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    nfatc2a nuclear factor of activated T cells 2a [ Xiphophorus maculatus (southern platyfish) ]

    Gene ID: 102233108, updated on 10-Mar-2024

    Summary

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    Gene symbol
    nfatc2a
    Gene description
    nuclear factor of activated T cells 2a
    See related
    Ensembl:ENSXMAG00000003976
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xiphophorus maculatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
    Also known as
    nfatc2
    Orthologs
    human zebrafish all
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    Genomic context

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    See nfatc2a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current X_maculatus-5.0-male (GCF_002775205.1) 1 NC_036443.1 (28135098..28162414)
    101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005373233.1 (31896..55087)

    Chromosome 1 - NC_036443.1Genomic Context describing neighboring genes Neighboring gene spalt-like transcription factor 4 Neighboring gene ATPase phospholipid transporting 9A (putative) Neighboring gene potassium voltage-gated channel, subfamily G, member 1 Neighboring gene v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor of activated T-cells, cytoplasmic 2
    Names
    nuclear factor of activated T cells 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference X_maculatus-5.0-male Primary Assembly

    Genomic

    1. NC_036443.1 Reference X_maculatus-5.0-male Primary Assembly

      Range
      28135098..28162414
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023341142.1 → XP_023196910.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X3

      UniProtKB/TrEMBL
      M3ZP49
      Related
      ENSXMAP00000003992.2, ENSXMAT00000003997.2
      Conserved Domains (2) summary
      cd01178
      Location:511 → 611
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
      cl08275
      Location:332 → 506
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

    2. XM_014474904.2 → XP_014330390.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X1

      UniProtKB/TrEMBL
      M3ZP49
      Conserved Domains (2) summary
      cd01178
      Location:535 → 635
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
      cl08275
      Location:356 → 530
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

    3. XM_023341134.1 → XP_023196902.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X2

      UniProtKB/TrEMBL
      A0A3B5QNP8, M3ZP49
      Related
      ENSXMAP00000033054.1, ENSXMAT00000029732.1
      Conserved Domains (2) summary
      cd01178
      Location:535 → 635
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
      cl08275
      Location:356 → 530
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
    Nucleotide Protein Strain
    Heading Accession and Version

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