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    nr1i3 nuclear receptor subfamily 1 group I member 3 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100495136, updated on 4-Nov-2024

    Summary

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    Official Symbol
    nr1i3provided by Xenbase
    Official Full Name
    nuclear receptor subfamily 1 group I member 3provided by Xenbase
    Primary source
    Xenbase:XB-GENE-479859
    See related
    Ensembl:ENSXETG00000031759 AllianceGenome:Xenbase:XB-GENE-479859
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    CAR; car1; mb67
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nr1i3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (141422071..141454039)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683437.1 (23708..30898, complement)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene myelin protein zero Neighboring gene Purkinje cell protein 4 like 1 Neighboring gene translocase of outer mitochondrial membrane 40 homolog-like Neighboring gene solute carrier family 25 member 44

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary history and functional characterization of the amphibian xenosensor CAR. Mathäs M, et al. Mol Endocrinol, 2012 Jan. PMID 22074953, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor subfamily 1 group I member 3
    Names
    constitutive androstane receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      141422071..141454039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031891477.1 → XP_031747337.1  nuclear receptor subfamily 1 group I member 3 isoform X2

      UniProtKB/TrEMBL
      A0A6I8QWB3, A0A8J1IP21
      Related
      ENSXETP00000061422.3, ENSXETT00000060271.3
      Conserved Domains (2) summary
      cd07156
      Location:58 → 129
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:161 → 441
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

    2. XM_031891476.1 → XP_031747336.1  nuclear receptor subfamily 1 group I member 3 isoform X1

      UniProtKB/TrEMBL
      A0A6I8QWB3, A0A6I8SU65
      Related
      ENSXETP00000101387.2, ENSXETT00000082458.2
      Conserved Domains (2) summary
      cd07156
      Location:63 → 134
      NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
      cl11397
      Location:166 → 446
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
    Nucleotide Protein Strain
    Heading Accession and Version

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