My Bibliography

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Powell Gray B, Song X, Hsu DS, Kratschmer C, Levy M, Barry AP, Sullenger BA. An Aptamer for Broad Cancer Targeting and Therapy. Cancers (Basel). 2020 Oct 31;12(11). doi: 10.3390/cancers12113217. PubMed PMID: 33142831; PubMed Central PMCID: PMC7694147.

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Nguyen MK, Huynh CT, Gilewski A, Wilner SE, Maier KE, Kwon N, Levy M, Alsberg E. Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing. Sci Adv. 2019 Aug;5(8):eaax0801. doi: 10.1126/sciadv.aax0801. eCollection 2019 Aug. PubMed PMID: 31489374; PubMed Central PMCID: PMC6713499.

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Powell Gray B, Kelly L, Ahrens DP, Barry AP, Kratschmer C, Levy M, Sullenger BA. Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4761-4766. doi: 10.1073/pnas.1717705115. Epub 2018 Apr 16. PubMed PMID: 29666232; PubMed Central PMCID: PMC5939073.

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Gianella P, Snapp EL, Levy M. An in vitro compartmentalization-based method for the selection of bond-forming enzymes from large libraries. Biotechnol Bioeng. 2016 Aug;113(8):1647-57. doi: 10.1002/bit.25939. Epub 2016 Feb 8. PubMed PMID: 26806853; PubMed Central PMCID: PMC4925268.

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Kelly L, Kratschmer C, Maier KE, Yan AC, Levy M. Improved Synthesis and In Vitro Evaluation of an Aptamer Ribosomal Toxin Conjugate. Nucleic Acid Ther. 2016 Jun;26(3):156-65. doi: 10.1089/nat.2015.0599. Epub 2016 May 26. PubMed PMID: 27228412; PubMed Central PMCID: PMC4932783.

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Maier KE, Jangra RK, Shieh KR, Cureton DK, Xiao H, Snapp EL, Whelan SP, Chandran K, Levy M. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Mol Ther Nucleic Acids. 2016 May 24;5:e321. doi: 10.1038/mtna.2016.32. PubMed PMID: 27219515.

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Maier KE, Levy M. From selection hits to clinical leads: progress in aptamer discovery. Mol Ther Methods Clin Dev. 2016;5:16014. doi: 10.1038/mtm.2016.14. eCollection 2016. Review. PubMed PMID: 27088106; PubMed Central PMCID: PMC4822646.

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Wilner SE, Sparks SE, Cowburn D, Girvin ME, Levy M. Controlling lipid micelle stability using oligonucleotide headgroups. J Am Chem Soc. 2015 Feb 18;137(6):2171-4. doi: 10.1021/ja512012m. Epub 2015 Feb 3. PubMed PMID: 25634639; PubMed Central PMCID: PMC4861057.

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Trevino SG, Levy M. High-throughput bead-based identification of structure-switching aptamer beacons. Chembiochem. 2014 Sep 5;15(13):1877-81. doi: 10.1002/cbic.201402037. Epub 2014 Jul 23. PubMed PMID: 25056925; PubMed Central PMCID: PMC4161366.

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Wengerter BC, Katakowski JA, Rosenberg JM, Park CG, Almo SC, Palliser D, Levy M. Aptamer-targeted antigen delivery. Mol Ther. 2014 Jul;22(7):1375-1387. doi: 10.1038/mt.2014.51. Epub 2014 Mar 31. PubMed PMID: 24682172; PubMed Central PMCID: PMC4089008.

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Lu WC, Levy M, Kincaid R, Ellington AD. Directed evolution of the substrate specificity of biotin ligase. Biotechnol Bioeng. 2014 Jun;111(6):1071-81. doi: 10.1002/bit.25176. Epub 2014 Jan 25. PubMed PMID: 24375025.

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Padlan CS, Malashkevich VN, Almo SC, Levy M, Brenowitz M, Girvin ME. An RNA aptamer possessing a novel monovalent cation-mediated fold inhibits lysozyme catalysis by inhibiting the binding of long natural substrates. RNA. 2014 Apr;20(4):447-61. doi: 10.1261/rna.043034.113. Epub 2014 Feb 25. PubMed PMID: 24570482; PubMed Central PMCID: PMC3964907.

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Gollihar J, Levy M, Ellington AD. Biochemistry. Many paths to the origin of life. Science. 2014 Jan 17;343(6168):259-60. doi: 10.1126/science.1246704. PubMed PMID: 24436411.

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Costantini L, Snapp E. Probing endoplasmic reticulum dynamics using fluorescence imaging and photobleaching techniques. Curr Protoc Cell Biol. 2013 Sep 24;60:21.7.1-21.7.29. doi: 10.1002/0471143030.cb2107s60. PubMed PMID: 24510787; PubMed Central PMCID: PMC3920296.

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Opazo F, Levy M, Byrom M, Schäfer C, Geisler C, Groemer TW, Ellington AD, Rizzoli SO. Aptamers as potential tools for super-resolution microscopy. Nat Methods. 2012 Oct;9(10):938-9. doi: 10.1038/nmeth.2179. PubMed PMID: 23018995.

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Davidson EA, Meyer AJ, Ellefson JW, Levy M, Ellington AD. An in vitro autogene. ACS Synth Biol. 2012 May 18;1(5):190-6. doi: 10.1021/sb3000113. Epub 2012 May 2. PubMed PMID: 23651157.

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Wilner SE, Wengerter B, Maier K, de Lourdes Borba Magalhães M, Del Amo DS, Pai S, Opazo F, Rizzoli SO, Yan A, Levy M. An RNA alternative to human transferrin: a new tool for targeting human cells. Mol Ther Nucleic Acids. 2012 May 15;1(5):e21. doi: 10.1038/mtna.2012.14. PubMed PMID: 23344001; PubMed Central PMCID: PMC3390244.

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Magalhães ML, Byrom M, Yan A, Kelly L, Li N, Furtado R, Palliser D, Ellington AD, Levy M. A general RNA motif for cellular transfection. Mol Ther. 2012 Mar;20(3):616-24. doi: 10.1038/mt.2011.277. Epub 2012 Jan 10. PubMed PMID: 22233578; PubMed Central PMCID: PMC3294222.

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Patel VL, Mitra S, Harris R, Buxbaum AR, Lionnet T, Brenowitz M, Girvin M, Levy M, Almo SC, Singer RH, Chao JA. Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev. 2012 Jan 1;26(1):43-53. doi: 10.1101/gad.177428.111. PubMed PMID: 22215810; PubMed Central PMCID: PMC3258965.

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Magalhães ML, Czekster CM, Guan R, Malashkevich VN, Almo SC, Levy M. Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci. 2011 Jul;20(7):1145-54. doi: 10.1002/pro.642. Epub 2011 May 12. PubMed PMID: 21520321; PubMed Central PMCID: PMC3149188.

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Chao JA, Patskovsky Y, Patel V, Levy M, Almo SC, Singer RH. ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev. 2010 Jan 15;24(2):148-58. doi: 10.1101/gad.1862910. PubMed PMID: 20080952; PubMed Central PMCID: PMC2807350.

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Davidson EA, VAN Blarcom T, Levy M, Ellington AD. Emulsion based selection of T7 promoters of varying activity. Pac Symp Biocomput. 2010;:433-43. doi: 10.1142/9789814295291_0045. PubMed PMID: 19908395.

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Chen X, Denison L, Levy M, Ellington AD. Direct selection for ribozyme cleavage activity in cells. RNA. 2009 Nov;15(11):2035-45. doi: 10.1261/rna.1635209. Epub 2009 Sep 23. PubMed PMID: 19776159; PubMed Central PMCID: PMC2764470.

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Hall B, Cater S, Levy M, Ellington AD. Kinetic optimization of a protein-responsive aptamer beacon. Biotechnol Bioeng. 2009 Aug 15;103(6):1049-59. doi: 10.1002/bit.22355. PubMed PMID: 19431189.

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Yan AC, Levy M. Aptamers and aptamer targeted delivery. RNA Biol. 2009 Jul-Aug;6(3):316-20. doi: 10.4161/rna.6.3.8808. Epub 2009 Jul 18. Review. PubMed PMID: 19458497; PubMed Central PMCID: PMC4821413.

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Davidson EA, Dlugosz PJ, Levy M, Ellington AD. Directed evolution of proteins in vitro using compartmentalization in emulsions. Curr Protoc Mol Biol. 2009 Jul;Chapter 24:Unit 24.6. doi: 10.1002/0471142727.mb2406s87. PubMed PMID: 19575478.

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Narayanaswamy R, Levy M, Tsechansky M, Stovall GM, O'Connell JD, Mirrielees J, Ellington AD, Marcotte EM. Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10147-52. doi: 10.1073/pnas.0812771106. Epub 2009 Jun 5. PubMed PMID: 19502427; PubMed Central PMCID: PMC2691686.

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Levy M, Ellington AD. Directed evolution of streptavidin variants using in vitro compartmentalization. Chem Biol. 2008 Sep 22;15(9):979-89. doi: 10.1016/j.chembiol.2008.07.017. PubMed PMID: 18804035; PubMed Central PMCID: PMC2615486.

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Tabor JJ, Bayer TS, Simpson ZB, Levy M, Ellington AD. Engineering stochasticity in gene expression. Mol Biosyst. 2008 Jul;4(7):754-61. doi: 10.1039/b801245h. Epub 2008 May 1. PubMed PMID: 18563250; PubMed Central PMCID: PMC2630191.

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Javier DJ, Nitin N, Levy M, Ellington A, Richards-Kortum R. Aptamer-targeted gold nanoparticles as molecular-specific contrast agents for reflectance imaging. Bioconjug Chem. 2008 Jun;19(6):1309-12. doi: 10.1021/bc8001248. Epub 2008 May 31. PubMed PMID: 18512972; PubMed Central PMCID: PMC2651625.

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Sokolov K, Nida D, Descour M, Lacy A, Levy M, Hall B, Dharmawardhane S, Ellington A, Korgel B, Richards-Kortum R. Molecular optical imaging of therapeutic targets of cancer. Adv Cancer Res. 2007;96:299-344. doi: 10.1016/S0065-230X(06)96011-4. Review. PubMed PMID: 17161684.

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Chu TC, Marks JW 3rd, Lavery LA, Faulkner S, Rosenblum MG, Ellington AD, Levy M. Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Res. 2006 Jun 15;66(12):5989-92. doi: 10.1158/0008-5472.CAN-05-4583. PubMed PMID: 16778167.

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Chu TC, Twu KY, Ellington AD, Levy M. Aptamer mediated siRNA delivery. Nucleic Acids Res. 2006 Jun 1;34(10):e73. doi: 10.1093/nar/gkl388. PubMed PMID: 16740739; PubMed Central PMCID: PMC1474074.

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Tabor JJ, Levy M, Ellington AD. Deoxyribozymes that recode sequence information. Nucleic Acids Res. 2006;34(8):2166-72. doi: 10.1093/nar/gkl176. Print 2006. PubMed PMID: 16648360; PubMed Central PMCID: PMC1450334.

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Chu TC, Shieh F, Lavery LA, Levy M, Richards-Kortum R, Korgel BA, Ellington AD. Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates. Biosens Bioelectron. 2006 Apr 15;21(10):1859-66. doi: 10.1016/j.bios.2005.12.015. Epub 2006 Feb 21. PubMed PMID: 16495043.

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Levy M, Cater SF, Ellington AD. Quantum-dot aptamer beacons for the detection of proteins. Chembiochem. 2005 Dec;6(12):2163-6. doi: 10.1002/cbic.200500218. PubMed PMID: 16254932.

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Levskaya A, Chevalier AA, Tabor JJ, Simpson ZB, Lavery LA, Levy M, Davidson EA, Scouras A, Ellington AD, Marcotte EM, Voigt CA. Synthetic biology: engineering Escherichia coli to see light. Nature. 2005 Nov 24;438(7067):441-2. doi: 10.1038/nature04405. PubMed PMID: 16306980.

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Pai S, Ellington AD, Levy M. Proximity ligation assays with peptide conjugate 'burrs' for the sensitive detection of spores. Nucleic Acids Res. 2005 Oct 19;33(18):e162. doi: 10.1093/nar/gni150. PubMed PMID: 16237122; PubMed Central PMCID: PMC1258177.

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Levy M, Griswold KE, Ellington AD. Direct selection of trans-acting ligase ribozymes by in vitro compartmentalization. RNA. 2005 Oct;11(10):1555-62. doi: 10.1261/rna.2121705. Epub 2005 Aug 30. PubMed PMID: 16131588; PubMed Central PMCID: PMC1370839.

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Collett JR, Cho EJ, Lee JF, Levy M, Hood AJ, Wan C, Ellington AD. Functional RNA microarrays for high-throughput screening of antiprotein aptamers. Anal Biochem. 2005 Mar 1;338(1):113-23. doi: 10.1016/j.ab.2004.11.027. PubMed PMID: 15707941.

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Cho EJ, Yang L, Levy M, Ellington AD. Using a deoxyribozyme ligase and rolling circle amplification to detect a non-nucleic acid analyte, ATP. J Am Chem Soc. 2005 Feb 23;127(7):2022-3. doi: 10.1021/ja043490u. PubMed PMID: 15713061.

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Hughes RA, Robertson MP, Ellington AD, Levy M. The importance of prebiotic chemistry in the RNA world. Curr Opin Chem Biol. 2004 Dec;8(6):629-33. doi: 10.1016/j.cbpa.2004.09.007. Review. PubMed PMID: 15556407.

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Levy M, Ellington AD. Exponential growth by cross-catalytic cleavage of deoxyribozymogens. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6416-21. doi: 10.1073/pnas.1130145100. Epub 2003 May 12. PubMed PMID: 12743371; PubMed Central PMCID: PMC164461.

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Levy M, Ellington AD. Peptide-templated nucleic acid ligation. J Mol Evol. 2003 May;56(5):607-15. doi: 10.1007/s00239-002-2429-7. PubMed PMID: 12698297.

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Levy M, Ellington AD. In vitro selection of a deoxyribozyme that can utilize multiple substrates. J Mol Evol. 2002 Feb;54(2):180-90. doi: 10.1007/s00239-001-0066-1. PubMed PMID: 11821911.

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Levy M, Ellington AD. Selection of deoxyribozyme ligases that catalyze the formation of an unnatural internucleotide linkage. Bioorg Med Chem. 2001 Oct;9(10):2581-7. doi: 10.1016/s0968-0896(01)00033-5. PubMed PMID: 11557346.

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Sooter LJ, Riedel T, Davidson EA, Levy M, Cox JC, Ellington AD. Toward automated nucleic acid enzyme selection. Biol Chem. 2001 Sep;382(9):1327-34. doi: 10.1515/BC.2001.165. PubMed PMID: 11688716.

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Levy M, Ellington AD. RNA world: catalysis abets binding, but not vice versa. Curr Biol. 2001 Aug 21;11(16):R665-7. doi: 10.1016/s0960-9822(01)00388-8. PubMed PMID: 11525762.

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Levy M, Ellington AD. The descent of polymerization. Nat Struct Biol. 2001 Jul;8(7):580-2. doi: 10.1038/89601. PubMed PMID: 11427883.

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Nelson KE, Robertson MP, Levy M, Miller SL. Concentration by evaporation and the prebiotic synthesis of cytosine. Orig Life Evol Biosph. 2001 Jun;31(3):221-9. doi: 10.1023/a:1010652418557. PubMed PMID: 11434101.