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Report for CCDS93580.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
93580.1 Public Homo sapiens 4 ANK2 24 110 108 CCDS HistoryNCBI Gene:287Re-query CCDS DB by CCDS ID:93580.1Re-query CCDS DB by GeneID:287See the combined annotation on chromosome 4 in Sequence Viewer

Public since: CCDS release 24, NCBI annotation release 110, Ensembl annotation release 108

Review status: Reviewed (by RefSeq and Havana)

Sequence IDs included in CCDS 93580.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000672684.1 ENSP00000499943.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000672684.1Link to Ensembl Protein Viewer:ENSP00000499943.1Re-query CCDS DB by Nucleotide ID:ENST00000672684Re-query CCDS DB by Protein ID:ENSP00000499943
Original member Current member NCBI NM_001386156.1 NP_001373085.1 Accepted alive Link to Nucleotide Sequence:NM_001386156.1Link to Protein Sequence:NP_001373085.1Re-query CCDS DB by Nucleotide ID:NM_001386156Re-query CCDS DB by Protein ID:NP_001373085Link to BLAST:NP_001373085.1

Chromosomal Locations for CCDS 93580.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 4 (NC_000004.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4See the combined annotation on chromosome 4 in Sequence Viewer

Chromosome Start Stop Links
4 112904494 112904514 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113174416 113174517 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113196368 113196466 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113199011 113199109 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113232161 113232259 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113236987 113237172 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113237599 113237622 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113240485 113240583 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113242111 113242209 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113249764 113249862 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113255735 113255932 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113258050 113258148 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113258313 113258411 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113264897 113264995 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113274452 113274649 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113277837 113277935 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113282675 113282872 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113287605 113287703 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113288388 113288486 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113292416 113292514 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113293440 113293538 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113302767 113302839 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113311255 113311399 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113317707 113317809 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113318517 113318620 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113330246 113330470 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113333054 113333208 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113335846 113336057 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113336577 113336781 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113339226 113339322 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113341688 113341916 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113343017 113343142 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113345900 113346022 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113348276 113348308 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113350228 113350249 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113360823 113360897 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113363338 113363469 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113365039 113365182 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113367566 113367851 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113369514 113369805 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113373090 113373173 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113373285 113373449 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4
4 113381457 113381471 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 4Link to Ensembl Genome Browser on chromosome 4

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (5358 nt):
ATGACCACCATGTTGCAAAAGTCTGACAGCAATGCAAGCTTCCTCCGTGCTGCCAGAGCAGGCAACCTGG
AC
AAAGTTGTGGAATATCTGAAGGGGGGCATAGACATCAATACCTGCAATCAGAATGGACTCAACGCTCT
C
CATCTGGCTGCCAAGGAAGGCCACGTGGGGCTGGTGCAGGAGCTGCTGGGAAGAGGGTCCTCTGTGGAT
TCT
GCCACTAAGAAGGGAAATACCGCTCTTCACATTGCATCTTTGGCTGGACAAGCAGAAGTTGTCAAAG
TT
CTTGTTAAGGAAGGAGCCAATATTAATGCACAGTCTCAGAATGGCTTTACTCCTTTATACATGGCTGC
C
CAAGAGAATCACATTGATGTTGTAAAATATTTGCTGGAAAATGGAGCTAATCAGAGCACTGCTACAGAG
GAT
GGCTTTACTCCTCTAGCTGTGGCACTCCAGCAAGGACACAACCAGGCGGTGGCCATCCTCTTGGAGA
AT
GACACCAAAGGGAAAGTGAGGCTGCCAGCTCTGCATATTGCCGCTAGGAAAGACGACACCAAATCTGC
C
GCACTTCTGCTTCAGAATGACCACAATGCTGACGTACAATCCAAGATGATGGTGAATAGGACAACTGAG
AGT
GGTTTTACCCCTTTGCACATAGCTGCACATTACGGAAATGTCAACGTGGCAACTCTTCTTCTAAACC
GG
GGAGCTGCTGTGGACTTCACAGCCAGGAATGGAATCACTCCTCTGCATGTGGCTTCCAAAAGAGGAAA
T
ACAAACATGGTGAAGCTCTTACTGGATCGAGGCGGTCAGATCGATGCCAAAACTAGGGATGGGTTGACA
CCA
CTTCACTGTGCTGCACGAAGTGGGCATGACCAAGTGGTGGAACTTCTGTTGGAACGGGGTGCCCCCT
TG
CTGGCAAGGACTAAGAATGGGCTGTCTCCACTACACATGGCTGCCCAGGGAGACCACGTGGAATGTGT
G
AAGCACCTGTTACAGCACAAGGCACCTGTTGATGATGTCACCCTAGACTACCTGACAGCCCTCCACGTT
GCT
GCGCACTGTGGCCACTACCGTGTAACCAAACTCCTTTTAGACAAGAGAGCCAATCCGAACGCCAGAG
CC
CTGAATGGTTTTACTCCACTGCACATTGCCTGCAAGAAAAACCGCATCAAAGTCATGGAACTGCTGGT
G
AAATATGGGGCTTCAATCCAAGCTATAACAGAGTCTGGCCTCACACCAATACATGTGGCTGCCTTCATG
GGC
CACTTGAACATTGTCCTCCTTCTGCTGCAGAACGGAGCCTCTCCAGATGTCACTAACATTCGTGGTG
AG
ACGGCACTACACATGGCAGCCCGAGCCGGGCAGGTGGAAGTGGTCCGATGCCTCCTGAGAAATGGTGC
C
CTTGTTGATGCCAGAGCCAGGGAGGAACAGACACCTTTACATATTGCCTCCCGCCTGGGTAAGACAGAA
ATT
GTCCAGCTGCTTCTACAACATATGGCTCATCCAGATGCGGCCACTACAAATGGGTACACACCACTGC
AC
ATCTCTGCCCGGGAGGGCCAGGTGGATGTGGCATCAGTCCTATTGGAAGCAGGAGCAGCCCACTCCTT
A
GCTACCAAGAAGGGTTTTACTCCCCTGCATGTAGCAGCCAAGTATGGAAGCCTGGATGTGGCAAAACTT
CTC
TTGCAACGCCGTGCTGCCGCAGATTCTGCAGGGAAGAATGGCTATACTCCGTTACATATTGCTGCCA
AG
AAGAATCAAATGCAGATAGCTTCCACACTCCTGAACTATGGAGCAGAGACAAACATTGTGACAAAGCA
A
GGAGTAACTCCACTCCATCTGGCCTCGCAGGAGGGGCACACAGATATGGTTACCTTGCTTCTGGATAAG
GGA
GCCAATATCCACATGTCAACTAAGAGTGGACTCACATCCTTACACCTTGCAGCCCAGGAAGATAAAG
TG
AATGTTGCTGATATTCTCACCAAGCATGGAGCTGATCAGGATGCTCATACAAAGCTTGGTTACACACC
T
TTAATTGTGGCCTGTCACTATGGAAATGTGAAAATGGTCAACTTTCTTCTGAAGCAGGGAGCAAATGTT
AAC
GCAAAAACCAAGAACGGCTACACGCCTTTGCACCAGGCCGCTCAGCAGGGTCACACGCACATCATCA
AC
GTCCTGCTCCAGCATGGGGCCAAGCCCAACGCCACCACTGCGAATGGCAACACTGCCTTGGCGATTGC
T
AAGCGTCTGGGCTACATCTCCGTGGTCGACACCCTGAAGGTTGTGACTGAGGAGGTCACCACCACCACC
ACA
ACTATTACAGAAAAACACAAACTAAATGTACCTGAGACGATGACTGAGGTTCTTGATGTTTCTGATG
AA
GAGGGTGATGACACAATGACTGGTGATGGGGGAGAATACCTTAGGCCTGAGGACCTAAAAGAACTGGG
T
GATGACTCACTACCCAGCAGTCAGTTCCTGGATGGTATGAATTACCTGCGATACAGCTTGGAGGGAGGA
CGA
TCTGACAGCCTTCGATCCTTCAGTTCCGACAGGTCTCACACTCTGAGCCATGCCTCCTACCTGAGGG
AC
AGTGCCGTGATGGATGACTCAGTTGTGATTCCCAGTCACCAGGTGTCAACTCTAGCCAAGGAGGCAGA
A
AGGAATTCTTATCGCCTAAGCTGGGGCACTGAGAACTTAGACAACGTGGCTCTTTCTTCTAGTCCTATT
CAT
TCAGGTTTCCTGGTTAGTTTTATGGTGGATGCCCGAGGTGGTGCTATGCGAGGATGCAGACACAATG
GG
CTCCGAATCATTATTCCACCTCGGAAATGTACTGCTCCAACGCGAGTCACCTGCCGACTGGTCAAGCG
C
CACAGACTGGCAACAATGCCTCCAATGGTGGAAGGAGAAGGCCTGGCCAGTCGCCTGATCGAAGTTGGA
CCT
TCTGGTGCTCAGTTCCTTGGGCCTGTGATCGTGGAGATCCCTCACTTTGCGGCCCTTCGAGGAAAGG
AA
AGGGAACTGGTGGTCCTGCGCAGTGAGAATGGGGACAGCTGGAAAGAGCATTTCTGTGACTACACTGA
A
GATGAATTGAATGAAATTCTTAACGGCATGGATGAAGTACTGGATAGCCCAGAAGACCTAGAAAAGAAA
CGA
ATCTGCCGCATCATCACCCGAGACTTCCCACAGTACTTTGCAGTGGTGTCTCGTATCAAACAGGACA
GC
AATCTGATTGGCCCAGAAGGAGGTGTACTGAGCAGCACAGTGGTGCCCCAGGTGCAGGCCGTCTTCCC
A
GAGGGGGCACTCACCAAGCGGATCCGCGTAGGCCTGCAGGCTCAACCTATGCACAGTGAGCTGGTTAAG
AAG
ATCCTAGGCAACAAAGCTACCTTCAGCCCTATAGTCACTTTGGAACCTAGAAGAAGAAAATTCCACA
AA
CCAATTACCATGACCATTCCTGTCCCCAAAGCTTCAAGTGATGTCATGTTGAATGGTTTTGGGGGAGA
T
GCACCAACCTTAAGATTACTATGCAGCATAACAGGTGGAACCACCCCTGCCCAGTGGGAAGATATTACA
GGA
ACTACGCCATTAACATTTGTCAATGAATGTGTTTCCTTTACAACAAACGTGTCTGCCAGGTTCTGGC
TG
ATAGATTGTCGACAGATCCAGGAATCCGTTACTTTTGCATCACAAGTATACAGAGAAATTATCTGCGT
A
CCTTATATGGCCAAATTTGTAGTGTTTGCCAAATCACATGACCCCATTGAAGCCAGGTTGAGGTGTTTC
TGC
ATGACTGATGATAAAGTGGATAAGACCCTTGAACAACAAGAAAATTTTGCTGAGGTGGCCAGAAGCA
GG
GATGTGGAGGTGTTAGAAGGAAAACCCATCTACGTTGATTGTTTCGGCAACTTGGTACCATTAACTAA
A
AGTGGCCAGCATCATATATTCAGTTTTTTTGCCTTCAAAGAAAATAGACTTCCTCTATTTGTCAAGGTA
CGC
GATACGACTCAGGAACCTTGCGGACGACTATCATTTATGAAGGAGCCAAAATCCACGAGAGGCCTGG
TG
CATCAAGCTATTTGCAACTTAAACATCACTTTGCCGATTTATACAAAGGAATCAGAGTCAGATCAAGA
A
CAGGAGGAAGAGATCGATATGACATCAGAAAAAAATCCACAGGATGAGCAGGAACGGATCGAGGAAAGG
CTG
GCTTATATTGCTGATCACCTTGGCTTCAGCTGGACAGAATTAGCAAGAGAACTGGATTTCACTGAGG
AG
CAAATTCATCAAATTCGAATTGAAAATCCCAACTCTCTTCAAGACCAGAGTCATGCACTGTTGAAGTA
C
TGGCTAGAGAGGGATGGGAAACATGCTACAGATACCAACCTCGTTGAATGTCTCACCAAGATCAACCGA
ATG
GATATTGTTCATCTCATGGAGACCAACACAGAACCTCTCCAGGAGCGCATCAGTCATAGTTATGCAG
AA
ATTGAACAGACCATTACACTGGATCATAGTGAAGGGTTCTCGGTACTTCAAGAGGAGTTATGCACTGC
A
CAGCACAAGCAGAAAGAGGAGCAAGCTGTTTCTAAAGAAAGTGAGACCTGCGATCACCCTCCTATCGTC
TCA
GAGGAAGACATTTCTGTTGGTTATTCCACTTTTCAGGATGGCGTCCCCAAAACTGAGGGGGACAGCT
CA
GCAACAGCACTCTTTCCCCAAACTCACAAGGAGCAAGTTCAACAGGATTTCTCAGGGAAAATGCAAGA
C
CTGCCTGAAGAGTCATCTCTGGAATATCAGCAGGAATATTTTGTGACAACTCCAGGAACAGAAACATCA
GAG
ACTCAGAAGGCTATGATAGTACCCAGCTCTCCCAGCAAGACACCTGAGGAAGTTAGCACCCCTGCAG
AG
GAGGAGAAGCTGTACCTCCAGACCCCAACATCCAGCGAGCGGGGAGGCTCTCCCATCATACAAGAACC
C
GAAGAGCCCTCAGAGCACAGAGAGGAGAGCTCTCCGCGGAAAACCAGCCTCGTAATAGTGGAGTCTGCC
GAT
AACCAGCCTGAGACCTGTGAAAGACTCGATGAAGATGCAGCTTTTGAAAAGGGAGACGATATGCCTG
AA
ATACCCCCAGAAACAGTCACAGAAGAAGAATACATTGATGAGCATGGACACACCGTGGTAAAGAAGGT
T
ACTAGGAAAATCATTAGGCGGTATGTATCCTCTGAAGGCACAGAGAAAGAAGAGATTATGGTGCAGGGA
ATG
CCACAGGAACCTGTCAACATCGAGGAAGGGGATGGCTATTCCAAAGTTATAAAGCGTGTTGTATTGA
AG
AGTGACACCGAGCAGTCAGAGGACAACAATGAGTAA


Translation (1785 aa):
MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVD
S
ATK
KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATE
D
GFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSK
MMVNRTTE
S
GFTPLHIAAHYGNVNVATLLLNRGAAVDFTAR
NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLT
P
LHCAARSGHDQVVELLLERGAPLLARTK
NGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV
A
AHCGHYRVTKLLLDKRANPNARAL
NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM
G
HLNIVLLLLQNGASPDVTNI
RGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTE
I
VQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK
KGFTPLHVAAKYGSLDVAKL
L
LQRRAAADSAGK
NGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDK
G
ANIHMSTK
SGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANV
N
AKTK
NGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTT
T
TITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGG
R
SD
SLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPI
H
S
GFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVG
P
SGAQFL
GPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKK
R
ICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQ
AQPMHSELVK
K
ILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSIT
GGTTPAQWEDIT
G
TTPLTFVNECVSFTTNVSA
RFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCF
C
MTDDKVDKTLEQQENFAEVARSRDVE
VLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKV
R
DTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTK
ESESDQEQEEEIDMTSEKNPQDEQERIEER
L
AYIADHLGFSWT
ELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINR
M
DIVHLMETNTEPLQERISHSYAEIEQTITLDHSE
GFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIV
S
EEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEY
FVTTPGTETS
E
TQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESA
D
NQPETCERLDEDAAFEK
GDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQG
M
PQEPVNIEEGDGYSKVIKRVVLKSDTEQSE
DNNE



Links Key
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 Genome Browser Links:   Ensembl Genome Browser
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