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Schlesinger D, Diamant N, Raghu A, Reinertsen E, Young K, Batra P, Pomerantsev E, Stultz CM. A Deep Learning Model for Inferring Elevated Pulmonary Capillary Wedge Pressures From the 12-Lead Electrocardiogram. Jacc. Advances. 2022 March; 1(1):1.
Diamant N, Reinertsen E, Song S, Aguirre AD, Stultz CM, Batra P. Patient contrastive learning: A performant, expressive, and practical approach to electrocardiogram modeling. PLoS Comput Biol. 2022 Feb;18(2):e1009862. doi: 10.1371/journal.pcbi.1009862. eCollection 2022 Feb. PubMed PMID: 35157695; PubMed Central PMCID: PMC8880931.
Morales MA, van den Boomen M, Nguyen C, Kalpathy-Cramer J, Rosen BR, Stultz CM, Izquierdo-Garcia D, Catana C. DeepStrain: A Deep Learning Workflow for the Automated Characterization of Cardiac Mechanics. Front Cardiovasc Med. 2021;8:730316. doi: 10.3389/fcvm.2021.730316. eCollection 2021. PubMed PMID: 34540923; PubMed Central PMCID: PMC8446607.
Myers PD, Ng K, Severson K, Kartoun U, Dai W, Huang W, Anderson FA, Stultz CM. Identifying unreliable predictions in clinical risk models. NPJ Digit Med. 2020;3:8. doi: 10.1038/s41746-019-0209-7. eCollection 2020. PubMed PMID: 31993506; PubMed Central PMCID: PMC6978376.
Myers PD, Huang W, Anderson F, Stultz CM. Choosing Clinical Variables for Risk Stratification Post-Acute Coronary Syndrome. Sci Rep. 2019 Oct 10;9(1):14631. doi: 10.1038/s41598-019-50933-3. PubMed PMID: 31601916; PubMed Central PMCID: PMC6787006.
Bowman SEJ, Backman LRF, Bjork RE, Andorfer MC, Yori S, Caruso A, Stultz CM, Drennan CL. Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. J Biol Inorg Chem. 2019 Sep;24(6):817-829. doi: 10.1007/s00775-019-01681-2. Epub 2019 Jun 27. PubMed PMID: 31250200; PubMed Central PMCID: PMC6754787.
Stultz CM. The Advent of Clinically Useful Deep Learning. JACC Clin Electrophysiol. 2019 May;5(5):587-589. doi: 10.1016/j.jacep.2019.03.006. PubMed PMID: 31122380.
Myers PD, Scirica BM, Stultz CM. Machine Learning Improves Risk Stratification After Acute Coronary Syndrome. Sci Rep. 2017 Oct 4;7(1):12692. doi: 10.1038/s41598-017-12951-x. PubMed PMID: 28978948; PubMed Central PMCID: PMC5627253.
Stultz CM. Computational Chemistry and Machine Learning in Molecular Medicine and Healthcare: Applications from the Molecule to the Patient. John’s Hopkins Institute for Computational Medicine. 2017 May; Baltimore, Maryland, U.S.A..
Burger VM, Vandervelde A, Hendrix J, Konijnenberg A, Sobott F, Loris R, Stultz CM. Hidden States within Disordered Regions of the CcdA Antitoxin Protein. J Am Chem Soc. 2017 Feb 22;139(7):2693-2701. doi: 10.1021/jacs.6b11450. Epub 2017 Feb 8. PubMed PMID: 28124913.
Liu Y, Scirica BM, Stultz CM, Guttag JV. Beatquency domain and machine learning improve prediction of cardiovascular death after acute coronary syndrome. Sci Rep. 2016 Oct 6;6:34540. doi: 10.1038/srep34540. PubMed PMID: 27708350; PubMed Central PMCID: PMC5052591.
Stultz C. Characterizing Disorder to Order transitions in Intrinsically Disordered Proteins. American Chemical Society Annual Meeting. 2016 August; Philadelphia, Pennsylvania, U.S.A..
Ziegler Z, Schmidt M, Gurry T, Burger V, Stultz CM. Mollack: a web server for the automated creation of conformational ensembles for intrinsically disordered proteins. Bioinformatics. 2016 Aug 15;32(16):2545-7. doi: 10.1093/bioinformatics/btw200. Epub 2016 Apr 19. PubMed PMID: 27153636.
Burger VM, Arenas DJ, Stultz CM. A Structure-free Method for Quantifying Conformational Flexibility in proteins. Sci Rep. 2016 Jun 30;6:29040. doi: 10.1038/srep29040. PubMed PMID: 27358108; PubMed Central PMCID: PMC4928179.
A method and apparatus for beat-space frequency domain prediction of cardiovascular death after acute coronary events. USA 9,295,397. 2016 March.
Burger VM, Nolasco DO, Stultz CM. Expanding the Range of Protein Function at the Far End of the Order-Structure Continuum. J Biol Chem. 2016 Mar 25;291(13):6706-13. doi: 10.1074/jbc.R115.692590. Epub 2016 Feb 5. Review. PubMed PMID: 26851282; PubMed Central PMCID: PMC4807258.
Stultz C. Computational Chemistry and Machine Learning in Cardiovascular Medicine: Application to Acute Coronary Syndromes and Patient Risk Stratification Post-ACS. Cardiovascular Research Center Seminar. 2016 March; Charlottesville, VA, USA.
Gurry T, Fisher CK, Schmidt M, Stultz CM. Analyzing Ensembles of Amyloid Proteins Using Bayesian Statistics. Methods Mol Biol. 2016;1345:269-80. doi: 10.1007/978-1-4939-2978-8_17. PubMed PMID: 26453218.
Stultz C. Characterizing Disorder-to-Order Conformational Transitions in Intrinsically Disordered Proteins. Physical Chemistry Seminar. 2015 September; Waltham, MA, USA.
Stultz C. Novel Computational Approaches for the Study and Treatment of Neurodegenerative Disorders. Future University Individuals Program. 2015 August; Lisbon, Portugal.
Stultz C. A rose by any other name would smell as sweet: What is a cardiac biomarker?. GE Global Research, Niskayuna, NY. 2015 April.
Stultz C. The Aggregation Mechanism of Amyloidogenic Proteins involved in Neurodegenerative Disorders. ”, The American Society for Biochemistry and Molecular Biology Annual Meeting, Boston MA.. 2015 March.
Stultz C. Insights into the Aggregation Mechanism of Amyloidogenic Proteins involved in Neurodegenerative Disorders. The 249th National American Chemical Society Meeting, Denver Colorado. 2015 March.
DaSilva LC, Gurry T, Stultz CM. Toward a consensus in protein structure nomenclature. Intrinsically Disord Proteins. 2014;2(1):e970902. doi: 10.4161/idp.29700. eCollection 2014. PubMed PMID: 28232882; PubMed Central PMCID: PMC5314908.
Gurry T, Stultz CM. Mechanism of amyloid-β fibril elongation. Biochemistry. 2014 Nov 11;53(44):6981-91. doi: 10.1021/bi500695g. Epub 2014 Oct 31. PubMed PMID: 25330398.
Zhong C, Gurry T, Cheng AA, Downey J, Deng Z, Stultz CM, Lu TK. Strong underwater adhesives made by self-assembling multi-protein nanofibres. Nat Nanotechnol. 2014 Oct;9(10):858-66. doi: 10.1038/nnano.2014.199. Epub 2014 Sep 21. PubMed PMID: 25240674; PubMed Central PMCID: PMC4191913.
Stultz C. Modeling Intrinsically Disordered Proteins: Application to Amyloid Beta. Martin Karplus Celebration Symposium (in celebration of Martin Karplus’ 2013 Nobel prize in Chemistry), San Francisco California. 2014 October.
Liu Y, Syed Z, Scirica BM, Morrow DA, Guttag JV, Stultz CM. ECG morphological variability in beat space for risk stratification after acute coronary syndrome. J Am Heart Assoc. 2014 Jun 24;3(3):e000981. doi: 10.1161/JAHA.114.000981. PubMed PMID: 24963105; PubMed Central PMCID: PMC4309066.
Stultz C. Research in the Computational Biophysics Group. Stanford University Bioengineering Seminar, Stanford California. 2014 January.
DaSilva L, Gurry T, Stultz C. Towards a Consensus in Protein Structure Nome. Intrinsically disordered proteins. 2014; 2(1):1-2.
Burger V, Gurry T, Stultz C. Intrinsically Disordered Proteins: Where Computation Meets Experiment. Polymers. 2014; 6(10):2684-2719.
Stultz C. The Mechanism of Aβ Fiber Elongation. The 6th International Conference on Bioinformatics and Biomedical Engineering, Beijing, China (Plenary Lecture). 2013 September.
Stultz C. The Mechanism of Aβ Fiber Elongation. Cold Spring Harber Asia Conference: Frontiers in Bioinformatics and Computational Biology, Suzhou, China. 2013 September.
Gee EPS, Yüksel D, Stultz CM, Ingber DE. SLLISWD sequence in the 10FNIII domain initiates fibronectin fibrillogenesis. J Biol Chem. 2013 Jul 19;288(29):21329-21340. doi: 10.1074/jbc.M113.462077. Epub 2013 Jun 5. PubMed PMID: 23740248; PubMed Central PMCID: PMC3774401.
Lu KG, Stultz CM. Insight into the degradation of type-I collagen fibrils by MMP-8. J Mol Biol. 2013 May 27;425(10):1815-25. doi: 10.1016/j.jmb.2013.02.002. Epub 2013 Feb 8. PubMed PMID: 23399546.
Stultz C. Novel Computational Tools for Risk Stratifying Patients Post-ACS. West Roxbury VA Cardiology Grand Rounds, West Roxbury, MA.. 2013 May.
Fisher CK, Ullman O, Stultz CM. Comparative studies of disordered proteins with similar sequences: application to Aβ40 and Aβ42. Biophys J. 2013 Apr 2;104(7):1546-55. doi: 10.1016/j.bpj.2013.02.023. PubMed PMID: 23561531; PubMed Central PMCID: PMC3617440.
Gurry T, Ullman O, Fisher CK, Perovic I, Pochapsky T, Stultz CM. The dynamic structure of α-synuclein multimers. J Am Chem Soc. 2013 Mar 13;135(10):3865-72. doi: 10.1021/ja310518p. Epub 2013 Feb 27. PubMed PMID: 23398399.
Stultz C. Understanding Human Disease with the Aid of Computers. ”. Draper Laboratory, Cambridge, MA.. 2013 February.
Stultz C. Modeling Intrinsically Disordered Proteins. Wellesley College Chemistry Seminar, Wellesley, MA.. 2013 February.
Stultz C. The Role of Intrinsic Disorder in Modulating Collagen Metabolism. NIH Biochemistry and Biophysics Seminar, Bethesda Maryland.. 2013 January.
Liu JS, Schubert CR, Fu X, Fourniol FJ, Jaiswal JK, Houdusse A, Stultz CM, Moores CA, Walsh CA. Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins. Mol Cell. 2012 Sep 14;47(5):707-21. doi: 10.1016/j.molcel.2012.06.025. Epub 2012 Aug 1. PubMed PMID: 22857951; PubMed Central PMCID: PMC3549492.
Stultz C. Biology and Mathematics – A Marriage Made in Heaven or Hell. Mu Alpha Theta, National High School and Two Year College Mathematics Honor Society, Mathematics National Convention, Boston, MA.. 2012 July.
Stultz C. Modeling Disordered Proteins: Are Structural Models of the Unfolded State Correct?. Computational Biophysics to Systems Biology Workshop (CBSB12), Knoxville, Tennessee. 2012 June.
Walker S, Ullman O, Stultz CM. Using intramolecular disulfide bonds in tau protein to deduce structural features of aggregation-resistant conformations. J Biol Chem. 2012 Mar 16;287(12):9591-600. doi: 10.1074/jbc.M111.336107. Epub 2012 Jan 30. PubMed PMID: 22291015; PubMed Central PMCID: PMC3308815.
Stultz C. Designing Drugs for Intrinsically Disordered Proteins: Challenges and Opportunities. OpenEyeCUP XIII Conference 2012, Santa Fe, New Mexico. 2012 March.
Stultz C. Efficient Construction of Ensembles for Disordered Proteins. Pacific Symposium on Biocomputing 2012, Kona Hawaii. 2012 January.
Fisher CK, Ullman O, Stultz CM. Efficient construction of disordered protein ensembles in a Bayesian framework with optimal selection of conformations. Pac Symp Biocomput. 2012;:82-93. PubMed PMID: 22174265; PubMed Central PMCID: PMC3422750.
Ullman O, Fisher CK, Stultz CM. Explaining the structural plasticity of α-synuclein. J Am Chem Soc. 2011 Dec 7;133(48):19536-46. doi: 10.1021/ja208657z. Epub 2011 Nov 14. PubMed PMID: 22029383; PubMed Central PMCID: PMC3227348.
Stultz C. Is Collagen a Disordered Protein?. Vanderbilt University Matrix Biology Seminar. 2011 October.
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