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Report for CCDS4027.1 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
4027.1 Public Homo sapiens 5 HMGCR 24 110 108 CCDS HistoryNCBI Gene:3156Re-query CCDS DB by CCDS ID:4027.1Re-query CCDS DB by GeneID:3156See the combined annotation on chromosome 5 in Sequence Viewer

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq and Havana)

Sequence IDs included in CCDS 4027.1

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000287936.9 ENSP00000287936.4 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000287936.9Link to Ensembl Protein Viewer:ENSP00000287936.4Re-query CCDS DB by Nucleotide ID:ENST00000287936Re-query CCDS DB by Protein ID:ENSP00000287936
Original member Current member EBI ENST00000511206.5 ENSP00000426745.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000511206.5Link to Ensembl Protein Viewer:ENSP00000426745.1Re-query CCDS DB by Nucleotide ID:ENST00000511206Re-query CCDS DB by Protein ID:ENSP00000426745
Original member Current member EBI ENST00000680940.1 ENSP00000505561.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000680940.1Link to Ensembl Protein Viewer:ENSP00000505561.1Re-query CCDS DB by Nucleotide ID:ENST00000680940Re-query CCDS DB by Protein ID:ENSP00000505561
Original member Current member EBI ENST00000681271.1 ENSP00000505805.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000681271.1Link to Ensembl Protein Viewer:ENSP00000505805.1Re-query CCDS DB by Nucleotide ID:ENST00000681271Re-query CCDS DB by Protein ID:ENSP00000505805
Original member Current member EBI ENST00000681410.1 ENSP00000506232.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000681410.1Link to Ensembl Protein Viewer:ENSP00000506232.1Re-query CCDS DB by Nucleotide ID:ENST00000681410Re-query CCDS DB by Protein ID:ENSP00000506232
Original member Current member NCBI NM_000859.3 NP_000850.1 MANE Select Accepted alive Link to Nucleotide Sequence:NM_000859.3Link to Protein Sequence:NP_000850.1Re-query CCDS DB by Nucleotide ID:NM_000859Re-query CCDS DB by Protein ID:NP_000850Link to BLAST:NP_000850.1
Original member Current member NCBI NM_001364187.1 NP_001351116.1 Accepted alive Link to Nucleotide Sequence:NM_001364187.1Link to Protein Sequence:NP_001351116.1Re-query CCDS DB by Nucleotide ID:NM_001364187Re-query CCDS DB by Protein ID:NP_001351116Link to BLAST:NP_001351116.1

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_000850.1 888 P04035-1 888 100% 0 0
NP_001351116.1 888 P04035-1 888 100% 0 0

Chromosomal Locations for CCDS 4027.1

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 5 (NC_000005.10)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5See the combined annotation on chromosome 5 in Sequence Viewer

Chromosome Start Stop Links
5 75342606 75342770 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75343853 75343964 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75344245 75344332 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75345574 75345658 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75347204 75347309 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75350042 75350148 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75350258 75350374 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75350789 75350949 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75351068 75351315 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75351424 75351602 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75354503 75354697 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75355056 75355214 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75355365 75355522 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75356343 75356448 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75358657 75358827 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75359170 75359310 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75359398 75359556 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75359985 75360139 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 75360288 75360342 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (2667 nt):
ATGTTGTCAAGACTTTTTCGAATGCATGGCCTCTTTGTGGCCTCCCATCCCTGGGAAGTCATAGTGGGGA
CA
GTGACACTGACCATCTGCATGATGTCCATGAACATGTTTACTGGTAACAATAAGATCTGTGGTTGGAA
T
TATGAATGTCCAAAGTTTGAAGAGGATGTTTTGAGCAGTGACATTATAATTCTGACAATAACACGATGC
ATA
GCCATCCTGTATATTTACTTCCAGTTCCAGAATTTACGTCAACTTGGATCAAAATATATTTTGGGTA
TT
GCTGGCCTTTTCACAATTTTCTCAAGTTTTGTATTCAGTACAGTTGTCATTCACTTCTTAGACAAAGA
A
TTGACAGGCTTGAATGAAGCTTTGCCCTTTTTCCTACTTTTGATTGACCTTTCCAGAGCAAGCACATTA
GCA
AAGTTTGCCCTCAGTTCCAACTCACAGGATGAAGTAAGGGAAAATATTGCTCGTGGAATGGCAATTT
TA
GGTCCTACGTTTACCCTCGATGCTCTTGTTGAATGTCTTGTGATTGGAGTTGGTACCATGTCAGGGGT
A
CGTCAGCTTGAAATTATGTGCTGCTTTGGCTGCATGTCAGTTCTTGCCAACTACTTCGTGTTCATGACT
TTC
TTCCCAGCTTGTGTGTCCTTGGTATTAGAGCTTTCTCGGGAAAGCCGCGAGGGTCGTCCAATTTGGC
AG
CTCAGCCATTTTGCCCGAGTTTTAGAAGAAGAAGAAAATAAGCCGAATCCTGTAACTCAGAGGGTCAA
G
ATGATTATGTCTCTAGGCTTGGTTCTTGTTCATGCTCACAGTCGCTGGATAGCTGATCCTTCTCCTCAA
AAC
AGTACAGCAGATACTTCTAAGGTTTCATTAGGACTGGATGAAAATGTGTCCAAGAGAATTGAACCAA
GT
GTTTCCCTCTGGCAGTTTTATCTCTCTAAAATGATCAGCATGGATATTGAACAAGTTATTACCCTAAG
T
TTAGCTCTCCTTCTGGCTGTCAAGTACATCTTCTTTGAACAAACAGAGACAGAATCTACACTCTCATTA
AAA
AACCCTATCACATCTCCTGTAGTGACACAAAAGAAAGTCCCAGACAATTGTTGTAGACGTGAACCTA
TG
CTGGTCAGAAATAACCAGAAATGTGATTCAGTAGAGGAAGAGACAGGGATAAACCGAGAAAGAAAAGT
T
GAGGTTATAAAACCCTTAGTGGCTGAAACAGATACCCCAAACAGAGCTACATTTGTGGTTGGTAACTCC
TCC
TTACTCGATACTTCATCAGTACTGGTGACACAGGAACCTGAAATTGAACTTCCCAGGGAACCTCGGC
CT
AATGAAGAATGTCTACAGATACTTGGGAATGCAGAGAAAGGTGCAAAATTCCTTAGTGATGCTGAGAT
C
ATCCAGTTAGTCAATGCTAAGCATATCCCAGCCTACAAGTTGGAAACTCTGATGGAAACTCATGAGCGT
GGT
GTATCTATTCGCCGACAGTTACTTTCCAAGAAGCTTTCAGAACCTTCTTCTCTCCAGTACCTACCTT
AC
AGGGATTATAATTACTCCTTGGTGATGGGAGCTTGTTGTGAGAATGTTATTGGATATATGCCCATCCC
T
GTTGGAGTGGCAGGACCCCTTTGCTTAGATGAAAAAGAATTTCAGGTTCCAATGGCAACAACAGAAGGT
TGT
CTTGTGGCCAGCACCAATAGAGGCTGCAGAGCAATAGGTCTTGGTGGAGGTGCCAGCAGCCGAGTCC
TT
GCAGATGGGATGACTCGTGGCCCAGTTGTGCGTCTTCCACGTGCTTGTGACTCTGCAGAAGTGAAAGC
C
TGGCTCGAAACATCTGAAGGGTTCGCAGTGATAAAGGAGGCATTTGACAGCACTAGCAGATTTGCACGT
CTA
CAGAAACTTCATACAAGTATAGCTGGACGCAACCTTTATATCCGTTTCCAGTCCAGGTCAGGGGATG
CC
ATGGGGATGAACATGATTTCAAAGGGTACAGAGAAAGCACTTTCAAAACTTCACGAGTATTTCCCTGA
A
ATGCAGATTCTAGCCGTTAGTGGTAACTATTGTACTGACAAGAAACCTGCTGCTATAAATTGGATAGAG
GGA
AGAGGAAAATCTGTTGTTTGTGAAGCTGTCATTCCAGCCAAGGTTGTCAGAGAAGTATTAAAGACTA
CC
ACAGAGGCTATGATTGAGGTCAACATTAACAAGAATTTAGTGGGCTCTGCCATGGCTGGGAGCATAGG
A
GGCTACAACGCCCATGCAGCAAACATTGTCACCGCCATCTACATTGCCTGTGGACAGGATGCAGCACAG
AAT
GTTGGTAGTTCAAACTGTATTACTTTAATGGAAGCAAGTGGTCCCACAAATGAAGATTTATATATCA
GC
TGCACCATGCCATCTATAGAGATAGGAACGGTGGGTGGTGGGACCAACCTACTACCTCAGCAAGCCTG
T
TTGCAGATGCTAGGTGTTCAAGGAGCATGCAAAGATAATCCTGGGGAAAATGCCCGGCAGCTTGCCCGA
ATT
GTGTGTGGGACCGTAATGGCTGGGGAATTGTCACTTATGGCAGCATTGGCAGCAGGACATCTTGTCA
AA
AGTCACATGATTCACAACAGGTCGAAGATCAATTTACAAGACCTCCAAGGAGCTTGCACCAAGAAGAC
A
GCCTGA


Translation (888 aa):
MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRC
I
AILYIYFQFQNLRQLGSKYIL
GIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTL
A
KFALSSNSQ
DEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMT
F
FPACVSLVLE
LSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQ
N
STADTSKVSLGLDENVSKRIEPSVSLWQFYLS
KMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSL
K
NPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERK
VEVIKPLVAETDTPNRATFVVGNS
S
LLDTSSVLVTQEPEIELPREPRPNEECLQILGNAE
KGAKFLSDAEIIQLVNAKHIPAYKLETLMETHER
G
VSIRRQLLSKKLSEPSSLQYLPYRDYNYSL
VMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEG
C
LVASTNRGCRAIG
LGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFAR
L
QKLHTSIAGRNLYIRFQSRSGDAMGMNMISK
GTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIE
G
RGKSVVCEAVIPAKVVRE
VLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQ
N
VGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQ
MLGVQGACKDNPGENARQLAR
I
VCGTVMAGELSLMAALAAGHLVKSHMIHN
RSKINLQDLQGACTKKTA



Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser