My Bibliography

select

Biggane JP, Xu K, Goldenstein BL, Davis KL, Luger EJ, Davis BA, Jurgens CWD, Perez DM, Porter JE, Doze VA. Pharmacological characterization of the α(2A)-adrenergic receptor inhibiting rat hippocampal CA3 epileptiform activity: comparison of ligand efficacy and potency. J Recept Signal Transduct Res. 2022 Dec;42(6):580-587. doi: 10.1080/10799893.2022.2110896. Epub 2022 Aug 19. PubMed PMID: 35984443; PubMed Central PMCID: PMC10710878.

select

Raihan MO, Espelien BM, Hanson C, McGregor BA, Velaris NA, Alvine TD, Al Golovko S, Bradley DS, Nilles M, Glovko MY, Hur J, Porter JE. Characterization of prostanoids response to Bordetella pertussis antigen BscF and Tdap in LPS-challenged monocytes. Prostaglandins Leukot Essent Fatty Acids. 2022 Jul;182:102452. doi: 10.1016/j.plefa.2022.102452. Epub 2022 May 21. PubMed PMID: 35690004; PubMed Central PMCID: PMC10211250.

select

Raihan MO, Espelien BM, McGregor BA, Hanson C, Brishti A, Velaris NA, Alvine TD, Bradley DS, Nilles M, Golovko MY, Hur J, Porter JE. Modulation of Inflammatory Signaling Molecules in Bordetella pertussis Antigen-Challenged Human Monocytes in Presence of Adrenergic Agonists. Vaccines (Basel). 2022 Feb 17;10(2). doi: 10.3390/vaccines10020321. PubMed PMID: 35214778; PubMed Central PMCID: PMC8879854.

select

Raihan MO, McGregor BA, Velaris NA, Brishti A, Hur J, Porter JE. Method of Microglial DNA-RNA Purification from a Single Brain of an Adult Mouse. Methods Protoc. 2021 Dec 2;4(4). doi: 10.3390/mps4040086. PubMed PMID: 34940397; PubMed Central PMCID: PMC8704779.

select

McGregor BA, Schommer J, Guo K, Raihan MO, Ghribi O, Hur J, Porter JE. Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia. Neuroscience. 2021 Aug 1;468:186-198. doi: 10.1016/j.neuroscience.2021.05.027. Epub 2021 May 31. PubMed PMID: 34082066.

select

Rashmi, More SK, Wang Q, Vomhof-DeKrey EE, Porter JE, Basson MD. ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain. Pharmacol Res Perspect. 2021 Apr;9(2):e00737. doi: 10.1002/prp2.737. PubMed PMID: 33715263; PubMed Central PMCID: PMC7955952.

select

McGregor BA, Eid S, Rumora AE, Murdock B, Guo K, de Anda-Jáuregui G, Porter JE, Feldman EL, Hur J. Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy. Sci Rep. 2018 Dec 5;8(1):17678. doi: 10.1038/s41598-018-36098-5. PubMed PMID: 30518872; PubMed Central PMCID: PMC6281650.

select

Cilz NI, Porter JE, Lei S. A protocol for preparation and transfection of rat entorhinal cortex organotypic cultures for electrophysiological whole-cell recordings. MethodsX. 2017;4:360-371. doi: 10.1016/j.mex.2017.10.003. eCollection 2017. PubMed PMID: 29071214; PubMed Central PMCID: PMC5651549.

select

Manocha GD, Floden AM, Rausch K, Kulas JA, McGregor BA, Rojanathammanee L, Puig KR, Puig KL, Karki S, Nichols MR, Darland DC, Porter JE, Combs CK. APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease. J Neurosci. 2016 Aug 10;36(32):8471-86. doi: 10.1523/JNEUROSCI.4654-15.2016. PubMed PMID: 27511018; PubMed Central PMCID: PMC4978805.

select

Zhang H, Dong H, Cilz NI, Kurada L, Hu B, Wada E, Bayliss DA, Porter JE, Lei S. Neurotensinergic Excitation of Dentate Gyrus Granule Cells via Gαq-Coupled Inhibition of TASK-3 Channels. Cereb Cortex. 2016 Mar;26(3):977-90. doi: 10.1093/cercor/bhu267. Epub 2014 Nov 18. PubMed PMID: 25405940; PubMed Central PMCID: PMC4737601.

select

Xiao Z, Cilz NI, Kurada L, Hu B, Yang C, Wada E, Combs CK, Porter JE, Lesage F, Lei S. Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model. J Neurosci. 2014 May 14;34(20):7027-42. doi: 10.1523/JNEUROSCI.0408-14.2014. PubMed PMID: 24828655; PubMed Central PMCID: PMC4019809.

select

Nopparat C, Porter JE, Ebadi M, Govitrapong P. 1-Methyl-4-phenylpyridinium-induced cell death via autophagy through a Bcl-2/Beclin 1 complex-dependent pathway. Neurochem Res. 2014 Feb;39(2):225-32. doi: 10.1007/s11064-013-1208-8. Epub 2013 Dec 11. PubMed PMID: 24326530.

select

Grisanti LA, Kurada L, Cilz NI, Porter JE, Lei S. Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin. Eur J Pharmacol. 2012 Aug 15;689(1-3):17-24. doi: 10.1016/j.ejphar.2012.05.032. Epub 2012 Jun 7. PubMed PMID: 22683873; PubMed Central PMCID: PMC3402599.

select

Xiao Z, Jaiswal MK, Deng PY, Matsui T, Shin HS, Porter JE, Lei S. Requirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior. Hippocampus. 2012 Jun;22(6):1438-50. doi: 10.1002/hipo.20984. Epub 2011 Nov 10. PubMed PMID: 22072552; PubMed Central PMCID: PMC3288799.

select

Grisanti LA, Woster AP, Dahlman J, Sauter ER, Combs CK, Porter JE. α1-adrenergic receptors positively regulate Toll-like receptor cytokine production from human monocytes and macrophages. J Pharmacol Exp Ther. 2011 Aug;338(2):648-57. doi: 10.1124/jpet.110.178012. Epub 2011 May 13. PubMed PMID: 21571945; PubMed Central PMCID: PMC3141906.

select

Grisanti LA, Perez DM, Porter JE. Modulation of immune cell function by α(1)-adrenergic receptor activation. Curr Top Membr. 2011;67:113-38. doi: 10.1016/B978-0-12-384921-2.00006-9. Review. PubMed PMID: 21771488; PubMed Central PMCID: PMC3624728.

select

Nopparat C, Porter JE, Ebadi M, Govitrapong P. The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy. J Pineal Res. 2010 Nov;49(4):382-9. doi: 10.1111/j.1600-079X.2010.00805.x. Epub 2010 Aug 24. PubMed PMID: 20738755.

select

Deng PY, Xiao Z, Jha A, Ramonet D, Matsui T, Leitges M, Shin HS, Porter JE, Geiger JD, Lei S. Cholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability. J Neurosci. 2010 Apr 14;30(15):5136-48. doi: 10.1523/JNEUROSCI.5711-09.2010. PubMed PMID: 20392936; PubMed Central PMCID: PMC3073615.

select

Grisanti LA, Evanson J, Marchus E, Jorissen H, Woster AP, DeKrey W, Sauter ER, Combs CK, Porter JE. Pro-inflammatory responses in human monocytes are beta1-adrenergic receptor subtype dependent. Mol Immunol. 2010 Mar;47(6):1244-54. doi: 10.1016/j.molimm.2009.12.013. Epub 2010 Jan 29. PubMed PMID: 20116105; PubMed Central PMCID: PMC2862727.

select

Deng PY, Xiao Z, Yang C, Rojanathammanee L, Grisanti L, Watt J, Geiger JD, Liu R, Porter JE, Lei S. GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. Neuron. 2009 Jul 30;63(2):230-43. doi: 10.1016/j.neuron.2009.06.022. PubMed PMID: 19640481; PubMed Central PMCID: PMC2735825.

select

Xiao Z, Deng PY, Rojanathammanee L, Yang C, Grisanti L, Permpoonputtana K, Weinshenker D, Doze VA, Porter JE, Lei S. Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels. J Biol Chem. 2009 Apr 17;284(16):10980-91. doi: 10.1074/jbc.M806760200. Epub 2009 Feb 25. PubMed PMID: 19244246; PubMed Central PMCID: PMC2667783.

select

Rojanathammanee L, Harmon EB, Grisanti LA, Govitrapong P, Ebadi M, Grove BD, Miyagi M, Porter JE. The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestin. Mol Pharmacol. 2009 Apr;75(4):855-65. doi: 10.1124/mol.108.053397. Epub 2009 Jan 27. PubMed PMID: 19176359; PubMed Central PMCID: PMC2684928.

select

Hillman KL, Lei S, Doze VA, Porter JE. Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus. Epilepsy Res. 2009 Apr;84(2-3):97-109. doi: 10.1016/j.eplepsyres.2008.12.007. Epub 2009 Feb 6. PubMed PMID: 19201164; PubMed Central PMCID: PMC2699218.

select

Lei S, Deng PY, Porter JE, Shin HS. Adrenergic facilitation of GABAergic transmission in rat entorhinal cortex. J Neurophysiol. 2007 Nov;98(5):2868-77. doi: 10.1152/jn.00679.2007. Epub 2007 Sep 5. PubMed PMID: 17804573.

select

Deng PY, Poudel SK, Rojanathammanee L, Porter JE, Lei S. Serotonin inhibits neuronal excitability by activating two-pore domain k+ channels in the entorhinal cortex. Mol Pharmacol. 2007 Jul;72(1):208-18. doi: 10.1124/mol.107.034389. Epub 2007 Apr 23. PubMed PMID: 17452494.

select

Jurgens CW, Hammad HM, Lichter JA, Boese SJ, Nelson BW, Goldenstein BL, Davis KL, Xu K, Hillman KL, Porter JE, Doze VA. Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. Mol Pharmacol. 2007 Jun;71(6):1572-81. doi: 10.1124/mol.106.031773. Epub 2007 Mar 6. PubMed PMID: 17341653.

select

Hillman KL, Doze VA, Porter JE. Alpha1A-adrenergic receptors are functionally expressed by a subpopulation of cornu ammonis 1 interneurons in rat hippocampus. J Pharmacol Exp Ther. 2007 Jun;321(3):1062-8. doi: 10.1124/jpet.106.119297. Epub 2007 Mar 2. PubMed PMID: 17337632.

select

Banerjee S, Evanson J, Harris E, Lowe SL, Thomasson KA, Porter JE. Identification of specific calcitonin-like receptor residues important for calcitonin gene-related peptide high affinity binding. BMC Pharmacol. 2006 Jun 15;6:9. doi: 10.1186/1471-2210-6-9. PubMed PMID: 16776831; PubMed Central PMCID: PMC1525162.

select

Hillman KL, Knudson CA, Carr PA, Doze VA, Porter JE. Adrenergic receptor characterization of CA1 hippocampal neurons using real time single cell RT-PCR. Brain Res Mol Brain Res. 2005 Oct 3;139(2):267-76. doi: 10.1016/j.molbrainres.2005.05.033. PubMed PMID: 16005103.

select

Harmon EB, Porter JM, Porter JE. Beta-adrenergic receptor activation in immortalized human urothelial cells stimulates inflammatory responses by PKA-independent mechanisms. Cell Commun Signal. 2005 Aug 9;3:10. doi: 10.1186/1478-811X-3-10. PubMed PMID: 16091148; PubMed Central PMCID: PMC1198236.

select

Hillman KL, Doze VA, Porter JE. Functional characterization of the beta-adrenergic receptor subtypes expressed by CA1 pyramidal cells in the rat hippocampus. J Pharmacol Exp Ther. 2005 Aug;314(2):561-7. doi: 10.1124/jpet.105.084947. Epub 2005 May 20. PubMed PMID: 15908513.

select

Jurgens CW, Boese SJ, King JD, Pyle SJ, Porter JE, Doze VA. Adrenergic receptor modulation of hippocampal CA3 network activity. Epilepsy Res. 2005 Aug-Sep;66(1-3):117-28. doi: 10.1016/j.eplepsyres.2005.07.007. PubMed PMID: 16140503.

select

Jurgens CW, Rau KE, Knudson CA, King JD, Carr PA, Porter JE, Doze VA. Beta1 adrenergic receptor-mediated enhancement of hippocampal CA3 network activity. J Pharmacol Exp Ther. 2005 Aug;314(2):552-60. doi: 10.1124/jpet.105.085332. Epub 2005 May 20. PubMed PMID: 15908512.

select

Murphy TC, Poppe C, Porter JE, Montine TJ, Picklo MJ Sr. 4-Hydroxy-trans-2-nonenoic acid is a gamma-hydroxybutyrate receptor ligand in the cerebral cortex and hippocampus. J Neurochem. 2004 Jun;89(6):1462-70. doi: 10.1111/j.1471-4159.2004.02442.x. PubMed PMID: 15189349.

select

Ren J, Porter JE, Wold LE, Aberle NS, Muralikrishnan D, Haselton JR. Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse. Neurobiol Aging. 2004 Jan;25(1):131-8. doi: 10.1016/s0197-4580(03)00035-6. PubMed PMID: 14675739.

select

Porter JE, Perez DM. Influence of a lysine 331 counterion on the pK(a) of aspartic acid 125: evidence for a salt-bridge interaction and role in alpha(1b)-adrenergic receptor activation. J Pharmacol Exp Ther. 2000 Jan;292(1):440-8. PubMed PMID: 10604981.

select

Porter JE, Perez DM. Characteristics for a salt-bridge switch mutation of the alpha(1b) adrenergic receptor. Altered pharmacology and rescue of constitutive activity. J Biol Chem. 1999 Dec 3;274(49):34535-8. doi: 10.1074/jbc.274.49.34535. PubMed PMID: 10574914.

select

Porter JE, Edelmann SE, Waugh DJ, Piascik MT, Perez DM. The agonism and synergistic potentiation of weak partial agonists by triethylamine in alpha 1-adrenergic receptor activation: evidence for a salt bridge as the initiating process. Mol Pharmacol. 1998 Apr;53(4):766-71. doi: 10.1124/mol.53.4.766. PubMed PMID: 9547369.

select

Zuscik MJ, Porter JE, Gaivin R, Perez DM. Identification of a conserved switch residue responsible for selective constitutive activation of the beta2-adrenergic receptor. J Biol Chem. 1998 Feb 6;273(6):3401-7. doi: 10.1074/jbc.273.6.3401. PubMed PMID: 9452461.

select

Hwa J, Gaivin R, Porter JE, Perez DM. Synergism of constitutive activity in alpha 1-adrenergic receptor activation. Biochemistry. 1997 Jan 21;36(3):633-9. doi: 10.1021/bi962141c. PubMed PMID: 9012678.

select

Porter JE, Hwa J, Perez DM. Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint. J Biol Chem. 1996 Nov 8;271(45):28318-23. doi: 10.1074/jbc.271.45.28318. PubMed PMID: 8910453.

select

Porter JE, Balasubramaniam A, Abel PW, Conlon JM. Differential actions of lamprey peptide methionine-tyrosine at Y1 and Y2 neuropeptide Y receptors. Regul Pept. 1994 Dec 15;54(2-3):489-93. doi: 10.1016/0167-0115(94)90546-0. PubMed PMID: 7716281.

select

Porter JE, Dowd FJ, Abel PW. Atypical alpha-1 adrenergic receptors on the rat parotid gland acinar cell. J Pharmacol Exp Ther. 1992 Dec;263(3):1062-7. PubMed PMID: 1335054.

select

Cheung PH, Dowd FJ, Porter JE, Li LS. A Ca(2+)-ATPase from rat parotid gland plasma membranes has the characteristics of an ecto-ATPase. Cell Signal. 1992 Jan;4(1):25-35. doi: 10.1016/0898-6568(92)90005-s. PubMed PMID: 1533308.

select

Porter JE, Cheung P, Dowd FJ. Calcium uptake in rat parotid gland secretory granules. J Dent Res. 1991 Dec;70(12):1524-7. doi: 10.1177/00220345910700120901. PubMed PMID: 1723082.