1996 100% 0 0

Chromosomal Locations for CCDS 3579.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 4 (NC_000004.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4See the combined annotation on chromosome 4 in Sequence Viewer

Chromosome Start Stop Links
4 76436053 76436220 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76555609 76555763 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76710156 76710287 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76730804 76730935 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76738761 76741926 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76749017 76749090 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76754311 76755192 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76756449 76756937 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76759545 76759695 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76770626 76770898 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 76778809 76779177 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (5991 nt):
ATGATGAGGACCACTGAAGACTTCCACAAGCCTAGTGCCACATTAAACTCTAACACGGCCACCAAGGGAA
GGTACATTTATCTGGAGGCATTCCTGGAGGGAGGAGCTCCCTGGGGTTTTACTCTAAAGGGTGGCCTGGA
GCACGGAGAACCATTAATCATCTCTAAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCCAAACTG
CAGGCTGGGGATGAGGTTGTGCACATCAATGAGGTGACTCTGAGCAGCTCCAGAAAGGAGGCAGTTTCCC
TGGTGAAAGGATCCTACAAGACCCTCAGGCTGGTAGTGCGCAGAGATGTGTGCACAGACCCAGGCCATGC
AGATACTGGTGCCTCTAACTTCGTCAGCCCAGAACACCTCACCTCTGGCCCCCAGCACAGGAAAGCAGCG
TGGTCAGGAGGGGTTAAACTTCGGCTGAAGCACAGGCGCAGTGAGCCTGCAGGCCGACCTCACTCGTGGC
ACACAACTAAATCTGGGGAGAAGCAACCCGATGCCAGCATGATGCAGATATCTCAGGGTATGATCGGCCC
TCCTTGGCACCAAAGCTACCATTCCAGCTCCTCTACTAGTGACCTCTCCAACTATGACCATGCTTATCTA
AGGCGGAGCCCTGACCAGTGCAGCTCCCAGGGGAGCATGGAGAGCCTGGAGCCCAGTGGGGCATACCCAC
CCTGTCATCTTTCCCCTGCCAAGTCCACCGGCAGCATTGACCAGCTCAGCCACTTCCATAACAAGAGAGA
CTCGGCTTACAGCTCTTTCTCCACCAGTTCTAGCATCCTAGAGTATCCACACCCTGGCATCTCTGGCCGG
GAGCGTTCAGGCTCCATGGACAATACTTCTGCTCGAGGTGGCCTCCTCGAAGGGATGAGGCAGGCAGATA
TTCGCTATGTCAAGACAGTCTATGACACCCGGAGGGGAGTCTCAGCAGAGTATGAGGTGAACTCTTCAGC
CCTGCTGCTTCAAGGTAGGGAGGCCCGAGCCTCAGCAAATGGTCAGGGCTATGATAAATGGTCTAATATT
CCTCGGGGCAAGGGAGTGCCACCCCCATCCTGGAGCCAGCAGTGCCCCAGTTCCTTGGAGACTGCCACGG
ACAACCTTCCTCCTAAGGTGGGTGCACCCCTGCCTCCAGCTCGGAGTGACAGTTACGCAGCATTTCGGCA
CCGTGAGCGGCCCAGCTCCTGGTCTAGCCTTGATCAGAAACGGCTCTGCCGGCCTCAGGCAAACTCTTTA
GGCTCCCTGAAGTCTCCATTCATAGAGGAGCAGCTGCATACTGTGCTGGAGAAGAGTCCAGAGAACAGCC
CCCCAGTGAAGCCCAAGCATAACTATACCCAGAAGGCCCAACCTGGCCAACCTCTGCTGCCGACCAGCAT
CTACCCGGTACCTTCCCTGGAGCCACACTTTGCCCAGGTGCCTCAGCCTTCTGTGAGTAGCAACGGTATG
CTCTACCCTGCACTGGCCAAGGAGAGTGGATACATAGCCCCTCAGGGAGCATGCAACAAGATGGCTACCA
TTGATGAGAATGGGAACCAGAATGGATCTGGCAGGCCTGGGTTTGCCTTCTGCCAGCCCTTAGAACATGA
CTTGCTGTCCCCAGTGGAGAAGAAACCAGAAGCTACAGCCAAGTATGTCCCCTCCAAAGTCCATTTCTGT
TCAGTGCCTGAAAATGAGGAGGATGCCTCCCTGAAGAGACATCTCACACCTCCCCAAGGCAACAGCCCAC
ATTCCAATGAGAGAAAGAGCACCCACAGTAACAAACCATCTTCTCATCCCCACAGCCTCAAATGCCCTCA
GGCTCAGGCCTGGCAAGCGGGTGAAGACAAGAGATCTTCCAGGCTCTCAGAGCCCTGGGAGGGCGATTTC
CAGGAAGACCACAATGCCAACCTCTGGAGGAGGCTGGAGAGAGAAGGCCTAGGCCAGAGCCTGTCAGGCA
ACTTTGGCAAGACCAAGTCAGCCTTCTCATCTCTCCAGAACATTCCTGAGAGTCTGAGAAGACACAGCAG
CCTGGAGCTAGGCCGGGGAACCCAGGAGGGTTACCCCGGGGGCAGGCCCACCTGTGCAGTCAACACCAAG
GCAGAAGACCCTGGGAGGAAAGCCGCTCCTGACCTCGGGAGCCATCTGGACCGGCAGGTTTCCTACCCGC
GGCCCGAGGGGAGGACCGGTGCCTCGGCTTCTTTCAACAGCACAGACCCAAGTCCCGAAGAGCCGCCTGC
CCCCTCGCACCCGCACACATCCAGTCTGGGCCGGAGGGGGCCCGGCCCAGGCAGCGCCTCGGCTCTTCAG
GGCTTTCAGTACGGGAAGCCCCACTGCTCGGTGCTGGAGAAGGTCTCCAAATTCGAGCAGCGAGAGCAAG
GGAGCCAGAGACCGAGTGTGGGCGGCTCTGGTTTTGGCCATAACTATAGGCCCCACAGGACCGTCTCAAC
TTCCAGTACTTCTGGGAATGACTTCGAGGAGACAAAAGCACACATTCGTTTCTCTGAGTCAGCTGAACCC
CTAGGCAACGGGGAGCAGCACTTCAAAAACGGGGAGCTGAAGTTGGAAGAGGCTTCCCGGCAGCCCTGCG
GTCAGCAGCTGAGCGGAGGAGCGTCGGACAGCGGCCGTGGCCCCCAGAGGCCGGACGCTCGGCTCCTCCG
TAGCCAGAGCACCTTCCAGCTCTCCAGCGAGCCAGAGAGGGAGCCCGAGTGGCGGGACAGGCCCGGCTCG
CCCGAATCGCCCCTGCTGGATGCCCCCTTCAGCCGCGCCTACCGGAACAGCATCAAGGACGCACAGTCCC
GTGTCTTGGGGGCCACCTCCTTTCGACGTCGAGACCTGGAGCTGGGGGCGCCCGTGGCGTCGAGGTCCTG
GCGGCCACGGCCTTCCTCGGCCCACGTGGGGCTGCGGAGCCCCGAGGCGTCGGCCTCCGCCTCCCCGCAC
ACGCCCCGGGAGCGGCACAGCGTGACCCCTGCTGAGGGCGACCTGGCCAGGCCCGTGCCCCCTGCCGCCC
GGAGAGGTGCTCGCCGGCGCCTGACTCCCGAGCAGAAGAAGCGCTCCTACTCGGAGCCCGAGAAGATGAA
CGAGGTGGGGATCGTGGAGGAGGCCGAACCGGCACCCCTGGGCCCGCAGAGAAATGGGATGCGTTTCCCG
GAGAGCAGCGTGGCCGACCGGCGCCGTCTCTTCGAGCGCGATGGCAAGGCCTGCTCCACGCTCAGCCTGT
CGGGGCCCGAGCTGAAGCAGTTCCAGCAGAGCGCCCTGGCGGACTACATCCAGCGCAAGACCGGCAAGCG
GCCTACCTCCGCCGCCGGCTGCAGCCTCCAGGAGCCCGGGCCACTGCGTGAGCGCGCCCAGAGTGCCTAC
CTCCAGCCCGGCCCCGCGGCGCTCGAAGGCTCCGGCCTCGCCTCGGCCTCCAGCTTGAGCTCACTGCGGG
AGCCCAGCCTGCAGCCCCGCAGGGAGGCCACGCTCCTGCCGGCCACAGTTGCAGAAACCCAGCAGGCTCC
CCGAGATCGCAGCAGCTCCTTCGCCGGTGGCCGCCGCCTCGGGGAACGGCGACGCGGGGACCTGCTTAGC
GGAGCAAACGGTGGAACAAGGGGCACCCAGAGAGGGGATGAGACCCCCAGGGAGCCATCCTCCTGGGGGG
CCAGGGCCGGGAAGTCCATGTCGGCCGAGGACCTGCTGGAACGCTCGGACGTCCTTGCGGGCCCTGTCCA
TGTGAGGTCCAGGTCATCTCCCGCCACCGCAGACAAGCGCCAGGATGTGCTTTTGGGGCAAGACAGTGGC
TTTGGTCTTGTGAAGGATCCATGTTATTTGGCTGGTCCTGGATCTAGGTCACTCAGTTGTTCAGAAAGAG
GCCAAGAAGAGATGCTGCCGCTCTTCCACCATCTCACCCCTCGTTGGGGTGGTTCAGGCTGCAAAGCCAT
TGGTGATTCCTCCGTTCCTAGTGAATGTCCTGGAACCCTGGACCATCAGAGGCAAGCCAGTAGGACACCC
TGCCCCAGGCCACCACTGGCAGGAACGCAAGGGCTGGTCACAGACACCAGGGCTGCACCCCTGACCCCAA
TTGGCACCCCTCTGCCTTCAGCCATTCCCTCTGGCTACTGCTCACAGGACGGTCAGACAGGGCGACAGCC
TCTCCCGCCCTACACCCCTGCCATGATGCACAGAAGCAATGGTCACACCCTGACCCAGCCTCCCGGTCCA
AGAGGCTGTGAGGGCGATGGCCCAGAGCATGGGGTAGAAGAGGGAACGAGGAAGAGGGTCTCGCTGCCTC
AGTGGCCACCTCCTTCTCGAGCAAAGTGGGCCCACGCAGCCAGAGAGGACAGCCTTCCTGAGGAATCCTC
AGCCCCTGATTTTGCAAACCTGAAGCACTATCAAAAACAGCAGAGTCTTCCAAGTTTATGCAGCACTTCT
GACCCAGACACACCTCTTGGGGCCCCGAGCACTCCAGGGAGGATCTCCCTCCGAATATCTGAGTCTGTCC
TGCGGGACTCCCCGCCACCTCATGAGGATTATGAAGACGAAGTGTTTGTGAGGGATCCGCACCCCAAGGC
CACGTCCAGCCCCACATTTGAACCTCTTCCCCCACCCCCACCTCCTCCACCGAGTCAGGAAACCCCGGTG
TATAGCATGGATGACTTCCCTCCACCTCCTCCCCACACTGTATGTGAGGCGCAGCTGGACAGTGAGGATC
CCGAGGGGCCACGCCCCAGCTTCAACAAACTTTCTAAAGTGACAATTGCAAGGGAAAGGCACATGCCTGG
TGCAGCCCATGTGGTAGGTAGTCAGACACTGGCTTCCAGACTCCAAACTTCTATCAAGGGTTCAGAGGCT
GAGTCCACACCACCCTCCTTCATGAGCGTTCACGCCCAACTTGCTGGGTCTCTTGGTGGGCAGCCAGCAC
CCATCCAGACTCAAAGCCTCAGCCATGATCCAGTCAGTGGAACTCAGGGTTTAGAAAAGAAAGTCAGTCC
TGATCCTCAGAAGAGTTCAGAAGACATCAGAACAGAGGCTTTGGCCAAGGAAATTGTCCACCAAGACAAA
TCTCTAGCAGACATTTTGGATCCAGACTCCAGGCTGAAGACAACAATGGACCTGATGGAAGGTTTGTTTC
CCCGAGATGTGAACTTGCTGAAGGAAAACAGTGTAAAGAGGAAGGCCATACAGAGAACTGTCAGCTCTTC
AGGATGTGAAGGCAAGAGGAATGAAGACAAGGAAGCAGTGAGCATGTTGGTTAACTGCCCTGCCTACTAC
AGTGTGTCTGCTCCCAAGGCTGAGCTACTGAACAAAATCAAAGAGATGCCAGCAGAAGTGAATGAGGAAG
AGGAACAGGCAGATGTCAATGAAAAGAAGGCTGAGCTCATTGGAAGTCTCACCCACAAGCTGGAGACCCT
CCAGGAGGCGAAGGGGAGCCTGCTCACGGACATCAAGCTCAACAACGCCCTGGGAGAAGAGGTGGAGGCT
CTGATCAGCGAGCTCTGCAAGCCCAATGAGTTTGACAAGTATAGGATGTTCATAGGGGATTTGGACAAGG
TGGTCAACCTGCTGCTCTCCCTCTCGGGGCGTCTAGCCCGTGTTGAGAATGTCCTTAGCGGCCTTGGTGA
AGATGCCAGTAATGAAGAAAGGAGCTCTCTTTACGAGAAAAGGAAGATCCTGGCTGGTCAGCATGAGGAT
GCCCGGGAGCTGAAGGAGAACCTGGATCGCAGGGAGCGAGTAGTGCTGGGCATCTTGGCCAATTACCTTT
CAGAGGAGCAGCTCCAGGACTACCAGCACTTCGTGAAAATGAAGTCCACGCTCCTCATTGAGCAACGGAA
GCTGGATGACAAGATCAAGCTGGGCCAGGAGCAGGTCAAGTGTCTGCTGGAGAGCCTGCCCTCAGATTTC
ATTCCCAAGGCTGGGGCCCTGGCTCTGCCCCCAAACCTCACGAGTGAGCCCATTCCTGCTGGGGGCTGTA
CTTTCAGTGGTATTTTCCCAACATTAACCTCTCCACTTTAA

Translation (1996 aa):
MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKL
QAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAA
WSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQSYHSSSSTSDLSNYDHAYL
RRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGR
ERSGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNI
PRGKGVPPPSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSL
GSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGM
LYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLSPVEKKPEATAKYVPSKVHFC
SVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDF
QEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTK
AEDPGRKAAPDLGSHLDRQVSYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQ
GFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEP
LGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGS
PESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEASASASPH
TPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFP
ESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAY
LQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLS
GANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG
FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTP
CPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGP
RGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTS
DPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPV
YSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEA
ESTPPSFMSVHAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDK
SLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAVSMLVNCPAYY
SVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEA
LISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHED
ARELKENLDRRERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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