Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence.
Razvi E, Whitfield GB, Reichhardt C, Dreifus JE, Willis AR, Gluscencova OB, Gloag ES, Awad TS, Rich JD, da Silva DP, Bond W, Le Mauff F, Sheppard DC, Hatton BD, Stoodley P, Reinke AW, Boulianne GL, Wozniak DJ, Harrison JJ, Parsek MR, Howell PL.
Razvi E, et al. Among authors: stoodley p.
NPJ Biofilms Microbiomes. 2023 Feb 2;9(1):7. doi: 10.1038/s41522-023-00375-7.
NPJ Biofilms Microbiomes. 2023.
PMID: 36732330
Free PMC article.
While genes encoding glycoside hydrolases have long been linked to biofilm exopolysaccharide biosynthesis, their physiological role in biofilm development is unclear. ...We show that the generation of secreted Pel contributes to the biomechanical properties of the …
While genes encoding glycoside hydrolases have long been linked to biofilm exopolysaccharide biosynthesis, their physiological role i …