Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
  • Page of 1
LaPointe AT, Sokoloski KJ. De-Coding the Contributions of the Viral RNAs to Alphaviral Pathogenesis. Pathogens. 2021 Jun 19;10(6). doi: 10.3390/pathogens10060771. Review. PubMed PMID: 34205345; PubMed Central PMCID: PMC8233893.
Landers VD, Wilkey DW, Merchant ML, Mitchell TC, Sokoloski KJ. The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling. Viruses. 2021 Feb 27;13(3). doi: 10.3390/v13030377. PubMed PMID: 33673546; PubMed Central PMCID: PMC7997285.
LaPointe AT, Landers VD, Westcott CE, Sokoloski KJ. Production of Noncapped Genomic RNAs Is Critical to Sindbis Virus Disease and Pathogenicity. mBio. 2020 Dec 1;11(6). doi: 10.1128/mBio.02675-20. PubMed PMID: 33262258; PubMed Central PMCID: PMC7733944.
Higgins TS, Wu AW, Illing EA, Sokoloski KJ, Weaver BA, Anthony BP, Hughes N, Ting JY. Intranasal Antiviral Drug Delivery and Coronavirus Disease 2019 (COVID-19): A State of the Art Review. Otolaryngol Head Neck Surg. 2020 Oct;163(4):682-694. doi: 10.1177/0194599820933170. Epub 2020 Jul 14. Review. PubMed PMID: 32660339.
Gebhart NN, Hardy RW, Sokoloski KJ. Comparative analyses of alphaviral RNA:Protein complexes reveals conserved host-pathogen interactions. PLoS One. 2020;15(8):e0238254. doi: 10.1371/journal.pone.0238254. eCollection 2020. PubMed PMID: 32841293; PubMed Central PMCID: PMC7446964.
Carey BD, Akhrymuk I, Dahal B, Pinkham CL, Bracci N, Finstuen-Magro S, Lin SC, Lehman CW, Sokoloski KJ, Kehn-Hall K. Protein Kinase C subtype δ interacts with Venezuelan equine encephalitis virus capsid protein and regulates viral RNA binding through modulation of capsid phosphorylation. PLoS Pathog. 2020 Mar;16(3):e1008282. doi: 10.1371/journal.ppat.1008282. eCollection 2020 Mar. PubMed PMID: 32150585; PubMed Central PMCID: PMC7082041.
Johnson DM, Sokoloski KJ, Jokinen JD, Pfeffer TL, Chu YK, Adcock RS, Chung D, Tretyakova I, Pushko P, Lukashevich IS. Advanced Safety and Genetic Stability in Mice of a Novel DNA-Launched Venezuelan Equine Encephalitis Virus Vaccine with Rearranged Structural Genes. Vaccines (Basel). 2020 Mar 2;8(1). doi: 10.3390/vaccines8010114. PubMed PMID: 32121666; PubMed Central PMCID: PMC7157698.
LaPointe AT, Moreno-Contreras J, Sokoloski KJ. Increasing the Capping Efficiency of the Sindbis Virus nsP1 Protein Negatively Affects Viral Infection. mBio. 2018 Dec 11;9(6). doi: 10.1128/mBio.02342-18. PubMed PMID: 30538185; PubMed Central PMCID: PMC6299483.
Mackenzie-Liu D, Sokoloski KJ, Purdy S, Hardy RW. Encapsidated Host Factors in Alphavirus Particles Influence Midgut Infection of Aedes aegypti. Viruses. 2018 May 16;10(5). doi: 10.3390/v10050263. PubMed PMID: 29772674; PubMed Central PMCID: PMC5977256.
LaPointe AT, Gebhart NN, Meller ME, Hardy RW, Sokoloski KJ. Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions. J Virol. 2018 Apr 1;92(7). doi: 10.1128/JVI.02171-17. Print 2018 Apr 1. PubMed PMID: 29321325; PubMed Central PMCID: PMC5972874.
Warner NL, Jokinen JD, Beier JI, Sokoloski KJ, Lukashevich IS. Mammarenaviral Infection Is Dependent on Directional Exposure to and Release from Polarized Intestinal Epithelia. Viruses. 2018 Feb 10;10(2). doi: 10.3390/v10020075. PubMed PMID: 29439402; PubMed Central PMCID: PMC5850382.
Sokoloski KJ, Nease LM, May NA, Gebhart NN, Jones CE, Morrison TE, Hardy RW. Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants. PLoS Pathog. 2017 Jun;13(6):e1006473. doi: 10.1371/journal.ppat.1006473. eCollection 2017 Jun. PubMed PMID: 28662211; PubMed Central PMCID: PMC5507600.
Rupp JC, Sokoloski KJ, Gebhart NN, Hardy RW. Alphavirus RNA synthesis and non-structural protein functions. J Gen Virol. 2015 Sep;96(9):2483-2500. doi: 10.1099/jgv.0.000249. Epub 2015 Jul 24. Review. PubMed PMID: 26219641; PubMed Central PMCID: PMC4635493.
Sokoloski KJ, Haist KC, Morrison TE, Mukhopadhyay S, Hardy RW. Noncapped Alphavirus Genomic RNAs and Their Role during Infection. J Virol. 2015 Jun;89(11):6080-92. doi: 10.1128/JVI.00553-15. Epub 2015 Apr 1. PubMed PMID: 25833042; PubMed Central PMCID: PMC4442418.
Sokoloski KJ, Snyder AJ, Liu NH, Hayes CA, Mukhopadhyay S, Hardy RW. Encapsidation of host-derived factors correlates with enhanced infectivity of Sindbis virus. J Virol. 2013 Nov;87(22):12216-26. doi: 10.1128/JVI.02437-13. Epub 2013 Sep 4. PubMed PMID: 24006438; PubMed Central PMCID: PMC3807880.
Patel RK, Burnham AJ, Gebhart NN, Sokoloski KJ, Hardy RW. Role for subgenomic mRNA in host translation inhibition during Sindbis virus infection of mammalian cells. Virology. 2013 Jul 5;441(2):171-81. doi: 10.1016/j.virol.2013.03.022. Epub 2013 Apr 17. PubMed PMID: 23601784; PubMed Central PMCID: PMC3660432.
Ji C, Arnold RJ, Sokoloski KJ, Hardy RW, Tang H, Radivojac P. Extending the coverage of spectral libraries: a neighbor-based approach to predicting intensities of peptide fragmentation spectra. Proteomics. 2013 Mar;13(5):756-65. doi: 10.1002/pmic.201100670. Epub 2013 Feb 4. PubMed PMID: 23303707; PubMed Central PMCID: PMC3733334.
Dickson AM, Anderson JR, Barnhart MD, Sokoloski KJ, Oko L, Opyrchal M, Galanis E, Wilusz CJ, Morrison TE, Wilusz J. Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm. J Biol Chem. 2012 Oct 19;287(43):36229-38. doi: 10.1074/jbc.M112.371203. Epub 2012 Aug 22. PubMed PMID: 22915590; PubMed Central PMCID: PMC3476290.
Sokoloski KJ, Hayes CA, Dunn MP, Balke JL, Hardy RW, Mukhopadhyay S. Sindbis virus infectivity improves during the course of infection in both mammalian and mosquito cells. Virus Res. 2012 Jul;167(1):26-33. doi: 10.1016/j.virusres.2012.03.015. Epub 2012 Mar 30. PubMed PMID: 22484152; PubMed Central PMCID: PMC3361597.
Snyder AJ, Sokoloski KJ, Mukhopadhyay S. Mutating conserved cysteines in the alphavirus e2 glycoprotein causes virus-specific assembly defects. J Virol. 2012 Mar;86(6):3100-11. doi: 10.1128/JVI.06615-11. Epub 2012 Jan 11. PubMed PMID: 22238319; PubMed Central PMCID: PMC3302346.
Sokoloski KJ, Dickson AM, Chaskey EL, Garneau NL, Wilusz CJ, Wilusz J. Sindbis virus usurps the cellular HuR protein to stabilize its transcripts and promote productive infections in mammalian and mosquito cells. Cell Host Microbe. 2010 Aug 19;8(2):196-207. doi: 10.1016/j.chom.2010.07.003. PubMed PMID: 20709296; PubMed Central PMCID: PMC2929003.
Sokoloski KJ, Chaskey EL, Wilusz J. Virus-mediated mRNA decay by hyperadenylation. Genome Biol. 2009;10(8):234. doi: 10.1186/gb-2009-10-8-234. Epub 2009 Aug 11. Review. PubMed PMID: 19678916; PubMed Central PMCID: PMC2745759.
Sokoloski K, Anderson JR, Wilusz J. Development of an in vitro mRNA decay system in insect cells. Methods Mol Biol. 2008;419:277-88. doi: 10.1007/978-1-59745-033-1_19. PubMed PMID: 18369990; NIHMSID:NIHMS78087.
Garneau NL, Sokoloski KJ, Opyrchal M, Neff CP, Wilusz CJ, Wilusz J. The 3' untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells. J Virol. 2008 Jan;82(2):880-92. doi: 10.1128/JVI.01205-07. Epub 2007 Oct 31. PubMed PMID: 17977976; PubMed Central PMCID: PMC2224598.
Sokoloski KJ, Wilusz J, Wilusz CJ. The preparation and applications of cytoplasmic extracts from mammalian cells for studying aspects of mRNA decay. Methods Enzymol. 2008;448:139-63. doi: 10.1016/S0076-6879(08)02608-6. PubMed PMID: 19111175.
Sokoloski KJ, Wilusz CJ, Wilusz J. Viruses: overturning RNA turnover. RNA Biol. 2006 Oct;3(4):140-4. doi: 10.4161/rna.3.4.4076. Epub 2006 Oct 27. Review. PubMed PMID: 17375004.
Opyrchal M, Anderson JR, Sokoloski KJ, Wilusz CJ, Wilusz J. A cell-free mRNA stability assay reveals conservation of the enzymes and mechanisms of mRNA decay between mosquito and mammalian cell lines. Insect Biochem Mol Biol. 2005 Dec;35(12):1321-34. doi: 10.1016/j.ibmb.2005.08.004. Epub 2005 Sep 9. PubMed PMID: 16291088.
What would you like to do?
  • Page of 1