U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    l3mbtl3 L3MBTL3, histone methyl-lysine binding protein [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100496330, updated on 4-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    l3mbtl3provided by Xenbase
    Official Full Name
    L3MBTL3, histone methyl-lysine binding proteinprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-1219135
    See related
    Ensembl:ENSXETG00000014401 AllianceGenome:Xenbase:XB-GENE-1219135
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    mbt1; mbt-1
    Summary
    Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to act upstream of or within chromatin organization and regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human L3MBTL3 (L3MBTL histone methyl-lysine binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See l3mbtl3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (83385749..83414874)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (57630901..57660851)

    Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 244 Neighboring gene serine/arginine-rich splicing factor 4 Neighboring gene transmembrane protein 200B Neighboring gene erythrocyte membrane protein band 4.1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    lethal(3)malignant brain tumor-like protein 3
    Names
    l(3)mbt-like 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      83385749..83414874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002939485.4 → XP_002939531.3  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8J0QVW4
      Conserved Domains (2) summary
      cd09582
      Location:682 → 747
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:185 → 281
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2

    2. XM_004911584.3 → XP_004911641.2  lethal(3)malignant brain tumor-like protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A6I8RCU5
      Related
      ENSXETP00000078761.2, ENSXETT00000080140.2
      Conserved Domains (2) summary
      cd09582
      Location:708 → 773
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:211 → 307
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.